“I coined the word ’eucatastrophe’: the sudden happy turn in a story which pierces you with a joy that brings tears...this is indeed how things really do work in the Great World for which our nature is made.” —JRR TolkienAvoiding existential catastrophe is a critical necessity, but so is avoiding stasis and locking in the existentially wasteful status quo. Cotton-Barratt and Ord used Tolkien’s term to suggest that ”an existential eucatastrophe is an event which causes there to be much more expected value after the event than before.” In this episode, of the podcast David Manheim, 2021 Foresight Fellow in Positive Long Term Futures and a visiting professor at the Technion focusing on long-term risks and future prospects for humanity talks about the definition of eucatastrophe, historical examples of these, increasingly dynamic civilizational stability, and much more. Music: I Knew a Guy by Kevin MacLeod is licensed under a Creative Commons Attribution 4.0 license. https://creativecommons.org/licenses/by/4.0/ Session Summary: David Manheim | Eucatastrophes & Dynamic Stability; Exploring Tensions between Risk & Opportunities - Foresight InstituteThe Foresight Institute is a research organization and non-profit that supports the beneficial development of high-impact technologies. Since our founding in 1987 on a vision of guiding powerful technologies, we have continued to evolve into a many-armed organization that focuses on several fields of science and technology that are too ambitious for legacy institutions to support.Allison Duettmann is the president and CEO of Foresight Institute. She directs the Intelligent Cooperation, Molecular Machines, Biotech & Health Extension, Neurotech, and Space Programs, Fellowships, Prizes, and Tech Trees, and shares this work with the public. She founded Existentialhope.com, co-edited Superintelligence: Coordination & Strategy, co-authored Gaming the Future, and co-initiated The Longevity Prize. Apply to Foresight’s virtual salons and in person workshops here!We are entirely funded by your donations. If you enjoy what we do please consider donating through our donation page.Visit our website for more content, or join us here:TwitterFacebookLinkedInEvery word ever spoken on this podcast is now AI-searchable using Fathom.fm, a search engine for podcasts.  Hosted on Acast. See acast.com/privacy for more information.

“I’m an active self-experimenter. I have a body, I might as well use it since it’s getting older.” Reason is the founder and writer of Fight Aging, a leading voice in the rejuvenation of biotechnology and patient advocacy communities for more than fifteen years. He is also co-founder and CEO of Repair BiotechnologiesThis episode is a Q&A on all things related to how we can fight and prevent aging with aging expert Reason. Reason works as CEO at Repair Biotechnologies, which is focused on reversing atherosclerosis. He’s also an active self-experimenter regarding aging interventions.  Reason also spearheads some aging advocacy efforts – such as the blog fightaging.org.Music: I Knew a Guy by Kevin MacLeod is licensed under a Creative Commons Attribution 4.0 license. https://creativecommons.org/licenses/by/4.0/ Session Summary: Reason, Fight Aging | Q&A on How to Fight Aging - Foresight InstituteThe Foresight Institute is a research organization and non-profit that supports the beneficial development of high-impact technologies. Since our founding in 1987 on a vision of guiding powerful technologies, we have continued to evolve into a many-armed organization that focuses on several fields of science and technology that are too ambitious for legacy institutions to support.Allison Duettmann is the president and CEO of Foresight Institute. She directs the Intelligent Cooperation, Molecular Machines, Biotech & Health Extension, Neurotech, and Space Programs, Fellowships, Prizes, and Tech Trees, and shares this work with the public. She founded Existentialhope.com, co-edited Superintelligence: Coordination & Strategy, co-authored Gaming the Future, and co-initiated The Longevity Prize. Apply to Foresight’s virtual salons and in person workshops here!We are entirely funded by your donations. If you enjoy what we do please consider donating through our donation page.Visit our website for more content, or join us here:TwitterFacebookLinkedInEvery word ever spoken on this podcast is now AI-searchable using Fathom.fm, a search engine for podcasts.  Hosted on Acast. See acast.com/privacy for more information.

