Thyroid Mystery Solved: Hashimoto's and Hypothyroidism Revealed

The Case:  Helen has 2 different autoimmune diseases and hypothyroidism and rarely feels good. She was experiencing fatigue, brain fog, body aches, and depression. She wasn’t sure if the depression was a symptom or something caused by her struggles.The Investigation When I met Helen, I saw that there were many areas where we could start to intervene. I knew we had to look at her DNA blueprint if we were going to solve this health mystery. There are a lot of different ways that our DNA can inform us about our health but Kashif Khan has a unique approach. I knew he’d be the right person to talk to about Helen’s case. Thought Leader in Functional Genetics Kashif  Khan is the author of The DNA Way, a two-time TEDx Speaker and the Founder of The DNA Company, where personalized medicine is being pioneered through unique insights into the human genome. He is also the host of the Unpilled podcast. He knows firsthand the power of understanding your DNA blueprint because he was able to heal his own issues through functional genetics. Understanding the Story Our Genes Are Really Telling Us So many people plagued with health issues blame their genes. What most don’t realize is that our genetic makeup does not completely determine our health. Genes can turn on and off, we can provide detours that will get us to better health outcomes. In my conversation with Kashif, he explains that often, people look at DNA testing as a way to determine the likelihood that they will experience disease. For example, one DNA test might tell you that you have an 80% chance of breast cancer. Kashif feels like the model of DNA testing is broken because the body doesn’t work that way. He suggests a more comprehensive approach that requires us to understand the genome properly. We can move from ‘this gene equals this problem’ to ‘this gene informs us how your body functions and the most supportive nutrition and lifestyle choices.’ It’s a much more functional approach to genetics and addresses disease, chronic conditions, and overall health which I really appreciate because it’s so empowering. Functional Genetics and Autoimmunity (Hashimoto’s) Helen has 2 autoimmune diseases and has hypothyroidism so I was curious to hear what Kashif had to say about the role that gene expression plays in autoimmune disease. He explained there is a race to identify the autoimmune gene, but the body doesn't work in such a straightforward manner. It's becoming evident, he says, that the underlying system's failure (rather than a single gene) is what leads to autoimmune conditions. He shares a powerful example relating to hormone toxicity in women. There is a hormone cascade that involves the production, conversion, and clearance of hormones. If a woman is estrogen dominant and lacks proper detox pathways, exposure to hormone disruptors in the environment or additional estrogen from birth control or hormone therapy can lead to chronic inflammation and eventually manifest as an autoimmune condition or other health issues. The outcome varies among individuals based on their specific hardware failures. This example highlights that, while there may not be a direct gene that causes autoimmunity, understanding the pathways and habits can empower individuals to make informed choices and take preventive measures from a young age.In other words, gene expression plays a role in autoimmunity but is not 100% of the picture. Can Your DNA Impact Gut Health? When examining our DNA and its relationship with the gut, there are important insights to consider, says Kashif. One significant finding is the impact of specific dietary choices. For example, the growing popularity of veganism has led many individuals to adopt this lifestyle. However, it is crucial to recognize that not everyone possesses the genetic makeup necessary to break down certain plant-based proteins found in beans, lentils, legumes, and chickpeas. Over time, those lacking the required enzyme may experience symptoms resembling an autoimmune condition due to the strain placed on their gut by consuming these protein sources as their primary protein intake. This example illustrates the importance of aligning dietary choices with individual genetic predispositions. The same caution goes out to those following a Keto or carnivore diet - they may initially feel great but after a few weeks, they discover health issues simply because they are not genetically aligned with their diet. This is why it’s so powerful to get a map of your genetic makeup because even “healthy eaters” may discover that their misaligned diet plan is the root cause of their health concerns. Can Our Genes Cause Brain Fog? Our genetics play a significant role in our brain health and overall cognitive function. Kashif says individuals may experience symptoms in varying ways due to their unique genetic makeup. For example, some individuals may be more prone to brain fog or joint pain, while others may have different manifestations. Mitochondrial health is crucial for brain function, as the brain has the second highest density of mitochondria in the body. Some people may have genetic factors that affect mitochondrial function, making them more susceptible to brain-related symptoms and difficulties. Another genetic factor is a gene called BDNF, which influences neuroplasticity, brain repair, and neurogenesis. Individuals who struggle with efficient neuroplasticity and brain repair may experience greater challenges in handling cognitive loads, with symptoms such as brain fog setting in more quickly and taking longer to recover from. Perception is also influenced by genetics, explains Kashif. Individuals may have different neurochemical maps that affect risk aversion, reward-seeking behavior, procrastination, or susceptibility to burnout. On the other hand, some individuals may have fewer dopamine receptors, leading to increased seeking behavior, while others may experience difficulties in experiencing dopamine at appropriate levels. Is Autism Genetic? Considering the role of gene expression in the brain, it made me curious about autism. In the functional medicine world, there are so many thoughts about contributing factors. From exposure to heavy metals to gut microbes, to obesity, autoimmunity and the gut-brain connection. Kashif has worked with autistic children and says it’s important, when talking about the cause and support of autism, to distinguish between innate autism (a child is born with the condition), and acquired autism (external factors contribute to its development). He says the allopathic medical perspective tends to view all autism as innate, while the functional medicine approach attributes it to outside exposure. Both perspectives have validity, but they do not account for the entire spectrum of autism. He further explains that the first step is to determine which category the child falls into. If it is innate, the focus is on improving brain function and addressing behavioral development issues, as it is not reversible. Functional interventions can still help the child thrive, but the underlying condition remains. Research is ongoing to identify the switch that triggers autism, but it is yet to be discovered. However, a significant portion of autism cases fall into the second category, where a child was initially fine but experienced a change after a specific event. In these cases, inflammation caused by that event or events can lead to brain inflammation and altered development. Understanding the child's unique genetic makeup is essential to determine the appropriate approach. By focusing on the "why" rather than just the condition itself, individualized...

