Mayo Clinic Talks

To claim credit for this episode, visit: Mayo Clinic Talks Podcast: Genes & Your Health Guests: Megan A. Allyse, Ph.D. (@MAllyse); Jennifer (Jenny) L. Anderson, M.S., CGC; Radhika Dhamija, M.B.B.S. (@NeurogenesDr) Host: Denise M. Dupras, M.D., Ph.D. Genetic testing is increasingly becoming mainstream. Not only is it first-line testing for many different indications, but we have begun seeing an increase in predictive genomics for healthy patients as well. How can your practice prepare for what is here and what is to come? Tune in to this episode of the Genes & Your Health miniseries from the Center for Individualized Medicine to find out. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

Guest: Rozalina G. McCoy, M.D., M.S. (@RozalinaMD) Host: Amit K. Ghosh, M.D. (@AmitGhosh006) Diabetic research starts with understanding contemporary treatment practices (overtreatment and undertreatment, misuse or underuse of glucose-lowering medications, comparative effectiveness of different diabetes medications), the resulting impact on patient health and the disparities in both treatment practices and outcomes. In this episode Rozalina McCoy, M.D., M.S., associate professor of medicine and consultant in the Division of Community Internal Medicine at Mayo Clinic’s Rochester campus, joins us to discuss developing care delivery models that support high-quality, evidence-based, patient-centered, and equitable diabetes care. Additional resources: McCoy RG, Galindo RJ, Swarna KS, et al. Sociodemographic, clinical, and treatment-related factors associated with hyperglycemic crises among adults with type 1 or type 2 diabetes in the US from 2014 to 2020. JAMA Netw Open. 2021;4(9):e2123471. doi:1001/jamanetworkopen.2021.23471 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

To claim credit for this episode, visit: Mayo Clinic Talks Podcast: Genes & Your Health Guest: Iftikhar J. Kullo, M.D. (@iftikhar_kullo) Host: Denise M. Dupras, M.D., Ph.D. What is familial hypercholesterolemia? Who should be tested for it? Are there genetic variants that are associated with cardiovascular diseases? How young do we start screening? This installment of the Genes & Your Health miniseries from the Center for Individualized Medicine is here to help answer these questions and more! Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

Guest: Sophie J. Bakri, M.D. Host: Darryl S. Chutka, M.D. (@ChutkaMD) Macular degeneration is the most common cause of vision loss in individuals over the age of 50. The loss of central vision from macular degeneration can result in significant lifestyle changes in patients. They may no longer be able to read, write or drive. In this podcast, we’ll discuss macular degeneration with Sophie Bakri, M.D., an ophthalmologist at Mayo Clinic. She’ll review the two types and pathology of macular degeneration, its presentation, risk factors and preventive strategies, and new treatments on the horizon. Specific topics: Pathologic changes in macular degeneration Vision loss associated with macular degeneration Possible causes of macular degeneration Risk factors Typical course of macular degeneration The difference between wet and dry macular degeneration Treatment strategies Preventive strategies Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

This episode is shared from Mayo Clinic Q&A and was recorded in October, 2021 Guest:  Gregory A. Poland, M.D. (@drgregpoland) Host: Halena M. Gazelka, M.D. (@hmgazelkamd) As continuing research guides medical recommendations, it seems that there are COVID-19 updates released daily. These recommendations cover a range of topics, including whether COVID-19 booster vaccinations are necessary to whether COVID-19 vaccines can be mixed and matched. "The fact that recommendations are changing is not evidence people don't know what they're doing," says Dr. Gregory Poland, head of Mayo Clinic's Vaccine Research Group. "It's evidence that they do know what they're doing and are paying close attention to new data that's coming along. Then they're adjusting recommendations based on the latest data." Dr. Poland continues to urge people to get the latest COVID-19 news from credible sources.  In this Mayo Clinic Q&A podcast, Dr. Poland walks through the recent recommendations, corrects misperceptions and answers a number of listener questions. AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

