American Journal of Psychiatry Audio

This audio program offers a commentary on the Research Domain Criteria project by the Director of NIMH. In addition, it reviews liver injury due to antidepressants, head injury as a risk factor for psychiatric disorders, whether women and men differ in the etiology of depression, the effect of cannabis on working memory in adolescent monkeys, whether a genetic polymorphism affected topiramate’s efficacy for reducing alcohol consumption, and a clinical trial of computer-assisted cognitive-behavioral therapy for cocaine-dependent individuals maintained with methadone. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program examines lurasidone treatment of bipolar depression, both as monotherapy and as an adjunct; psychotherapy for bipolar depression related to comorbid anxiety disorders; a computerized method for rating anxiety; genetic, family, and community risk factors for drug abuse; the risk of autoimmune diseases in individuals with a personal or family history of schizophrenia or related psychosis; and how memory is affected by knowing whether one has a gene variant that increases the risk for Alzheimer’s disease. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program examines the risk of upper gastrointestinal bleeding with short-term use of SSRIs and schizophrenia complicated by hepatitis C and hepatic encephalopathy. It also reports results from a study in which neuropsychological functioning was tracked from childhood to age 38, a study comparing psychoanalytic psychotherapy and CBT for bulimia nervosa, a review of the relation of childhood separation anxiety to adult anxiety disorders, and a review comparing approaches to refractory social anxiety disorder. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program includes a case of folie à deux and infanticide, the DSM-5 changes in sleep disorder classification, and new research on ketamine for treatment-resistant depression. Two reports explore brain structure and functioning in patients with eating disorders. Additional studies examine neural mechanisms of frustration in chronically irritable children and the role of oxytocin in mental illness and its treatment. One study looked at the effect of oxytocin on social threat hypersensitivity in women with borderline personality disorder. Another one analyzed how oxytocin moderates the relationship between maternal depression and child mental health. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program examines relationships between violence and mental illness. This issue looks at psychiatric characteristics of homicide defendants, differences in mental illness between gang members and other men with violent behavior, and aggression in a child with Asperger’s disorder. It also features a study of the relationship between firearms availability and suicide risk, a trial of prazosin for treatment of nightmares in combat-related PTSD, a study comparing cognitive-behavioral therapy and short-term psychodynamic therapy for depression, and a long-term study on the effects of antipsychotics in Alzheimer’s disease. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program contains articles on the behavioral treatment of insomnia in bipolar disorder, the relation of childhood trauma to psychotic experiences, comparing psychodynamic therapy and cognitive-behavioral therapy (CBT) for social anxiety disorder, augmenting antidepressant treatment with CBT for generalized anxiety disorder in older adults, and late-onset agoraphobia in a population study that identified new cases of agoraphobia over 4 years in the elderly. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program contains several articles on the treatment of depression. It examines brain tissue loss in schizophrenia and brain changes in women with childhood histories of sexual and emotional abuse. One perspective article details how advanced paternal age could contribute to neurodevelopmental disorders, a commentary describes the DSM-5 section on neurocognitive disorders, and the Treatment in Psychiatry article describes how to handle psychiatric issues related to interferon treatment. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program contains research that considers clozapine as a first-line treatment for schizophrenia, a recently developed scale for negative symptoms, the new DSM-5 diagnosis disruptive mood dysregulation disorder, the effects of mental health parity in the Federal Employees Health Benefits Program, and a surprising finding on successful aging. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program discusses how ketamine creates its rapid antidepressant effect, skin-picking disorder, the IQ and behavioral problems in children of mothers who took antidepressants during pregnancy comparing them with children whose mothers were depressed but untreated and with children of nondepressed mothers, psychopathology in adolescent offspring of parents with panic disorder or depression, and the continuity of psychiatric disorders between ages 3 and 6. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program discusses a modified approach to bulimia nervosa for patients who are overweight, the role of medical comorbidity and the interaction of NSAIDs and antidepressants, the sensitivity and specificity of the proposed DSM-5 criteria for autism spectrum disorder, a meta-analysis of ADHD to clarify affected neural systems instead of individual regions, and a functional brain imaging study of patients with OCD and their siblings to identify a shared biological characteristic to serve as a marker of OCD. Articles can be viewed online at www.ajp.psychiatryonline.org.