The Investigation Back in my 20s, I started to notice that sometimes my brain was just not clear. It might be me forgetting a friend's name or missing an appointment. It happened so often that I started to normalize it. I would shrug it off even when friends pointed it out with concern. When I did bring the issue to my conventional doctor, it was dismissed.  But, even back then, I knew there was something else going on. I knew that I had to get to the bottom of this health mystery around my brain fog.  Decades later, I know a lot more about brain fog and in this episode, I want to share 4 of the most common causes of brain fog and what you can do about it.  Reason #1: Hypothyroidism Brain fog is closely linked to hypothyroidism, a condition where the thyroid gland doesn't produce enough hormones. This deficiency affects the membranes that support brain function, leading to cognitive difficulties. To overcome brain fog caused by hypothyroidism, it's essential to prioritize thyroid support tailored to your specific needs and, most importantly your thyroid type. If you don’t know your thyroid type, it’s really essential for supporting your thyroid just for you. I will be showing you how to figure this out on June 15th so that instead of feeling stuck, confused and frustrated, you will have clarity and certainty which means you will know exactly what to do to support your thyroid. And ultimately what this really means is that you can finally have peace of mind that you are not alone in your struggles because you will have support from someone who really gets it. Click here to register. Reason #2: Hashimoto’s Disease Another primary contributor to brain fog is Hashimoto’s disease because of all of the inflammation that comes along with Hashimoto’s. What happens with Hashimoto’s is that the immune system gets confused and starts to believe the thyroid is a threat. It attacks it but that’s not just bad for the thyroid, it has repercussions throughout the body because the immune system is stuck in attack mode. The brain is one of the areas under attack and as a result, inflammation occurs causing brain fog.  To combat brain fog associated with Hashimotos, it's crucial to identify and address triggers that contribute to inflammation. Our upcoming training is also helpful for those dealing with Hashimoto’s as it includes in-depth knowledge and effective strategies to help you on your healing journey, empowering you to reclaim mental clarity. Reason #3: Shifts in Estrogen and Hormonal Balance Fluctuations in estrogen levels during puberty, pregnancy, postpartum, and menopause can wreak havoc on our cognitive abilities, making it another potential cause of brain fog. This foggy state is particularly evident when estrogen levels drop, resulting in symptoms like "Mommy-brain" after childbirth or during menopause. If you have both Hashimoto’s and hypothyroidism, it's paramount to prioritize support for your thyroid as it directly impacts hormone balance.  Maintaining hormonal balance is crucial for optimal brain function. Strategies such as stress management, regular exercise, and targeted supplements can support hormone balance and alleviate brain fog related to hormonal fluctuations. You can also explore natural support options like Fem Guard or consider hormone support, as discussed in episode 96 and also episode 110 of Health Mysteries Solved, where we demystify hormones for perimenopause and menopause. Reason #4: Inflammation and Free Radicals The fourth major cause of brain fog is the presence of free radicals in the body. Free radicals damage our cells and when the body is inflamed, free radicals are created. Even if the inflammation doesn’t start in the brain, it can travel and spread into the brain and cause brain fog. This is a significant concern for those with Hashimoto’s or other autoimmunity issues but even for people who don't have autoimmunity, the initial inflammation could be caused by exposure to certain toxins, foods, oxidative stress, or other triggers. It's crucial to adopt measures that reduce overall inflammation through lifestyle modifications and dietary choices. By doing so, you can minimize the negative effects on your cognitive abilities and experience improved mental clarity. Supplements for Brain Fog that Really Work With decades of experience and exploration in reducing inflammation and the brain fog that comes with it, I’ve discovered a handful of supplements that I like to recommend. As always, please consult your own personal health practitioner before starting a new supplement regimen. Here are the ones I find to be effective:  Annatto E 300 by Designs for Health Annatto-E 300 is a remarkable brain fog supplement. It contains unique forms of vitamin E that are 50 times stronger than conventional supplements. This potent formulation specifically targets lipid oxidation, which plays a crucial role in maintaining optimal brain function. By incorporating Annatto E 300 into your daily regimen, you can support your brain health and combat brain fog effectively. We offer 10% off any Design for Health products on our website just enter the promo code: DFH10. Biotoxin Binder Biotoxin Binder is a powerful supplement that combines humic and fulvic acid, known for its ability to bind toxins, chemicals, allergens, and molds. What sets this supplement apart is its compatibility with other supplements and the fact that it can be taken with food. The convenience and efficacy of Biotoxin Binder make it an excellent choice for supporting your brain health and combating brain fog. NeuroFlam NeuroFlam is a meticulously crafted brain fog supplement that provides a range of potent antioxidants to support optimal brain function. By combating oxidative stress and inflammation, NeuroFlam helps promote cognitive clarity and combat brain fog effectively. Including NeuroFlam in your daily routine can be a valuable step towards regaining mental clarity and banishing brain fog. Please note that you will need to create a free account to purchase this product. (it only takes 3 seconds) Take Action Against Brain Fog If you find yourself grappling with brain fog, remember that you are not alone, and there are tangible steps you can take to address it. Understand...

