American Journal of Psychiatry Audio

This audio program discusses a study showing that alcohol consumption is affected by the interaction of psychosocial stress and a gene involved in circadian rhythm; a treatment article discussing safety considerations for T3 augmentation of antidepressants; a comparison of lithium and valproate for preventing suicidal behavior among bipolar patients with previous suicide attempts; nationwide trends in antipsychotic use for anxiety disorders; and a trial of CBT for depression in Parkinson’s disease. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program discusses the relationship between nearly 100 candidate genes and 12 endophenotypes for schizophrenia; the metabolic effects of switching from olanzapine, quetiapine, or risperidone to aripiprazole; the role of genetics in posttraumatic stress disorder; the relationship between depressive symptoms and inflammation in patients with coronary heart disease; a research article reporting a surprisingly high prevalence of autism spectrum disorder in a total population sample; and a clinical case conference about a suicidal man with an unexpected diagnosis of autism spectrum disorder. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program discusses psychiatric complications of medical marijuana; linkage of depression to a region on chromosome 3; cognitive effects of antipsychotics in demented patients; the relationship of schizophrenia to Toxoplasma gondii and to herpes simplex, type 1; the relationship between cognition and functioning in young people at high risk for psychosis; and outcomes of young people at high risk for psychosis who do not become psychotic. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program discusses combining medications for depression; switching from polypharmacy to monotherapy for schizophrenia; combining gabapentin with naltrexone for alcohol dependence; treatments for refractory depression in older patients; the balance between habit formation and goal-directed behavior displayed by obsessive-compulsive disorder patients as they perform an instrumental learning exercise; and the ability of soldiers’ visual fixation on emotional stimuli to predict PTSD and depressive symptoms after deployment. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program discusses the relationship between remission of depression in mothers and psychiatric symptoms in their children; brain structure in childhood- versus adolescent-onset conduct disorder; an apparent case of postpartum psychosis that turned out to be a late-onset urea cycle disorder; how stress affects decision making in patients who’ve been abstinent from heroin; ADHD and deficient emotional self-regulation; early outcomes for first-episode schizophrenia treated with oral or depot antipsychotics; and clarifying the use of interpersonal psychotherapy for major depressive disorder. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program discusses treatment for dependence on prescription painkillers; the effect of national health insurance reform on coverage of individuals with severe mental illnesses; predictors of suicide attempts and nonsuicidal self-injury in depressed adolescents; long-term follow-up of deep brain stimulation for treatment-resistant depression; the association of antidepressants with stroke. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program discusses repetitive transcranial magnetic stimulation for depression; nicotine replacement for agitation in schizophrenia patients who smoke; outcomes of mental health screening of soldiers before deployment; a functionally relevant measure in clinical trials of drugs to improve cognition in schizophrenia. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program discusses the outcome of risperidone nonadherence in early schizophrenia, a pharmacogenetic approach to treatment for alcohol dependence, the relationship of personality disorders to the course of depression, and new perspectives on the neural processing of emotion in schizophrenia. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program discusses severe mood dysregulation and bipolar disorder in children; a longitudinal study of cortical development in children with varying degrees of hyperactivity; whether gray matter volume in adults being treated for alcohol dependence is related to the time until relapse; a schizophrenia study comparing mortality rates for ziprasidone and olanzapine; use of technology to obtain real-time assessments of symptoms and substance use in schizophrenia patients. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program discusses a follow-up investigation of patients with major depression over intervals as long as 31 years to determine whether subclinical hypomanic symptoms at baseline were related to the later emergence of bipolar disorder; a 7-year study examining whether children who experience abuse, bullying, or accidents are more likely to develop psychotic symptoms; baseline number of glucocorticoid receptors as a possible biomarker of posttraumatic stress symptoms, tested in military personnel with and without high levels of PTSD symptoms after 6 months of deployment; a further examination of the association between suicide and high altitude that included the influence of gun ownership and rural location; and whether the relationship between paternal age and schizophrenia risk is the result of de novo mutations or later fatherhood for men with a predisposition to schizophrenia. Articles can be viewed online at www.ajp.psychiatryonline.org.