David Mischoulon, a prominent psychiatrist at Massachusetts General Hospital and Harvard Medical School, delves into the intriguing world of Cannabidiol (CBD) and its psychiatric applications. He discusses its potential benefits for disorders like social anxiety and schizophrenia, highlighting the importance of scientific evidence over hype. Mischoulon emphasizes cautious usage, the mechanisms behind CBD, and real-world case studies demonstrating its therapeutic effects. Is CBD the future of mental health treatment or just a trend?

Join Gregory Pontone, an expert in psychopharmacology, as he discusses groundbreaking insights on using medical cannabis to treat Parkinson's disease. He reveals a study showing that 87% of patients experienced symptom improvements, challenging conventional treatments. Pontone dives into practical dosages, potential risks, and personalizing care for optimal results. Could this be the versatile answer for managing both motor and non-motor symptoms? Tune in for fascinating revelations about the future of Parkinson's care!

David Mischoulon, Director of the Depression Clinical and Research Program at Massachusetts General Hospital, discusses the promise of N-acetylcysteine (NAC) in treating mood disorders. He explores how NAC protects brain cells and its potential advantages over traditional medications, particularly regarding side effects. The conversation dives into compelling clinical trial evidence linking NAC to improved outcomes in depression and bipolar disorder, highlighting its appeal as a non-pharmaceutical alternative for both adults and children.

David Rosenberg, an expert in child and adolescent psychiatry, dives into the intriguing link between gut health and ADHD. He discusses a recent meta-analysis examining the potential role of probiotics in managing ADHD symptoms. While results show limited efficacy when used alone, there are hints of benefits when combined with traditional treatments. This fascinating conversation pushes the boundaries of ADHD research and highlights the need for further exploration into alternative therapies.

Vivien Burt, M.D., a specialist in bipolar disorder, discusses the complexities of managing this condition during pregnancy. She emphasizes the critical balance between maternal mental health and fetal safety. The conversation covers the risks and benefits of medications like lithium and lamotrigine. Individualized treatment plans are highlighted as essential for effective care. The episode also explores recent research and guidelines for navigating these unique challenges, ensuring the well-being of both mother and child.

Scott Beach, an expert in psychopharmacology, sheds light on a recent study examining haloperidol's safety for older patients experiencing post-surgery delirium. The discussion challenges existing safety concerns and considers haloperidol as a viable option compared to atypical antipsychotics. Beach emphasizes the importance of personalized medication strategies and careful prescribing to ensure patient comfort. Could haloperidol be the overlooked solution in managing geriatric delirium? Tune in to discover this thought-provoking perspective.

Vivien Burt, Professor Emeritus of Psychiatry at UCLA, discusses the intricate decision-making process surrounding atypical antipsychotics use during pregnancy, particularly for women with bipolar disorder. She highlights recent research showing no significant risk of major birth defects, emphasizing the need to balance maternal mental health with fetal safety. The conversation stresses the importance of effective communication between healthcare providers and patients to navigate treatment benefits and potential risks for newborns.

David Rosenberg, a leading expert in child and adolescent psychiatry, discusses his groundbreaking observational study on using risperidone to treat anorexia nervosa in young patients. He highlights the urgent need for effective medications in this challenging area. Despite risperidone being well tolerated, the study reveals it did not significantly improve outcomes like weight gain. Rosenberg emphasizes the complexity of treating this disorder and the necessity for further research into long-term effects and alternative solutions.

Vivien Burt, Professor Emeritus of Psychiatry at UCLA and a leading expert on lithium management in pregnancy, discusses critical strategies for treating expectant mothers with bipolar disorder. She explains how lithium levels fluctuate during pregnancy and the importance of careful monitoring. The conversation includes practical dosing recommendations and considerations for postpartum care, ensuring both mother and baby remain healthy throughout this journey. A real case study illustrates the challenges and solutions in managing these complex cases.

Carlos H. Schenck, a prominent sleep medicine specialist at the University of Minnesota, shares groundbreaking insights on daridorexant, a novel treatment for chronic insomnia. He discusses how this dual orexin receptor antagonist uniquely targets wakefulness, potentially transforming insomnia care. The conversation delves into its impressive efficacy—reporting 78% of patients experienced significant symptom relief—and examines the implications for future treatments, including its potential applications for narcolepsy and sleep apnea.