VJHemOnc Podcast
VJHemOnc
The Video Journal of Hematological Oncology (VJHemOnc) podcast covers the latest hematological oncology and hematology news from international experts – from leukemias, lymphomas, MDS and MPNs, to sickle cell, aplastic anemia and rare diseases. Made for healthcare professionals and researchers, we are a global, independent, open-access platform. Listen to the latest news, including cutting-edge trial updates, controversies and opinion. If you enjoy the podcast, please leave us a rating and review! For more news visit www.vjhemonc.com
Episodes
Mentioned books
Sep 8, 2023 • 11min
Applications of MRD in multiple myeloma: using MRD to guide treatment decisions
Meral Beksac and Luciano Costa discuss the applications of MRD in multiple myeloma and its potential to guide treatment decisions. They delve into the importance of achieving and sustaining MRD negativity for better patient outcomes. They also explore the impact of maintenance therapy and the potential of using MRD as a surrogate marker in clinical trials to accelerate drug development.
Aug 23, 2023 • 9min
Exploring and comparing the curative potential of CAR-T therapy & bispecific antibodies in R/R DLBCL
Explore the curative potential of CAR-T therapy and bispecific antibodies in R/R DLBCL. Learn about the benefits and drawbacks of these agents, their efficacy, and curative potential. Compare CAR-T therapy and bispecific antibodies in relapsed refractory DLBCL, including data, toxicity profiles, accessibility, and price considerations. Highlight the more mature data and longer follow-up of CAR-T cell therapy and the survival advantage in the second-line setting.
Aug 16, 2023 • 10min
Pre-MDS states: improving prognosis, novel therapeutic approaches, and challenges with distinguishing these conditions
Experts discuss the challenges of diagnosing pre-MDS states and distinguishing them from MDS. They explore advancements in genetics and AI for improved classification and prognosis. Strategies for improved diagnosis include flow cytometry and AI-based approaches. Treatment options for clone hematopoiesis and clone cytopenias are also explored, including targeted substances and anti-interlucine one-beta antibody.
Aug 10, 2023 • 8min
Accelerated-phase MPNs: mutational landscape, challenges, and novel treatment strategies being explored
Experts discuss the mutational landscape and challenges of treating accelerated-phase myeloproliferative neoplasms (MPNs). They highlight the need for novel treatment strategies, including targeted and combination therapies, to improve outcomes.
Aug 3, 2023 • 7min
Determining the optimal sequencing of bispecifics and CAR-T cells in multiple myeloma
Experts Salomon Manier, Surbhi Sidana, and Hermann Einsele discuss the optimal sequencing of bispecific antibodies and CAR-T cells in multiple myeloma, highlighting data from recent clinical trials. They explore mechanisms of resistance, factors to consider when sequencing, and potential sequencing strategies, recommending CAR-T cell therapy followed by bispecific antibodies based on emerging data.
Jul 27, 2023 • 11min
Overcoming barriers to CAR-T therapy: improving access and cost
Edward Cliff from Brigham and Women's Hospital and Natacha Bolaños, Lymphoma Coalition Europe, discuss two major barriers to CAR-T therapy: the high cost and the need to improve access. They explore strategies to reduce costs and ensure global accessibility while prioritizing patient preferences and shared decision making.
Jul 19, 2023 • 6min
The importance of addressing quality of life and improving symptom management in MPNs
In this podcast, Ruben Mesa, MD along with other experts discuss the importance of addressing quality of life and improving symptom management in patients with myeloproliferative neoplasms (MPNs). They highlight the impact of symptoms on patients' quality of life and the potential benefits of novel treatments like JAK inhibitors, meditation, yoga, and dietary changes.
Jul 11, 2023 • 9min
Updates in the treatment and management of amyloidosis and the importance of the multidisciplinary team
Experts discuss updates in the treatment and management of amyloidosis, including accurate diagnosis, different treatment strategies, and the potential of new drugs and monoclonal antibodies. They also highlight the importance of a multidisciplinary team in managing complications and symptoms of amyloidosis.
Jul 5, 2023 • 7min
Hemophilia: the current standard of care and the value of novel gene therapies
Listen to Michiel Coppens, an expert in hemophilia treatment and research, as he discusses the limitations of factor replacement therapy and the potential of novel gene therapies using AAV. Find out about the successful phase three trial results for hemophilia A and B and the current status of AAV-based gene therapy for hemophilia.
Jun 29, 2023 • 14min
CLL highlights at EHA 2023: latest advances with the use of BTK inhibitors
Leading expert in hematological oncology Lydia Scarfò discusses the latest updates with the use of BTK inhibitors in CLL. Topics addressed include the management of double-refractory patients, the efficacy and toxicity of covalent and non-covalent BTK inhibitors, and the sequencing of these agents.
