The Mind Killer

This is a free preview of a paid episode. To hear more, visit mindkiller.substack.comBonus episode featuring an interview with Jorge, the so-called “mayor of Próspera.”

Wes, Eneasz, and David keep the rationalist community informed about what’s going on outside of the rationalist communitySupport us on Substack!News discussed:DEA ruins telemedicineTrump is already selling mug shotsThe liberals won the Wisconsin Supreme Court seatSenate voted to repeal 2002 AUMFMcCarthy says House will probably pass it, but it has to go through committeeNationwide injunction on abortion pills, but also the opposite of thatBiggest intelligence leak since SnowdenFirst appeared on a tiny meme-Discord 5 weeks agoReboot/NoFap appears to make followers *worse*Doocy asks about AI Doom at White House press briefingLLMs can greatly compress prompts for future self-decoding (but lossy)Chatbot convinces Belgian to commit suicideAI village of 25 NPCs created. Amazing resultsHappy News!New Nuclear plant plugged into the gridDrs Feng Zhang and Joe Kreitz created a molecular delivery system that can deliver proteins only to specific types of cellsProfessor Gilad Yossifon created microrobots that can navigate between cells, and identify and capture individual cellsNow CRISPR RNA is delivered to the mouse lung by inhalation using improved lipid nanoparticlesPaves the way for therapeutic CRISPR applications in the lung, including possibly cystic fibrosis!Some Coastal Salt Marshes Are Keeping Up With Sea Level RiseFDA stops preventing people from buying a life-saving drug!Blast your heart with your own stem cells to reduce inflammation, risk of heart attack and stroke!Utah and California Snowpacks Break All Previous Record. “cautiously optimistic” “Drought is expected to improve further or go away completely across much of California.”.Got something to say? Come chat with us on the Bayesian Conspiracy Discord or email us at themindkillerpodcast@gmail.com. Say something smart and we’ll mention you on the next show!Follow us!RSS: http://feeds.feedburner.com/themindkillerGoogle: https://play.google.com/music/listen#/ps/Iqs7r7t6cdxw465zdulvwikhekmPocket Casts: https://pca.st/vvcmifu6 Stitcher: https://www.stitcher.com/podcast/the-mind-killer Apple: Intro/outro music: On Sale by Golden Duck Orchestra This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit mindkiller.substack.com/subscribe

Wes, Eneasz, and David discuss the news from the last two weeks from a rationalist perspectiveSupport us on Substack!News discussed:Credit Suisse collapsed and bought by UBSRESTRICT Act seems like a big Executive power grabUtah is building a registry of all residents that use social media. RIP DavidAlso requires parental consent for anyone under 18 to be on, and gives parents full access to children’s accounts Biden vetoed anti woke capital resolutionNew executive order on gunsNRA says it’s announcing “a general principle that federal agencies should use whatever authorities they have to make life more difficult for gun owners or the businesses that serve them”Trump threatened “potential death and destruction” if he’s criminally chargedARC tested GPT4 capabilities, including prompting it to try to break out and replicate.ChatGPT Plugins let it browse the web, do stuff for youText-only GPT-4 learned what things look like and can draw them Meta made a model 95% as good as ChatGPT, that is small enough to run on your phoneEternal ChildrenLlamas with Hats!Happy News!GPT4 saved a dog’s life by accurately diagnosing it after being given symptomsFTC voted 3-1 to introduce "click to cancel," to easy subscription cancellations.stretchable bandage that accelerates healing by delivering electrotherapy directly to the wound speeds healing by 30%. the components that interface with the wound are entirely resorbableLies about Chris Avelone dismissed with prejudice in libel suit, awarded over $1M, and the perps have made public renunciations of their lies.retinitis pigmentosa affects 1 in 4000, causes blindness, cured by CRISPRGot something to say? Come chat with us on the Bayesian Conspiracy Discord or email us at themindkillerpodcast@gmail.com. Say something smart and we’ll mention you on the next show!Follow us!RSS: http://feeds.feedburner.com/themindkillerGoogle: https://play.google.com/music/listen#/ps/Iqs7r7t6cdxw465zdulvwikhekmPocket Casts: https://pca.st/vvcmifu6 Stitcher: https://www.stitcher.com/podcast/the-mind-killer Apple: Intro/outro music: On Sale by Golden Duck Orchestra This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit mindkiller.substack.com/subscribe

