New Books in Science

The Problems of Physics, Reconsidered is based on an in-depth filmed conversation between Howard Burton and Physics Nobel Laureate Tony Leggett. The basis of this conversation is Tony Leggett’s book The Problems of Physics and further explores the insightful plain-speaking itemization that he developed of the physics landscape according to four basic categories—the very small (particle physics), the very large (cosmology), the very complex (condensed matter physics) and the very unclear (foundations of quantum theory)—while providing a thoughtful follow-up analysis from a contemporary perspective to assess how much progress we’ve made and which mysteries remain or have come on the scene since the book was published.Howard Burton is the founder of the Ideas Roadshow, Ideas on Film and host of the Ideas Roadshow Podcast. He can be reached at howard@ideasroadshow.com. Learn more about your ad choices. Visit megaphone.fm/adchoicesSupport our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/science

As algorithms become ever more significant to and embedded in our everyday lives, ever more accessible introductions to them are needed. While several excellent technical and critical treatments have emerged in recent years, i had not come across a book for the general public that would provide a deep sense for the intuitions and motivations behind their development. Chris Bleakley's new book offers this and more: conceptual rigor woven into historical vignettes in a style that i believe general readers will find truly enjoyable to read.Poems that Solve Puzzles: The History and Science of Algorithms (Oxford UP, 2020) is itself a quite poetic book, in which echoes of ideas and variations on themes can be heard throughout. Its stories encompass the early hypothetical and mechanical computers, the charactered rise of weather forecasting, the origins (and lulls) of machine learning, and the sensational competitions between master game players and artificial intelligence. The book traverses a long historical arc, but each episode is a quick read, remarkable in their ability to convey depth and rigor in crisp, plain language. It was a delight to talk with Chris about these and other aspects of his book.Suggested companion works:--Simon Singh, The Code Book--George Dyson, Turing's Cathedral: The Origins of the Digital Universe--Greg Kohs (director), "AlphaGo"Chris Bleakley is Head of the School of Computer Science at University College Dublin. He graduated with a BSc (Hons) degree in Computer Science from Queen's University, Belfast, and a PhD degree in Electronic Engineering from Dublin City University. After college, he was employed as a software consultant by Accenture and, later, as a senior telecommunications researcher at Broadcom Eireann Research.Cory Brunson is an Assistant Professor at the Laboratory for Systems Medicine at the University of Florida. His research focuses on geometric and topological approaches to the analysis of medical and healthcare data. Learn more about your ad choices. Visit megaphone.fm/adchoicesSupport our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/science

A Matter of Energy: Biology From First Principles is based on an in-depth filmed conversation between Howard Burton and Nick Lane, Professor of Evolutionary Biochemistry at University College London and bestselling author. After an inspiring exploration of Nick Lane’s career path, this wide-ranging conversation covers his bioenergetic view of early, evolutionary history, the origin of life and how all complex life is composed of a very particular cell type that we all share, and more.Howard Burton is the founder of the Ideas Roadshow, Ideas on Film and host of the Ideas Roadshow Podcast. He can be reached at howard@ideasroadshow.com. Learn more about your ad choices. Visit megaphone.fm/adchoicesSupport our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/science

Over the past seventy years, the Diagnostic and Statistical Manual of Mental Disorders, or DSM, has evolved from a virtually unknown and little-used pamphlet to an imposing and comprehensive compendium of mental disorder. Its nearly 300 conditions have become the touchstones for the diagnoses that patients receive, students are taught, researchers study, insurers reimburse, and drug companies promote. Although the manual is portrayed as an authoritative corpus of psychiatric knowledge, it is a product of intense political conflicts, dissension, and factionalism. The manual results from struggles among psychiatric researchers and clinicians, different mental health professions, and a variety of patient, familial, feminist, gay, and veterans' interest groups. The DSM is fundamentally a social document that both reflects and shapes the professional, economic, and cultural forces associated with its use.In DSM: A History of Psychiatry's Bible (Johns Hopkins UP, 2021), Allan V. Horwitz examines how the manual, known colloquially as "psychiatry's bible," has been at the center of thinking about mental health in the United States since its original publication in 1952. The first book to examine its entire history, this volume draws on both archival sources and the literature on modern psychiatry to show how the history of the DSM is more a story of the growing social importance of psychiatric diagnoses than of increasing knowledge about the nature of mental disorder. Despite attempts to replace it, Horwitz argues that the DSM persists because its diagnostic entities are closely intertwined with too many interests that benefit from them.This comprehensive treatment should appeal to not only specialists but also anyone who is interested in how diagnoses of mental illness have evolved over the past seven decades—from unwanted and often imposed labels to resources that lead to valued mental health treatments and social services. Galina Limorenko is a doctoral candidate in Neuroscience with a focus on biochemistry and molecular biology of neurodegenerative diseases at EPFL in Switzerland. To discuss and propose the book for an interview you can reach her at galina.limorenko@epfl.ch. Learn more about your ad choices. Visit megaphone.fm/adchoicesSupport our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/science