The Case:  Laura has thyroid issues causing her to feel overweight and her constantly dry skin made her feel like she was aging too fast.  She suspected that her issues might be genetic so she did a DNA test which revealed that she had the MTHFR gene. She tried biohacking; taking high doses of B vitamins and a cocktail of other supplements but nothing got her the results she was looking for. Investigation My suspicions were that her various supplements might not be right for her. I also wanted to take a closer look at her diet and lifestyle. Because I suspected that the answers were going to be found at the intersection of genetics, diet, and lifestyle I knew that Dr. Kara Fitzgerald would be the perfect person to consult with since she is an expert in epigenetics, nutrition, and aging. She is the author of two incredible books, Younger You: Reduce Your Bio Age and Live Longer, Better and  Better Broths & Healing Tonics: 75 Bone Broth and Vegetarian Broth-Based Recipes for Everyone. Unveiling the Power of Epigenetics We often associate our health, thyroid function, and immune system with genetics and autoimmunity. However, as Dr. Kara explains, it is not our genes alone that determine our level of health, immune system function, or even our age. Instead, it is our epigenetics that play a significant role. I know there's a lot of confusion surrounding this topic, and in this episode, Dr. Kara shed some light on it.She explains that in the early 2000s, scientists successfully deciphered the human genome. They discovered that we possess a little over 23,000 genes, and many believed that this knowledge would provide a clear roadmap to understanding and treating diseases. However, the reality turned out to be quite different. In over 90% of cases, genes alone do not determine our health outcomes. For most of us, the key lies in how our genes are being turned on and off—a fascinating field known as epigenetics that we’ve covered before in episode 143. Unleashing the Potential of Epigenetic Expression Epigenetics emerged as a prominent field of study after the completion of the Human Genome Project. It explores the factors that influence gene expression, such as our diet, exposure to toxins, stress levels, social connections, and exercise habits. Simply put, we have the power to determine which genes are activated and which ones remain dormant. Ideally, we want to activate the genes associated with health, longevity, and overall well-being while silencing those that contribute to disease progression.This realization is particularly empowering for individuals like Laura, who believed that her family history of Hashimoto's meant she was destined to follow the same path. However, epigenetics shows us that we are not bound by our genetic heritage alone. Lifestyle and Nutrition: The Epigenetic Keys Dr. Kara dives into the exciting realm of lifestyle and nutrition, revealing some of the most significant factors that influence gene expression. Understanding these keys can help us unlock the potential for anti-aging, detoxification, and disease prevention.1. Diet Program: Dr. Kara shares insights from a groundbreaking study on biological aging, which focused on DNA methylation—a marker of aging and gene expression changes. The study participants followed a specific diet program designed to optimize gene expression. The key elements of this diet program include:Veggies and Greens: Emphasizing a plant-rich diet with an abundance of greens and cruciferous vegetables, cooked to support thyroid health.Low-Glycemic and Fruit-Dense: Opting for low-glycemic vegetables and incorporating dark berries rich in polyphenols.Smart Protein Choices: Eggs and liver (if open to consuming them) are excellent gene whispering foods, while seeds, nuts, and fatty fish provide essential nutrients.Healthy Oils: Including extra virgin olive oil and coconut oil in cooking.Vitamin D and Mushrooms: Ensuring sufficient vitamin D intake and recognizing the gene-regulating properties of mushrooms, such as shiitake and maitake. 2. Herbs and Spices: Dr. Kara highlights the impact of polyphenols found in various herbs and spices. Rosemary, thyme, oregano, curcumin, turmeric, quercetin, and resveratrol are just a few examples of potent gene regulators.It's important to note that while we may inherit some gene expression patterns from our parents and ancestors, we still hold the reins and have the power to influence our health destiny. Understanding this gives us the opportunity to make informed choices and take control of our well-being.Dr. Kara emphasizes the vital connection between epigenetics, aging, and thyroid disease. Aging acts as a primary driver for various chronic conditions, including hypothyroidism, Graves' disease, and subclinical hypothyroidism. Exploring the changes in epigenetic expression and DNA methylation provides valuable insights into the underlying mechanisms of these conditions. Epigenetic Lifestyle: A Holistic Approach to Optimal Health Dr. Kara uses her study and others as examples to showcase that it's not just about individual foods but a synergistic combination that maximizes the effects on gene expression. She explains that her program incorporates low glycemic choices, intermittent fasting, exercise, and other crucial lifestyle factors. The Power of Simple Lifestyle Changes Dr. Kara says the key to success is by making simple, doable lifestyle changes to improve our health and slow down the aging process. She emphasizes that the goal is not to engage in extreme measures but rather to focus on sustainable habits that can positively impact our overall well-being. That was the motivation behind her research team’s design of a program called "Younger You" that aimed to create meaningful changes in participants' health. The program included a simple exercise prescription, prioritized quality sleep, incorporated basic meditation practices, and recommended the use of a greens powder and probiotic supplement.The results she shared were truly astonishing to me. Understanding the Role of DNA Methylation DNA methylation plays a crucial role in gene expression and epigenetics. We’ve talked about this before (on this episode about the MTHFR gene) but it’s important to go beyond that. Methylation is involved in numerous essential processes in the body, from metabolizing hormones and neurotransmitters to maintaining optimal cell function. Methylation is influenced by various factors, including nutrients, gut health, and the microbiome.Comprehensive testing is needed to assess methylation status and overall metabolic function. This involves looking at biomarkers such as homocysteine and methylation cycle intermediates. A functional medicine approach goes beyond the methylation cycle and explores other metabolic aspects, including gut health and individual nutrient needs. By understanding each person's unique metabolic profile, personalized interventions can be implemented to o...

