New Books in Big Ideas

Can experimenting with game design increase our chances of finding a cure for cancer? Cancer is crafty, forcing us to be just as clever in our efforts to outfox it—and we’ve made excellent progress, but is it time for a new play in the playbook? In Gaming Cancer: How Building and Playing Video Games Can Accelerate Scientific Discovery (MIT Press, 2025), Jeff Yoshimi proposes a new approach to fighting an increasingly exhausting war. By putting the work of cancer research into the hands of nonspecialists, Yoshimi believes, we can accelerate the process of outgaming the disease once and for all. Gamers have already used “serious games” to discover new galaxies, digitize ancient texts, decode viruses, and solve theoretical problems in neuroscience. Cancer is a multilayered threat, and our best bet at overcoming it is via more minds working in concert. Gaming Cancer is an instruction manual for engineering games that motivate users to strain and sweat to find cancer cures. It integrates game design with research in cancer biology, data visualization techniques, and developments in cognitive science and AI while remaining sensitive to the limitations of citizen science and ethical concerns. Yoshimi sees in cutting-edge game technology the potential to educate and empower people to outwit cancer, an indirect route to richer science literacy that draws on the boundless resources of the mind. This book offers anyone invested in beating this seemingly intractable disease a concrete playbook that combines real science with creative vision in an effort to defeat the boss monster, cancer.Rudolf Thomas Inderst (*1978) enjoys video games since 1985. He received a master’s degree in political science, American cultural studies as well as contemporary and recent history from Ludwig-Maximilians-University, Munich and holds two PhDs in game studies (LMU & University of Passau). Currently, he's teaching as a professor for game design at the IU International University for Applied Science, has submitted his third dissertation at the University of Vechta, holds the position as lead editor at the online journal Titel kulturmagazin for the game section, hosts the German local radio show Replay Value and is editor of the weekly game research newsletter DiGRA D-A-CH Game Studies Watchlist. Learn more about your ad choices. Visit megaphone.fm/adchoicesSupport our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/big-ideas

Of all the mental illnesses, schizophrenia eludes us the most. No matter the strides scientists have made in neurological research nor doctors have made in psychiatric treatment, schizophrenia remains misunderstood, almost complacently mythologized. Without a reason for the illness, patients feel even more alienated than they already do, families are left hopeless, and doctors struggle to provide accurate care. Steven Lesk, though, after a medical career dedicated to those affected by schizophrenia and a determination to find the answer to its existence, presents a groundbreaking theory that will forever change the lives of the mentally ill. In Footprints of Schizophrenia: The Evolutionary Roots of Madness (Prometheus, 2023), Lesk threads evolutionary evidence with neurological evidence, turning the mysteries of our minds into a tapestry of logic. With his breakthrough theory and this unprecedented book, Lesk will invite necessary cultural dialogue about this stigmatized illness, provoke new psychiatric and pharmacological research, and provide unequivocal comfort to those afflicted and affected by schizophrenia.Lesk's "primitive organization theory" is based in human evolution, from Neanderthals to Homo sapiens, and the specific changes to our brains after the emergence of language. We have existed in human-like form for six million years, but we've only had language for 50,000; within the vast span of evolutionary time, that's hardly any time at all. Lesk elucidates us to the hormones affected by language, especially dopamine, and with brilliant clarity, connects human evolution, our brain affected by language, and those with schizophrenia whose dopamine doesn't flow in our new, adaptive way. In other words, the twenty million people who have schizophrenia in the world don't suppress dopamine in the way evolution has trained us, so their brains don't process language well and function as if they're in a hallucinatory, delusional dream state. Not only will Lesk's theory focus treatment efforts for schizophrenia, but it will also affect that of other dopamine-related mental illnesses like Alzheimer's, Parkinson's, Huntington's chorea, Tourette's, ADD, and more. Publishing Lesk's work will usher in a new era of psychiatric understanding, one that the field and the public desperately needs. Learn more about your ad choices. Visit megaphone.fm/adchoicesSupport our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/big-ideas

