New Books in Science

Listen to this interview of Aaron Clauset, Professor of Computer Science at the University of Colorado at Boulder and in the BioFrontiers Institute. Aaron is also External Faculty at the Santa Fe Institute. We talk about what the science of science can contribute to your career in research.Aaron Clauset : "In science, having good ideas is, in the end, the most important part. You can go a long way, in terms of surviving in the ecosystem of scientific research, on the basis of having really good ideas. Because those ideas can help you get to a good, resource-rich institutional environment. Your ideas can help you cultivate a rich, productive collaboration network that will enable you to be successful over time. For example, a paper that I wrote, looking at the composition and size of collaboration networks and how, once you control for differences between men and women in the way they construct and maintain these different kinds of collaboration networks, productivity differences and impact differences essentially go away. I mean, that's kind of fascinating — that the social network that underlies science ends up being the thing that creates many of the disparities that we superficially see in the ecosystem of scientific research." Learn more about your ad choices. Visit megaphone.fm/adchoicesSupport our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/science

Listen to this interview of Nicolas Christin, Professor at Carnegie Mellon University, jointly appointed in the School of Computer Science and in the department of Engineering and Public Policy. We talk about the luck it takes to succeed in research, and of course too about the initiative shown by successful researchers to seize that luck.Nicolas Christin : "You will get a pretty good understanding of where some research idea has come from if you read the Introduction of the paper very carefully. Because the Introduction will typically start with either a sort of case study, 'Alright, so, x does y and this is what happened to them, and so, yeah, we need to fix that problem' or the Introduction will tell you how the paper inscribes itself in a larger body of work but without going through all the related work, as in, 'Yeah, we are different from A, B, and C in this and that way' but instead like 'Yeah, this is what the state-of-the-art is and this is what we are bringing to the table.' And as you read this, you can back-track it all and then see what the initial spark was, what the key motivation for that whole line of research was. Because in some cases, when you do this careful reading, say, ten years after the fact, you know, when you return to the seminal papers in your field, there you may realize or you may find out that the initial idea came from a case study or from a problem that actually was not a problem at all, because really the thing just became famous because it was applied to a different context. And that is, of course, completely fine. In fact, it tells you something about the serendipity or the randomness of what sticks and what doesn't." Learn more about your ad choices. Visit megaphone.fm/adchoicesSupport our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/science

Is the universe infinite or just really big? With this question, cosmologist Janna Levin announces the central theme of this book, which established her as one of the most direct, unorthodox, and creative voices in contemporary science. As Levin sets out to determine how big "really big" may be, she offers a rare intimate look at the daily life of an innovative physicist, complete with jet lag and the tensions between personal relationships and the extreme demands of scientific exploration. Nimbly explaining geometry, topology, chaos, and string theory, Levin shows how the pattern of hot and cold spots left over from the big bang may one day reveal the size of the cosmos. How the Universe Got Its Spots: Diary of a Finite Time in a Finite Space (Princeton UP, 2023) is a thrilling story of cosmology by one of its leading thinkers. Learn more about your ad choices. Visit megaphone.fm/adchoicesSupport our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/science

What if animals and humans could speak to one another? Tom Mustill—the nature documentarian who went viral when a thirty‑ton humpback whale breached onto his kayak—asks this question in his thrilling investigation into whale science and animal communication.“When a whale is in the water, it is like an iceberg: you only see a fraction of it and have no conception of its size.”On September 12, 2015, Tom Mustill was paddling in a two-person kayak with a friend just off the coast of California. It was cold, but idyllic—until a humpback whale breached, landing on top of them, releasing the energy equivalent of forty hand grenades. He was certain he was about to die, but they both survived, miraculously unscathed. In the interviews that followed the incident, Mustill was left with one question: What could this astonishing encounter teach us?Drawing from his experience as a naturalist and wildlife filmmaker, Mustill started investigating human–whale interactions around the world when he met two tech entrepreneurs who wanted to use artificial intelligence (AI)—originally designed to translate human languages—to discover patterns in the conversations of animals and decode them. As he embarked on a journey into animal eavesdropping technologies, where big data meets big beasts, Mustill discovered that there is a revolution taking place in biology, as the technologies developed to explore our own languages are turned to nature.From seventeenth-century Dutch inventors, to the whaling industry of the nineteenth century, to the cutting edge of Silicon Valley, How to Speak Whale: A Voyage into the Future of Animal Communication (Grand Central Publishing, 2022) examines how scientists and start-ups around the world are decoding animal communications. Whales, with their giant mammalian brains, virtuoso voices, and long, highly social lives, offer one of the most realistic opportunities for this to happen. But what would the consequences of such human animal interaction be?Here are some recordings of whale songs:  Humpback Orca Blue Frances Sacks is a graduate of Wesleyan University where she studied in the Science and Society Program. Learn more about your ad choices. Visit megaphone.fm/adchoicesSupport our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/science

