
Curious Cases
Hannah Fry and Dara Ó Briain tackle listeners' conundrums with the power of science!
Latest episodes

Dec 8, 2021 • 28min
Rutherford and Fry on Living with AI: AI in Warfare
What if a despotic leader could programme a swarm of drones to kill a set of identified targets with just the push of a button? Due to ever expanding AI capabilities this extreme dystopian vision may not be technically unfeasible. In this second of a four part series responding to this year's BBC Reith lectures from Stuart Russell, Adam Rutherford and Hannah Fry unpick the role of AI in warfare.Joining them to help them navigate the battlefield of information is Ulrike Franke, a senior policy fellow at the European Council on Foreign Relations who specialises in the future of warfare.Together they will be investigating 'lethal autonomous weapons' - these are weapons that can find, chose and kill human targets without human supervision. We will be discussing how advanced this technology actually is - some think the world may have already experienced the first ever autonomous strike in Libya. What are the repercussions of this technology for safety on the battlefield , and what are the wider geo-political ramifications?Stuart Russell has deep concerns over the development of these types of weapons and Rutherford and Fry pick apart some of the ethical debates this technology raises. Who would be responsible if a system malfunctioned and killed a civilian? What's to stop it getting into the wrong hands? Should we even be creating these weapons in the first place - do we instead need a convention banning them? And is that even possible?

Dec 1, 2021 • 28min
Rutherford and Fry on Living with AI: The Biggest Event in Human History
Artificial Intelligence (AI) is already ubiquitous in our lives. It curates our nightly TV entertainment, connects us to our friends online and navigates us, mostly successfully, to our destinations. However these uses are just the beginning, and it will likely bring societal changes we can’t yet imagine.In this year’s BBC Reith lectures, AI expert Professor Stuart Russell will be exploring how AI has been represented in popular fiction, envisaging how this technology might shape our futures and how we best prepare for it. So who better to unwrap his ideas than science sleuths Adam Rutherford and Hannah Fry, with their customary curiosity and irreverent insights?In this, the first of four episodes, Rutherford and Fry – together with guests author and podcaster Azeem Azhar and AI scholar Kate Crawford - will be unravelling what we actually mean by AI, exploring how far machine learning already underpins our lives, imagining the functions it might provide in the future and asking what challenges and risks might lie ahead. Can AI transform society as profoundly as electricity once did leading to a golden age for humanity, or have we all watched too many sci-fi movies?

Nov 11, 2021 • 43min
The Venomous Vendetta
Whilst watching a documentary about some poisonous frogs, Curio Janni in Amsterdam, started to wonder what would happen if a frog licked itself or another frog of the same species. She asks Dr Adam Rutherford and Professor Hannah Fry to investigate whether an animal would react badly to a toxin it itself produces? In essence 'can a venomous snake kill itself by biting itself?'Of course the answer is complicated, but the sleuths know exactly who to ask.Steve Backshall, award-winning wildlife explorer, best known for his BBC series 'Deadly 60'. Author of 'Venom – Poisonous Creatures in the Natural World'. Steve has been bitten, stung and spat at by a plethora of venomous creatures during his career. He also studied the first known venomous newt - the sharp-ribbed newt - a creature that has sharpened ribs that when it's under attack, it will squeeze its body force those ribs out through its skin, coating them in venom, which is then delivered into the mouth of an attacker. Professor Nick Casewell, studies venomous snakes and their impact on humans. He works on treatments for snakebites at the Liverpool School of Hygiene and Tropical Medicine. Snakebites have a huge impact on communities in South Asia, Sub-Saharan Africa and South America. It's now been reinstated as one of the most serious neglected tropical diseases by the World Health Organisation. Traditional treatments - antivenins - can be expensive, difficult to access and don't always work - Nick is looking into alternative medicines to treat snakebite victims.Dr. Ronald Jenner is Principal Researcher in the Comparative Venomics group at the Natural History Museum's Life Sciences, Invertebrates Division and co-wrote the book ‘Venom -the secrets of nature's deadliest weapon.’ He explains the evolutionary arms race between venomous predators and their prey and poisonous prey and their predators. He explains how resistance to venom has evolved and how venom has evolved to be more or less powerful over time, answering another Curio - Scott Probert's question on the evolution of venom.Christie Wilcox wrote 'Venomous – How Earth’s Deadliest Creatures Mastered Biochemistry'. She studied the molecular basis of lionfish venom. Christie describes how venom and immunity to venom works at the molecular level.Presenters: Adam Rutherford and Hannah Fry Producer: Fiona RobertsFirst broadcast on BBC Radio 4 in November 2021.

