Sarah Stein Greenberg, executive director of Stanford's d.school, shares her insights on design as a powerful problem-solving tool. She discusses the frustrating nature of traditional brainstorms and the value of empathy-driven design in healthcare, illustrated by student projects improving communication in hospitals. Sarah also emphasizes the importance of community engagement in development work and the transformative potential of design in addressing social issues. Additionally, she shares her passion for underwater photography and the patience required to capture marine life beautifully.

Elsa Richardson, a medical historian at the University of Strathclyde and author of "Rumbles: A Curious History of the Gut," discusses the fascinating evolution of our understanding of gut health. She reveals the gripping story of Alexis St. Martin, whose unusual medical condition led to important digestion studies. The conversation delves into the gut-brain connection, illustrating how gut microbiome health impacts emotions and decision-making. Richardson also touches on the journey of writing her book, blending historical insights with modern perspectives on holistic health.

Dan Gilbert, a Harvard psychologist and author of "Stumbling on Happiness," shares his journey from high school dropout to academic success. He discusses the 'end of history illusion,' revealing how we underestimate changes in our preferences over time. Gilbert also delves into perceptions of morality, noting a disconnect between beliefs and reality. He emphasizes valuing relationships over material wealth for happiness and reflects on redefining success and fulfillment through personal anecdotes. His insights encourage self-awareness and embracing simple joys in life.

Moon Duchin, a math professor at Cornell University, explores the intriguing intersection of mathematics and democracy. She discusses the complexities of redistricting and how gerrymandering distorts electoral fairness. The conversation unpacks techniques like 'packing' and 'cracking' in districting and examines the surprising effects of residential segregation on political representation. Duchin also shares insights on innovative voting methods, promoting a more equitable electoral landscape while reflecting on her academic journey and the importance of diversity in the field.

Neil deGrasse Tyson, director of the Hayden Planetarium and a leading voice in science communication, shares his fascinating insights. He reflects on the contentious reclassification of Pluto and the nostalgia around it. The conversation delves into the complexities of inter-species communication and the skepticism surrounding contact with extraterrestrial beings. Tyson also humorously critiques how science can be blended with pop culture to enhance public understanding, showcasing the importance of engaging and accessible science education.

Pete Docter, chief creative officer of Pixar and director of iconic films like 'Soul' and 'Monsters, Inc.', shares insights on Pixar's journey from humble beginnings to animation powerhouse. He discusses the significance of creativity, collaboration, and wrong turns in storytelling. The conversation delves into the emotional depth of animation, balancing artistry with profitability, and the joys and challenges of parenting. Docter reflects on how personal experiences shape narratives that resonate with audiences, making animated stories impactful across generations.

David Eagleman, a Stanford neuroscientist and CEO of Neosensory, shares fascinating insights into the brain's plasticity and sensory substitution. He discusses how our wrists can be trained to interpret sound, enhancing experiences for the deaf. The conversation delves into the purpose of dreams, suggesting they help protect our visual systems. Eagleman also tackles the intriguing concept of Possibilianism and its role in understanding existence, intertwining philosophy with technology in a thought-provoking way.

Richard Reeves, a Senior Fellow at the Brookings Institution and author of "Of Boys and Men," discusses the alarming trends affecting boys and men in education, employment, and mental health. He delves into the gender disparities in academic performance, advocating for innovative solutions like delayed school entry and increased vocational training. Reeves emphasizes the importance of addressing these challenges without undermining women's progress, while also exploring the emotional struggles men face in modern society. His insights call for a balanced approach to gender issues.

Daron Acemoglu, a celebrated MIT professor and 2024 Nobel Prize winner, dives deep into his groundbreaking research on economics. He explores why some nations thrive while others struggle, emphasizing the crucial role of institutions and historical legacies. The conversation tackles the complex interplay between technology and inequality, highlighting how advancements can harm or help society. Acemoglu critiques current tech practices that prioritize profit over human empowerment, all while reflecting on economic shifts since World War II.

David Autor, a renowned MIT professor specializing in labor economics, dives deep into the significant effects of technology and AI on American workers. He discusses the rise of income inequality since the late 1970s and the crucial role education plays in this issue. Autor also explores AI's potential to reshape job roles and empower the middle class, arguing that it can democratize access to skilled work. With insight into the intersection of labor markets and technology, he provides a compelling look at future trends affecting workers.