Medical treatments designed to help people can also be harmful or fatal. Around 2.5 million people die this way each year. So if any kind of medicine makes someone unwell, they or their doctor should report it. Those reports, from nearly every country in the world, go to the Uppsala Monitoring Centre (UMC) in Sweden. As the Centre’s first director, Professor Ivor Ralph Edwards transformed it from a tiny operation with limited horizons into an internationally acclaimed scientific organization at the heart of the World Health Organization’s Programme for International Drug Monitoring. He was then succeeded by his wife, Dr Marie Lindquist.Ian Hembrow's Ralph Edwards: Rare Events--The Inside Story of a Worldwide Quest for Safer Medicines (Springer, 2023) is the story of how a new science developed and a passionate and dedicated pursuit of worldwide medicines safety, with an unerring focus on the welfare of patients. The pioneering work of Ralph, Marie and their collaborators on every continent protected the lives of millions of people. It may yet improve the lives of billions more.Victoria Phillips is a Visiting Fellow at the London School of Economics in the Department of International History. Learn more about your ad choices. Visit megaphone.fm/adchoices

An interview with Donna J. Drucker, author of Contraception, from The MIT Press Essential Knowledge series. We discuss reproductive justice, the history of contraceptive technology and how the future of contraception can offer more choice and more freedom for every kind of person.The development, manufacturing, and use of contraceptive methods from the late nineteenth century to the present, viewed from the perspective of reproductive justice.The beginning of the modern contraceptive era began in 1882, when Dr. Aletta Jacobs opened the first birth control clinic in Amsterdam. The founding of this facility, and the clinical provision of contraception that it enabled, marked the moment when physicians started to take the prevention of pregnancy seriously as a medical concern. In this volume in the MIT Press Essential Knowledge series, Donna Drucker traces the history of modern contraception, outlining the development, manufacturing, and use of contraceptive methods from the opening of Dr. Jacobs's clinic to the present. Drucker approaches the subject from the perspective of reproductive justice: the right to have a child, the right not to have a child, and the right to parent children safely and healthily.Drucker describes contraceptive methods available before the pill, including the diaphragm (dispensed at the Jacobs clinic) and condom, spermicidal jellies, and periodic abstinences. She looks at the development and dissemination of the pill and its chemical descendants; describes technological developments in such non-hormonal contraceptives as the cervical cap and timing methods (including the “rhythm method” favored by the Roman Catholic church); and explains the concept of reproductive justice. Finally, Drucker considers the future of contraception—the adaptations of existing methods, new forms of distribution, and ongoing efforts needed to support contraceptive access worldwide. Learn more about your ad choices. Visit megaphone.fm/adchoices

“Three generations of imbeciles are enough” were the infamous words U.S. Supreme Court Justice Oliver Wendell Holmes Jr. wrote in 1927. In Buck v. Bell, an almost unanimous Court upheld a Virginia law allowing the sterilization of people the state found to be “socially inadequate” and “feebleminded.” This landmark decision allowed the eugenics movement to take full effect, with multiple states passing similar laws. In Three Generations, No Imbeciles: Eugenics, the Supreme Court, and Buck v. Bell (Johns Hopkins UP, 2022), Dr. Paul Lombardo unpacks the case of an individual – Carrie Buck – to argue that the case not only represents the collective power of the eugenics movement in the early 20th century but an individual miscarriage of justice. Using extensive archival sources, Dr. Lombardo demonstrates that Carrie Buck was neither a “moral degenerate” or “feeble-minded.” She was a rape victim of sound mind. Her sterilization was based on fraudulent evidence. The powerful eugenics lobby manufactured a case – and a sympathetic court gave them a precedent that justified Carrie Buck’s sterilization – and over 60,000 sterilizations in the following decades.Three Generations, No Imbeciles frames the history of sterilization as essential to understanding contemporary legal fights over birth control and abortion. Does the constitution’s promise of “liberty” include the right to become pregnant or end a pregnancy? Dr. Lombardo’s epilogue and afterward outlines the connections between Buck and modern cases involving abortion, disability rights, and reparations for those sterilized. Originally published in 2008, the book has been updated in 2022 with a terrific epilogue and afterward with an eye towards contemporary events in reproductive politics.Dr. Paul A. Lombardo is Regents’ Professor and Bobby Lee Cook Professor of Law at the Center for Law, Health & Society at Georgia State University. He has published extensively on topics in health law, medico-legal history, and bioethics and is best known for his work on the legal history of the American eugenics movement. His website houses the images and all documents discussed in the podcast including the petition for rehearing created by the National Council of Catholic Men.Daniela Campos served as the editorial assistant for this podcast.Susan Liebell is Dirk Warren '50 Professor of Political Science at Saint Joseph’s University in Philadelphia. Learn more about your ad choices. Visit megaphone.fm/adchoices

