Mayo Clinic Talks

Renowned headache specialist, Jerry W. Swanson, discusses the underappreciation of headaches in the medical field and advancements in migraine treatments. The podcast explores the significant impact of migraines on patients' lives and the need for accurate diagnosis and effective management. It concludes with a message of gratitude and promotion of other medical topics available on Mayo Clinic Talks podcasts.

Guest: Brendan C. Lanpher, M.D. Host: David J. Sas, D.O. (@davidsas1) Inborn errors of metabolism can present in a variety of ways depending on the specific type of disease.  The most critical presentation to identify occurs in the neonatal period when more severe diseases can cause acute decompensation.  These patients require appropriate evaluation and timely, expert management for good outcomes.  Diagnostic testing, including newborn screening, is advancing rapidly as are innovative treatment methods, making this an exciting field for clinicians. The guest for this episode is Brendan C. Lanpher, M.D., a board-certified geneticist at the Mayo Clinic Children’s Center in Rochester, Minnesota. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

Host: Joshua D. Luciew, MPAS, P.A.-C.    Guest: Neeta Jain, M.D. Depression is a common condition that we see in our practices. It is a multifactorial disease that can affect patients of all ages. In this episode, we discuss women and depression, as women are twice as likely as men to receive this diagnosis. We will explore how this condition is diagnosed, depression subtypes, what effect hormones have on a woman’s mental health, and how we can help treat this condition for our patients through various parts of their life. The guest for today’s episode is Neeta Jain, M.D., Mayo Clinic Board Certified Psychiatrist at Mayo Clinic in Arizona. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

Guest: Candace F. Granberg, M.D. (@candacegranberg) Host: David J. Sas, D.O. (@davidsas1) Detection and management of undescended testicles (cryptorchidism) is a common issue for newborn and infant boys.  This episode discusses proper diagnostic techniques for cryptorchidism, including how to distinguish between a retractile testicle and a truly undescended testicle, as well as when to refer infants to a pediatric urologist for further evaluation and management.  Further, we identify the indications for surgical correction and what parents and pediatricians should expect from this surgery. The guest for this episode is Candace F. Granberg, M.D., a board-certified pediatric urologist at the Mayo Clinic Children’s Center in Rochester, Minnesota. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

Irina Bancos, an endocrinologist at the Mayo Clinic, discusses the symptoms, diagnosis, and management of adrenal insufficiency. Topics covered include different types of adrenal insufficiency, necessary investigations for diagnosis, replacement of hormones, tapering glucocorticoid use, and the importance of considering adrenal insufficiency in patients with nonspecific symptoms.

This episode is shared from Mayo Clinic Q&A and was recorded in May 2022 Guest: Gregory A. Poland, M.D. (@drgregpoland) Host: Halena M. Gazelka, M.D. (@hmgazelkamd) The widespread availability of at-home COVID-19 tests have made it easier for people to know if they have the virus, and to take measures to protect themselves and others. But there is a downside. Because the majority of tests are now done at home and often not reported, the official counts on COVID-19 infection rates are not as accurate as they have been in past waves of the virus.  "Because the majority of testing is being done at home, we can no longer tell you accurately about the positivity rate for a given community for a given state like we used to be able to," explains Dr. Gregory Poland, head of Mayo Clinic's Vaccine Research Group. "And this is problematic. It means that we lose our ability to understand what's called genetic epidemiology — the ability to trace how these variants are moving, how fast they're moving, and whether they're changing and evolving into yet different subvariants or new variants. We've lost that ability now." The most recent omicron subvariant, BA 2.12.1, has cases on the rise again and the U.S. passed a tragic milestone last week, reaching 1 million COVID-19 deaths in the country. In an effort to capture a more accurate picture, the latest tool being used by public health officials to track COVID-19 infection rates is wastewater surveillance. By looking for the presence of the COVID-19 virus shed by people, wastewater surveillance can give a more accurate picture of how much virus is in the community. This detects virus not only from those who test at home, but also from people who are asymptomatic and, therefore, didn't get tested. On the Mayo Clinic Q&A podcast, Dr. Poland discusses the current state of COVID-19 in the U.S., including what we know about the latest subvariants.

