American Journal of Psychiatry Audio

This audio program discusses treatment of postpartum psychosis; predictors of suicidal events among depressed adolescents receiving antidepressant treatment after an unsuccessful trial of an SSRI; whether clinicians can recognize DSM-IV personality disorders from case descriptions based on the Five-Factor Model of personality; a genome-wide scan of families with Mexican or Central American ancestry that identified two new loci likely to harbor genes that carry a predisposition for schizophrenia and schizoaffective disorder; the isolation of a risk allele associated with schizophrenia; and the relationship between neural habituation in the amygdala and social impairments in autism spectrum disorders. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program discusses the psychiatric evaluation and follow-up of patients receiving bariatric surgery; a clinical trial of CBT for patients with a variety of eating disorder diagnoses; a study that measured anticipatory activation in the amygdala and anterior cingulate of untreated patients with generalized anxiety disorder with posttreatment examination of the relationship of this activation to treatment response; a study on obsessions and compulsions in the general population from following members of a birth cohort until age 32; the connections between the use of SSRI antidepressants during pregnancy and the risk of gestational hypertension; the ramifications of giving placebo to depressed adolescents in clinical trials. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program discusses factors related to the emergence of mania during antidepressant treatment for bipolar depression; manic symptoms observed during bipolar depression among STEP-BD participants; the attitude of older adults toward enrollment of noncompetent subjects in Alzheimer’s disease research; the association between cerebral deficits and clinical symptoms in antipsychotic-naive, first-episode schizophrenia patients; whether altered amygdala activity in schizophrenia is related to clinical state or to genetic risk; brain structure in schizophrenia patients with relatively intact cognitive functioning; and an odor-detection sensitivity deficit in patients with schizophrenia and its implications for cyclic AMP signaling. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program discusses treatment of children for whom the differential diagnosis includes bipolar disorder and attention deficit hyperactivity disorder; placebo response in antidepressant trials for children; a longitudinal study comparing cortical thickness in patients with ADHD who took stimulants, patients who didn’t take stimulants, and normally developing youths; an examination of the volume and shape of the basal ganglia in ADHD conducted with large-deformation diffeomorphic metric mapping; a study of disorder-specific brain dysfunction in boys with ADHD only and boys with conduct disorder only; and a report on repeat incarcerations for prisoners with serious mental illness. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program includes a Treatment in Psychiatry feature that focuses on prison inmates with ADHD; the association between sleep disturbance and the recurrence of depression among older adults; melatonin circadian rhythms in pregnancy and the postpartum period among depressed women and those with a personal or family history of depression; effect of interpersonal and social rhythm therapy on occupational functioning for patients with bipolar disorder; trauma, resilience, and recovery in a high-risk African American population; association between reading skills in the general population and a gene for dyslexia; and deficits in GABA markers in schizophrenia. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program features the role of culture in psychodynamic psychotherapy; two clinical trials of antipsychotic medications for children and adolescents; a clinical trial of naltrexone in the treatment of amphetamine dependence; a diagnostic study that identified differences and similarities between depression following bereavement and depression associated with other stressful life events; and an analysis indicating that cognitive function in older adults is influenced by the interaction between cortisol and the genotype for apolipoprotein E. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program features a discussion of drug treatment of breast cancer and depression; highlights a study in which olanzapine was used to treat low body weight and obsessive thinking in women with anorexia nervosa; examines whether compulsive hoarding is a symptom of OCD, a distinct syndrome, or both; discusses a clinical trial of adjunctive aripiprazole for bipolar mania patients partially nonresponsive to valproate or lithium monotherapy; and compares two sets of criteria for diagnosing PTSD in children exposed to motor vehicle accidents. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program highlights the treatment of body dysmorphic disorder, three articles on the effect of parental mood disorders--and their treatment--on child psychopathology outcomes, risk for nicotine dependence, remission from alcohol dependence, and a genome screen for quantitative trait loci influencing schizophrenia and neurocognitive phenotypes. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program presents the diagnosis and treatment of Asberger’s syndrome, new treatments for schizophrenia, the pharmacokinetics of aripiprazole, the relationship of cognition and psychopathology to functional impairment in schizophrenia, brain anatomy comparisons of first-episode and chronic schizophrenia, and new evidence of frontal lobe dysfunction in schizophrenia. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program presents a case discussing the resumption of clozapine treatment after development of neutropenia, antipsychotic treatment of Alzheimer’s disease symptoms, a treatment decision tree for depression in elderly patients, and a possible physiologic marker of panic disorder. Articles can be viewed online at www.ajp.psychiatryonline.org.