“There is no physical law that can limit our life like longevity. And this is what motivates us to reach radical life extension.”Dr. Emil Kendziorra is a founder and CEO at Tomorrow Biostasis GmbH based in Berlin, Germany and President of the Board of a nonprofit research foundation in Switzerland. He has a strong background in medicine, cancer research and entrepreneurship.Aschwin de Wolf is one of the world’s leading cryonics researchers and writers.Dr. Emil Kendziorra and Aschwin De Wolf talk about the process in cryonics and cryopreservation of organs, especially brains. They also address doubts related to the damage that can be caused in the tissues of cryopreserved people, and overall dive into the state-of-the-art solutions and research in cryonics, foreshadowing what is going to be needed further and finally for successful revival. Music: I Knew a Guy by Kevin MacLeod is licensed under a Creative Commons Attribution 4.0 license. https://creativecommons.org/licenses/by/4.0/Session Summary: Emil Kendziorra & Aschwin De Wolf | Biostasis & Cryonics Q&A - Foresight Institute The Foresight Institute is a research organization and non-profit that supports the beneficial development of high-impact technologies. Since our founding in 1987 on a vision of guiding powerful technologies, we have continued to evolve into a many-armed organization that focuses on several fields of science and technology that are too ambitious for legacy institutions to support.Allison Duettmann is the president and CEO of Foresight Institute. She directs the Intelligent Cooperation, Molecular Machines, Biotech & Health Extension, Neurotech, and Space Programs, Fellowships, Prizes, and Tech Trees, and shares this work with the public. She founded Existentialhope.com, co-edited Superintelligence: Coordination & Strategy, co-authored Gaming the Future, and co-initiated The Longevity Prize. Apply to Foresight’s virtual salons and in person workshops here!We are entirely funded by your donations. If you enjoy what we do please consider donating through our donation page.Visit our website for more content, or join us here:TwitterFacebookLinkedInEvery word ever spoken on this podcast is now AI-searchable using Fathom.fm, a search engine for podcasts.  Hosted on Acast. See acast.com/privacy for more information.

“It looks like we could have an enormously bright future ahead of us, so we really need to worry about not going extinct now.”Anders is a research fellow at the Future of Humanity Institute, where he focuses on management of low-probability high-impact risks, estimating the capabilities of future technologies, and very long-range futures. Topics of particular interest include global catastrophic risk, cognitive biases, cognitive enhancement, collective intelligence, neuroethics, and public policy. Anders has a background in computer science, neuroscience and medical engineering. He obtained his Ph.D. in computational neuroscience from Stockholm University, Sweden, for work on neural network modeling of human memory.Anders dives into the far future, investigating how game theory might apply to galactic and universe scale civilizations.  Conquest, diplomacy, and economic forces will be subject to constraints of light speed travel and emergent properties of space expansion.  As our short term existential problems get solved, we may want to reflect on the future and figure out what long term goals we want and how to achieve themSession Summary: Anders Sandberg | Game Theory of Cooperating w. Extraterrestrial Intelligence & Future Civilizations - Foresight InstituteThe Foresight Institute is a research organization and non-profit that supports the beneficial development of high-impact technologies. Since our founding in 1987 on a vision of guiding powerful technologies, we have continued to evolve into a many-armed organization that focuses on several fields of science and technology that are too ambitious for legacy institutions to support.Allison Duettmann is the president and CEO of Foresight Institute. She directs the Intelligent Cooperation, Molecular Machines, Biotech & Health Extension, Neurotech, and Space Programs, Fellowships, Prizes, and Tech Trees, and shares this work with the public. She founded Existentialhope.com, co-edited Superintelligence: Coordination & Strategy, co-authored Gaming the Future, and co-initiated The Longevity Prize. Apply to Foresight’s virtual salons and in person workshops here!We are entirely funded by your donations. If you enjoy what we do please consider donating through our donation page.Visit our website for more content, or join us here:TwitterFacebookLinkedInEvery word ever spoken on this podcast is now AI-searchable using Fathom.fm, a search engine for podcasts.  Hosted on Acast. See acast.com/privacy for more information.