Guest: Irina Bancos, M.D. (@IrinaBancos) Host: Darryl S. Chutka, M.D. (@ChutkaMD) The widespread use of CT and MRI scans has resulted in frequent serendipitous findings, including adrenal nodules. When these nodules are found, two questions need to be answered. Is the nodule malignant and is this nodule metabolically active? This podcast will address these incidentally found adrenal nodules, also known as adrenal incidentalomas. We’ll review when these nodules should be investigated, the likelihood they represent a malignancy and how to assess if they’re metabolically active. Our guest for this podcast is Irina Bancos, M.D., an endocrinologist at the Mayo Clinic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

To claim credit for this episode, visit: Mayo Clinic Talks Podcast: Eating Disorders Edition Guest(s):   Scott Crow, M.D.; Carol B. Peterson, Ph.D., L.P. Host:  Jocelyn R. Lebow, Ph.D., L.P. While eating disorders are often thought of as disorders of adolescence, they impact adult patients across their lifespan. While many of the characteristics of these disorders are similar for pediatric vs. adult patients, there are important differences in how a primary care provider should assess and treat these illnesses in adults. As with younger patients, most adults report presenting initially to their primary care provider with their eating concerns, and many never seek additional care. This episode focuses on best practices for primary care providers in assessing and treating adult patients with eating disorders. Our guests are Scott Crow, M.D., Adjunct Professor of Psychiatry at the University of Minnesota and Vice President of Psychiatry at Accanto Health, and Carol B. Peterson, Ph.D., L.P., Clinical Psychologist and Professor in the Department of Psychiatry and Behavioral Sciences at the University of Minnesota. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

Guest: Raymund R. Razonable, M.D. Host: Darryl S. Chutka, M.D. (@ChutkaMD) Monoclonal antibodies are laboratory-synthesized and mimic our immune system in fighting harmful pathogens. In addition to convalescent plasma and anti-viral medication, monoclonal antibodies have played an important role in the treatment of infections due to COVID-19. The use of monoclonal antibodies has been shown to shorten the duration of symptoms as well as reduce the risk of hospitalization and mortality due to COVID-19. This podcast will focus on monoclonal antibodies and our guest is Raymund R. Razonable, M.D., from the Division of Infectious Disease at the Mayo Clinic. Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. Resource: O’Horo J, Challener DW, Anderson RJ, Arndt RF, Ausman SE, Hall ST, Heyliger A, Kennedy BD, Sweeten PW, Ganesh R, Razonable RR, Rates of Severe Outcomes After Bamlanivimab-Etesevimab and Casirivimab-Imdevimab Treatment of High-Risk Patients With Mild to Moderate Coronavirus Disease-2019, Mayo Clinic Proceedings (2022), doi: https://doi.org/10.1016/j.mayocp.2022.02.009.

This episode is shared from Mayo Clinic Q&A and was recorded in April 2022 Guest: Gregory A. Poland, M.D. (@drgregpoland) Host: Halena M. Gazelka, M.D. (@hmgazelkamd) An estimated 3 out of 4 U.S. children and more than half of all adults have been infected with COVID-19, according to a report released on Tuesday, April 26 by the Centers for Disease Control and Prevention. But a Mayo Clinic expert says more information is needed to get the complete picture. "This was a convenient sample. In other words, people who were having blood drawn for other reasons were tested,"explains Dr. Gregory Poland, head of Mayo Clinic's Vaccine Research Group. "That does not reflect the full population or differences by race or geographic location. And the detection of antibodies does not necessarily mean that you are protected from infection. So, there's a lot of nuance around understanding that headline." The research study looked at more than 200,000 blood samples and found that signs of past infection rose dramatically during the omicron surge between December 2021 and February. Other COVID-19 news this week includes a push to make treatments more available, the rising incidence of new omicron subvariants, and changes in mask recommendations. Dr. Poland cautions that COVID-19 is still present and encourages wearing a mask in crowded spaces, even when there isn't a requirement to do so. "If only one of us is wearing a mask and the other one isn't and is infected, you still have pretty high protection — but not the same level of protection as if both of us wearing one," says Dr. Poland. "So, it's it is not futile to be the only one wearing a mask. In fact, I think it sends a message." On the Mayo Clinic Q&A podcast, Dr. Poland discusses the latest COVID-19 news and answers listener questions.