In this episode of Madison's Notes, Jonathan Haidt, renowned social psychologist and author, dives deep into the impact of digital saturation on today's youth, drawing insights from his latest book, The Anxious Generation: How the Great Rewiring of Childhood Is Causing an Epidemic of Mental Illness (Allen Lane, 2024). The discussion explores how growing up immersed in social media, video games, and smart technology is reshaping young people’s sense of self and influencing their political engagement. Haidt explains how the constant connectivity may be contributing to an increase in anxiety and how it’s altering their approach to both personal identity and societal participation.Haidt also addresses the potential for a "generational war," where differences between older and younger generations are often framed as inherent character flaws. He emphasizes the importance of understanding that many of Gen Z’s choices have been shaped by forces beyond their control, rather than pointing to a moral failing. This leads into a comparison with the themes explored in The Coddling of the American Mind, particularly the societal impact of overprotection and the lack of resilience-building among youth.The conversation then moves into practical territory, with Haidt discussing the importance of activating the brain’s inhibition system to help young people develop resilience and the ability to handle stress, conflict, and complex decision-making. He suggests that cultivating the inhibition system through thoughtful practices is key in fostering more resilient and independent young adults.Finally, Haidt examines the role of tech giants like Elon Musk and Mark Zuckerberg in shaping the digital landscape and their growing political influence. He discusses the challenges of addressing the negative impacts of social media, pondering whether government intervention will result in meaningful change or if the influence of tech leaders will prevent any real reform.This episode provides a compelling exploration of how technology, societal norms, and political dynamics intersect to shape the lives of younger generations and offers valuable insight into the challenges and opportunities that lie ahead for both youth and society at large.Madison’s Notes is the podcast of Princeton University’s James Madison Program in American Ideals and Institutions.Contributions to and/or sponsorship of any speaker does not constitute departmental or institutional endorsement of the specific program, speakers or views presented. Learn more about your ad choices. Visit megaphone.fm/adchoicesSupport our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/big-ideas

Many people assume that the first introduction of Christianity to the Chinese was part of nineteenth-century Western imperialism. In fact, Syriac-speaking Christians brought the gospel along the Silk Road into China in the seventh century. Glen L. Thompson introduces readers to the fascinating history of this early Eastern church, referred to as Jingjiao, or the “Luminous Teaching.”Thompson presents the history of the Persian church’s mission to China with rigor and clarity. While Christianity remained a minority and “foreign” religion in the Middle Kingdom, it nonetheless attracted adherents among indigenous Chinese and received imperial approval during the Tang Dynasty. Though it was later suppressed alongside Buddhism, it resurfaced in China and Mongolia in the twelfth century. Thompson also discusses how the modern unearthing of Chinese Christian texts has stirred controversy over the meaning of Jingjiao to recent missionary efforts in China.In an accessible style, Thompson guides readers through primary sources as well as up-to-date scholarship. As the most recent and balanced survey on the topic available in English, Jingjiao: The Earliest Christian Church in China (Eerdmans, 2024) will be an indispensable resource for students of global Christianity and missiology.Glen L. Thompson is professor emeritus of New Testament and historical theology at Asia Lutheran Seminary in Hong Kong. He has retired to Milwaukee, where he researches, works with students, and expands his Fourth-Century Christianity website.New Books in Syriac Studies is presented by Kristian Heal. Learn more about your ad choices. Visit megaphone.fm/adchoicesSupport our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/big-ideas

Ada Palmer joins Jana Byars to talk about her new book, Inventing the Renaissance (U Chicago Press, 2025) and the ways history is written and used. From the darkness of a plagued and war-torn Middle Ages, the Renaissance (we’re told) heralds the dawning of a new world—a halcyon age of art, prosperity, and rebirth. Hogwash! or so says award-winning novelist and historian Ada Palmer. In Inventing the Renaissance, Palmer turns her witty and irreverent eye on the fantasies we’ve told ourselves about Europe’s not-so-golden age, myths she sets right with sharp clarity.Palmer’s Renaissance is altogether desperate. Troubled by centuries of conflict, she argues, Europe looked to a long-lost Roman Empire (even its education practices) to save them from unending war. Later historians met their own political challenges with a similarly nostalgic vision, only now they looked to the Renaissance and told a partial story. To right this wrong, Palmer offers fifteen provocative portraits of Renaissance men and women (some famous, some obscure) whose lives reveal a far more diverse, fragile, and wild Renaissance than its glowing reputation suggests. Learn more about your ad choices. Visit megaphone.fm/adchoicesSupport our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/big-ideas