The Case:  Mindy has Hashimoto’s and hypothyroidism and experiences low energy and anxietyShe’s worried genetics may be making it worse because her mother also has Hashimoto’sShe’s feeling like the genetic cards are stacked against her and there’s nothing she can do to feel healthy again.  The Investigation When I first met Mindy, I noted the stock she was placing on her genetics, missing things under her control. Genetics are important but they only account for 15% of our wellness picture. I knew that there were a myriad of things we could do to shift the impact of her genetics on her health. However, I also knew that a bigger shift might be needed at the epigenetic level.  The Epigenetic Expert - Anat Peri To look further into what might be going on for Mindy, I invited Anat Peri back to the show. Longtime listeners may remember her from episode 55 of Health Mysteries Solved when she shared her insights on emotional resilience. I highly recommend going back and listening to (or relistening to) that episode. Anat is an inner child expert and the founder of Training Camp for the Soul. She has 18 years of experience as a trauma-informed coach using a variety of tools including mindset, somatic healing, safety connection, nervous system regulation, and inner child reparenting. Through her work, she has learned a great deal about epigenetics and how our upbringing can manifest physically in our adult minds and our health.  What is Epigenetics? Epigenetics refers to the biology of our beliefs and how we view the world. It's about how our reactions to life impact our nervous system and whether we operate in a parasympathetic state or a stressful (sympathetic) state. This can have a huge impact on our health, as stress and trauma can lead to a range of health issues and can be a major trigger for Hashimoto’s. Anat explains that everything we learn as children is learned from our caretakers, and if they were absent or dysfunctional, we may have learned unhealthy patterns that can impact our health as adults. Anat explains that we learn so much at a young age because as children we are like sponges; soaking up what we see, hear, and feel energetically from our caretakers. Our beliefs and the way we view the world are formed at a young age, and they can have a huge impact on our health later on. Often, we are completely unaware of the role epigenetics is playing in our health.The good news is that we can turn our epigenetics on and off, just like gene expressions. Our ability to control our epigenetics depends on our beliefs, how we regulate our nervous system, and how we speak to ourselves. Inflammation and its Impact on Health Inflammation is a natural response of the immune system to injury or infection. However, chronic inflammation can contribute to a wide range of health issues, including autoimmune diseases such as Hashimoto's and thyroid issues. In my practice, I’ve seen how specific beliefs and behaviors can contribute to inflammation in the body. Beliefs and Behaviors that Impact Inflammation and Hashimoto’s One of the beliefs that can increase inflammation is shame. Anat explains that shame is a powerful enough emotion that it can cause us to close in on ourselves and hide our true selves. When we feel ashamed, we may try to suppress our emotions and our needs, which can lead to chronic stress and inflammation.Fear is another powerful emotion that can contribute to inflammation, says Anat. When we are in a state of fear, our bodies release stress hormones, such as cortisol and adrenaline. Over time, chronic stress can lead to inflammation in the body.Our parents may have ingrained shame and fear responses into us at a very young age without realizing it. Growing up in a chaotic or turbulent environment can also contribute to inflammation. When our nervous system is constantly activated by stress and fear, our bodies release stress hormones, which can lead to inflammation over time. The Potential Role of Fathers in the Development of Autoimmune Diseases In this episode, we really got personal. I looked at the roles my mother and father played in my life. I shared that I felt like my father was always there for me but he didn't necessarily stand up for me when my mother wanted me to do things I didn't want to do, like playing the piano. This experience taught me that my feelings didn't matter and that I had to do what others wanted me to do. I realize now that this is how I was trained to be a people pleaser. Anat was able to relate that to having a lack of boundaries as well as self-rejection and self-abandonment and the connection to my Hashimoto’s. It’s really fascinating.Anat expanded the discussion further by explaining how fathers can impact the development of autoimmune diseases. She notes that fathers can influence the development of autoimmune diseases by being emotionally unavailable, neglectful, or critical. Children who grow up with fathers who are emotionally unavailable may feel rejected and develop feelings of low self-worth, which can trigger the onset of autoimmune diseases.We also talk about how fathers can influence the development of autoimmune diseases by modeling certain behaviors. For example, if a father is always putting others' needs before his own, his children may learn that it's not okay to prioritize their own needs.This is why it’s so important to have a healthy relationship with both parents to reduce the risk of developing autoimmune diseases. It's crucial for fathers to be emotionally available and supportive of their children's feelings and needs. It’s also important for fathers to model healthy behaviors, such as setting boundaries and prioritizing self-care, to help their children develop a healthy attitude towards themselves and others. Techniques to Connect with Your Inner Child and Begin the Healing Process Regardless of our relationship with our fathers and how it may have impacted our health, it is possible to change it now. Anat says this is possible by connecting with our inner child. This allows us to identify our emotions, feelings, beliefs, and desires as they relate to our health issues. She suggests grabbing a journal or a piece of paper and writing down everything we feel triggered, upset, frustrated, or stuck about. Alternatively, we can record ourselves talking as if we are calling our best friend who listens to us without judging. Once we have our thoughts and emotions recorded, we can identify our inner child's voice by looking for statements that begin with "I feel" or "I want." This practice helps us weed out our inner critic, ego, and shadow, which can hinder our ability to connect with our true feelings and desires.Anat says it’s important to make sure that we are truly hearing our inner child’s voice because it’s generally not the loudest. Often, our inner critic, ego, and shadow are much more overbearing. She explains that statements that begin with "I am," "I'm upset," "I'm angry," "I feel like he doesn't listen to me," "I feel like I'm being left behind," or "I'm all alone" represent our inner child's voice. On the other hand, statements that contain "I should," "I must," or "I have to" reflect our inner critic. Meanwhile, statements that blame others and avoid taking responsibility for our feelings are the product of our ego. Finally, statements that contain shame, fear, and guilt reflect our shadow.By identifying our inner child's voice and distinguishing it from our inner critic, ego, and shadow, we can begin the healing process. Connecting with our emotions and desires is crucial to understanding ourselves and our experiences fully. It also helps us identify limiting beliefs th...

