New Books in Neuroscience

This Ideas Roadshow Collection includes five Ideas Roadshow books that have been developed from filmed wide-ranging conversations with the following leading neuroscientists: Lisa Feldman Barrett (Northeastern University), Jennifer Groh (Duke University), Kalanit Grill-Spector (Stanford University), John Duncan (Cambridge University) and Miguel Nicolelis (Duke University). Howard Burton is the founder and host of all Ideas Roadshow Conversations and was the Founding Executive Director of Perimeter Institute for Theoretical Physics. He holds a PhD in theoretical physics and an MA in philosophy.This collection includes a detailed preface highlighting the connections between the different books which offer a uniquely accessible window into frontline research and scholarship while each individual book also includes a detailed introduction plus questions for discussion. These mind-stretching books provide readers through an engaging dialogue format with a wide range of fascinating findings in today's neuroscience research, such as: how the brain combines various streams of sensory input to determine where things are, together with the corresponding implications for a wide range of issues, from neuroplasticity to evolutionary mechanisms; how our brain is anticipating and making sense of sensory inputs from its environment; how functional imaging techniques are used to visualize the brain in action and how it functions to recognize people, objects and places; whether intelligence can be measured and improved; what role our frontal lobe plays in executive control; sophisticated ways of harnessing the thoughts of rats, monkeys and humans to drive mechanical devices in the rapidly emerging field of brain-machine interfaces, and much more.Galina Limorenko is a doctoral candidate in Neuroscience with a focus on biochemistry and molecular biology of neurodegenerative diseases at EPFL in Switzerland. To discuss and propose the book for an interview you can reach her at galina.limorenko@epfl.ch. Learn more about your ad choices. Visit megaphone.fm/adchoicesSupport our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/neuroscience

Why do I feel bad? There is real power in understanding our bad feelings. With his classic Why We Get Sick, Dr. Randolph Nesse helped to establish the field of evolutionary medicine. Now he returns with Good Reasons for Bad Feelings: Insights from the Frontier of Evolutionary Psychiatry (Dutton, 2019), a book that transforms our understanding of mental disorders by exploring a fundamentally new question. Instead of asking why certain people suffer from mental illness, Nesse asks why natural selection has left us all with fragile minds.Drawing on revealing stories from his own clinical practice and insights from evolutionary biology, Nesse shows how negative emotions are useful in certain situations yet can become overwhelming. Anxiety protects us from harm in the face of danger, but false alarms are inevitable. Low moods prevent us from wasting effort in pursuit of unreachable goals, but they often escalate into pathological depression. Other mental disorders, such as addiction and anorexia, result from the mismatch between modern environment and our ancient human past. And there are good evolutionary reasons for sexual disorders and for why genes for schizophrenia persist. Taken together, these and many more insights help to explain the pervasiveness of human suffering and show us new paths for relieving it by understanding individuals as individuals.Renee Garfinkel, Ph.D. is a psychologist, writer, Middle East television commentator and host of The New Books Network’s Van Leer Jerusalem Series on Ideas. Write her at r.garfinkel@yahoo.com. Learn more about your ad choices. Visit megaphone.fm/adchoicesSupport our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/neuroscience

Everyone has heard of the term "pseudoscience", typically used to describe something that looks like science, but is somehow false, misleading, or unproven. Many would be able to agree on a list of things that fall under its umbrella-- astrology, phrenology, UFOlogy, creationism, and eugenics might come to mind. But defining what makes these fields "pseudo" is a far more complex issue. It has proved impossible to come up with a simple criterion that enables us to differentiate pseudoscience from genuine science. Given the virulence of contemporary disputes over the denial of climate change and anti-vaccination movements--both of which display allegations of "pseudoscience" on all sides-- there is a clear need to better understand issues of scientific demarcation.On the Fringe: Where Science Meets Pseudoscience (Oxford UP, 2021) explores the philosophical and historical attempts to address this problem of demarcation. This book argues that by understanding doctrines that are often seen as antithetical to science, we can learn a great deal about how science operated in the past and does today. This exploration raises several questions: How does a doctrine become demonized as pseudoscientific? Who has the authority to make these pronouncements? How is the status of science shaped by political or cultural contexts? How does pseudoscience differ from scientific fraud?Michael D. Gordin both answers these questions and guides readers along a bewildering array of marginalized doctrines, looking at parapsychology (ESP), Lysenkoism, scientific racism, and alchemy, among others, to better understand the struggle to define what science is and is not, and how the controversies have shifted over the centuries. On the Fringe provides a historical tour through many of these fringe fields in order to provide tools to think deeply about scientific controversies both in the past and in our present.Marshall Poe is the founder and editor of the New Books Network. He can be reached at marshallpoe@newbooksnetwork.com. Learn more about your ad choices. Visit megaphone.fm/adchoicesSupport our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/neuroscience