This episode is a Q&A on longevity investing with Sergey Young from Longevity Vision Fund and Neil Littman from Bioverge.Sergey Young is a longevity investor and visionary with a mission to extend the healthy lifespans of 1 billion people. He is the founder of the $100M Longevity Vision Fund—one of the few funds specializing exclusively in longevity and helping to accelerate longevity breakthroughs.Neil J. Littman is the Founder, CEO, and General Partner at Bioverge, an impact investment platform exclusively dedicated to investing in early-stage, cutting-edge healthcare companies.  Sergey speaks about his book, Growing Young, which covers different technologies and discoveries on the near horizon.  He believes that it is unlikely that a single intervention will create the change necessary, so he is building a portfolio of different technologies to target aging.  Neil Littman discusses his experience at the California Institute of Regenerative Medicine where he saw a girl cured of combined immunodeficiency disorder using gene therapy.   Session Summary: Sergey Young, Longevity Vision Fund | Neil Littman, Bioverge | Longevity Investing - Foresight InstituteThe Foresight Institute is a research organization and non-profit that supports the beneficial development of high-impact technologies. Since our founding in 1987 on a vision of guiding powerful technologies, we have continued to evolve into a many-armed organization that focuses on several fields of science and technology that are too ambitious for legacy institutions to support.Allison Duettmann is the president and CEO of Foresight Institute. She directs the Intelligent Cooperation, Molecular Machines, Biotech & Health Extension, Neurotech, and Space Programs, Fellowships, Prizes, and Tech Trees, and shares this work with the public. She founded Existentialhope.com, co-edited Superintelligence: Coordination & Strategy, co-authored Gaming the Future, and co-initiated The Longevity Prize. Apply to Foresight’s virtual salons and in person workshops here!We are entirely funded by your donations. If you enjoy what we do please consider donating through our donation page.Visit our website for more content, or join us here:TwitterFacebookLinkedInEvery word ever spoken on this podcast is now AI-searchable using Fathom.fm, a search engine for podcasts.  Hosted on Acast. See acast.com/privacy for more information.

What possibilities can there be for advanced civilizations within the realm of physics? What is the black hole solution? And what do astronomers spend a lot of time worrying about? In this Holiday Special episode of the podcast Creon Levit, Director of R&D at planet Labs, interviews physicist Adam Brown. Adam is a theoretical physicist at Stanford University, interested in early universe cosmology, inflation, black holes, and assorted other topics. Music: I Knew a Guy by Kevin MacLeod is licensed under a Creative Commons Attribution 4.0 license. https://creativecommons.org/licenses/by/4.0/Source: http://incompetech.com/music/royalty-free/index.html?isrc=USUAN1100199Artist: http://incompetech.com/Remarks: The length of this recording has been altered. Session Summary: Adam Brown, Stanford University | Q&A on Cosmology, Inflation and Black Holes - Foresight Institute The Foresight Institute is a research organization and non-profit that supports the beneficial development of high-impact technologies. Since our founding in 1987 on a vision of guiding powerful technologies, we have continued to evolve into a many-armed organization that focuses on several fields of science and technology that are too ambitious for legacy institutions to support.Allison Duettmann is the president and CEO of Foresight Institute. She directs the Intelligent Cooperation, Molecular Machines, Biotech & Health Extension, Neurotech, and Space Programs, Fellowships, Prizes, and Tech Trees, and shares this work with the public. She founded Existentialhope.com, co-edited Superintelligence: Coordination & Strategy, co-authored Gaming the Future, and co-initiated The Longevity Prize. Apply to Foresight’s virtual salons and in person workshops here!We are entirely funded by your donations. If you enjoy what we do please consider donating through our donation page.Visit our website for more content, or join us here:TwitterFacebookLinkedInEvery word ever spoken on this podcast is now AI-searchable using Fathom.fm, a search engine for podcasts.  Hosted on Acast. See acast.com/privacy for more information.

