The panel explores molecular nanotechnology and its potential for compact machines to replace industrial facilities. They discuss protein design, folding, and dynamic structures. Molecular machines can automate the synthesis of other machines, bridging the gap between organic chemistry and automation.

Gus Docker hosts The Future of Life Institute podcast, which features conversations with prominent researchers, policy experts, philosophers, and influential thinkers of all kinds. Gus studied philosophy and computer science at the University of Copenhagen and is active in Effective Altruism Denmark.Despite the ongoing threat of existential risks from AI, Gus discusses his excitement about the future's potential. He acknowledges the difficulty in envisioning the far future's technological changes, comparing the gap to that between the Stone Age and today – however, he remains excited about technologies enabling diverse experiences and consciousness exploration. Optimistic, Gus foresees a major positive shift in mental health, where individuals easily manage and enhance their mental well-being, harmonizing happiness and productivity, thus contributing to societal welfare.Full transcript, list of resources, and art piece: https://www.existentialhope.com/podcastsExistential Hope was created to collect positive and possible scenarios for the future so that we can have more people commit to creating a brighter future, and to begin mapping out the main developments and challenges that need to be navigated to reach it. Existential Hope is a Foresight Institute project.Hosted by Allison Duettmann and Beatrice ErkersFollow Us: Twitter | Facebook | LinkedIn | Existential Hope InstagramExplore every word spoken on this podcast through Fathom.fm. Hosted on Acast. See acast.com/privacy for more information.

Dr. Scott Hubbard has been a leader in space exploration for almost 50 years. His career includes a National Lab, a start-up venture, NASA, and Stanford. At NASA, Dr. Hubbard is best known as Director of NASA’s Ames Research Center, the first Mars Program Director (aka the "Mars Czar"), and the founder of NASA's Astrobiology Institute.Key HighlightsHubbard shared his deep passion for Mars and recounted his role in restructuring the Mars program.He described Mars as the most Earthlike planet, highlighting its potential for past or present life evidence.The exploration of Mars, as explained by Hubbard, focuses on life, climate, solid rock geology, and human exploration.Emphasizing the mantra "follow the water," Hubbard underscored water's essential role in supporting all known life forms.He pointed out the challenges posed by Mars' launch window, occurring every 26 months, which significantly impacts the mission's rocket science and budget.Dive deeper into the session: Full SummaryAbout Foresight InstituteForesight Institute is a research organization and non-profit that supports the beneficial development of high-impact technologies. Since our founding in 1987 on a vision of guiding powerful technologies, we have continued to evolve into a many-armed organization that focuses on several fields of science and technology that are too ambitious for legacy institutions to support.Allison DuettmannThe President and CEO of Foresight Institute, Allison Duettmann directs the Intelligent Cooperation, Molecular Machines, Biotech & Health Extension, Neurotech, and Space Programs, alongside Fellowships, Prizes, and Tech Trees. She has also been pivotal in co-initiating the Longevity Prize, pioneering initiatives like Existentialhope.com, and contributing to notable works like "Superintelligence: Coordination & Strategy" and "Gaming the Future".Get Involved with Foresight:Apply: Virtual Salons & in-person WorkshopsDonate: Support Our Work – If you enjoy what we do, please consider this, as we are entirely funded by your donations!Follow Us: Twitter | Facebook | LinkedInNote: Explore every word spoken on this podcast through Fathom.fm, an innovative podcast search engine. Hosted on Acast. See acast.com/privacy for more information.

Mark Hamalainen, cofounder of the Longevity Biotech Fellowship, shares an actionable roadmap for achieving an unlimited healthy lifespan. Topics include strategies for achieving immortality, updating the roadmap and launch strategies, comparative costs and challenges of bioengineering, whole body replacement, and cryostasis, fellowship criteria, critical aspects of longevity, and upcoming Vision Weekends.