Wes, Eneasz, and David discuss the news from the last two weeks from a rationalist perspectiveSupport us on Substack!News discussed:S**t is going down in IsraelBig protests over Netanyahu’s proposed judicial reformsNew proposals would give political appointees a majorityElite fighter squadron is boycotting trainingSilicon Valley Bank is insolventJacob Falkovich blames the governmentBank run stopped by new Fed policy the Bank Term Funding ProgramAnthropic Shadow? “this is what it would look like if you wanted to stifle innovative sectors”In Nebraska a mom & daughter will stand trial for abortionThe American Association of Pediatric released new guidelines for childhood obesityEating disorder experts are not happyFTC is going after MuskFTC is unhappy about “twitter files” exposing this, demands list of journalists from twitter, issues finesFTC commissioner resigns, cites FTC Chairman’s “disregard for the rule of law and due process,” and “abuses of government power,” Partisan rift forming around FTC? Republicans investigating the investigation!AlphaFold2 continues to do lots of stuffGPT-4 coming in the next week or soYou can’t stop AI progressHappy News!Toddler vaccinations are up!The asteroid diversion was a success!Growing Nuclear Acceptance! Start-up Sakuu uses 3D printers to print solid-state batteriesGot something to say? Come chat with us on the Bayesian Conspiracy Discord or email us at themindkillerpodcast@gmail.com. Say something smart and we’ll mention you on the next show!Follow us!RSS: http://feeds.feedburner.com/themindkillerGoogle: https://play.google.com/music/listen#/ps/Iqs7r7t6cdxw465zdulvwikhekmPocket Casts: https://pca.st/vvcmifu6 Stitcher: https://www.stitcher.com/podcast/the-mind-killer Apple: Intro/outro music: On Sale by Golden Duck Orchestra This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit mindkiller.substack.com/subscribe

Wes, Eneasz, and David discuss the news from the last two weeks from a rationalist perspectiveSupport us on Substack!News discussed:A pretty good open-source LLM with a webapp interface has been releasedIran Followup - young couple give (combined) 10year jail sentence for dancing in public (and filming it)Iran’s Revolutionary Guard increasingly deployed in protest crack-downs.East Palestine, Ohio local police department declares unrestricted chemical warfare on OhioSummaryOn-the-ground footageMoreReporters trying to find out what the heck happened getting arrestedTurkey hit with 7.8 & 7.5 mag earthquakes. 35K dead. Reports that building codes were waived for years partly responsible. Jobs for everyone!H5N1 can/has spread to mammalsOpenAI released an AI safety policy proposal. It sucks unbelievable quantities of ass.Getty Images suing Stable Diffusing for 1.8 TrillionThe eighth seal of the apocalypse has broken, and the deepfake boner pill scams have poured forth to cover the EarthA judge in Colombia used ChatGPT to make a court rulingDemocrats made South Carolina the first primary instead of IowaNew Hampshire is not playing ballCovid is over… on May 11thHappy News!California nuked its zoning codeDevelopers are sharing creative ideasIndia discovers 5.9m tonnes of Lithium!Only 13 human cases of Guinea worm disease in 2022SpaceX successfully static-fire tests StarshipA new way to significantly increase the potency of almost any vaccine has been developed by International Institute for Nanotechnology (IIN) at Northwestern University. The paper is here.Brain Cancer Vaccine being developedGot something to say? Come chat with us on the Bayesian Conspiracy Discord or email us at themindkillerpodcast@gmail.com. Say something smart and we’ll mention you on the next show!Follow us!RSS: http://feeds.feedburner.com/themindkillerGoogle: https://play.google.com/music/listen#/ps/Iqs7r7t6cdxw465zdulvwikhekmPocket Casts: https://pca.st/vvcmifu6 Stitcher: https://www.stitcher.com/podcast/the-mind-killer Apple: Intro/outro music: On Sale by Golden Duck Orchestra This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit mindkiller.substack.com/subscribe

