The Incubator

Send us a textIn this episode of The Incubator Podcast Journal Club, Ben and Daphna explore a range of insightful articles that challenge current neonatal care practices. They begin by introducing an exciting new series called "From the Heart," focusing on cardiac journal reviews. Special guests from the EBNEO team join the discussion to dive into a recent trial on oxygen use in delivery room resuscitations for preterm infants. The hosts also examine a trial that investigates the impact of lung recruitment maneuvers before surfactant administration in extremely preterm neonates, exploring whether these techniques could reduce the need for mechanical ventilation.This episode provides in-depth analysis and a balanced discussion about the implications of these findings for everyday neonatal care. With guest appearances from Dr. Abdul Razak and Dr. Kiran Srivastava, the team also debates the latest meta-analysis on initial oxygen concentrations during neonatal resuscitation, offering fresh perspectives on potential changes in clinical practice. Whether you're interested in innovative resuscitation techniques or curious about how recent studies may shape the future of neonatal care, this episode offers thought-provoking insights that every NICU professional should hear. Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Explore the critical role of blood culture volumes in diagnosing neonatal sepsis. The discussion dives into a recent study that emphasizes the significance of proper sample sizes and collection timing. Key findings reveal how adherence to guidelines can impact diagnostic accuracy. Tune in for insights on quality improvement in this vital area of infant healthcare!

Dive into the fascinating world of artificial intelligence as it tackles infant healthcare! Discover how a groundbreaking machine learning algorithm is being validated to identify infants at risk of Hypoxic Ischemic Encephalopathy (HIE). The discussion covers the study's innovative methodology and impressive performance metrics. Understand the potential real-world implications of these findings in clinical practice. This episode sheds light on the intersection of technology and medicine, promising to revolutionize infant care!

In this insightful discussion, Abdul Razak, a neonatal expert from Monash Children's Hospital, dives into critical findings on resuscitating preterm infants. He highlights a meta-analysis suggesting that higher initial oxygen concentrations can significantly reduce in-hospital mortality rates. The conversation touches on innovative data-sharing techniques in neonatal research and the vital need for tailored oxygen protocols. Razak also critiques existing studies, revealing how small changes in oxygen levels can dramatically impact outcomes for the most vulnerable infants.

Send us a textAntenatal magnesium sulphate reduces cerebral palsy after preterm birth, implementation into clinical practice needs to be accelerated globally to benefit preterm babies.Luyt K.Cochrane Database Syst Rev. 2024 Sep 24;9:ED000168. doi: 10.1002/14651858.ED000168.PMID: 39315530 No abstract available.Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Send us a textLung recruitment before surfactant administration in extremely preterm neonates with respiratory distress syndrome (IN-REC-SUR-E): a randomised, unblinded, controlled trial.Vento G, Ventura ML, Pastorino R, van Kaam AH, Carnielli V, Cools F, Dani C, Mosca F, Polglase G, Tagliabue P, Boni L, Cota F, Tana M, Tirone C, Aurilia C, Lio A, Costa S, D'Andrea V, Lucente M, Nigro G, Giordano L, Roma V, Villani PE, Fusco FP, Fasolato V, Colnaghi MR, Matassa PG, Vendettuoli V, Poggi C, Del Vecchio A, Petrillo F, Betta P, Mattia C, Garani G, Solinas A, Gitto E, Salvo V, Gargano G, Balestri E, Sandri F, Mescoli G, Martinelli S, Ilardi L, Ciarmoli E, Di Fabio S, Maranella E, Grassia C, Ausanio G, Rossi V, Motta A, Tina LG, Maiolo K, Nobile S, Messner H, Staffler A, Ferrero F, Stasi I, Pieragostini L, Mondello I, Haass C, Consigli C, Vedovato S, Grison A, Maffei G, Presta G, Perniola R, Vitaliti M, Re MP, De Curtis M, Cardilli V, Lago P, Tormena F, Orfeo L, Gizzi C, Massenzi L, Gazzolo D, Strozzi MCM, Bottino R, Pontiggia F, Berardi A, Guidotti I, Cacace C, Meli V, Quartulli L, Scorrano A, Casati A, Grappone L, Pillow JJ.Lancet Respir Med. 2021 Feb;9(2):159-166. doi: 10.1016/S2213-2600(20)30179-X. Epub 2020 Jul 17.PMID: 32687801 Clinical Trial. Lung Recruitment Before Surfactant Administration in Extremely Preterm Neonates: 2-Year Follow-Up of a Randomized Clinical Trial.Gallini F, De Rose DU, Iuliano R, Romeo DM, Tana M, Paladini A, Fusco FP, Nobile S, Cota F, Tirone C, Aurilia C, Lio A, Esposito A, Costa S, D'Andrea V, Ventura ML, Carnielli V, Dani C, Mosca F, Fumagalli M, Scarpelli G, Giordano L, Fasolato V, Petrillo F, Betta P, Solinas A, Gitto E, Gargano G, Mescoli G, Martinelli S, Di Fabio S, Bernardo I, Tina LG, Staffler A, Stasi I, Mondello I, Scapillati E, Vedovato S, Maffei G, Bove A, Vitaliti M, Terrin G, Lago P, Gizzi C, Strozzi C, Villani PE, Berardi A, Cacace C, Bracaglia G, Pascucci E, Cools F, Pillow JJ, Polglase G, Pastorino R, van Kaam AH, Mercuri E, Orfeo L, Vento G; IN-REC-SUR-E Study Group; Malguzzi S, Rigotti C, Cecchi A, Nigro G, Costabile CD, Roma E, Sindico P, Venafra R, Mattia C, Conversano M, Ballardini E, Manganaro A, Balestri E, Gallo C, Catenazzi P, Astori MG, Maranella E, Grassia C, Maiolo K, Castellano D, Massenzi L, Chiodin E, Gallina MR, Consigli C, Sorrentino E, Bonato S, Mancini M, Perniola R, Giannuzzo S, Tranchina E, Cardilli V, Dito L, Regoli D, Tormena F, Battajon N, Arena R, Allais B, Guidotti I, Roversi F, Meli V, Tulino V, Casati A.JAMA Netw Open. 2024 Sep 3;7(9):e2435347. doi: 10.1001/jamanetworkopen.2024.35347.PMID: 39320892 Free PMC article. Clinical Trial.Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Send us a textIn this episode of Tech Tuesday on The Incubator Podcast, hosted by Daphna, Mark O'Sullivan, PhD, CEO, and co-founder of NeuroBell, discusses their cutting-edge medical device aimed at improving neonatal seizure detection. NeuroBell, a spinoff from the Infant Research Center at University College Cork, has developed a pocket-sized, wireless EEG monitor equipped with AI-based seizure detection for newborns. This device is designed to be user-friendly for bedside staff and eliminates the need for extensive EEG training, making it accessible in hospitals with limited EEG resources.Mark shares the story behind the development of the device, highlighting the challenges of acquiring EEG data due to its small signal and the importance of minimizing seizure burden in newborns. He explains how the device addresses gaps in care by providing real-time seizure detection in settings where traditional EEG monitoring might not be readily available.Currently in clinical trials in Ireland and the U.S., NeuroBell aims to provide a streamlined solution that could be particularly useful in community hospitals and smaller settings. The episode wraps up with Mark's vision for the future of NeuroBell, which includes FDA submission and market release in 2025. Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Dr. Suresh Gautham, Chair of Pediatrics at Nemours Children's Hospital, draws fascinating links between neonatology and detective work in his talk. Meanwhile, Dr. Terrie Inder discusses innovative strategies to enhance neurological outcomes in NICU graduates. Pediatric nephrologist Chryso Pefkaros Katsoufis reveals groundbreaking research on neonatal biomarkers of chronic kidney disease. Finally, Dr. Lauren Ruoss showcases the transformative role of point-of-care ultrasound in neonatal care. These insights highlight the future of pediatric medicine and its exciting advancements.