Nature, it has been said, invites us to eat by appetite and rewards by flavor. But what exactly are flavors? Why are some so pleasing while others are not? Delicious is a supremely entertaining foray into the heart of such questions.With generous helpings of warmth and wit, Rob Dunn and Monica Sanchez offer bold new perspectives on why food is enjoyable and how the pursuit of delicious flavors has guided the course of human history. They consider the role that flavor may have played in the invention of the first tools, the extinction of giant mammals, the evolution of the world’s most delicious and fatty fruits, the creation of beer, and our own sociality. Along the way, you will learn about the taste receptors you didn’t even know you had, the best way to ferment a mastodon, the relationship between Paleolithic art and cheese, and much more.Blending irresistible storytelling with the latest science, Delicious: The Evolution of Flavor and How It Made Us Human (Princeton UP, 2021) is a deep history of flavor that will transform the way you think about human evolution and the gustatory pleasures of the foods we eat.Hussein Mohsen is a PhD/MA Candidate in Computational Biology and Bioinformatics/History of Science and Medicine at Yale University. His research interests include machine learning, cancer genomics, and the history of human genetics. For more about his work, visit http://www.husseinmohsen.com. Learn more about your ad choices. Visit megaphone.fm/adchoicesSupport our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/science

When we think of the forces driving cancer, we don’t necessarily think of evolution. But evolution and cancer are closely linked because the historical processes that created life also created cancer. The Cheating Cell: How Evolution Helps Us Understand and Treat Cancer (Princeton UP, 2020) delves into this extraordinary relationship, and shows that by understanding cancer’s evolutionary origins, researchers can come up with more effective, revolutionary treatments.Athena Aktipis goes back billions of years to explore when unicellular forms became multicellular organisms. Within these bodies of cooperating cells, cheating ones arose, overusing resources and replicating out of control, giving rise to cancer. Aktipis illustrates how evolution has paved the way for cancer’s ubiquity, and why it will exist as long as multicellular life does. Even so, she argues, this doesn’t mean we should give up on treating cancer—in fact, evolutionary approaches offer new and promising options for the disease’s prevention and treatments that aim at long-term management rather than simple eradication. Looking across species—from sponges and cacti to dogs and elephants—we are discovering new mechanisms of tumor suppression and the many ways that multicellular life-forms have evolved to keep cancer under control. By accepting that cancer is a part of our biological past, present, and future—and that we cannot win a war against evolution—treatments can become smarter, more strategic, and more humane.Unifying the latest research from biology, ecology, medicine, and social science, The Cheating Cell challenges us to rethink cancer’s fundamental nature and our relationship to it.Hussein Mohsen is a PhD/MA Candidate in Computational Biology and Bioinformatics/History of Science and Medicine at Yale University. His research interests include machine learning, cancer genomics, and the history of human genetics. For more about his work, visit http://www.husseinmohsen.com. Learn more about your ad choices. Visit megaphone.fm/adchoicesSupport our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/science

