The Proof with Simon Hill

In this solo episode of The Proof, I explore how to turn your gut into a thriving ecosystem and what might be silently harming it. You’ll learn the top 3 things to do for your microbiome, the 3 biggest mistakes to avoid, and how to support gut recovery after antibiotics. Specifically, I cover: How your microbiome affects immunity, mood, metabolism, and more The best foods and habits to feed your gut My antibiotic recovery protocol Why plant diversity matters more than your diet label Gut health myths (like probiotic hype and “7-day resets”) Signs your gut health is improving without testing Science-backed and practical. No fads, just evidence. How to Transform Your Gut Health Naturally (00:00) What Is the Gut Microbiome? (01:27) How Your Microbiome Supports the Immune System (02:08) The Gut-Brain Connection: How Microbes Influence Mood (03:17) Why the Gut Microbiome Changes Daily — And What It Means for Your Health (04:18) Top Expert-Backed Tips for a Healthy Gut Microbiome (04:43) Why Plant Diversity Is Crucial for Gut Health (05:15) Best Fermented Foods to Improve Gut Health (11:42) How Lifestyle Affects Your Gut Microbiome (15:35) Busting the Biggest Gut Health Myths (18:00) What’s Harming Your Gut? 3 Practices to Avoid (18:54) How to Heal Your Gut After Taking Antibiotics (20:47) Key Takeaways for Long-Term Gut Health Success (28:43) Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family. This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Pique Tea Pique's Nandaka provides sustainable, all-day energy and makes you feel like you’re doing something good for your body! Try Pique and get 20% off plus a FREE starter kit when you shop exclusively at Piquelife.com/simon. Function Health Track, optimise, and thrive with Function Health. Access 100+ lab tests – five times more than a typical physical – including ApoB and LP(a), no doctor approval needed. Get science-backed insights and track your results over time. Skip the 400,000-person waitlist at functionhealth.com/simonhill. Only available to those living in the United States. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Follow [this link](https://eimele.com/essential-8/15660280.html.) for 20% off one-time purchases and subscriptions. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Simon Hill, MSc, BSc (Hons) • Creator of theproof.com • Host of The Proof with Simon Hill • Author of The Proof is in the Plants Subscribe & Connect: • YouTube • Apple Podcasts • Spotify • Instagram: @simonhill • Twitter: @theproof • Facebook: The Proof with Simon Hill Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.

How can we protect our brain as we age and what can we do today to boost memory, focus, and resilience?In this episode of The Proof, I’ve compiled some of the most impactful conversations I’ve had with leading neuroscientists, neurologists, and brain health researchers to explore exactly that.From building better habits to slowing age-related decline, this masterclass brings you practical, science-backed strategies for optimising brain function, now and in the future.Whether your goal is sharper mental clarity, prevention of neurodegenerative disease, or simply staying sharp for the long haul, this episode is packed with insights you can use right away.You’ll learn:• How neuroplasticity allows your brain to adapt and change at any age• The role of movement and VO₂ max in protecting cognitive performance• How omega-3s and dietary fats impact brain structure and function• What APOE4 means for your risk of Alzheimer’s and why genetics aren’t destiny• The link between cardiovascular health, lipoproteins, and dementia• How the microbiome and inflammation influence brain aging• The surprising ways exercise improves brain volume and connectivity• Why creatine isn’t just for muscles and how it may enhance mental energy and mood• Actionable daily habits to reduce your risk of cognitive decline• The truth about lifestyle vs genetics when it comes to Alzheimer’s diseaseFeaturing insights from Dr Andrew Huberman, Dr Ayesha Sherzai, Dr Dean Sherzai, Dr Thomas Dayspring, and Dr Kellyann Niotis, this episode distills cutting-edge neuroscience into clear, practical guidance for long-term cognitive health.Thank you for tuning in to today’s episode, and special thanks to the experts featured for their invaluable insights. If you found this episode helpful, please share it with someone who you think might benefit from it.Want to support the show?The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family.This episode is brought to you by:38TERAConsider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout.Function HealthTrack, optimise, and thrive with Function Health. Access 100+ lab tests – five times more than a typical physical – including ApoB and LP(a), no doctor approval needed. Get science-backed insights and track your results over time. Skip the 400,000-person waitlist at functionhealth.com/simonhill. Only available to those living in the United States.Eight SleepUpgrade your sleep with the Pod 4 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF for $350 off at eightsleep.com/theproof. Try it risk-free for 30 days, with worldwide shipping.MomentousMy go-to supplement brand for protein and creatine is Momentous. Get 20% off your first purchase by using the code LIVINGPROOF at checkout at livemomentous.comEimeleEimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Follow [this link](https://eimele.com/essential-8/15660280.html.) for 20% off one-time purchases and subscriptions.Simon Hill, MSc, BSc (Hons)• Creator of theproof.com• Host of The Proof with Simon Hill• Author of The Proof is in the PlantsSubscribe & Connect:• YouTube• Apple Podcasts• Spotify• Instagram: @simonhill• Twitter: @theproof• Facebook: The Proof with Simon HillNourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.

