The Incubator

Send us a textThis special episode of The Incubator features guest co-hosts Dr. Amir Ashrafi and Dr. Nim Goldshtrom interviewing Dr. Gil Wernovsky, a pioneer in the field of pediatric cardiac intensive care. The discussion focuses on the evolution of neonatal cardiac care and the upcoming Neoheart 2024 conference.Dr. Wernovsky reflects on the history of pediatric cardiac intensive care, highlighting key developments like surfactant therapy and prostaglandin treatment that revolutionized care for neonates with heart disease. He emphasizes the importance of cross-disciplinary collaboration between neonatologists, cardiologists, and other specialists to provide comprehensive care for these complex patients.The conversation explores the challenges of training future specialists in this field, advocating for dual board certification and early exposure for residents. Dr. Wernovsky stresses the need for understanding both anatomy and physiology in managing neonatal cardiac patients.The hosts and guest discuss the upcoming Neoheart 2024 conference in New York City as an opportunity for professionals to network, share knowledge, and advance the field of neonatal cardiac care. They also highlight available fellowship opportunities for those interested in pursuing specialized training in this area. Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Send us a textThis special edition of The Incubator podcast features a neonatal cardiology journal club discussion hosted by Dr. Nim Goldshtrom and Dr. Adrienne Bischoff. The episode covers several recent studies in neonatal hemodynamics and congenital heart disease, providing insights for clinicians and researchers in the field.Key topics include:The impact of early hemodynamic screening on outcomes in extremely preterm infantsUpdated guidelines for targeted neonatal echocardiographyThe relationship between patent ductus arteriosus and bronchopulmonary dysplasia-associated pulmonary hypertensionUse of vasopressin in newborns with refractory acute pulmonary hypertensionResponse to inhaled nitric oxide in extremely premature infantsPlacental pathology's contribution to brain development in neonates with congenital heart diseasePerioperative brain injury and early neurodevelopment in children with severe congenital heart diseaseThe hosts discuss the clinical implications of these studies and their potential impact on neonatal care. They also highlight the upcoming NeoHeart Conference, encouraging listeners to attend and engage with experts in the field.This episode provides a comprehensive overview of current research in neonatal cardiology, making it valuable for professionals seeking to stay updated on the latest developments in this specialized area. Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Send us a textCardiopulmonary physiological effects of diuretic therapy in preterm infants with chronic pulmonary hypertension.Zhu F, Ibarra Rios D, Joye S, Baczynski M, Rios D, Giesinger RE, McNamara PJ, Jain A.J Perinatol. 2023 Oct;43(10):1288-1294. doi: 10.1038/s41372-023-01742-0. Epub 2023 Aug 7.PMID: 37550529Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Send us a textImpact of early screening echocardiography and targeted PDA treatment on neonatal outcomes in "22-23" week and "24-26" infants.Giesinger RE, Hobson AA, Bischoff AR, Klein JM, McNamara PJ.Semin Perinatol. 2023 Mar;47(2):151721. doi: 10.1016/j.semperi.2023.151721. Epub 2023 Mar 5.PMID: 36882362Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Send us a textVasopressin in newborns with refractory acute pulmonary hypertension.Ouellet S, Drolet C, Morissette G, Pellerin A, Hébert A.Pediatr Res. 2024 May;95(6):1572-1577. doi: 10.1038/s41390-023-02995-3. Epub 2024 Jan 11.PMID: 38212386Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Send us a textPatent Ductus Arteriosus and Bronchopulmonary Dysplasia-Associated Pulmonary Hypertension: A Bayesian Meta-Analysis.Villamor E, van Westering-Kroon E, Gonzalez-Luis GE, Bartoš F, Abman SH, Huizing MJ.JAMA Netw Open. 2023 Nov 1;6(11):e2345299. doi: 10.1001/jamanetworkopen.2023.45299.PMID: 38015504 Free PMC article.Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Send us a textResponse categorization and outcomes in extremely premature infants born at 22-26 weeks gestation that received inhaled nitric oxide for hypoxic respiratory failure.Boly TJ, Dagle JM, Klein JM, Rios DR, McNamara PJ, Giesinger RE.J Perinatol. 2023 Mar;43(3):324-331. doi: 10.1038/s41372-022-01582-4. Epub 2022 Dec 12.PMID: 36509816 Free PMC article.Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Send us a textPlacental Pathology Contributes to Impaired Volumetric Brain Development in Neonates With Congenital Heart Disease.Nijman M, van der Meeren LE, Nikkels PGJ, Stegeman R, Breur JMPJ, Jansen NJG, Ter Heide H, Steenhuis TJ, de Heus R, Bekker MN, Claessens NHP, Benders MJNL; CHD LifeSpan Study Group ‡.J Am Heart Assoc. 2024 Mar 5;13(5):e033189. doi: 10.1161/JAHA.123.033189. Epub 2024 Feb 29.PMID: 38420785 Free PMC article.Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Send us a textPerioperative Brain Injury in Relation to Early Neurodevelopment Among Children with Severe Congenital Heart Disease: Results from a European Collaboration.Neukomm A, Claessens NHP, Bonthrone AF, Stegeman R, Feldmann M, Nijman M, Jansen NJG, Nijman J, Groenendaal F, de Vries LS, Benders MJNL, Breur JMPJ, Haas F, Bekker MN, Logeswaran T, Reich B, Kottke R, Dave H, Simpson J, Pushparajah K, Kelly CJ, Arulkumaran S, Rutherford MA, Counsell SJ, Chew A, Knirsch W, Sprong MCA, van Schooneveld MM, Hagmann C, Latal B; European Association Brain in Congenital Heart Disease (EU-ABC) consortium.J Pediatr. 2024 Mar;266:113838. doi: 10.1016/j.jpeds.2023.113838. Epub 2023 Nov 22.PMID: 37995930 Free article.Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Send us a textIn this episode of the Incubator: At the Bench, we talk with Dr. Erin Plosa who is a neonatologist and physician scientist at Vanderbilt University Medical Center. We learn what inspired Dr. Plosa to pursue neonatology and learn about her background and career as a lung biologist. Dr. Plosa talks about the importance of collaboration in scientific research and highlights her work studying the role of integrins and the extracellular matrix during lung development. She discusses the role of the extracellular matrix in alveologenesis, fusion of the alveolar capillary barrier, and in directing communication between epithelial and endothelial cells. We also discuss Erin's experience with mentorship and career development, including her transition into becoming a mentor and winning mentoring awards. Erin shares her approach to mentoring and the importance of fostering intellectual curiosity. Join us as we learn more about what it takes to build a career as a neonatology physician-scientist and how the extracellular matrix directs lung development and response to injury. Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!