In 2020, an estimated 5.8 million Americans had Alzheimer’s, and more than half a million died because of the disease and its devastating complications. 16 million caregivers are responsible for paying as much as half of the $226 billion annual costs of their care. As more people live beyond their seventies and eighties, the number of patients will rise to an estimated 13.8 million by 2025.Part case studies, part meditation on the past, present and future of the disease, The Problem of Alzheimer's: How Science, Culture, and Politics Turned a Rare Disease into a Crisis and What We Can Do About It (St. Martin's Press, 2021) traces Alzheimer’s from its beginnings to its recognition as a crisis. While it is an unambiguous account of decades of missed opportunities and our health care systems’ failures to take action, it tells the story of the biomedical breakthroughs that may allow Alzheimer’s to finally be prevented and treated by medicine and also presents an argument for how we can live with dementia: the ways patients can reclaim their autonomy and redefine their sense of self, how families can support their loved ones, and the innovative reforms we can make as a society that would give caregivers and patients better quality of life.Rich in science, history, and characters, The Problem of Alzheimer's takes us inside laboratories, patients' homes, caregivers’ support groups, progressive care communities, and Jason Karlawish's own practice at the Penn Memory Center.Galina Limorenko is a doctoral candidate in Neuroscience with a focus on biochemistry and molecular biology of neurodegenerative diseases at EPFL in Switzerland. To discuss and propose the book for an interview you can reach her at galina.limorenko@epfl.ch. Learn more about your ad choices. Visit megaphone.fm/adchoicesSupport our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/neuroscience

Dip below the ocean’s surface and you are soon confronted by forms of life that could not seem more foreign to our own: sea sponges, soft corals, and serpulid worms, whose rooted bodies, intricate geometry, and flower-like appendages are more reminiscent of plant life or even architecture than anything recognizably animal. Yet these creatures are our cousins. As fellow members of the animal kingdom—the Metazoa—they can teach us much about the evolutionary origins of not only our bodies, but also our minds.In his acclaimed 2016 book, Other Minds, the philosopher and scuba diver Peter Godfrey-Smith explored the mind of the octopus—the closest thing to an intelligent alien on Earth. In Metazoa: Animal Life and the Birth of the Mind (FSG, 2020), Godfrey-Smith expands his inquiry to animals at large, investigating the evolution of subjective experience with the assistance of far-flung species. As he delves into what it feels like to perceive and interact with the world as other life-forms do, Godfrey-Smith shows that the appearance of the animal body well over half a billion years ago was a profound innovation that set life upon a new path. In accessible, riveting prose, he charts the ways that subsequent evolutionary developments—eyes that track, for example, and bodies that move through and manipulate the environment—shaped the subjective lives of animals. Following the evolutionary paths of a glass sponge, soft coral, banded shrimp, octopus, and fish, then moving onto land and the world of insects, birds, and primates like ourselves, Metazoa gathers their stories together in a way that bridges the gap between mind and matter, addressing one of the most vexing philosophical problems: that of consciousness.Combining vivid animal encounters with philosophical reflections and the latest news from biology, Metazoa reveals that even in our high-tech, AI-driven times, there is no understanding our minds without understanding nerves, muscles, and active bodies. The story that results is as rich and vibrant as life itself.Peter Godfrey-Smith is a professor in the School of History and Philosophy of Science at the University of Sydney. He is the author of the bestselling Other Minds: The Octopus, the Sea, and the Deep Origins of Consciousness, which has been published in more than twenty languages. His other books include Theory and Reality: An Introduction to the Philosophy of Science and Darwinian Populations and Natural Selection, which won the 2010 Lakatos Award.Mark Molloy is the reviews editor at MAKE: A Literary Magazine. Learn more about your ad choices. Visit megaphone.fm/adchoicesSupport our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/neuroscience

Through discussion of his famous 1970s experiment alongside new research, in Why Chimpanzees Can’t Learn Language and Only Humans Can (Columbia University Press, 2019), Herbert Terrace argues that, despite the failure of famous attempts to teach primates to speak, from these efforts we can learn something important: the missing link between non-linguistic and linguistic creatures is the ability to use words, not to form sentences. Situating language-learning as a capacity gained through conversation, not primarily representing internal thought, Terrace takes naming as the first step towards language. By drawing on research in developmental psychology, paleoanthropology, and linguistics, Terrace builds a case for understanding human language as grounded in social interaction between mother and child, rather than an inevitable, asocial result of a person’s development.Malcolm Keating is Assistant Professor of Philosophy at Yale-NUS College. His research focuses on Sanskrit philosophy of language and epistemology. He is the author of Language, Meaning, and Use in Indian Philosophy (Bloomsbury Press, 2019) and host of the podcast Sutras (and stuff). Learn more about your ad choices. Visit megaphone.fm/adchoicesSupport our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/neuroscience