Jason Crawford is the founder of The Roots of Progress, where he writes and speaks about the history of technology and the philosophy of progress. Previously, he spent 18 years as a software engineer, engineering manager, and startup founder.Session Summary: Jason envisages a future marked by dynamic, continuous progress, encapsulated in the concept of protopia. This vision diverges from a traditional notion of a utopia, and instead embraces a reality of constant, incremental improvement. In Jason's view, progress is an ever-evolving journey, not a destination. It's a series of small, significant steps that, over time, lead to profound transformations in our world.Central to Jason's perspective is the transformative potential of AI, paralleling historical technological leaps like the steam engine and personal computing. He views AI as a catalyst for a new era in human history, one that could redefine societal structures by making high-quality services accessible to a broader demographic. This democratization of resources, akin to services becoming as affordable as a Netflix subscription, could bridge societal gaps. However, Jason emphasizes that this protopian future requires collective agency, responsibility, and a balanced understanding of our role in shaping it. He believes that progress accelerates over time, with each innovation building upon the last, thus speeding up future advancements.Full transcript, list of resources, and art piece: https://www.existentialhope.com/podcastsExistential Hope was created to collect positive and possible scenarios for the future so that we can have more people commit to creating a brighter future, and to begin mapping out the main developments and challenges that need to be navigated to reach it. Existential Hope is a Foresight Institute project.Hosted by Allison Duettmann and Beatrice ErkersFollow Us: Twitter | Facebook | LinkedIn | Existential Hope InstagramExplore every word spoken on this podcast through Fathom.fm. Hosted on Acast. See acast.com/privacy for more information.

Casey Handmer is the founder of Terraform Industries, a company dedicated to gigascale atmospheric hydrocarbon synthesis. His method of creating hydrocarbons promises to be a cheaper and cleaner alternative to traditional oil wells.Known for his work as an astrophysicist, innovator, and Mars aficionado, Casey is eager to guide us through the intricate landscape of Martian exploration. This presentation explores the scientific, technological, and logistical hurdles that make Mars such a challenging destination. Casey offers an insider’s perspective on our journey towards making human life sustainable on Mars.Dive deeper into the session: Full SummaryAbout Foresight InstituteForesight Institute is a research organization and non-profit that supports the beneficial development of high-impact technologies. Since our founding in 1987 on a vision of guiding powerful technologies, we have continued to evolve into a many-armed organization that focuses on several fields of science and technology that are too ambitious for legacy institutions to support.Allison DuettmannThe President and CEO of Foresight Institute, Allison Duettmann directs the Intelligent Cooperation, Molecular Machines, Biotech & Health Extension, Neurotech, and Space Programs, alongside Fellowships, Prizes, and Tech Trees. She has also been pivotal in co-initiating the Longevity Prize, pioneering initiatives like Existentialhope.com, and contributing to notable works like "Superintelligence: Coordination & Strategy" and "Gaming the Future".Get Involved with Foresight:Apply: Virtual Salons & in-person WorkshopsDonate: Support Our Work – If you enjoy what we do, please consider this, as we are entirely funded by your donations!Follow Us: Twitter | Facebook | LinkedInNote: Explore every word spoken on this podcast through Fathom.fm, an innovative podcast search engine. Hosted on Acast. See acast.com/privacy for more information.

Matjaz Leonardis discusses the risks of undetectable back doors in ML models, their impact on model integrity, challenges to interpretability and robustness, and the need for deeper research into vulnerabilities.

Dr. Anders Sandberg is a Senior Research Fellow at the Future of Humanity Institute at Oxford University, where he specializes in the management of low-probability, high-impact risks and future technology capabilities. With a Ph.D. in computational neuroscience from Stockholm University, his expertise spans computer science, neuroscience, and medical engineering. A cofounder of the think tank Eudoxa and former chairman of the Swedish Transhumanist Association, Sandberg is recognized for his contributions to neuroethics, cognitive enhancement, and global catastrophic risk.Key HighlightsThe impact and growth of the mind uploading research field since its foundational workshop.The influence of the workshop's roadmap, evidenced by citations across disciplines from humanities to AI safety.The astounding advancements in biotech, signaling qualitative leaps beyond traditional tech scaling.Neurotech achievements in setting clear goals, enhancing data interoperability, and developing detailed brain structure simulations.About Foresight InstituteForesight Institute is a research organization and non-profit that supports the beneficial development of high-impact technologies. Since our founding in 1987 on a vision of guiding powerful technologies, we have continued to evolve into a many-armed organization that focuses on several fields of science and technology that are too ambitious for legacy institutions to support.Allison DuettmannThe President and CEO of Foresight Institute, Allison Duettmann directs the Intelligent Cooperation, Molecular Machines, Biotech & Health Extension, Neurotech, and Space Programs, alongside Fellowships, Prizes, and Tech Trees. She has also been pivotal in co-initiating the Longevity Prize, pioneering initiatives like Existentialhope.com, and contributing to notable works like "Superintelligence: Coordination & Strategy" and "Gaming the Future".Get Involved with Foresight:Apply: Virtual Salons & in-person WorkshopsDonate: Support Our Work – If you enjoy what we do, please consider this, as we are entirely funded by your donations!Follow Us: Twitter | Facebook | LinkedInNote: Explore every word spoken on this podcast through Fathom.fm, an innovative podcast search engine. Hosted on Acast. See acast.com/privacy for more information.