Send us a textIn this special episode of The Incubator podcast, Ben and Daphna wrap up the 2024 Delphi Neonatal Innovation Conference, sharing their favorite moments and highlights. This episode features the exclusive audio from four captivating Delphi talks. Dr. Suresh Gautham, Chair of Pediatrics at Nemours Children's Hospital, opens with an intriguing talk on "What Neonatologists Can Learn from Sherlock Holmes," drawing parallels between neonatal practice and detective work. Dr. Terrie Inder from CHOC delivers insights in "The Science and Art of Improving Neurological Outcomes in NICU Graduates," blending research with practical care strategies. Pediatric nephrologist Chryso Pefkaros Katsoufis from the University of Miami explores "The Road Less Traveled? Neonatal Biomarkers of Chronic Kidney Disease," shedding light on innovative approaches to CKD in newborns. Finally, Dr. Lauren Ruoss, from Winnie Palmer Hospital, enchants the audience with "Abracadabra! Making POCUS Appear in the NICU," detailing the role of point-of-care ultrasound in neonatal care. Ben and Daphna conclude the episode by previewing exciting upcoming developments for The Incubator network. Don’t miss this unique opportunity to hear from some of the leading voices in neonatal care.Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Send us a textIn this special episode of The Incubator podcast, Ben and Daphna wrap up the 2024 Delphi Neonatal Innovation Conference, sharing their favorite moments and highlights. This episode features the exclusive audio from four captivating Delphi talks. Dr. Suresh Gautham, Chair of Pediatrics at Nemours Children's Hospital, opens with an intriguing talk on "What Neonatologists Can Learn from Sherlock Holmes," drawing parallels between neonatal practice and detective work. Dr. Terrie Inder from CHOC delivers insights in "The Science and Art of Improving Neurological Outcomes in NICU Graduates," blending research with practical care strategies. Pediatric nephrologist Chryso Pefkaros Katsoufis from the University of Miami explores "The Road Less Traveled? Neonatal Biomarkers of Chronic Kidney Disease," shedding light on innovative approaches to CKD in newborns. Finally, Dr. Lauren Ruoss, from Winnie Palmer Hospital, enchants the audience with "Abracadabra! Making POCUS Appear in the NICU," detailing the role of point-of-care ultrasound in neonatal care. Ben and Daphna conclude the episode by previewing exciting upcoming developments for The Incubator network. Don’t miss this unique opportunity to hear from some of the leading voices in neonatal care.Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!