A compassionate and captivating examination of evolving attitudes toward mental illness throughout history and the fight to end the stigma.For centuries, scientists and society cast moral judgments on anyone deemed mentally ill, confining many to asylums. In Nobody's Normal: How Culture Created the Stigma of Mental Illness (W. W. Norton & Company, 2021), anthropologist Roy Richard Grinker chronicles the progress and setbacks in the struggle against mental-illness stigma—from the eighteenth century, through America’s major wars, and into today’s high-tech economy.Nobody’s Normal argues that stigma is a social process that can be explained through cultural history, a process that began the moment we defined mental illness, that we learn from within our communities, and that we ultimately have the power to change. Though the legacies of shame and secrecy are still with us today, Grinker writes that we are at the cusp of ending the marginalization of the mentally ill. In the twenty-first century, mental illnesses are fast becoming a more accepted and visible part of human diversity.Grinker infuses the book with the personal history of his family’s four generations of involvement in psychiatry, including his grandfather’s analysis with Sigmund Freud, his own daughter’s experience with autism, and culminating in his research on neurodiversity. Drawing on cutting-edge science, historical archives, and cross-cultural research in Africa and Asia, Grinker takes readers on an international journey to discover the origins of, and variances in, our cultural response to neurodiversity.Urgent, eye-opening, and ultimately hopeful, Nobody’s Normal explains how we are transforming mental illness and offers a path to end the shadow of stigma.Galina Limorenko is a doctoral candidate in Neuroscience with a focus on biochemistry and molecular biology of neurodegenerative diseases at EPFL in Switzerland. To discuss and propose the book for an interview you can reach her at galina.limorenko@epfl.ch. Learn more about your ad choices. Visit megaphone.fm/adchoicesSupport our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/neuroscience

Alzheimer’s disease, a haunting and harrowing ailment, is one of the world’s most common causes of death. Alzheimer’s lingers for years, with patients’ outward appearance unaffected while their cognitive functions fade away. Patients lose the ability to work and live independently, to remember and recognize. There is still no proven way to treat Alzheimer’s because its causes remain unknown.Mind Thief: The Story of Alzheimer's (Columbia UP, 2021) is a comprehensive and engaging history of Alzheimer’s that demystifies efforts to understand the disease. Beginning with the discovery of “presenile dementia” in the early twentieth century, Han Yu examines over a century of research and controversy. She presents the leading hypotheses for what causes Alzheimer’s; discusses each hypothesis’s tangled origins, merits, and gaps; and details their successes and failures. Yu synthesizes a vast amount of medical literature, historical studies, and media interviews, telling the gripping stories of researchers’ struggles while situating science in its historical, social, and cultural contexts. Her chronicling of the trajectory of Alzheimer’s research deftly balances rich scientific detail with attention to the wider implications. In narrating the attempts to find a treatment, Yu also offers a critical account of research and drug development and a consideration of the philosophy of aging. Wide-ranging and accessible, Mind Thief is an important book for all readers interested in the challenge of Alzheimer’s. Learn more about your ad choices. Visit megaphone.fm/adchoicesSupport our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/neuroscience

An exposé of the corruption of medicine by the pharmaceutical industry at every level, from exploiting the vulnerable destitute for drug testing, through manipulation of research data, to disease mongering and promoting drugs that do more harm than good.Authors, Professor Jon Jureidini and Dr Leemon McHenry, made critical contributions to exposing the scientific misconduct in two infamous trials of antidepressants. Ghostwritten publications of these trials were highly influential in prescriptions of paroxetine (Paxil) and citalopram (Celexa) in paediatric and adolescent depression, yet both trials (Glaxo Smith Kline's paroxetine study 329 and Forest Laboratories' citalopram study CIT-MD-18) seriously misrepresented the efficacy and safety data.The Illusion of Evidence-Based Medicine: Exposing the Crisis of Credibility in Clinical Research (Wakefield Press, 2020) provides a detailed account of these studies and argues that medicine desperately needs to re-evaluate its relationship with the pharmaceutical industry. Without a basis for independent evaluation of the results of randomised, placebo-controlled clinical trials, there can be no confidence in evidence-based medicine.Science demands rigorous, critical examination and especially severe testing of hypotheses to function properly, but this is exactly what is lacking in academic medicine. Learn more about your ad choices. Visit megaphone.fm/adchoicesSupport our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/neuroscience

Would your dog eat you if you died? What are face mites? Why do clowns creep us out? In this illuminating collection of grisly true science stories, journalist Erika Engelhaupt, the writer of National Geographic’s highly acclaimed Gory Details blog, shares the answers to these questions and many more. Gory Details: Adventures from the Dark Side of Science (National Geographic, 2020) explores the strange and shocking realities of our minds, our bodies and our universe, taking readers on a fascinating tour through overlooked but astonishing aspects of biology, anatomy, nature and more, as well as the ways that science helps to break down taboos surrounding such conversation topics as women’s bodies.Blending humor and real science, Engelhaupt shares captivating stories and intriguing research that will alter the way readers view the world. From a peek inside the world's smallest crime scenes to a hands-on look at maggot farming, Gory Details features top-notch reporting, interviews with leading scientists and a healthy dose of wit. Galina Limorenko is a doctoral candidate in Neuroscience with a focus on biochemistry and molecular biology of neurodegenerative diseases at EPFL in Switzerland. To discuss and propose the book for an interview you can reach her at galina.limorenko@epfl.ch. Learn more about your ad choices. Visit megaphone.fm/adchoicesSupport our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/neuroscience