Wes, Eneasz, and David keep the rationalist community informed about things going on outside of the rationalist communitySupport us on Substack!News discussed:Bounded distrustThe SCOTUS leak investigation fizzled outClassified documents also found at Mike Pence’s house!Eight in 10 people in China caught Covid since early December, say officialsIsrael strikes Iranian drone plant with their own drone strikeNATO countries sending Leopard 2 main battle tanks to Ukraine, US sending Abrams 1 Russia pushing into Donetsk, striking before tanks arriveHuge increase in homicides is persistingTyr Nicoles beat to death by police earlier this monthGas stoves became the main character of the internet for some reasonF**k that noise (Zvi)Trump indictment decisions are “imminent” in Georgia election interference caseConversely, New York chickenshit prosecutors failed to charge in Stormy Daniels case“class action” copyright lawsuit filed against Stability AI, DeviantArt, and Midjourney related to Stable Diffusion.Apparently it’s b******tReal estate agents using ChatGPT commerciallyAfter CA votes to keep Diablo Canyon nuclear power plant in operation, NRC says “nah”Some auto insurers are refusing to cover certain Hyundai and Kia modelsHappy News!(fake happy news) China considers banning export of solar panel componentsClimeworks pulled CO2 from the air stored it undergroundResearch on pain-insensitivity gene continues.Endangered Species Act has saved hundreds from extinctionArtificial Pancreas looks to be twice as good as normal insulin injectionTroop Deployment LinksJon Stokes’ and Construction Physics substacks are quite good. David recommends this piece on the Stability lawsuit And this piece on why automatic bricklayers don’t exist.Got something to say? Come chat with us on the Bayesian Conspiracy Discord or email us at themindkillerpodcast@gmail.com. Say something smart and we’ll mention you on the next show!Follow us!RSS: http://feeds.feedburner.com/themindkillerGoogle: https://play.google.com/music/listen#/ps/Iqs7r7t6cdxw465zdulvwikhekmPocket Casts: https://pca.st/vvcmifu6 Stitcher: https://www.stitcher.com/podcast/the-mind-killer Apple: Intro/outro music: On Sale by Golden Duck Orchestra This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit mindkiller.substack.com/subscribe

Wes, Eneasz, and David discuss the news from the last two weeks from a rationalist perspective, with special guests appearances by Charlie and Gray!Support us on Substack!News discussed:The Electoral Count Reform Act was passedFinally got enough on the 15th ballotMexico captures El Chapo’s son (again) and has a literal military battle with cartels. Brazil’s Jan 6th happened on Jan 8th.By one estimate, the US has sent close to 1/5th of our artillery shell stockpile to Ukraine, which will take 2yrs to replenish at current ratesLanguage Models can make completely de novo proteins that are viable in the wetlab. William Eden has the best take.LLMs can discern cause & effectWhen Google tuned a AI chatbot to answer common medical questions, doctors judged 92.6% of its answers rightIt also passed the Official medical examBraced pistols now regulated under same rules as SBRsSexy News Update - more than 75% of casual sex isn’t ONS, it’s an extended sexual relationship with a friend/acquaintance. Ecuadorian man changes gender to route around sexist lawsHappy News!South Carolina court found right to abortion in Constitution up to 20 weeksFDA lifted rule banning mifepristone (abortion pill) from being sold in pharmaciesTom Lehrer put all of his music in the public domainThe End Poem of Minecraft is too!FTC is (probably) banning non-compete clauses!!Counterpoint from Tyler CowenJapan is NukeMaxxing!DUKE NUCLEAR!In big New Atheist win, Congressman Was Sworn Into Office With Rare Superman ComicEneasz crossed a bridgeGot something to say? Come chat with us on the Bayesian Conspiracy Discord or email us at themindkillerpodcast@gmail.com. Say something smart and we’ll mention you on the next show!Follow us!RSS: http://feeds.feedburner.com/themindkillerGoogle: https://play.google.com/music/listen#/ps/Iqs7r7t6cdxw465zdulvwikhekmPocket Casts: https://pca.st/vvcmifu6 Stitcher: https://www.stitcher.com/podcast/the-mind-killer Apple: Intro/outro music: On Sale by Golden Duck Orchestra This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit mindkiller.substack.com/subscribe

Wes and David discuss the news from the last two weeks from a rationalist perspective WITHOUT Eneasz for onceSupport us on Substack!News discussed:California court declared that anything good violates CEQAGeorge Santos (R-NY) is a big fat phonySpencer Greenberg podcast featuring Elizabeth Edwards-AppellNY “Right to Repair” law passed but made uselessa bunch of standard cell lines are THE WRONG CELLS (h/t Sarah Constantin)Happy News!Colorado decriminalization DMT, psilocybin, mescaline, and iboganeResearchers deactivated the BRD8 protein that’s key to this cancer using a pioneering gene editing technique. stopped the tumor growth in its tracks27-year-old Jay Withey saved the lives of two dozen people during the deadly storm by rescuing strangers from cars trapped in the snow and bringing them into a school for shelter.Got something to say? Come chat with us on the Bayesian Conspiracy Discord or email us at themindkillerpodcast@gmail.com. Say something smart and we’ll mention you on the next show!Follow us!RSS: http://feeds.feedburner.com/themindkillerGoogle: https://play.google.com/music/listen#/ps/Iqs7r7t6cdxw465zdulvwikhekmPocket Casts: https://pca.st/vvcmifu6 Stitcher: https://www.stitcher.com/podcast/the-mind-killer Apple: Intro/outro music: On Sale by Golden Duck Orchestra This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit mindkiller.substack.com/subscribe