In today’s episode Dr Matthew Nagra returns to The Proof to break down a new JAMA Internal Medicine study on butter, plant-based oils, and mortality. Over 200,000 Americans were followed for 33 years — so what did the research really find?We unpack the study’s most talked-about claims, including whether swapping just 10g of butter for plant-based oil could lower your risk of early death. Plus, we dive into the bigger picture: Why fats are so polarising, the debate around seed oils, and how to navigate nutrition science in an era of misinformation.Specifically, we cover: Inside a Controversial New Study on Butter and Plant Oils (00:00) How the 33-Year Nutrition Study Was Conducted (00:47) What Observational Studies Can (and Can’t) Tell Us (03:01) The Truth About Food Frequency Questionnaires (08:03) Surprising Patterns in Butter and Oil Consumption (17:52) Why One Common Oil Performed Better Than Expected (22:50) Are We Misunderstanding Nutrition Guidelines? (26:13) What Happens When Oils Are Heated Over and Over (28:28) Do Oils Measure Up to Whole Food Fat Sources? (31:04) The Great Oil Debate: A Preview and Reflection (34:07) A Smarter Way to Navigate Conflicting Health Advice (43:40) Want to support the show?The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family.This episode is brought to you by:38TERAConsider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout.MomentousMy go-to supplement brand for protein and creatine is Momentous. Get 20% off your first purchase by using the code LIVINGPROOF at checkout at livemomentous.comShopifyShopify, the world's leading e-commerce platform, helps you turn browsers into buyers with the internet’s best-converting check out–up to 36% better compared to other leading e-commerce platforms. To boost your conversion rate, and grow your business, sign up for a one-dollar-per-month trial period at shopify.com/proof.BirchSleep deeply and wake up refreshed with a Birch Natural Mattress, combining premium natural materials with unbeatable comfort. Rest easy with a 100-night trial and 25-year warranty. Get 20% off sitewide and 2 free Eco-Rest Pillows at birchliving.com/simonhill.EimeleEimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Follow [this link](https://eimele.com/essential-8/15660280.html.) for 20% off one-time purchases and subscriptions.WHOOPWhoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon.Simon Hill, MSc, BSc (Hons)• Creator of theproof.com• Host of The Proof with Simon Hill• Author of The Proof is in the PlantsSubscribe & Connect:• YouTube• Apple Podcasts• Spotify• Instagram: @simonhill• Twitter: @theproof• Facebook: The Proof with Simon HillNourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.