Monica Calabritto of Hunter College talks to us today about her new book, Murder and Madness on Trial: A Tale of True Crime from Early Modern Bologna, out this year, 2023 from Penn State University Press. On October 24, 1588, Paolo Barbieri murdered his wife, Isabella Caccianemici, stabbing her to death with his sword. Later, Pablo would claim to have acted in a fit of madness--but was he criminally insane or merely pretending to be? In this riveting book, Mònica Calabritto addresses this controversy by reconstructing Paolo's life, prosecution, and medical diagnoses. Skillfully combining archival documents unearthed throughout Italy, Calabritto brings to light the case of one person and his family as insanity ravaged their financial security, honor, and reputation. The very notion of insanity is as much on trial in Paolo's case as the defendant himself. A case study in the diagnosis of insanity in the early modern era, Barbieri's story reveals discrepancies between medical and legal definitions of a person's mental state at the time of a crime. Murder and Madness on Trial bridges the micro-historical dimensions of Paolo's murder case and the macro-historical perspectives on medical and legal evidence used to identify intermittent madness. A tragic and gripping tale, Murder and Madness on Trial allows readers to look "through a glass darkly" at early modern violence, madness, criminal justice, medical and legal expertise, and the construction and circulation of news. This erudite and engaging book will appeal to early modern historians and true crime fans alike.Jana Byars is the Academic Director of Netherlands: International Perspectives on Sexuality and Gender. Learn more about your ad choices. Visit megaphone.fm/adchoices

An abolitionist approach to STS and the history of the life sciences: this is the model that Cristina Mejia Visperas offers in her book, Skin Theory: Visual Culture and the Postwar Prison Laboratory (NYU 2022). By now, scientists’ experiments on captive men at Philadelphia’s Holmesburg Prison are well known, thanks to the brave and important testimony of former captive-subjects in books like Allen Hornblum’s Acres of Skin. Building on this documentary work, Visperas turns attention to the prison experiments’ “optical rationality,” the way of seeing images that came out of a space that was simultaneously prison and laboratory. For Visperas, skin is a scientific apparatus and a metaphor for what science makes visible—and what it leaves as a void, namely, the endurance of anti-Black racism in the US, from slavery to mass incarceration. At its core, the book asks “What is the relationship between science and the project of freedom?”—and it hopes towards a reparative bioethics that dismantles scientific racism and the prison nation that it upholds.This interview was a collaborative effort among Professor Laura Stark and graduate students at Vanderbilt University in the seminar “Critical Bioethics.” Please email Laura with any feedback on the interview or questions about how to design collaborative interview projects for the classroom. Learn more about your ad choices. Visit megaphone.fm/adchoices

Freddy Foks's Participant Observers: Anthropology, Colonial Development, and the Reinvention of Society in Britain (U California Press, 2023) is a novel new history of the role of social anthropology in British society from the 1920s to the 1970s. Foks follows the anthropologist Bronislaw Malinowski and his students from the seminar room and field and out into the broader world, describing how their brand of 'social anthropology' interacted with British debates debates about colonialism, marriage and the family, and urban life. Participant Observers is especially interesting because it gives attention to Margaret Read, Elizabeth Bott, Kenneth Little, Polly Hill, and other figures whose important work has not received the attention it deserves. A clearly and at times elegantly written work, this closely researched book's ambitious scope makes it notable, and its orientation to British history gives it an unusual angle that will appeal to historians of anthropology.In this episode of the podcast, Freddy speaks with host Alex Golub about his book, the characters and events of twentieth century social anthropology, and the challenges of creating a narrative that spans several decades and an entire country.Alex Golub is associate professor of anthropology, University of Hawai‘i at Mānoa. Learn more about your ad choices. Visit megaphone.fm/adchoices

While Immanuel Kant’s account of human reason is well known and celebrated, his account of human animality (Thierheit) is virtually unknown. Animality and reason, as pillars of Kant’s vision of human nature, are original and ineradicable. And yet, the relation between them is fraught: at times tense and violent, at other times complementary, even harmonious. Kant on the Human Animal (Northwestern UP, 2022) offers the first systematic analysis of this central but neglected dimension of Kant’s philosophy. David Baumeister tracks four decades of Kant’s intellectual development, surveying works published in Kant’s lifetime along with posthumously published notes and student lecture transcripts. They show the crucial role that animality plays in many previously unconnected areas of Kant’s thought, such as his account of the human’s originally quadrupedal posture, his theory of early childhood development, and his conception of the process of human racial differentiation. Beginning with a delineation of Kant’s understanding of the commonalities and differences between humans and other animals, Baumeister focuses on the contribution of animality to Kant’s views of ethics, anthropology, human nature, and race. Placing divergent features of Kant’s thought within a unified interpretive framework, Kant on the Human Animal reveals how, for Kant, becoming human requires that animality not be eclipsed and overcome but rather disciplined and developed. What emerges is a new appreciation of Kant’s human being as the human animal it is. Learn more about your ad choices. Visit megaphone.fm/adchoices