Dr Daniel Gibbs is one of 50 million people worldwide with an Alzheimer's disease diagnosis. Unlike most patients with Alzheimer's, however, Dr Gibbs worked as a neurologist for twenty-five years, caring for patients with the very disease now affecting him. Also unusual is that Dr Gibbs had begun to suspect he had Alzheimer's several years before any official diagnosis could be made. Forewarned by genetic testing showing he carried alleles that increased the risk of developing the disease, he noticed symptoms of mild cognitive impairment long before any tests would have alerted him. In A Tattoo on my Brain: A Neurologist's Personal Battle against Alzheimer's Disease (Cambridge UP, 2021), Dr Gibbs documents the effect his diagnosis has had on his life and explains his advocacy for improving early recognition of Alzheimer's. Weaving clinical knowledge from decades caring for dementia patients with his personal experience of the disease, this is an optimistic tale of one man's journey with early-stage Alzheimer's disease.Galina Limorenko is a doctoral candidate in Neuroscience with a focus on biochemistry and molecular biology of neurodegenerative diseases at EPFL in Switzerland. To discuss and propose the book for an interview you can reach her at galina.limorenko@epfl.ch. Learn more about your ad choices. Visit megaphone.fm/adchoicesSupport our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/science

Listen to this interview of Joshua Schimel, Professor of soil ecology at the University of California, Santa Barbara and author of Writing Science: How to Write Papers That Get Cited and Proposals That Get Funded (Oxford UP, 2011). We talk about how writing is research, and about how the Vietnam War was really just one big fat rejected manuscript.Joshua Schimel : "One of the challenges, I think, we have in science is that all the way up through university, we're being taught scientific knowledge. But that isn't really science. That's the product of science. Science is the process of learning new things. And there's this wonderful book, Ignorance: How it drives science, by Stuart Firestein, and the book is elegant in that idea of reminding people that science is about ignorance. Science is about what we don't know and how to figure it out. And so, for example, in a good Introduction to an article, you're not just trying to tell people everything we know about a field, you're trying either to identify the gap in what we know or, as the most important papers do, to locate the error in what we do know: 'We've been thinking about things this one way, but we've been wrong in some part of that thinking.' That's going to really engage the experts." Learn more about your ad choices. Visit megaphone.fm/adchoicesSupport our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/science

There's a lot of hype about robots; some of it is scary and some of it utopian. In this accessible book, two robotics experts reveal the truth about what robots can and can't do, how they work, and what we can reasonably expect their future capabilities to be. It will not only make you think differently about the capabilities of robots; it will make you think differently about the capabilities of humans.Ruth Aylett and Patricia Vargas discuss the history of our fascination with robots—from chatbots and prosthetics to autonomous cars and robot swarms. They show us the ways in which robots outperform humans and the ways they fall woefully short of our superior talents. They explain how robots see, feel, hear, think, and learn; describe how robots can cooperate; and consider robots as pets, butlers, and companions. Finally, they look at robots that raise ethical and social issues: killer robots, sexbots, and robots that might be gunning for your job. Living with Robots: What Every Anxious Human Needs to Know (MIT Press, 2021) equips readers to look at robots concretely—as human-made artifacts rather than placeholders for our anxieties.Find out: •Why robots can swim and fly but find it difficult to walk •Which robot features are inspired by animals and insects•Why we develop feelings for robots •Which human abilities are hard for robots to emulate. Galina Limorenko is a doctoral candidate in Neuroscience with a focus on biochemistry and molecular biology of neurodegenerative diseases at EPFL in Switzerland. To discuss and propose the book for an interview you can reach her at galina.limorenko@epfl.ch. Learn more about your ad choices. Visit megaphone.fm/adchoicesSupport our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/science

Cosmological Conundrums is based on an in-depth filmed conversation between Howard Burton and Justin Khoury, Professor of Physics at the University of Pennsylvania. This thoughtful, extensive conversation gives a window into the world of a practicing cosmologist, the often-considerable gap between formal scientific positions and personal scientific interests and examines a wide range of fascinating topics that his research covers such as the early universe, the Big Bang, dark matter, dark energy, Cosmic Microwave Background, the MOND (Modified Newtonian Dynamics) theory, and more.Howard Burton is the founder of the Ideas Roadshow, Ideas on Film and host of the Ideas Roadshow Podcast. He can be reached at howard@ideasroadshow.com. Learn more about your ad choices. Visit megaphone.fm/adchoicesSupport our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/science