No One Saw It Coming

Dr. Eugene Helveston, a former pediatric ophthalmologist and author, shares his fascinating journey with botulinum toxin— from its origins as a deadly poison linked to food poisoning to a billion-dollar beauty treatment known as Botox. He discusses pioneering experiments that first used the toxin to treat eye spasms and highlights the daring innovations that led to its cosmetic popularity. The conversation also explores Botox's medical applications, showcasing how one man's vision transformed a lethal substance into a life-changing medical marvel.

Dr. Tatiana Burr, an ancient Greek cultural historian, dives into the captivating story of the Antikythera mechanism, hailed as the world's first computer. She shares how it was unearthed from a shipwreck by sponge divers over a century ago. The discussion covers the intricacies of its gears and functions, revealing advanced ancient engineering. Tatiana challenges the lone-genius myth, highlighting the collaboration between cultures that led to this remarkable device. Her insights transform our understanding of ancient technology and civilization.

William Dalrymple, a historian and author known for his expertise in South Asian history, dives into the captivating saga of Wu Zetian, China's first and only female emperor. He reveals her extraordinary rise from concubine to monarch, leveraging Buddhism as her secret weapon for legitimacy. Dalrymple discusses her bold maneuvers in the brutal court politics, including accusations against rivals leading to their demise. He also connects her reign to the spread of Buddhism in China while tracing its decline in India, painting a vivid picture of power, faith, and intrigue.

Cultural historian Kassia St Clair dives into the fascinating world of purple, once a royal color reserved for the elite. She shares the story of teenager William Perkin, whose lab accident led to the creation of synthetic purple dye, forever changing fashion. Kassia reveals how Perkin's invention sparked a cultural revolution and made color accessible to everyone, along with purple's evolving meanings, from royalty to modern symbols of identity. Tune in for a captivating journey through history and chemistry!

There’s that phrase a picture says a thousand words... but what does a picture of child labour say? Curator, educator, and photo-historian Beth Saunders (University of Maryland, Baltimore County) sits down with Marc Fennell (Stuff The British Stole) to tell the story of photographer Lewis Hine and his photographs of children working in places like factories, coal mines and cotton mills in the early 1900s. His powerful photos had a lasting legacy but not in the way he expected. Binge all the episodes of No One Saw It Coming now on the ABC listen app (Australia) or wherever you get your podcasts.Get in touch:Got a story for us? We'd love to hear from you! Email us at noonesawitcoming@abc.net.au

It’s small enough to fit in your pocket and it’s saved countless lives.The asthma puffer has had a long journey, stretching back thousands of years to various treatments including asthma cigarettes. But the asthma puffer as we know it today is all thanks to a young girl’s throwaway comment over breakfast in the 1950s. Dr Daniel Duke from Monash University tells Marc Fennell (Stuff The British Stole) about how the asthma puffer came into existence and how he fits into its long history as well. Binge all the episodes of No One Saw It Coming now on the ABC listen app (Australia) or wherever you get your podcasts.Get in touch:Got a story for us? We'd love to hear from you! Email us at noonesawitcoming@abc.net.au

London, 1854. A mysterious and deadly illness is sweeping through Soho, and people are dropping like flies. The leading theory? “Bad air.” But one doctor isn’t convinced. John Snow begins to trace the outbreak — not through symptoms, but through streets. Journalist and author Sandra Hempel tells Marc Fennell (Stuff The British Stole) the story of how a hand-drawn map, a pub, and a pump sparked the birth of epidemiology — and changed the way we fight disease forever.Binge all the episodes of No One Saw It Coming now on the ABC listen app (Australia) or wherever you get your podcasts.Get in touch:Got a story for us? We'd love to hear from you! Email us at noonesawitcoming@abc.net.au

A Changi prisoner of war. A fridge full of urine. A handful of dead guinea pigs. And one of the most important medical breakthroughs of the 20th century.Greg de Moore, Associate Professor of Psychiatry based at Sydney's Westmead Hospital, tells Marc Fennell (Stuff The British Stole) about the story of Australian doctor John Cade and his pioneering work in bipolar treatment. From the horrors of a Changi prison camp to a backyard shed experiment with lithium, this is the story of how science, serendipity, and sheer human determination transformed modern psychiatry.Binge all the episodes of No One Saw It Coming now on the ABC listen app (Australia) or wherever you get your podcasts.Get in touch:Got a story for us? We'd love to hear from you! Email us at noonesawitcoming@abc.net.au

Karla FC Holloway, a bioethics expert and professor at Duke University, delves into the powerful story of Henrietta Lacks, the woman behind the groundbreaking HeLa cells. They discuss the ethical injustices faced by Henrietta, including the lack of consent for her cells' use. Holloway highlights the impact of race and gender on her life and medical treatment. They also explore the miraculous advancements enabled by HeLa cells, from vaccines to cancer research, while stressing the importance of remembering Henrietta as a whole person beyond her scientific legacy.

He soared into the sky in a balloon to prove a scientific theory and landed in the world of espionage. This is a story about a man with a fabulous moustache who called himself Professor, who was accused of being the devil in the American Civil War and ended up becoming a spy in a big balloon, triggering the creation of the US Air Force. Yes, really. Matt Bevan from ABC's If You’re Listening tells Marc Fennell (Stuff The British Stole) about the early days of aerial espionage, and how he stumbled down a rabbit hole to find this story in the first place. Binge all the episodes of No One Saw It Coming now on the ABC listen app (Australia) or wherever you get your podcasts.Get in touch:Got a story for us? We'd love to hear from you! Email us at noonesawitcoming@abc.net.au