Kipply Chen is part of the data team at Anthropic.Key HighlightsThe swift pace of alignment potentially outpacing AI advancements.Challenges of coordinating predictive and base model alignment across labs.Security and policy's critical role in AI safety.A likely surge in legal issues concerning training data misuse.The push for an open-source, community-drive alignment community.Dive deeper into the session: Full SummaryAbout Foresight InstituteForesight Institute is a research organization and non-profit that supports the beneficial development of high-impact technologies. Since our founding in 1987 on a vision of guiding powerful technologies, we have continued to evolve into a many-armed organization that focuses on several fields of science and technology that are too ambitious for legacy institutions to support.Allison DuettmannThe President and CEO of Foresight Institute, Allison Duettmann directs the Intelligent Cooperation, Molecular Machines, Biotech & Health Extension, Neurotech, and Space Programs, alongside Fellowships, Prizes, and Tech Trees. She has also been pivotal in co-initiating the Longevity Prize, pioneering initiatives like Existentialhope.com, and contributing to notable works like "Superintelligence: Coordination & Strategy" and "Gaming the Future".Get Involved with Foresight:Apply: Virtual Salons & in-person WorkshopsDonate: Support Our Work – If you enjoy what we do, please consider this, as we are entirely funded by your donations!Follow Us: Twitter | Facebook | LinkedInNote: Explore every word spoken on this podcast through Fathom.fm, an innovative podcast search engine. Hosted on Acast. See acast.com/privacy for more information.

Trent McConaghy is the founder of Ocean Protocol, a decentralized platform aimed at democratizing AI data sharing while maintaining privacy. With a career starting in AI research for national defence, McConaghy transitioned to entrepreneurship, where his first startup, ADA, was acquired by Synopsys in 2004. His work continued with Solido, an AI venture aiding Moore's Law, culminating in an acquisition by Siemens in 2017. His current venture, Ocean Protocol, follows earlier initiatives like the ascribe NFT platform and BigchainDB. McConaghy's enduring mission is to equalize AI opportunities and ensure humanity's significance in a future of autonomous technology.Session SummaryThis podcast episode delves into Trent McConaghy's integration of AI with global challenges, highlighting his innovative strategies in technology and environmentalism.The Map: Trent discusses the need for a resource like Wikipedia to show potential technological outcomes – his "Starships and Tokens" outlines pathways to major goals of humanity, from superhuman intelligence to reshaping the cosmos.AI Evolution and Impact: He highlights AI's growth, especially in creative fields and CAD. Discusses AI-induced job displacement, with UBI as a potential solution. He mentions projects like Nature 2.0 for surplus wealth generation.AI Superintelligence Challenge: Focuses on keeping humans competitive with AI through high-bandwidth BCIs and addressing regulatory challenges.Climate Change Strategy: He emphasizes addressing climate change impacts on society, exploring special zones for BCI research and governance adaptations, and stresses the need for aggressive BCI development and jurisdictional arbitrage for research and climate adaptation. He also proposes a climate-focused DAO for legal actions and addressing investment risks in flood-prone areas like Miami.Vision of Eucatastrophe: Trent's long-term goals for humanity include developing Dyson spheres and achieving human superintelligence. Full transcript, list of resources, and art piece: https://www.existentialhope.com/podcastsExistential Hope was created to collect positive and possible scenarios for the future so that we can have more people commit to creating a brighter future and to begin mapping out the main developments and challenges that need to be navigated to reach it. Existential Hope is a Foresight Institute project.Hosted by Allison Duettmann and Beatrice ErkersFollow Us: Twitter | Facebook | LinkedIn | Existential Hope InstagramExplore every word spoken on this podcast through Fathom.fm. Hosted on Acast. See acast.com/privacy for more information.