

Talking Precision Medicine
Genialis
Welcome to the Talking Precision Medicine podcast. In this series, we sit down with experts on the application of AI and big data analytics in the drug discovery space. Our guests are innovators, business decision makers and thought leaders at the intersection of data and therapeutics. We discuss the promise, practice, challenges, and myths of AI in precision medicine. This show is brought to you by Genialis, and Rafael, our CEO, is your host.
Episodes
Mentioned books

Oct 8, 2024 • 36min
Leave No Patient Behind—R&D Tools and Cutting Edge Diagnostics that Span the Globe | Talking Precision Medicine #39
What a genuine pleasure to sit with Thierry Bernard, CEO of Qiagen. As I told Thierry, Qiagen is a truly iconic brand for anyone who came up through molecular biology laboratories in the past 30 years. Their products were ubiquitous, and crucial, to the success of our research. In this conversation, Thierry talks about his global vision for precision medicine, and his mantra that we leave no patient behind.
Episode 39 links:
TPM E39 for highlights and links from this episode >
Genialis™ krasID Poster at 6th Annual RAS-Targeted Drug Development Summit 2024
Genialis’ Upcoming Events
Genialis on LinkedIn

Aug 29, 2024 • 44min
Zola-007: Giving T-cells the license to kill | Talking Precision Medicine #38
What a pleasure to sit down with my long time colleague and friend, Art Krieg, to discuss his latest venture, Zola Therapeutics, and his adventures in the great outdoors. Art has launched and exited a number of innovative biotechs, each time delving deeper into mechanisms by which we can harness the immune system for therapeutic purposes. Join us as we discuss how — despite a well earned retirement — the siren song that led to Zola was strong enough to get Art back in the game.
Episode 38 links:
TPM E38 for highlights and links from this episode >
Genialis’ Upcoming Events
Genialis™ krasID

Jul 22, 2024 • 39min
Cell therapy for T-cell malignancies—the science and business of developing curative medicines for patients in need | Talking Precision Medicine #37
In this episode I chat with Dr Sarah Hein, co-founder and CEO of March Biosciences, a Houston Based biotech developing cell therapies for T-cell malignancies. Sarah is an old friend and colleague from our days as trainees at Baylor College of Medicine, where we both circulated among those with ambitions of entrepreneurship. Sarah has definitely made good in that regard, as a serial entrepreneur deeply enmeshed in Houston’s growing life sciences and healthtech ecosystem.
Episode 37 links:
TPM E37 for highlights and links from this episode >
Genialis’ Upcoming Events
Genialis™ krasID

May 24, 2024 • 44min
Tackling healthcare disparities and bridging the digital divide: it doesn’t have to be so hard | Talking Precision Medicine #36
This episode features two guests, Jennifer Goldsack and Yashoda Sharma, of the Digital Medicine Society, or DiMe. We’re going to get into the nitty gritty of healthcare disparities in terms of access and outcomes, and how digital solutions are a big part of the overall solution.
Episode 36 links:
TPM E36 for highlights and links from this episode >
Genialis’ Upcoming Events
Genialis™ krasID

Apr 12, 2024 • 31min
The Science and Art of De-risking Cancer Drug Development | Talking Precision Medicine #35
In this episode Genialis CEO Rafael Rosengarten sat down with Dr. Carolina Haefliger, head of translational medicine at Debiopharm, the privately held Swiss biopharma company focused on oncology drug development. They talked about de-risking promising new cancer drugs, and what it takes from the science to the team to the technologies.
Episode 35 links:
Visit TPM E35 for highlights and links from this episode >
Learn more about Genialis™ krasID >
New Genialis RNA Biomarker Accurately Predicts KRAS Outcomes in Lung Cancer Patients >

Dec 14, 2023 • 32min
Professional grade software — a key ingredient in cutting edge biomedical discovery | Talking Precision Medicine #34
Adam Stasio, host of an excellent podcast, discusses the state of scientific software and the importance of agility and communication in biomedical discovery. They also explore building a lasting company culture and the thriving biotech scene in Durham.

Oct 27, 2023 • 43min
New Medicines from Evolutionary Pathways: Using Comparative Genomics to Treat Human Disease | Talking Precision Medicine #33
Our guest today is Dr. Ashley Zehnder, co-founder and CEO of Fauna Bio. Fauna is a revolutionary young biotech company using comparative genomics of an array of non-traditional mammalian models to discover new therapeutic opportunities for people. What do ground squirrels have to do with treating battlefield trauma? Only one way to find out …
Visit TPM E33 for highlights and links from this episode.

7 snips
Aug 2, 2023 • 39min
To achieve personalized medicine, start by getting the dose right | Talking Precision Medicine #32
In this episode, Genialis CEO Rafael Rosengarten sits down with Ajay Gopal, CEO and founder of Rx Studio. Rx Studio is a technology company using data science to tackle a major limitation to personalized medicine: drug dosing.
Visit TPM E32 for highlights and links from this episode.

Jun 29, 2023 • 35min
AI and Ethics in Healthtech: Who is Innovating Most? | Talking Precision Medicine #31
In this episode, Genialis CEO Rafael Rosengarten speaks with BCG management consultant and healthcare innovation expert Amy MacDougall. They discuss emerging trends in healthcare, the role of AI, ethics and more, as well as BCG’s recently released 50 Most Innovative Companies List.
Visit TPM E31 for highlights and links from this episode.

May 31, 2023 • 51min
People first: building a company that inspires impactful work | Talking Precision Medicine #30
This episode, Genialis’ thirtieth, is a bit different from the previous ones. CEO Rafael Rosengarten has not one, not two, but three guests, including the entire leadership team at Genialis. The gang discusses Genialis’ twin quests to build a great place to work and a business that makes a positive impact on the world.
Visit TPM E30 for highlights and links from this episode.