Sleep was taking over Anna's life. Despite multiple alarm clocks and powerful stimulants, the young Atlanta lawyer could sleep for thirty or even fifty hours at a stretch. She stopped working and began losing weight because she couldn't stay awake long enough to eat. Anna's doctors didn't know how to help her until they tried an oddball drug, connected with a hunch that something produced by her body was putting her to sleep.The Woman Who Couldn't Wake Up: Hypersomnia and the Science of Sleepiness (Columbia UP, 2023) tells Anna's story-and the broader story of her diagnosis, idiopathic hypersomnia (IH), a shadowy sibling of narcolepsy that has emerged as a focus of sleep research and patient advocacy. Quinn Eastman explores the science around sleepiness, recounting how researchers have been searching for more than a century for the substances that tip the brain into slumber. He argues that investigation of IH could unlock new understandings of how sleep is regulated and controlled. Eastman foregrounds the experiences of people with IH, relating how publicity around Anna's successful treatment helped others form a community. He shows how a group of patients who felt neglected or dismissed united to steer research toward their little-known disorder.Sharing emerging science and powerful stories, this book testifies to the significance of underrecognized diseases and sheds new light on how our brains function, day and night. It is essential reading for anyone interested in sleep and sleep disorders, including those affected by or seeking to treat them.Melek Firat Altay is a neuroscientist, biologist and musician. Her research focuses on deciphering the molecular and cellular mechanisms of neurodegenerative and neurodevelopmental disorders. Learn more about your ad choices. Visit megaphone.fm/adchoicesSupport our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/science

Medical research saves lives-yet all too often, it is thwarted by a review system supposed to safeguard patients that instead creates needless delays and expense. Institutional Review Boards, which exist at every hospital and medical school that conducts medical research, have ended up imposing such complex, draconian conditions that research is frequently damaged, delayed, and distorted. This is why medical miracles like the COVID-19 vaccines, which were developed at warp speed, are far too rare. Instead, medical research in countless areas is kept at a horse-and-buggy pace. The result: unnecessary suffering and avoidable deaths.From Oversight to Overkill: Inside the Broken System That Blocks Medical Breakthroughs--And How We Can Fix It (Rivertowns Books, 2023) vividly recounts the story behind this crisis, one that remains unknown to the general public. Family physician and ethicist Simon Whitney shows how the IRB system was launched in response to scandals like the notorious Tuskegee syphilis study-and how, in recent decades, this well-intentioned program has become increasingly bureaucratic, convoluted, and stifling.Readers will learn how vital breakthroughs in treating conditions from kidney stones to heart attacks and premature birth have been delayed by IRB red tape, forcing doctors and patients to settle for less-effective treatments. They'll see how ill-informed demands from Congressional leaders that regulators "get tough" on scientists have caused respected research institutions to be shut down-with no benefit to the public. And they'll learn about a balanced, common-sense approach to reforming the system that can free scientists from pointless wheel-spinning while still protecting the public from the risks of unethical or careless experimentation.Until now, the debate about the IRB system's failures has been confined to specialty journals in medicine, law, and ethics. From Oversight to Overkill will finally alert citizens about this little-known crisis with America's medical research system-and what can be done about it. Learn more about your ad choices. Visit megaphone.fm/adchoicesSupport our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/science