Even people who still refuse to accept the reality of human-induced climate change would have to agree that the topic has become inescapable in the United States in recent decades. But as Joseph Giacomelli shows in Uncertain Climes: Debating Climate Change in Gilded Age America (University of Chicago Press, 2023), this is actually nothing new: as far back as Gilded Age America, climate uncertainty has infused major debates on economic growth and national development.In this ambitious examination of late-nineteenth-century understandings of climate, Giacomelli draws on the work of scientists, foresters, surveyors, and settlers to demonstrate how central the subject was to the emergence of American modernity. Amid constant concerns about volatile weather patterns and the use of natural resources, nineteenth-century Americans developed a multilayered discourse on climate and what it might mean for the nation’s future. Although climate science was still in its nascent stages during the Gilded Age, fears and hopes about climate change animated the overarching political struggles of the time, including expansion into the American West. Giacomelli makes clear that uncertainty was the common theme linking concerns about human-induced climate change with cultural worries about the sustainability of capitalist expansionism in an era remarkably similar to the United States’ unsettled present.Joseph Giacomelli is Assistant Professor of Environmental History at Duke Kunshan University.Brian Hamilton is chair of the History and Social Science Department at Deerfield Academy. Twitter. Website. Learn more about your ad choices. Visit megaphone.fm/adchoices

The Nature of Slavery: Environment and Plantation Labor in the Anglo-Atlantic World (Oxford UP, 2022) interrogates how people with an interest in African slavery manufactured and publicly disseminated a baseless rhetoric about climate, race, and labor that they knew, privately, to contradict their lived experiences.In the late eighteenth century, plantation owners and slaveholders in the Caribbean and the American South publicly argued that physiological and biological differences made African people more capable of withstanding the heat and labor required to work on plantations. This climatic defense of slavery allowed planters to deny their own culpability in enslaving human beings while also framing the issue of racial slavery. The Nature of Slavery challenges this framing of labor, environment, and the development of racial ideologies. Using extensive personal and professional correspondence and colonial records, Dr. Katherine Johnston demonstrates that privately planters did not observe any health differences between Black and white bodies. White slaveholders publicly defended racial slavery constructed on a climatic rhetoric and biological theory of race they knew to be false. The ideology linking race and climate supported the economic motives of these enslavers and this defense of racial slavery in the late 18th century became a retroactive explanation for its establishment in the colonies. This climatic dichotomy to justify slavery and their economic livelihood contributed to historical myths about enslaved bodies and a groundless theory of race which was used to perpetuate the institution of slavery. Nature of Slavery powerfully argues that a “rhetoric of bodily difference gained strength and power as slaveholders and others imbued it with a language of nature.”Dr. Katherine Johnston is an Assistant Professor in the Department of History & Philosophy at Montana State University. Her work focuses on slavery, race, the body, and the environment in Atlantic plantation societies.Daniela Lavergne served as the editorial assistant for this podcast.Susan Liebell is Dirk Warren '50 Professor of Political Science at Saint Joseph’s University in Philadelphia. Learn more about your ad choices. Visit megaphone.fm/adchoices

Mike Jay's Psychonauts: Drugs and the Making of the Modern Mind (Yale UP, 2023) is a provocative and original history of the scientists and writers, artists and philosophers who took drugs to explore the hidden regions of the mind.Until the twentieth century, scientists investigating the effects of drugs on the mind did so by experimenting on themselves. Vivid descriptions of drug experiences sparked insights across the mind sciences, pharmacology, medicine, and philosophy. Accounts in journals and literary fiction inspired a fascinated public to make their own experiments--in scientific demonstrations, on exotic travels, at literary salons, and in occult rituals. But after 1900 drugs were increasingly viewed as a social problem, and the long tradition of self-experimentation began to disappear. From Sigmund Freud's experiments with cocaine to William James's epiphany on nitrous oxide, Mike Jay brilliantly recovers a lost intellectual tradition of drug-taking that fed the birth of psychology, the discovery of the unconscious, and the emergence of modernism. Today, as we embrace novel cognitive enhancers and psychedelics, the experiments of the original psychonauts reveal the deep influence of mind-altering drugs on Western science, philosophy, and culture.Claire Clark is a medical educator, historian of medicine, and associate professor in the University of Kentucky’s College of Medicine. Learn more about your ad choices. Visit megaphone.fm/adchoices