For millennia, land has been a symbol of wealth and privilege. But the true power of land ownership is even greater than we might think. In Land Power: Who Has It, Who Doesn't, and How That Determines the Fate of Societies (Basic Books, 2025), political scientist Michael Albertus shows that who owns the land determines whether a society will be equal or unequal, whether it will develop or decline, and whether it will safeguard or sacrifice its environment.Modern history has been defined by land reallocation on a massive scale. From the 1500s on, European colonial powers and new nation-states shifted indigenous lands into the hands of settlers. The 1900s brought new waves of land appropriation, from Soviet and Maoist collectivization to initiatives turning large estates over to family farmers. The shuffle continues today as governments vie for power and prosperity by choosing who should get land. Drawing on a career’s worth of original research and on-the-ground fieldwork, Albertus shows that choices about who owns the land have locked in poverty, sexism, racism, and climate crisis—and that what we do with the land today can change our collective fate.Michael Albertus is professor of political science at the University of Chicago. The author of four previous books, his writing has appeared in the New York Times, Washington Post, Atlantic, Foreign Affairs, and elsewhere. He lives in Chicago, Illinois. Learn more about your ad choices. Visit megaphone.fm/adchoicesSupport our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/big-ideas

Misery beneath the Miracle in East Asia (Cornell University Press, 2024) challenges prevailing views of the East Asian economic miracle. Existing scholarship has overlooked the severity, persistence, and harmful consequences of the social-welfare crises affecting the region. Dr. Arvid J. Lukauskas and Dr. Yumiko Shimabukuro fill this gap and put a major asterisk on East Asia's economic record.Combining big-picture analysis, abundant data, a dynamic interdisciplinary framework, and powerful human stories, they shed light on the social ills that governments have failed to address adequately, including low wages, child abuse, elderly poverty, and substandard housing. One of the major forces behind the multidimensional welfare crises is the region's productivist welfare strategy, which prioritizes economic growth while abandoning a robust social safety net, leaving the most vulnerable segments of society largely unprotected.Misery beneath the Miracle in East Asia brings the region into debates over the dangers of seeking growth at all costs that are currently embroiling the United States and other advanced industrialized countries.This interview was conducted by Dr. Miranda Melcher whose new book focuses on post-conflict military integration, understanding treaty negotiation and implementation in civil war contexts, with qualitative analysis of the Angolan and Mozambican civil wars. Learn more about your ad choices. Visit megaphone.fm/adchoicesSupport our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/big-ideas

We often think of the modern era as the age of American power. In reality, we’re living in a long, violent Eurasian century. That giant, resource-rich landmass possesses the bulk of the global population, industrial might, and potential military power; it touches all four of the great oceans. Eurasia is a strategic prize without equal―which is why the world has been roiled, reshaped, and nearly destroyed by clashes over the supercontinent.Since the early twentieth century, autocratic powers―from Germany under Kaiser Wilhelm II to the Soviet Union―have aspired for dominance by seizing commanding positions in the world’s strategic heartland. Offshore sea powers, namely the United Kingdom and America, have sought to make the world safe for democracy by keeping Eurasia in balance. America’s rivalries with China, Russia, and Iran are the next round in this geopolitical game. If this new authoritarian axis succeeds in enacting a radically revised international order, America and other democracies will be vulnerable and insecure.In The Eurasian Century: Hot Wars, Cold Wars, and the Making of the Modern World (W. W. Norton & Company, 2025) Hal Brands, a renowned expert on global affairs, argues that a better understanding of Eurasia’s strategic geography can illuminate the contours of rivalry and conflict in today’s world. The Eurasian Century explains how revolutions in technology and warfare, and the rise of toxic ideologies of conquest, made Eurasia the center of twentieth-century geopolitics―with pressing implications for the struggles that will define the twenty-first.Hal Brands, coauthor of Danger Zone: The Coming Conflict with China, is the Henry Kissinger Distinguished Professor at the Johns Hopkins University School of Advanced International Studies, senior fellow at the American Enterprise Institute, and a columnist for Bloomberg Opinion. He lives in Bethesda, Maryland.Stephen Satkiewicz is an independent scholar whose research areas are related to Civilizational Sciences, Social Complexity, Big History, Historical Sociology, military history, War studies, International Relations, Geopolitics, as well as Russian and East European history. Learn more about your ad choices. Visit megaphone.fm/adchoicesSupport our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/big-ideas