To claim credit for this episode, visit: Mayo Clinic Talks Podcast: Genes & Your Health Guests: Minetta C. Liu, M.D.; Myra J. Wick, M.D., Ph.D. (@MyraWickMD) Host: Denise M. Dupras, M.D., Ph.D. What is cell-free DNA? How does this type of DNA interact with our body? How is it useful in the clinical setting? Advances in technologies has expanded our understanding of cell-free DNA and its implications. Where are we now and what can we look for in the future? Find out these answers and more in the seventh episode of the Genes & Your Health miniseries from the Center for Individualized Medicine. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

Guest: Paola Sandroni, M.D., Ph.D. Host: Amit K. Ghosh, M.D. (@AmitGhosh006) Syncope is defined as the sudden and transient loss of consciousness and postural tone due to global reduction of blood flow to the reticular activating system. Syncopal episodes are followed by a rapid and spontaneous recovery.  Joining us today is Paola Sandroni, M.D., Ph.D., a neurologist at Mayo Clinic’s Rochester Campus. She will help us sort through the complicated subject of syncope, including its main etiologies and how to distinguish which is affecting your patient. She also outlines the nuances of evidence-based evaluation of syncope, which is largely guided by the patient’s presentation. Additional resources: Thiruganasambandamoorthy V, Kwong K, Wells GA, Sivilotti MLA, Mukarram M, Rowe BH, Lang E, Perry JJ, Sheldon R, Stiell IG, Taljaard M. Development of the Canadian Syncope Risk Score to predict serious adverse events after emergency department assessment of syncope. CMAJ. 2016 Sep 6;188(12):E289-E298. doi: 1503/cmaj.151469. Epub 2016 Jul 4. PMID: 27378464; PMCID: PMC5008955 Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

To claim credit for this episode, visit: Mayo Clinic Talks Podcast: Genes & Your Health Guests: Stephanie S. Faubion, M.D., M.B.A. (@StephFaubionMD); Kejal Kantarci, M.D. (@KejalKantarciMD); Juliana (Jewel) M. Kling, M.D., M.P.H. (@DrJewelKling) Host: Denise M. Dupras, M.D., Ph.D. Is hormone therapy good or bad for women? What are the myths surrounding it? Is the varying experience of menopause genetic? Join the sixth episode of Mayo Clinic Center for Individualized Medicine’s Genes & Your Health Edition to dive into women’s health and hormones and what you need to know for your practice.   Additional resources: • USPSTF Recommendations Statement for Breast Cancer: Medication Use to Reduce Risk https://www.uspreventiveservicestaskforce.org/uspstf/recommendation/breast-cancer-medications-for-risk-reduction  • Mayo Clinic Center for Individualized Medicine: https://www.mayo.edu/research/centers-programs/center-individualized-medicine  Connect with the Mayo Clinic School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

Guest: Thomas Caulfield, Ph.D. Host: Amit K Ghosh, M.D., MBA (@AmitGhosh006) In this podcast, Dr. Thomas Caulfield from Mayo Clinic Florida describes a novel approach for SARS-CoV2 multi-drug targeting using artificial intelligence. Dr. Caulfield is leading a national team of investigators from Harvard, University of California, In Vivo Biosystems and Mayo Clinic to perform large-scale in silico and in vivo experiments on de novo drugs to better understand COVID-19 and halt its progression.  University of California hosts a live virus BSL3 facility for rapidly screening novel compounds that Dr. Caulfield's lab designs in silico and refines with feedback using machine learning techniques and data layering. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

To claim credit for this series, visit: Mayo Clinic Talks Podcast: Genes & Your Health Guest: Purna C. Kashyap, M.B.B.S. (@KashyapPurna); Marina R. Walther-Antonio, Ph.D. Host: Denise M. Dupras, M.D., Ph.D. What is the microbiome? How does the microbiome interact with our body? How much of us is nurture, how much is nature? The whole concept of microbiome may be a new idea but have no fear this fifth episode of the Genes & Your Health Edition from the Mayo Clinic Center for Individualized Medicine is here to help answer those questions and more! Additional resources: Mayo Clinic Center for Individualized Medicine: https://www.mayo.edu/research/centers-programs/center-individualized-medicine  Connect with the Mayo Clinic School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.