The Investigation Those of you who have been listening to the show for a while might remember the challenges I had with coloring my hair during the pandemic. This upset to my regular routine led me to seek out a healthy, at home option. I was particularly curious about how dying my hair may have impacted the management of my Hashimoto’s. You can hear more about that in Episode 121.  Well, it’s been a year since then and I wanted to give you an update. In this episode, I deep dive into the problem with hair dye for people with autoimmunity, Hashimoto’s and thyroid issues. Plus, I share my review of Hairprint after one year of continuous use.    The Problem with Traditional Hair Dyes for Autoimmunity and Hypothyroidism Chemicals in hair dye act as immune triggers. This can be a big issue for anyone with an autoimmune disease like Hashimoto’s because the immune system is already confused and attacking the thyroid. More confusion means more attacks which can result in a flare up or subtle symptom shifts. If you have hypothyroidism, you may already be dealing with: Hair loss Thinning hair Dry brittle hair Frizzy hair Unfortunately, using traditional hair dye can make it worse.  Traditional hair dyes use harsh chemicals like ammonia or nanolumens to break apart the layers of the hair protein to give the dye access to the hair shaft. Even ammonia-free dyes use chemicals like Paraphenylenediamine (PPD) that are potentially harmful (they’re even banned in Canada and the EU). Moreover, chemicals in hair dyes seep into the bloodstream during the dying process, causing harm to the immune system, respiratory system, liver, kidneys, and can trigger serious allergic reactions, hair loss, and hair breakage.   Why You May Want to Avoid the ‘Organic Hair Dyes’ The term ‘organic’ is not defined, recognized, or regulated by the FDA in the personal care industry. Companies can add natural ingredients and call their hair dyes organic or natural, but it doesn't mean that they're chemical-free.  Often, the added botanical or organic elements have nothing to do with the dyeing process and are there in addition to all the usual chemicals that are in conventional hair dye. It might just be a marketing gimmick.   Hairprint: A Safer Alternative to Traditional Hair Dye? I was thrilled to find Hairprint last year for all of the reasons I listed above. Before I share more about the product, I want to clarify that this is not a sponsored post - I genuinely use the product and love the product. And, in the past year of using it, I’ve learned a lot about how to get the best results.  First, let me share a bit about Hairprint (in case you missed episode 121). It’s a unique product that doesn't break up the hair follicle and degrade it in any way, unlike traditional hair dyes. This makes it a safer alternative for everyone but especially for those with thyroid issues or autoimmune diseases. It actually restores the natural pigment in hair without using harsh chemicals.  How to Apply Hairprint (and Get the Most Out of It) If you've been using Hairprint or plan to use it, it's important to note that it can have a slight drying effect on your hair, even though protein is great for hair. To combat this, I highly recommend hair oiling. You can use moisturizing oils such as amla oil, argan oil, or jojoba oil. You can apply the oil to the full length of your hair or just the ends depending on where you need it and if you want to avoid adding oil to an oily scalp. Now, if you have a dry scalp, you can apply it there as well. Apply the oil 15-20 minutes before shampooing, or even better, leave it in overnight and wash your hair in the morning.  I have noticed a significant improvement in my hair's manageability and moisture since starting this practice. I apply the oils right after I do my Hairprint application and then once a week, or sometimes twice a week if I have time. This has made such a difference for my hair, and I highly recommend it for anyone with dry hair, whether or not you are using Hairprint.   Guilt Free Hair Coloring One of the great things about using Hairprint is that it's natural, so you don't have to feel guilty about coloring your hair more often. You can do it at home without spending a lot of money or spending time traveling to a salon. It's empowering to be your own self-advocate and take control of your hair health.    My Final Take on Hairprint By now, you can tell that I love it. If you have been hesitant to try Hairprint, I encourage you to give it a try and take care of your hair naturally.   Eliminating Health Mysteries If changing how you color your hair can reduce your exposure to toxins, it might just be what you need to shift the scales and help you solve your own health mystery. If you think this episode could be helpful to someone you love, please share it.    Links: https://www.myhairprint.com/ Related Podcast Episodes: 10 Reasons Your Hair is Falling Out w/ Deb Matthew 139 How to Power Up Your Hashimoto’s and Thyroid Healing Journey with Hypnosis Part 1 [Ask Inna] Answers to All Your Hashimoto’s Questions [Ask Inna] More Answers to Your Hashimoto’s Questions (Part 2) Thanks for Listening If you like what you heard, please rate and review this podcast. Every piece of feedback not only helps me create better shows, it helps more people find this important information. Never miss an episode -  Subscribe NOW to Health Mysteries Solved with host, Inna Topiler on Apple Podcasts, Spotify, Stitcher or Google Podcasts and remember to rate and review the show! Find out more at http://healthmysteriessolved.com   PLEASE NOTE All information, content, and material on this podcast is for informational purposes only and is not intended to serve as a substitute for the consultation, diagnosis, and/or medical treatment of a qualified physician or healthcare provider. Some of the links provided are affiliate links. This means we may make a very small amount of money should you choose to buy after clicking on them. This will in no way affect the price of the product but it helps us a tiny bit in covering our expenses.  