Dr. Stephen L. Hauser and a patient named Andrea were both 27 years old when they met. He was an up-and-coming neurologist-in-training; she was a Harvard Law School graduate and White House aide whose brain was being ravaged by an explosive case of multiple sclerosis. It was the 1970s and Dr. Hauser had nothing to treat her with. She lost her ability to speak, swallow and breathe. At her bridal shower just before she was married, she was hooked up to a breathing tube and strapped in a wheelchair so she wouldn’t slump over. Dr. Hauser was so moved by her case he decided to devote his career to MS research.The Face Laughs While the Brain Cries: The Education of a Doctor (St. Martin's Press, 2023) is a riveting memoir that chronicles Dr. Hauser’s 40-year quest to find a treatment for MS, the most common crippler of young adults and a disease that affects millions worldwide. Despite enormous pushback from his field, Dr. Hauser discovered a new culprit for MS, ultimately transforming our understanding of the disease and resulting in the development of a new drug that has dramatically improved the lives of thousands of MS patient.Dr. Hauser, director of the Weill Institute for Neurosciences at the University of California San Francisco, describes a colorful cast of characters who played roles in his upbringing and in his development as a tenacious researcher and compassionate physician. He provides moving stories of patients whose courage and optimism in the face of a debilitating illness were instrumental to the advances made in the fight against MS.Over the course of his journey, Dr. Hauser met resistance from experts at the National Institutes of Health, who called his ideas “biologically implausible,” and the Food and Drug Administration, which put such strict limits on a critical proof-of-concept study he feared it was doomed to fail. Then, when victory finally seemed within reach, corporate takeovers threatened to scuttle the whole effort.The Face Laughs While the Brain Cries is an inspiring, highly readable story that highlights the interplay between basic science and patient care and its crucial role in the quest for new medicines that fight disease and improve our lives.Ron Winslow, a former long-time medical and science reporter and editor at The Wall Street Journal, is a freelance medical and science journalist. His story about Dr. Hauser’s research was published in STAT in March, 1917, when the drug based on the research was approved by the U.S. Food and Drug Administration. Learn more about your ad choices. Visit megaphone.fm/adchoicesSupport our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/science

The human right to science, outlined in the 1948 Universal Declaration of Human Rights and repeated in the 1966 International Covenant on Economic, Social, and Cultural Rights, recognizes everyone's right to "share in scientific advancement and its benefits" and to "enjoy the benefits of scientific progress and its applications." This right also requires state parties to develop and disseminate science, to respect the freedom of scientific research, and to recognize the benefits of international contacts and co-operation in the scientific field.The right to science has never been more important. Even before the COVID-19 health crisis, it was evident that people around the world increasingly rely on science and technology in almost every sphere of their lives from the development of medicines and the treatment of diseases, to transport, agriculture, and the facilitation of global communication. At the same time, however, the value of science has been under attack, with some raising alarm at the emergence of "post-truth" societies. "Dual use" and unintended, because often unforeseen, consequences of emerging technologies are also perceived to be a serious risk.The important role played by science and technology and the potential for dual use makes it imperative to evaluate scientific research and its products not only on their scientific but also on their human rights merits. In Science as a Cultural Human Right (U Pennsylvania Press, 2022), Helle Porsdam argues robustly for the role of the right to science now and in the future. The book analyzes the legal stature of this right, the potential consequences of not establishing it as fundamental, and its connection to global cultural rights. It offers the basis for defending the free and responsible practice of science and ensuring that its benefits are spread globally.Melek Firat Altay is a neuroscientist, biologist and musician. Her research focuses on deciphering the molecular and cellular mechanisms of neurodegenerative and neurodevelopmental disorders. Learn more about your ad choices. Visit megaphone.fm/adchoicesSupport our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/science

Fifty thousand years ago, Homo sapiens was not the only species of humans in the world. There were also Neanderthals in what is now Europe, the Near East, and parts of Eurasia; Hobbits (H. floresiensis) on the island of Flores in Indonesia; Denisovans in Siberia and eastern Eurasia; and H. luzonensis in the Philippines. Tom Higham investigates what we know about these other human species and explores what can be learned from the genetic links between them and us. He also looks at whether H. erectus may have survived into the period when our ancestors first moved into Southeast Asia.Filled with thrilling tales of recent scientific discoveries, Tom Higham book The World Before Us: The New Science Behind Our Human Origins (Yale UP, 2021) offers an engaging synopsis of our current understanding of human origins and raises new and interesting possibilities--particularly concerning what contact, if any, these other species might have had with us prior to their extinction.Melek Firat Altay is a neuroscientist, biologist and musician. Her research focuses on deciphering the molecular and cellular mechanisms of neurodegenerative and neurodevelopmental disorders. Learn more about your ad choices. Visit megaphone.fm/adchoicesSupport our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/science

Kant denied biology the status of a proper science, yet his account of the organism profoundly influenced a range of intellectual disciplines. Andrew Jones's How Kant Matters for Biology: A Philosophical History (University of Wales Press, 2023) examines Kant’s influence on biology in the British Isles by proposing that his influence owes to misunderstandings of his philosophy. Andrew Jones exposes the incompatibility between transcendental realism and scientific naturalism and charts how Kant, nevertheless, influenced various aspects of the scientific method. With this context in mind, Jones examines the extent to which core concepts in contemporary philosophy—natural law, the unity of science, and our understanding of organisms— are compatible with scientific naturalism and proposes new avenues for developing Kant-inspired approaches within contemporary philosophy of science.Özlem Yılmaz is a philosopher of science, with a focus on issues related to plant biology. Learn more about your ad choices. Visit megaphone.fm/adchoicesSupport our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/science