What if losing body fat didn’t have to be so difficult?In this episode, I share five practical, science-backed strategies to support fat loss in a sustainable way. No gimmicks. No pseudo-science. Just real tools to help you feel fuller, fuel your body better, and improve metabolic health.Whether your goal is to reduce visceral fat or feel more confident in your body, these strategies can help — and you don’t need to do them all at once to see results.In this episode, I cover: Why energy density matters The “preload” trick that helps regulate intake How eating slower naturally reduces appetite The surprising role of gut microbes in hunger Why protein + fibre is the ultimate combo A flexible approach to time-restricted eating Plus, I bust common weight loss myths and share why improving body composition is about more than aesthetics.If you’re ready for a science-based, sustainable approach to fat loss — without restriction — this episode is for you. Introduction (00:00) Should You Choose Low Energy Dense Foods? (01:39) Could Slowing Down Your Eating Help? (07:51) How Can You Feed Your Gut Microbes? (12:29) Why Increase Your Protein Intake? (15:41) Does Reducing Your Eating Window Work? (19:27) Recap and Final Thoughts (21:03) Conclusions (22:16) Want to support the show?The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family.This episode is brought to you by:38TERAConsider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for 25% at checkout.Eight SleepUpgrade your sleep with the Pod 4 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF for $350 off at eightsleep.com/theproof. Try it risk-free for 30 days, with worldwide shipping.Function HealthTrack, optimise, and thrive with Function Health. Access 100+ lab tests – five times more than a typical physical – including ApoB and LP(a), no doctor approval needed. Get science-backed insights and track your results over time. Skip the 400,000-person waitlist at functionhealth.com/simonhill. Only available to those living in the United States.EimeleEimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Follow [this link](https://eimele.com/essential-8/15660280.html.) for 20% off one-time purchases and subscriptions.WHOOPWhoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon.Simon Hill, MSc, BSc (Hons)• Creator of theproof.com• Host of The Proof with Simon Hill• Author of The Proof is in the PlantsSubscribe & Connect:• YouTube• Apple Podcasts• Spotify• Instagram: @simonhill• Twitter: @theproof• Facebook: The Proof with Simon HillNourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.

Welcome to the very first episode of a brand new format - something a little more relaxed, more personal, and more conversational.Think of this as us sitting on the couch or going for a long walk together. No script. No structure. Just your questions, and my honest thoughts.In this episode, I answer your voice notes and DMs - covering: Intro (00:00) How Can New Fathers Balance Fitness and Diet with a Busy Life? (02:20) What Are the Risks and Benefits of Methylene Blue? (12:20) What Are the Biggest Nutrition Myths Still Believed in 2025? (16:59) Why Do Some Plant-Based Eaters Still Have High Cholesterol? (19:52) What Are the Best Alternatives to Statins for Lowering APOB? (23:32) What Health Habits Does Simon Hill Personally Struggle With? (32:41) Are Refined Carbohydrates Like Pasta and White Rice Actually Bad for You? (34:09) What’s the Future of Personalised Nutrition? (40:16) What’s the Most Embarrassing Travel Story Simon Has Shared? (44:33) What Does “Bogan” Mean in Australian Slang? (47:49) How Much Omega-3 Do You Really Need Daily? (50:06) Does Creatine Supplementation Harm Your Kidneys? (56:10) What’s the Perfect Meal for Human and Planetary Health? (01:00:31) Can the Power of Belief Affect Your Health Outcomes? (01:03:05) What’s the Funniest Listener Question and Final Thoughts? (01:04:11) Some serious, some silly - but all of it real. I hope you enjoy this new format, and as always, I’d love your feedback. Let me know what you liked, didn’t like, and what you’d love to see more of in future episodes.If you’d like to leave a question for a future Q&A episode, you can do that in the YT comments or send a message on IG instagram.com/simonhill.Want to support the show?The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family.This episode is brought to you by:38TERAConsider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout.BirchSleep deeply and wake up refreshed with a Birch Natural Mattress, combining premium natural materials with unbeatable comfort. Rest easy with a 100-night trial and 25-year warranty. Get 20% off sitewide and 2 free Eco-Rest Pillows at birchliving.com/simonhill.Pique TeaPique's Nandaka provides sustainable, all-day energy and makes you feel like you’re doing something good for your body! Try Pique and get 20% off plus a FREE starter kit when you shop exclusively at Piquelife.com/simon.Eight SleepUpgrade your sleep with the Pod 4 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF for $350 off at eightsleep.com/theproof. Try it risk-free for 30 days, with worldwide shipping.EimeleEimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Follow [this link](https://eimele.com/essential-8/15660280.html.) for 20% off one-time purchases and subscriptions.WHOOPWhoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon.Simon Hill, MSc, BSc (Hons)• Creator of theproof.com• Host of The Proof with Simon Hill• Author of The Proof is in the PlantsSubscribe & Connect:• YouTube• Apple Podcasts• Spotify• Instagram: @simonhill• Twitter: @theproof• Facebook: The Proof with Simon HillNourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.