Nov 4, 2021 • 38min
The Slippery Situation
'What is the slipperiest thing in the world?' asks 8 year old Evelyn. Why do my feet slip on a wet floor but when my feet are even slightly moist it's nearly impossible to put on a pair of socks without falling over and cursing the universe. What is going on here?' asks Evelyn's Dad, Sam.Hannah and Adam investigate the science of friction and lubrication - so called 'tribology' with the help of tribologists and mechanical engineers Professor Ashlie Martini from California University Merced and Professor Roger Lewis from the University of Sheffield. With their help Hannah and Adam find out why leaves on the line are so slippery, what happens to graphite in space and what is the slipperiest food. Professor of Materials, Mark Miodownik from University College London explains what's going on when friction stops two materials sliding past each other and wonders whether the slipperiest substance was actually discovered accidentally in a lab by scientists looking for something completely different. Also in the programme why the ability to reduce friction, even by minuscule amounts could have a huge impact for sustainability and reducing energy use. Producers: Jen Whyntie and Pamela RutherfordFirst broadcast on BBC Radio 4 in November 2021.

Oct 28, 2021 • 37min
The Painless Heart
Why does my heart not ache after exercise? asks listener Keith. Rutherford and Fry explore how and why heart muscle cells are special.Dr Mitch Lomax is a sports scientist at the University of Portsmouth. She helps actual Olympic swimmers get faster. She explains how most of the muscles attached to our skeletons work: Tiny fibres use small-scale cellular energy, which, when all these fibres work in concert, turns into visible muscular movement. Mitch also explains how the dreaded Delayed Onset Muscle Soreness, or DOMS, can hit, taking a stair-wincing 48-72 hours to peak after exercise.But skeletal muscles turn out to be quite different to heart muscles, as consultant cardiologist Dr Rohin Francis explains. Heart cells are more efficient and don't get fatigued like skeletal muscle cells. They are extremely energetic and 'just want to beat'. He also explains that the sensory feedback from the heart muscles is different too. They have a different sort of nerve supply, with fewer sensory nerves, so that there is less chance of pain signals being sent to the brain.However, heart cells' incredible abilities are counterbalanced by one Achilles-like flaw: They cannot easily heal. Professor Sanjay Sinha is a British Heart Foundation (BHF) Senior Research Fellow and a Professor in Cardiovascular Regenerative Medicine at the University of Cambridge. His job is to fix broken hearts and he explains to Adam how new research into stem cells could be used to fix normally irreparable heart cells.Presenters: Hannah Fry and Adam RutherfordProducers: Jennifer Whyntie and Fiona RobertsFirst broadcast on BBC Radio 4 in October 2021.

Oct 21, 2021 • 40min
The Weirdness of Water Part 2/2
“I don’t really understand why water has so many properties on different scales ranging from very large and cosmic to very small quantum and quarky - Could you help by zooming in and out on water to explain what is known about it? "Asks Neil Morton in Stirling. “Why does boiling water sound different to cold water?’ asks Barbara Dyson in Brittany in FranceOllie Gordon, in Christchurch in New Zealand, wants to know ‘why water is essential for all life as we know it?’And many more questions on the weirdness of water are tackled by super science sleuths Hannah Fry and Adam Rutherford. With assistance from: * Quantum physicist Professor Patricia Hunt, at the Victoria University in Wellington in New Zealand* Science writer and author of ‘H2O – a biography of water’ Philip Ball* Physicist and bubble expert in the Department of Mechanical Engineering at UCL, Dr Helen Czerski.Producer: Fiona RobertsFirst broadcast on BBC Radio 4 in October 2021.

Oct 14, 2021 • 37min
The Weirdness of Water Part 1/2
“I don’t really understand why water has so many properties on different scales ranging from very large and cosmic to very small quantum and quarky - Could you help by zooming in and out on water to explain what is known about it?" asks Neil Morton in Stirling. Rutherford and Fry learn about the special hydrogen bonds that makes water such an unusual liquid.Quantum physicist Professor Patricia Hunt, at the Victoria University in Wellington in New Zealand explains to Hannah the quantum properties of individual water molecules and how they link up with other water molecules in liquid water and solid ice. She describes the hydrogen bonds that give water some of it’s weird and wonderful properties such as why ice floats, why water is able to store huge amounts of heat and why water has such a strong surface tension.Science writer and author of ‘H2O – a biography of water’ Philip Ball describes how in the 18th century it was discovered that water was not one of the classical elements, but a compound liquid of water and hydrogen and explains to Adam why there are at least 15 different types of ice.Physicist Dr. Helen Czerski sets the record straight on how ice forms in oceans and lakes and why water is at its densest at 4 degrees Centigrade and not zero.Presenters: Hannah Fry & Adam RutherfordProducer: Fiona RobertsFirst broadcast on BBC Radio 4 in October 2021.