The Case:  Hadley has been struggling with weight loss for years and is now in perimenopause.She’s tried many diets but the results were temporary.She eats mindfully avoiding gluten, processed foods, and sugar.She was intrigued by the hype around Ozempic (semaglutide) but wanted to make sure it was safe and that there weren’t other issues at play in her weight mystery. Weight Loss Struggles and Hormone Changes in Perimenopause Hadley’s struggle is so common. Perhaps it’s familiar to you too? You hear about the latest trend in weight loss and wonder (hope) that it’s going to be what helps you get your metabolism working in your favor so you can drop those last few pounds and keep them off. Ozempic has put semaglutide in the news with so many people talking about its popular side effect of weight loss with ease. But, like Hadley, you may have wondered - is it safe and does semaglutide really work for weight loss? The Functional Medicine View of Ozempic for Weight Loss Emily Sadri is a long-time friend of the show. She joined us on  episode 107 to share all kinds of eye-opening information about birth control pills and thyroid. Because of that informative episode, I knew she was just the person to talk to about Hadley’s case and this trend of using semaglutide for weight loss purposes.Emily is a board-certified Women's Health Nurse Practitioner, and hormone and weight loss expert. She owns and operates a boutique women’s functional medicine practice in Cleveland, Ohio, and helps women everywhere live more balanced, healthier lives. What is Semaglutide (originally marketed as Ozempic)? Semaglutide is a peptide drug that was initially marketed as a medication for diabetes. Developed by Novo Nordisk in 2012, semaglutide was later found to have the potential for weight loss. The drug is now available under the commercial name Wegovy and is prescribed for obesity. How does Semaglutide Work? One of the most impressive things about semaglutide is its multi-faceted approach to weight loss. Unlike many weight loss medications that rely on appetite suppression or stimulants, semaglutide works by slowing down digestion and promoting a feeling of fullness.In this episode, Emily explains that by slowing gastric emptying, semaglutide delays the movement of food from the stomach into the small intestines, which helps to control appetite and reduce food intake. The drug also acts on the hypothalamus, a part of the brain that regulates signaling for many different functions.The hypothalamus controls sympathetic nervous system signaling, and semaglutide modulates and increases sympathetic output just enough to stimulate lipolysis or fat breakdown. This action raises people's basal metabolic rate slightly, which over time results in weight loss. What did the Clinical Studies on Semaglutide Find? Clinical studies have shown that people treated with semaglutide for weight loss have an average of 15% body weight loss, which is a remarkable achievement. This weight loss was achieved without significant lifestyle or diet counseling, making semaglutide seem like exactly what the weight loss market has been waiting for. But…As a practitioner who primarily works with women aged 35 to 55 who often have a thyroid issue or Hashimoto’s, I'm sensitive to anything that stimulates stress pathways. Emily agrees with my caution but says semaglutide is an appealing option for women who are looking to lose weight but want to avoid the side effects of stimulant-based medications. Unlike stimulants, semaglutide doesn't suppress appetite in the same way, which is better for metabolism in the long term. However, sustainable weight loss isn’t just about eating less. Exploring the Emotional Component of Weight Loss In this episode, we also discussed the emotional component of weight loss and how important it is to acknowledge and address it. We talked about how people need reassurance to feel confident about the weight loss process and how feedback can be a useful tool in achieving success.She explained that extreme dieting can be deleterious for hormones, create stress, and cause women to feel like nothing will work. She emphasized that restoring balance is crucial and shared how semaglutide, can help stabilize glucose levels and create a sense of evenness, reducing anxiety around blood sugar irregularities. Understanding Semaglutide and Its Effects on Glucose Levels Semaglutide works for type II diabetes because it raises insulin initially, which is contrary to anti-insulin theories. However, it also helps lower glucose levels. Stabilizing glucose levels can help women overcome the glucose rollercoaster that they often experience. When glucose levels stabilize, the anxiety and chemical dips in blood sugar that drive hunger disappear; leading to a sense of zen detachment from food. The Role of GLP-1 in Weight Loss GLP-1 is a peptide hormone that signals satiety and fullness, which helps with weight loss. When we produce more GLP-1, it increases our sensitivity to leptin, our satiety hormone. Emily points out that we don't fully understand why some hormone signals get messed up along the way, but it's likely due to the abundance of food we have access to all the time. This abundance makes us eat as much as we can get our hands on, which causes us to ‘save up for a rainy day’ that doesn't come in modern America. It's one of the main drivers of the obesity epidemic, according to one theory. Using Semaglutide is Not a Silver Bullet After our in-depth discussion about using semaglutide for weight loss purposes, Emily cautioned that it's not a silver bullet. While it can provide significant support, she emphasizes the importance of also adopting lifestyle changes, such as reducing processed foods and sugar, and increasing healthy fats and proteins. It's also important to find a sustainable way of eating that works for you and creates balance. She reminds us that weight loss is not just about looking good but about metabolic health, longevity, and overall well-being. Is Semaglutide for Weight Management a Long-Term or Short-Term Solution? As a weight management medication, semaglutide was designed to be a long-term solution. But from the perspective of functional medicine, Emily explains, it is important to look at transitioning off the medication or moving to a small maintenance dose that may not even need to be given weekly. The goal is to promote healthy metabolic flexibility and the ability to burn fat easily, which can be achieved by working on all the other things that support weight loss and good health. What You Need to Know about Taking Semaglutide for Weight Loss Before jumping on the Ozempic bandwagon, here are the key things you need to know about semaglutide:Side Effects of SemaglutideGenerally, semaglutide is given as a weekly injection and is titrated slowly from a quarter of a milligram to the target dose of 2.4 milligrams to avoid side effects. The primary side effects that people experience are nausea, reduced appetite, anorexia, and initial fatigue. However, these side effects are usually transient, and most people can tolerate them well. Some people are more sensitive to the gastric peptides that the medication increases than others, which can cause nausea, stomach pain, or a feeling of being sick.How Long to Take SemaglutideEmily explains that typically, people are on Semaglutide for at least nine to twelve months, depending on how much weight they want to lose. The medic...