Are seed oils actually harmful? Or is this just another wellness myth gone viral?In this episode, I sit down with Dr. Bill Harris - leading expert on dietary fats - to unpack the science on linoleic acid, an omega-6 fat found in nuts, seeds, and vegetable oils. We explore the rise of seed oil fear-mongering, the truth about inflammation, cholesterol, oxidation, and why outcome data—not mechanisms—should guide our thinking. Omega-6 Fats and Health Overview (00:00) Why the Review Was Updated (01:22) What Is Linoleic Acid? (06:47) Linoleic Intake Over Time & Health Links (12:45) Research Methods and Key Evidence (16:25) Omega-6 and Inflammation Explained (41:00) Common Myths About Seed Oils (44:37) The Oxidation Concern with Seed Oils (49:20) Omega-6 vs Omega-3: The Real Story (53:39) Blood Sugar, Insulin & Linoleic Acid (01:03:48) Heart Health and Linoleic Benefits (01:05:44) Cancer Risk and Seed Oils (01:13:49) Public Health and Future Research (01:16:55) How to Use Vegetable Oils Wisely (01:25:17) Wrap-Up and Takeaway Advice (01:32:22) If you’ve been confused by the seed oil debate, this one’s for you.Visit The Proof website for the full show notes and supporting studies.Want to support the show?The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family.This episode is brought to you by:38TERAConsider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout.Function HealthTrack, optimise, and thrive with Function Health. Access 100+ lab tests – five times more than a typical physical – including ApoB and LP(a), no doctor approval needed. Get science-backed insights and track your results over time. Skip the 400,000-person waitlist at functionhealth.com/simonhill. Only available to those living in the United States.Eight SleepUpgrade your sleep with the Pod 4 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF for $350 off at eightsleep.com/theproof. Try it risk-free for 30 days, with worldwide shipping.EimeleEimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to [Eimele.com](https://eimele.com/essential-8/15660280.html.) and use code SIMON at checkout for 10% off your first order.WHOOPWhoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon.Simon Hill, MSc, BSc (Hons)• Creator of theproof.com• Host of The Proof with Simon Hill• Author of The Proof is in the PlantsSubscribe & Connect:• YouTube• Apple Podcasts• Spotify• Instagram: @simonhill• Twitter: @theproof• Facebook: The Proof with Simon HillNourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.

In today’s episode, I’m joined by Drew Harrisberg, an exercise physiologist, diabetes educator, and founder of Drew’s Daily Dose.We dive into the science behind Apple Cider Vinegar (ACV)—does it actually help with blood sugar, weight loss, digestion, and overall health, or is it just another overhyped wellness trend?We also explore the power of anecdotes in the wellness industry, starting with Belle Gibson’s story and the new Netflix series on ACV. How can we separate fact from fiction when faced with bold health claims on social media?What we cover:• ACV and blood sugar – does it really help?• ACV and weight loss – what does the science say?• ACV vs. other blood sugar strategies (walking, fiber, etc.)• Potential downsides – acid, teeth damage, capsules, and more• How to take ACV without ruining your teeth• Should Simon take Bragg’s ACV as a sponsor? Ethics of podcast adsLater, Drew shares a moving tribute to his dog, Dennis, reflecting on grief, love, and celebrating life. We also talk about memory dividends and why showing up for the people (and pets) we love matters.We wrap up with a shocking magic trick, plenty of laughs, and a classic dad joke.Want to support the show?The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family.This episode is brought to you by:38TERAConsider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout.MomentousMy go-to supplement brand for protein and creatine is Momentous. Get 20% off your first purchase by using the code LIVINGPROOF at checkout at livemomentous.comBirchSleep deeply and wake up refreshed with a Birch Natural Mattress, combining premium natural materials with unbeatable comfort. Rest easy with a 100-night trial and 25-year warranty. Get 20% off sitewide and 2 free Eco-Rest Pillows at birchliving.com/simonhill.EimeleEimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Follow [this link](https://eimele.com/essential-8/15660280.html.) for 20% off one-time purchases and subscriptions.WHOOPWhoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon.Simon Hill, MSc, BSc (Hons)• Creator of theproof.com• Host of The Proof with Simon Hill• Author of The Proof is in the PlantsSubscribe & Connect:• YouTube• Apple Podcasts• Spotify• Instagram: @simonhill• Twitter: @theproof• Facebook: The Proof with Simon HillNourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.