“In the mid 90s, we had a vision of smart contracting well before the invention of blockchain.”Mark S. Miller is a pioneer of Agoric (market-based secure distributed) computing and smart contracts, an architect of the Xanadu hypertext publishing system, a former Google research scientist, and a senior fellow of the Foresight Institute.Dean Tribble co-designed the negotiation process and contract for the first smart contracting system, AMiX. As a Principal Architect at Microsoft, he co-designed the Midori distributed object-capability operating system. This episode is a fireside chat Q&A with Mark S. Miller and Dean Tribble of Agoric. Agoric is an open-source development company launching an interoperable Proof-of-Stake chain and economy. Their JavaScript-native smart contract platform offers developers a safe, reusable library of DeFi components to rapidly build and deploy on-chain.Music: I Knew a Guy by Kevin MacLeod is licensed under a Creative Commons Attribution 4.0 license. https://creativecommons.org/licenses/by/4.0/ Session Summary: (390) Fireside Q&A with Mark Miller & Dean Tribble | The Agoric Approach to Computing - YouTubeThe Foresight Institute is a research organization and non-profit that supports the beneficial development of high-impact technologies. Since our founding in 1987 on a vision of guiding powerful technologies, we have continued to evolve into a many-armed organization that focuses on several fields of science and technology that are too ambitious for legacy institutions to support.Allison Duettmann is the president and CEO of Foresight Institute. She directs the Intelligent Cooperation, Molecular Machines, Biotech & Health Extension, Neurotech, and Space Programs, Fellowships, Prizes, and Tech Trees, and shares this work with the public. She founded Existentialhope.com, co-edited Superintelligence: Coordination & Strategy, co-authored Gaming the Future, and co-initiated The Longevity Prize. Apply to Foresight’s virtual salons and in person workshops here!We are entirely funded by your donations. If you enjoy what we do please consider donating through our donation page.Visit our website for more content, or join us here:TwitterFacebookLinkedInEvery word ever spoken on this podcast is now AI-searchable using Fathom.fm, a search engine for podcasts.  Hosted on Acast. See acast.com/privacy for more information.

“It’s not just about slowing aging down or stopping it, it’s about bringing yourself back to a younger biological age, which is effectively age reversal.”Daniel Ives, founder of Shift Bioscience, introduces their transcriptomic driver clock which enables them to identify putative drug targets for safer cellular rejuvenation, which might avoid the challenges coupled to therapeutic use of Yamanaka factors. Daniel goes into detail on what the clock enables, how they are planning to validate these putative targets, his wishlist for tools that could help speed up and de-risk longevity and aging focused drug development.Music: I Knew a Guy by Kevin MacLeod is licensed under a Creative Commons Attribution 4.0 license. https://creativecommons.org/licenses/by/4.0/Source: http://incompetech.com/music/royalty-free/index.html?isrc=USUAN1100199Artist: http://incompetech.com/Remarks: The length of this recording has been altered. Session Summary: Drug Target Discovery for Cellular Rejuvenation by ‘Driver’ Clocks | Daniel Ives, Shift Bioscience - Foresight InstituteThe Foresight Institute is a research organization and non-profit that supports the beneficial development of high-impact technologies. Since our founding in 1987 on a vision of guiding powerful technologies, we have continued to evolve into a many-armed organization that focuses on several fields of science and technology that are too ambitious for legacy institutions to support.Allison Duettmann is the president and CEO of Foresight Institute. She directs the Intelligent Cooperation, Molecular Machines, Biotech & Health Extension, Neurotech, and Space Programs, Fellowships, Prizes, and Tech Trees, and shares this work with the public. She founded Existentialhope.com, co-edited Superintelligence: Coordination & Strategy, co-authored Gaming the Future, and co-initiated The Longevity Prize. Apply to Foresight’s virtual salons and in person workshops here!We are entirely funded by your donations. If you enjoy what we do please consider donating through our donation page.Visit our website for more content, or join us here:TwitterFacebookLinkedInEvery word ever spoken on this podcast is now AI-searchable using Fathom.fm, a search engine for podcasts.  Hosted on Acast. See acast.com/privacy for more information.