The Case:  In the last episode, we met Liana and heard all about her issues with fatigue, digestion, hair loss, joint pain, and lack of concentration. As a person living with Hashimoto’s, she knows many of these symptoms are related but was struggling to stick to the healthy routines that could make a difference. That’s why I decided to discuss her case with Hypnotherapy expert, Grace Smith. In  episode 139 of Health Mysteries Solved: Thyroid and Hashimoto’s Revealed, Grace busted the misconceptions surrounding hypnotherapy and explained so clearly how it works. I encourage you to jump back and listen to that episode before proceeding to learn how hypnotherapy can specifically help those with Hashimoto’s and how it helped Liana with her issues. Stress as a Trigger for Hashimoto’s There are four main triggers for Hashimoto’s:FoodInfection Toxins (environmental and food)Stress Of these, stress is so often overlooked. And one of the causes of stress that is easy to overlook because we may not be fully aware of is past trauma. This is where hypnosis can play a big role. Sometimes it could be big T trauma (a specific event that is easily identifiable as the source of trauma), but for others, it could even be smaller things. For example, it could be that they may have been rejected from something, or that they struggle with self-worth because of their upbringing. There's also a really big connection between shame and Hashimoto’s and inflammation in general. These small t traumas or limiting beliefs can be the stress trigger for Hashimoto’s without people realizing it.Grace explains that many of these issues develop in the subconscious before the age of 7. What’s significant about this is that the brain has not yet started to produce beta waves. And so, from seven and under, we're almost completely in the hypnotic state. This is why kids learn so quickly - our brains can easily absorb new information and make new neural pathways in the hypnotic state. However, those neural pathways and ideas we are taught at an early age, tend to stick. This is why it can be hard to change our way of thinking - especially if our brains are stuck in a beta brain state. Rewriting Childhood Neural Pathways Since many of our beliefs (limiting and otherwise) are created before the age of 7, hypnosis can help to take us back to that time and allow us to understand where these ideas come from and rewrite those neural pathways. Grace shares a great example of this in our conversation where she’s talking about a kindergarten teacher picking on someone’s drawing and how that can lead to them feeling shame, unworthiness, or even fear of being the center of attention. As kids, we have a reaction to that and it’s hard to believe that a single event can affect us years later but Grace says it can be the cause. The good news, she says, is that through hypnosis, you can go back and rewrite that script. And, by doing that, you shift those long-held beliefs and feelings. Subconscious Self-Sabotage When we looked at Liana’s case, we discovered that she had this subconscious belief that she was not worthy of good health. As a result, she couldn’t trust that feeling good would last or that it was really how she felt. That’s why she couldn’t stick with a routine - she never believed it would work, and when it started to, she couldn’t believe it would last. She didn’t think she deserved to be healthy. Grace says this is so common and something that can absolutely be addressed through hypnosis.She shares a great story about a grandmother in her late 70s who was dealing with chronic pain. Doctors and their tests could find no cause. Through hypnosis, Grace was able to get the patient into the theta brainwave state and have a conversation with the woman’s subconscious. It was here that the real cause of the pain was revealed - the woman was afraid to heal because she believed that her family visited her only because she was sick and that if she was healthy, they would not visit as frequently. In this episode, Grace reveals how she was able to rewrite this belief and have the woman come out of hypnosis no longer debilitated by pain. What Does Hypnosis Feel Like? Everyone is going to experience being in the theta brainwave state differently. Grace is quick to dismiss the ‘Hollywood’ version of hypnosis where you’re watching a movie on the inside of your eyelids. She explains that some people are more auditory while others are more kinesthetic. It’s important for anyone curious about hypnosis to keep this in mind because they may go in expecting to see something when they can simply know it or feel it and still have it be effective. When people don’t have the ‘Hollywood’ experience of being able to visualize, they can sometimes question the validity of the work. It can lead to them not believing in hypnosis. Grace says this is okay because belief is not required. The results will come whether you believe it or not. Free Sample Hypnotherapy Session Because I know people are curious about the experience of hypnotherapy, I asked Grace to help you get into the theta brainwave state. In this episode, she walks you through a simple exercise - be sure to listen in a comfortable position (and that you’re not driving or walking while doing it!)The exercise shows how effective moving into a theta brainwave state can be for reducing stress levels. Be sure to note your stress level before the exercise and then again after. This is a 5-minute exercise and most hypnotherapy sessions done by Grace or her team are 45 minutes, so this really is just a little sample of what it’s like to experience hypnotherapy. Grace also has an App where you can continue exploring the benefits of hypnotherapy. Conclusion  Taking a look at what Lianna was doing to support her thyroid, I discovered that she wasn’t clear on her thyroid type. Her thyroid type is ‘unavailable thyroid type’ which means that her thyroid was functioning but her body was unable to absorb the T3 and T4 she was producing. We were able to improve that by supporting her estrogen levels and also addressing her stress. But, much of her stress was coming from her limiting beliefs so I knew that hypnosis would help. She was game! She discovered through hypnosis that she had a subconscious belief that nobody feels good and that suffering is part of life. No wonder she didn’t feel like she deserved to be healthy!Through hypnosis, she was able to rewrite these beliefs and as a result she experienced a reduction in the pain in her joints and she had more energy. She also saw a reduction in hair loss which I think was a result of the shifts in her biochemistry as well as the hypnotherapy sessions and the self-hypnosis she is now doing. Personal Update I hope you enjoyed this conversation about hypnosis. I personally have been doing hypnotherapy and have had some major breakthroughs. In fact, I loved the process so much that I am getting my certification for hypnosis as well.  Don’t worry, I’ll still be here as your guide on your Hashimoto’s or thyroid journey - I’ll just have one more tool on my belt! For me, it’s all about getting to the root of the problem so we can heal and enjoy life. And hypnotherapy is definitely one of  the ways to get to that root. I’ll keep you posted on my progress. But remember, when it comes to your health issues, the answers really are out there. It's just a matt...