Show notes:Wes, Eneasz, and David discuss the news from the last two weeks from a rationalist perspectiveSupport us on Substack!News discussed:Kirsten Synema left the Democratic Party. MAVERICK!Jan. 6th committee referred Trump for chargesTrump Org found guilty of tax fraudProspera sues Honduras for approximately 30% of its GDPSBF arrested and indicted bad news for school emancipation the Islamic Republic of Iran was just expelled from the U.N. Women's Rights Commission.China reverses covid policyHappy News!Net-gain in fusion power breakthrough, kinda-sortaEdit T-cell genomes (not gnomes) for great cancer-busting justice!Organ-on-chips allow for direct drug testing on human tissueEneasz on his first rationalist solsticeGot something to say? Come chat with us on the Bayesian Conspiracy Discord or email us at themindkillerpodcast@gmail.com. Say something smart and we’ll mention you on the next show!Follow us!RSS: http://feeds.feedburner.com/themindkillerGoogle: https://play.google.com/music/listen#/ps/Iqs7r7t6cdxw465zdulvwikhekmPocket Casts: https://pca.st/vvcmifu6 Stitcher: https://www.stitcher.com/podcast/the-mind-killer Apple: Intro/outro music: On Sale by Golden Duck Orchestra This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit mindkiller.substack.com/subscribe

Wes, Eneasz, and David discuss the news from the last two weeks from a rationalist perspectiveSupport us on Substack!News discussed:A top Iranian official has said that the nation’s mandatory hijab law is being reviewedSpecial counsel appointed to investigate TrumpAnother round of China protests over Covid lockdownsSparked by fire in a locked-down apt, possibly extra harsh due to being Uyghur neighborhood/building Definitely unrelated to anything else going on, Jiang Zemin diedNATO allies capping Russian Oil at $60/barrel? “In essence, such a decree would ban the export of oil and petroleum products to countries and companies that apply it.” (Doesn’t apply to pipelines, yet) covers more than two-thirds of Russian oil imports coming into the EU. India, China and Turkey not affected. US Strategic Petroleum Reserve at record lows, down 1/3rd from a year agoCicero in top 10% of Diplomacy players. (more)ChatGPT can do anything, including modeling itself in an imaginary internet, or describe how to take over the world. Does slightly worse than average human on SAT, and it’s retarded.Advent of Code competition is being won by GPTCarperAI released OpenELM, an open-source large language model AI superpowers - can tell race via chest Xray. Can tell sex via retina scan (87%)Twitter Files confirm what we knew - Hunter Biden laptop is real, DNC has direct access to Twitter’s censors, asked for it to be censored, request granted. Seems if this is a big deal or not depends on how you feel about govt suppression of this story.Core inflation down to 2.7%Wikipedia influences the lawFormer anti-abortion leader claims Justice Alito leaked Hobby Lobby decisionA 32 year old woman is trying to sue the doctors that did the surgery she requestedHappy News!A woman who has a concealed carry license took on four armed men who tried to carjack herWe developed a new multivalent mRNA vaccine against all known influenza virus subtypes.After each game, Japanese WorldCup fans pick up litter. 900 megawatt “water battery” with a storage capacity of 20 million kilowatt hours debuts in Switzerland next weekCAR T-Cell Therapy Sends Lupus into RemissionNew farm robot can specifically target individual weeds and cropsGot something to say? Come chat with us on the Bayesian Conspiracy Discord or email us at themindkillerpodcast@gmail.com. Say something smart and we’ll mention you on the next show!Follow us!RSS: http://feeds.feedburner.com/themindkillerGoogle: https://play.google.com/music/listen#/ps/Iqs7r7t6cdxw465zdulvwikhekmPocket Casts: https://pca.st/vvcmifu6 Stitcher: https://www.stitcher.com/podcast/the-mind-killer Apple: Intro/outro music: On Sale by Golden Duck Orchestra This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit mindkiller.substack.com/subscribe