This episode originally aired on The Adversity Advantage, hosted by Doug Bopst—a personal trainer, author, and former addict who transformed his life through fitness. His podcast dives deep into health, mindset, and resilience to help people unlock their full potential.In our conversation, we break down the science of longevity, nutrition, and optimal health. We discuss the best dietary patterns for longevity, the debate around red meat and seed oils, and why exercise is essential for long-term health.Topics Covered: What does the science say about longevity and diet? Are seed oils really harmful, or is the science misunderstood? The real risks of red meat and saturated fats for long-term health How ultra-processed foods impact metabolic health The importance of protein intake for longevity and muscle preservation Why exercise is just as crucial as diet for healthspan The Living Proof Challenge – a zero-cost 12-week longevity program Join the Living Proof Challenge: theproof.com/livingproofYou can connect with Doug through his Podcast Website, where he shares insightful conversations on health, fitness, and personal transformation. Follow him on Instagram for daily inspiration and expert advice, subscribe to his YouTube channel for in-depth discussions and interviews, and stay updated with his latest thoughts on X. Introduction (00:00) Discussing the Best Dietary Patterns for Longevity (00:53) Debating Meat-Based Diets and Long-Term Health (04:33) Health Implications of Red Meat Consumption (09:54) Practical Steps for Improved Health & Longevity (22:50) Understanding Amino Acids and Protein Sources (34:01) The Importance of Exercise for Longevity (34:50) Exercise Protocols for Optimal Health (35:47) Resistance Training and Its Benefits (37:43) Cardio and Resistance Training Balance (41:30) Intermittent Fasting and Meal Timing (52:40) The Role of Light and Circadian Rhythms (56:20) Insights on Longevity and Nutrition (59:47) The Importance of Relationships for Happiness (01:04:01) Conclusion (01:09:17) Want to support the show?The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family.This episode is brought to you by:38TERAConsider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout.Function HealthTrack, optimise, and thrive with Function Health. Access 100+ lab tests – five times more than a typical physical – including ApoB and LP(a), no doctor approval needed. Get science-backed insights and track your results over time. Skip the 400,000-person waitlist at functionhealth.com/simonhill. Only available to those living in the United States.ShopifyShopify, the world's leading e-commerce platform, helps you turn browsers into buyers with the internet’s best-converting check out–up to 36% better compared to other leading e-commerce platforms. To boost your conversion rate, and grow your business, sign up for a one-dollar-per-month trial period at shopify.com/proof.Simon Hill, MSc, BSc (Hons)• Creator of theproof.com• Host of The Proof with Simon Hill• Author of The Proof is in the PlantsSubscribe & Connect:• YouTube• Apple Podcasts• Spotify• Instagram: @simonhill• Twitter: @theproof• Facebook: The Proof with Simon HillNourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.

