News Anchor and Author Chris Hayes joins Andy to discuss growing up in a diverse neighborhood, wanting to be an actor and director before becoming a reporter, and the showbiz of the news.

Actor and Comedian Hannah Einbinder (Hacks on HBO Max) joins Andy to discuss growing up in LA, wanting to be a journalist before getting into comedy, living with ADHD, and more.

Andy revisits some of his favorite moments on the podcast to celebrate the 100th episode. This week's episode features Maria Bamford, Will Arnett, Deon Cole, Zach Galifianakis, Nicole Byer, and Scott Thompson.

Actor and comedian Tim Meadows joins Andy to discuss their shared Chicago roots, the challenges of being a divorced dad, and how Talking Heads inspired his comedy career. Plus, Tim remembers and reflects on his friend Chris Farley.

Author Lauren Hough calls her Twitter pal Andy to talk about her new book, "Leaving Isn't The Hardest Thing." They also discuss her experiences growing up in a cult, being gay in the military during peak "Don't ask, don't tell," and the power of empathy.

Late-night talk show host Jimmy Kimmel joins Andy to discuss his childhood in Las Vegas, how he made the jump from radio to TV, and why his family is such a big part of his show and his success.

Singer-songwriter Liz Phair joins Andy to talk about her new album "Soberish." She also reflects on her life straddling two states, her background as a visual artist, and what it takes to be a rockstar.

Actress Judy Greer catches up with her friend Andy. Judy shares the perks of playing the sidekick, how she stumbled into an intense acting conservatory, and some sage advice from Dido.

Actor and comedian JB Smoove joins Andy to drop some jewels of wisdom. The two discuss how JB got the standup bug, his affinity for giving advice, and why he loves being a work in progress. Plus, JB breaks down his new podcast "May I Elaborate?" which debuted April 26th.

Actress and comedian Sasheer Zamata joins Andy to discuss her origins in Okinawa and Indiana, why stage fright never fazed her, and possibly the world's worst therapist. Sasheer also talks about her role in the new show Home Economics.