The Peter Attia Drive

Layne Norton, Ph.D., is a nutrition expert, physique coach, and natural bodybuilder. He dives into powerful training principles suitable for all fitness levels and shares insights from his powerlifting career. Topics include the benefits of creatine supplementation, evolving views on nutrition, and how strength training enhances longevity. Layne discusses common nutrition myths, the importance of dietary flexibility, and strategies for effective weight management, emphasizing the balance between enjoying exercise and achieving goals.

Chris Hemsworth, renowned for his role as Thor, shares insights from his journey in the docuseries Limitless. He recalls extreme challenges like a four-day fast and arctic swims, revealing how these experiences reshaped his views on health and happiness. Hemsworth discusses the role of genetics in health risks, particularly Alzheimer's, and shares the benefits of practices like sauna use and ice baths for overall wellness. He also reflects on embracing mortality and the importance of balancing work with personal fulfillment.

Discover effective tips for optimizing your sleep routine! The discussion covers pre-bedtime practices, including a beneficial sauna regimen. Dive into the world of sleep-enhancing medications and supplements while learning about their mechanisms and potential risks. The conversation also explores the pros and cons of sleep tracking wearables. Emphasizing the importance of minimizing stimulation before bed, this episode offers valuable insights for anyone looking to improve their sleep quality.

Orthopedic surgeon Alton Barron, founder of the Musician Treatment Foundation, shares his expertise on upper extremity health. He delves into common injuries like rotator cuff tears and frozen shoulder, discussing both non-surgical and surgical treatment options. Alton highlights the importance of physical exams in diagnosis, the evolution of orthopedic techniques, and how anatomical variations can lead to injuries. He also addresses the unique health challenges faced by musicians and the vital role of funding for specialized care.

Gerald Shulman, a Yale Professor and Director of the Diabetes Research Center, shares his expertise on insulin resistance and its implications for health. He dives into mechanisms affecting muscle and liver function, the evolutionary role of insulin resistance, and how lifestyle factors like diet and exercise play a significant part. Shulman also highlights the effectiveness of Metformin, linking its action to longevity, while explaining the alarming connections between lipid accumulation and metabolic health.

The host delves into the evolution of medicine, highlighting a promising shift towards Medicine 3.0, focused on prevention and personalized care. Listeners hear about the host's unique career path and his approach to risk assessment in healthcare decisions. Insights into prioritizing health during stressful times are shared, along with exciting breakthroughs in aging and longevity. A rapid-fire segment offers tips on cold plunging, managing apoB levels, and designing beginner exercise programs, making health and longevity accessible to all.

In this engaging discussion, Dr. Erin Michos, a renowned preventive cardiologist at Johns Hopkins, dives deep into the rising threat of cardiovascular disease in women. She highlights how unique factors like pregnancy and menopause influence risk and emphasizes the critical need for early preventative measures. Dr. Michos explains the importance of managing LDL-cholesterol and the role of new treatments like GLP-1 agonists and PCSK9 inhibitors. Listeners also gain insights into the gender-specific nuances of heart health and practical lifestyle changes to reduce risks.

Allan Sniderman, a leading expert in lipoprotein metabolism, and Tom Dayspring, a specialist in atherosclerotic cardiovascular disease (ASCVD), share their insights on cardiovascular health. They discuss the limitations of standard lipid metrics and highlight apoB as a superior risk assessment tool. The conversation dives into the importance of early intervention and challenges misconceptions around cholesterol, advocating for proactive measures against ASCVD. Discover how understanding these factors can significantly alter prevention strategies.

Holly Baxter, an accredited practicing dietician and competitive bodybuilder, shares her journey through mental health struggles and eating disorders. She discusses her road to recovery, emphasizing the importance of therapy and self-compassion. Holly also outlines female-specific training principles, effective nutrition strategies for muscle gain, and the concept of reverse dieting. Her insights provide a roadmap for women seeking to improve their physique while prioritizing mental well-being and realistic goals in fitness.

Discover the secrets of body composition as Peter explains how to interpret DEXA scan results, revealing metrics like lean muscle mass and bone density. Get insights into dietary protein needs and the optimal timing for intake to maximize muscle growth. Explore the benefits of time-restricted feeding and fasting, alongside evolving personal recommendations. Real patient case studies illustrate these concepts, shedding light on practical applications for improved health.