You may have heard claims that C15:0 (pentadecanoic acid) is the first essential fat discovered in 90 years, a powerful longevity booster, and a game-changer for metabolic health. But how much of this is backed by solid science?In this episode, I sit down with Dr. Bill Harris, a leading expert in fatty acid research, to critically evaluate the evidence behind C15:0. We break down the population studies linking it to health benefits, the key clinical trials testing its effects, and whether the marketing around Fatty15 is ahead of the actual data.In this episode, we cover: What exactly is C15:0, and how does it compare to other fats? The claim that C15:0 is an essential nutrient—does it meet the criteria? The current evidence on C15:0 and its impact on cholesterol, glucose, and inflammation Does C15:0 supplementation mimic omega-3s, metformin, or rapamycin? The broader issue of patenting a naturally occurring compound For more details and supporting studies, visit the full show notes. Introduction to Pentadecanoic Acid (C15:0) (00:00) Evaluating the Claims of C15:0 (02:05 Comparing C15:0 with Other Fatty Acids (03:12) Health Implications of Dairy Fats and the Essentiality of C15:0 (05:02) Scientific Evidence and Studies on C15:0 (13:12) Interpreting Clinical Trial Results, Cholesterol, and the Tango Trial (27:59) Cholesterol and the Tango Trial (28:28) Comparing C15:0 to Omega 3s (32:02) Future Research Directions for C15:0 (37:46) Longevity Claims and Patents (42:30) Final Thoughts and Conclusion (49:44) Want to support the show?The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family.This episode is brought to you by:38TERAConsider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Eight SleepUpgrade your sleep with the Pod 4 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF for $350 off at eightsleep.com/theproof. Try it risk-free for 30 days, with worldwide shipping.EimeleEimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Follow this link for 20% off one-time purchases and subscriptions.WHOOPWhoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon.Simon Hill, MSc, BSc (Hons)• Creator of theproof.com• Host of The Proof with Simon Hill• Author of The Proof is in the PlantsSubscribe & Connect:• YouTube• Apple Podcasts• Spotify• Instagram: @simonhill• Twitter: @theproof• Facebook: The Proof with Simon HillNourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.

Is olive oil really as healthy as people claim? How does it compare to other fats? And how do you choose the best product for cooking and everyday use?In this episode, I take a deep dive into the science behind olive oil—its potential role in longevity, its impact on chronic diseases like cardiovascular disease and diabetes, and the key factors that determine quality.In this episode, we cover: Olive oil’s role in longevity and overall health The difference between refined and extra virgin olive oil How olive oil may influence cardiovascular, cognitive, and metabolic health What to look for when buying olive oil and how to store it properly Whether it’s safe to cook with olive oil and how to preserve its benefits For more details and supporting studies, visit the full show notes. Introduction (00:00) Olive Oil for Longevity and Lifespan (00:52) Olive Oil for Heart Health and Chronic Disease (06:28) Olive Oil’s Role in Cancer Prevention (07:58) Olive Oil for Brain Health and Cognitive Function (12:38) Olive Oil for Metabolic Health and Blood Sugar Control (16:08) How Olive Oil Supports Overall Health (21:12) How to Choose High-Quality Olive Oil (25:27) Best Practices for Cooking and Storing Olive Oil (35:12) Key Takeaways on Olive Oil’s Health Benefits (41:32) Want to support the show?The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family.This episode is brought to you by:38TERAConsider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Function HealthTrack, optimise, and thrive with Function Health. Access 100+ lab tests – five times more than a typical physical – including ApoB and LP(a), no doctor approval needed. Get science-backed insights and track your results over time. Skip the 400,000-person waitlist at functionhealth.com/simonhill. Only available to those living in the United States.Pique TeaPique's Nandaka provides sustainable, all-day energy and makes you feel like you’re doing something good for your body! Try Pique and get 20% off plus a FREE starter kit when you shop exclusively at Piquelife.com/simon.CalmFind your calm anytime, anywhere with Calm, the #1 app for meditation and relaxation. From guided meditations to sleep stories and breathing exercises, Calm helps you reduce stress, improve focus, and sleep better. Visit calm.com/proof for 40% off a premium subscription today.Applied Nutrition LiteracyLooking to sharpen your nutrition literacy and make smarter, science-based decisions? Enrol in the Applied Nutrition Literacy Course to gain the tools you need to evaluate research confidently. Perfect for nutrition professionals and keen enthusiasts. Join by March 8 here.EimeleEimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Follow this link for 20% off one-time purchases and subscriptions.WHOOPWhoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon.Simon Hill, MSc, BSc (Hons)• Creator of theproof.com• Host of The Proof with Simon Hill• Author of The Proof is in the PlantsSubscribe & Connect:• YouTube• Apple Podcasts• Spotify• Instagram: @simonhill• Twitter: @theproof• Facebook: The Proof with Simon HillNourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.