Oct 7, 2021 • 39min
The Guiding Hound
How do guide dogs know where they're going? It's not like their handler whispers in their ear and asks to go to the pharmacy, maybe the toothpaste aisle. So how does it work? asks Charlotte, aged 42. Dogs and humans have gone paw in hand for thousands of years. Historic and genetic evidence shows we’ve shaped each other's existence over millennia. But dogs were only first trained as guides for blind people in the UK 90 years ago. What’s the biology behind this extraordinary partnership? Hannah heads to Guide Dogs UK’s training school in Royal Leamington Spa. She meets up with expert Graham Kensett to find out what it takes to make a guide dog from nose to tail, starting from before birth and following the life course through to retirement. Hannah also meets the delightful Wendy and Wilmott, a German shepherd and a retriever cross. Despite both still growing into their ears, they show her their already extraordinary skill set, from tackling obstacle courses to safely crossing roads. Cool, calm, patient, unflappable: Guide dogs are the astronauts of the canine world. But, as trainer Jenna explains, it’s all in the partnership with the owner, who needs to do plenty of work in terms of training and learning routes to journey in harmony with their furry guide.Richard Lane has owned guide dogs for over 25 years, and confirms this first hand. He reveals just how he gets to the toothpaste aisle, and tells Adam how at its peak a partnership can navigate London Waterloo station better than some sighted people, even at rush hour. Richard also explains how deeply felt the bond that forms between owner and dog is, and describes the hardest part of guide dog ownership: Letting go at the end. Presenters: Hannah Fry & Adam Rutherford
Producer: Jen WhyntieA BBC Audio Science Unit production for BBC Radio 4

Feb 23, 2021 • 29min
More Frytful Scares
It was a dark and stormy night. A secret message arrived addressed to Rutherford & Fry from a mysterious woman called Heidi Daugh, who demanded to know: "Why do people like to be scared? For example, going on scary amusement park rides and watching horror movies that make you jump.”What followed was an investigation, which would test our intrepid duo to their very limits. They explore the history of horror, starting with its literary origins in the Gothic fiction classic 'The Castle of Otranto'.Adam challenges Hannah to watch a horror film without hiding behind a cushion. She quizzes horror scholar Mathias Clasen to find out why some people love the feeling of terror, whilst it leaves other cold.Sociologist Margee Kerr and psychologist Claudia Hammond are also on hand to explore why scary movies are so powerful and popular.
Then Rutherford and Fry investigate the more physical side of fear, when they delve into the history of roller coasters to investigate why we enjoy being scared.Never ones to shy away from a challenge, the pair attempt to channel their inner adrenaline junkies with a trip on one the UK's scariest roller coasters at Thorpe Park.David Poeppel from New York University studies the science of screaming, and we discover what makes screams uniquely terrifying. Plus, psychologist and broadcaster Claudia Hammond describes some early experiments which tested how fear affects our body.This episode is a remake of two earlier broadcast episodes.Producers: Fiona Roberts & Michelle Martin Presenter: Adam Rutherford & Hannah FryFirst broadcast on BBC Radio 4 in February 2021.

Feb 16, 2021 • 30min
Back to The Sinister Hand
Why are some people left-handed, whereas the majority are right handed? Rutherford and Fry revisit The Sinister Hand episodes to further investigate handedness in humans and animals. They considered cockatoos, chimpanzees and Hannah's dog, Molly, to discover that humans are unique, with just one in ten of us being left-handed.They ask if there is an evolutionary reason for just 10% of the human population being southpawsHannah talks to primatologist Prof Linda Marchant from Miami University about Neanderthal teeth and termite fishing.Adam consults handedness expert Prof Chris McManus from University College London. He's been trying to track down the genes responsible for whether we're right or left handed.And what about left-handed brains or eyes or molecules?Prof Andrea Sella explains handedness, or chirality, at the molecular scale and why when we consider Thalidomide, something seemingly so trivial can be extremely important.They also explore the left-handed brain. Some researchers point to a link between left-handedness and impairments like autism or dyslexia. Others claim that lefties are more creative and artistic.So what's the truth? The team consults Professors Sophie Scott, Chris McManus and Dorothy Bishop to find out.This episode is an updated version of two earlier broadcast episodes.If you have any Curious Cases for the team to investigate please email curiouscases@bbc.co.ukProducers: Fiona Roberts & Michelle MartinPresenter: Adam Rutherford & Hannah FryA BBC Audio Science Unit production for BBC Radio 4, first broadcast in 2021.