AI psychiatrists promise to detect mental disorders with superhuman accuracy, provide affordable therapy for those who can't afford or can't access treatment, and even invent new psychiatric drugs. But the hype obscures an unnerving reality. In The Silicon Shrink: How Artificial Intelligence Made the World an Asylum (MIT Press, 2025), Daniel Oberhaus tells the inside story of how the quest to use AI in psychiatry has created the conditions to turn the world into an asylum. Most of these systems, he writes, have vanishingly little evidence that they improve patient outcomes, but the risks they pose have less to do with technological shortcomings than with the application of deeply flawed psychiatric models of mental disorder at unprecedented scale.Oberhaus became interested in the subject of mental health after tragically losing his sister to suicide. In The Silicon Shrink, he argues that these new, ostensibly therapeutic technologies already pose significant risks to vulnerable people, and they won't stop there. These new breeds of AI systems are creating a psychiatric surveillance economy in which the emotions, behavior, and cognition of everyday people are subtly manipulated by psychologically savvy algorithms that have escaped the clinic. Oberhaus also introduces readers to the concept of “swipe psychology,” which is quickly establishing itself as the dominant mode of diagnosing and treating mental disorders.It is not too late to change course, but to do so means we must reckon with the nature of mental illness, the limits of technology, and what it means to be human.This interview was conducted by Dr. Miranda Melcher whose new book focuses on post-conflict military integration, understanding treaty negotiation and implementation in civil war contexts, with qualitative analysis of the Angolan and Mozambican civil wars. Learn more about your ad choices. Visit megaphone.fm/adchoicesSupport our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/big-ideas

Artificial Intelligence fuels both enthusiasm and panic. Technologists are inclined to give their creations leeway, pretend they’re animated beings, and consider them efficient. As users, we may complain when these technologies don’t obey, or worry about their influence on our choices and our livelihoods. And yet, we also yearn for their convenience, see ourselves reflected in them, and treat them as something entirely new. But when we overestimate the automation of these tools, award-winning author Antonio A. Casilli argues, we fail to recognize how our fellow humans are essential to their efficiency. The danger is not that robots will take our jobs, but that humans will have to do theirs.In this bracing and powerful book, Antonia A. Casilli uses up-to-the-minute research to show how today’s technologies, including AI, continue to exploit human labor—even ours. He connects the diverse activities of today’s tech laborers: platform workers, like Uber drivers and Airbnb hosts; “micro workers,” including those performing atomized tasks like data entry on Amazon Mechanical Turk; and the rest of us, as we evaluate text or images to show we’re not robots, react to Facebook posts, or approve or improve the output of generative AI. As Casilli shows us, algorithms, search engines, and voice assistants wouldn’t function without unpaid or underpaid human contributions. Further, he warns that if we fail to recognize this human work, we risk a dark future for all human labor.Waiting for Robots: The Hired Hands of Automation (U Chicago Press, 2025) urges us to move beyond the simplistic notion that machines are intelligent and autonomous. As the proverbial Godot, robots are the bearers of a messianic promise that is always postponed. Instead of bringing prosperity for all, they discipline the workforce, so we don’t dream of a world without drudgery and exploitation. Casilli’s eye-opening book makes clear that most “automation” requires human labor—and likely always will—shedding new light on today’s consequences and tomorrow’s threats of failing to recognize and compensate the “click workers” of today.Michael O. Johnston, Ph.D. is a Assistant Professor of Sociology at William Penn University. He is the author of The Social Construction of a Cultural Spectacle: Floatzilla (Lexington Books, 2023) and Community Media Representations of Place and Identity at Tug Fest: Reconstructing the Mississippi River (Lexington Books, 2022). His general area of study is at the intersection of space, behavior, and identity. He is currently conducting research about the negotiation that humans make between oneself, identification of place, and the attachment/s they have to those places. To learn more about Michael O. Johnston you can go to his personal website, Google Scholar, Bluesky (@professorjohnst.bsky.social),Twitter (@ProfessorJohnst), or by email (johnstonmo@wmpenn.edu) Learn more about your ad choices. Visit megaphone.fm/adchoicesSupport our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/big-ideas