Our civilization is made up of countless individuals and pieces of material technology, which come together to form institutions and interdependent systems of logistics, development and production. These institutions and systems then store the knowledge required for their own renewal and growth.Samo Burja is a sociologist and the founder of Bismarck Analysis, a firm that analyzes institutions, from governments to companies. His research work focuses on the causes of societal decay and flourishing. He writes on history, epistemology and strategy.History shows us we are not safe from institutional collapse. Advances in technology mitigate some aspects, but produce their own risks. Agile institutions that make use of both social and technical knowledge not only mitigate such risks, but promise unprecedented human flourishing.This episode of the podcast investigates this landscape, evaluates our odds, and tries to plot a better course.Music: I Knew a Guy by Kevin MacLeod is licensed under a Creative Commons Attribution 4.0 license. https://creativecommons.org/licenses/by/4.0/ Session Summary: New Strengthening Civilization video and "How-to": create positive futures - Foresight Institute The Foresight Institute is a research organization and non-profit that supports the beneficial development of high-impact technologies. Since our founding in 1987 on a vision of guiding powerful technologies, we have continued to evolve into a many-armed organization that focuses on several fields of science and technology that are too ambitious for legacy institutions to support.Allison Duettmann is the president and CEO of Foresight Institute. She directs the Intelligent Cooperation, Molecular Machines, Biotech & Health Extension, Neurotech, and Space Programs, Fellowships, Prizes, and Tech Trees, and shares this work with the public. She founded Existentialhope.com, co-edited Superintelligence: Coordination & Strategy, co-authored Gaming the Future, and co-initiated The Longevity Prize. Apply to Foresight’s virtual salons and in person workshops here!We are entirely funded by your donations. If you enjoy what we do please consider donating through our donation page.Visit our website for more content, or join us here:TwitterFacebookLinkedInEvery word ever spoken on this podcast is now AI-searchable using Fathom.fm, a search engine for podcasts.  Hosted on Acast. See acast.com/privacy for more information.

“We want to create a system where incentives for prediction are transparent and clear to make good predictions. Furthermore, we want these predictions to be integrated into a consensus that we could all use and rely on if we weren't specialists in the topic.” - Robin HansonToday we will discuss prediction markets and the problems they may help solve. We’ll hear a brief introduction of what Prediction Markets are by Robin Hanson, followed by a discussion of a few current projects (Metaculus, Augur, Replication Markets), and finish with a rundown of the challenges ahead by Chris Hibbert of Agoric and Martin Koeppelmann of Gnosis.This episode of the podcast is a special one, it features several guests speaking on the topic of prediction markets. They cover concepts, early prototypes, current (decentralized) applications, potential problems and future opportunities.Speakers: Robin Hanson - George Mason UniversityAnthony Aguirre - MetaculusPaul Gebheim - AugurThomas Pfeiffer - Replication MarketsMartin Koeppelmann - GnosisChris Hibbert - Agoric Session Summary: Prediction & Replication Markets, Augur, Metaculus, Gnosis, Oracle Problems, Beauty Contests - Foresight InstituteThe Foresight Institute is a research organization and non-profit that supports the beneficial development of high-impact technologies. Since our founding in 1987 on a vision of guiding powerful technologies, we have continued to evolve into a many-armed organization that focuses on several fields of science and technology that are too ambitious for legacy institutions to support.Allison Duettmann is the president and CEO of Foresight Institute. She directs the Intelligent Cooperation, Molecular Machines, Biotech & Health Extension, Neurotech, and Space Programs, Fellowships, Prizes, and Tech Trees, and shares this work with the public. She founded Existentialhope.com, co-edited Superintelligence: Coordination & Strategy, co-authored Gaming the Future, and co-initiated The Longevity Prize. Apply to Foresight’s virtual salons and in person workshops here!We are entirely funded by your donations. If you enjoy what we do please consider donating through our donation page.Visit our website for more content, or join us here:TwitterFacebookLinkedInEvery word ever spoken on this podcast is now AI-searchable using Fathom.fm, a search engine for podcasts.  Hosted on Acast. See acast.com/privacy for more information.