The Case:  Liana is dealing with fatigue, digestive issues, hair loss, joint pain, and lack of concentrationShe’s been diagnosed with Hashimoto’s and has been trying to eat right and take supplements to support it but can’t seem to stick with the routine. She’s struggling to find a balance that includes feeling good. The Investigation One of the things I noticed when I met with Liana was she had some limiting beliefs about her ability to feel good again and, I suspected that she was subconsciously self-sabotaging. I knew then that if we were dealing with issues on a subconscious level, we needed to start there - and more specifically with Hypnosis. Understanding Hypnosis Grace Smith is one of the world's leading hypnotherapists and I knew she was the perfect person to have on the show to address how hypnotherapy can help chronic illnesses, like Hashimoto’s, from all angles, including beliefs, fears, stressors, and traumas. Before we could dive into how it can help, we had to address the elephant in the room - the perception of hypnotherapy as a party trick that leaves people barking like a dog or strutting like a chicken. Grace has heard this all before and admits that she was skeptical herself before hypnosis helped her quit smoking. The first thing she does is dispel the myth that hypnosis is mind control. Next, she reveals the real secrets behind those hypnotist shows. Spoiler - it’s all a show!She goes on to explain that hypnotherapy is just meditation with a goal or a purpose. How Hypnosis Works Our brain waves fluctuate between several different states based on our level of consciousness. The beta state is where we spend most of our waking lives - it's the state of normal waking consciousness where we experience stress, fight or flight mode, and survival mode. Unfortunately, many people live in this state perpetually, which can be really corrosive to our physical, emotional, and mental health, as well as our relationships.There are three other brain wave states that we can access with a bit of effort. The alpha state is where we go when we're daydreaming or doing something rote like washing our hair in the shower. It's a slightly more relaxed state where we can access inspiration and intuition. The delta state is where we go when we're sleeping and our brains are essentially offline. But the most interesting state, and the one that Grace works with, is the theta state. This is where hypnotherapy takes place, and it's a state of deep relaxation where we're still consciously aware of our surroundings. In this state, we have the surplus energy required to create new neural pathways in our brain extremely rapidly, which is why hypnotherapy can be so effective. It's all about telling your brain a better story and focusing on what you want, rather than staying stuck in the same old thought patterns. How Hypnotherapy can Help with Hashimoto’s, Inflammation, and other Autoimmune Issues Through hypnotherapy, Grace Smith suggests that people can learn how to visualize their bodies healing and healthy, as well as learn how to communicate with their bodies to promote healing. By changing the way the person perceives their symptoms, they can reduce the inflammation in their body and improve their overall health. Additionally, she emphasizes the importance of identifying and addressing any emotional or mental factors that may be contributing to the inflammation and autoimmune response in the body. By helping the person relax and release emotional tension, hypnotherapy can promote a healthier immune response and reduce inflammation.In this way, hypnotherapy can help with Hashimoto's and inflammation by:Opening up access to a deep state of relaxation where rest and repair happenWeakening the neural pathways of limiting beliefs and creating new pathways for positive changeHelping promote healing through visualization of the body's healingAddressing emotional and mental factors that may be contributing to inflammation and autoimmune response in the bodyPromoting a healthier immune response to further reduce inflammationGrace shared that changes can happen fairly quickly and that the efficacy (for those who truly want to change) is very high. She said that one study found that six sessions of hypnotherapy resulted in an average of 93 % improvement per topic. The same study found that 600 sessions of talk therapy or psychotherapy, resulted in an average of 33 % improvement. This is not to say that therapy does not have value or its place in a healing journey. Amazing Healing Stories In this episode, Grace shares a whole host of amazing stories where hypnosis provided healing in ways that the patients didn’t think were possible. She got started in this field because she was fascinated by how one technique could help on so many levels, from smoking to public speaking, from eating disorders to stroke recovery. Hypnotherapy and Your Hashimoto’s Healing Journey Talking with Grace about hypnotherapy brought up so many different facets of the healing journey for anyone with Hashimoto’s including Liana. There are so many different symptoms, and there's typically a big inflammatory component and insufficient thyroid hormone. There are four main triggers with Hahsimoto’s including food, toxins, infections, and stress (including day-to-day, emotional, and past traumas). We can also experience upper limits that we hold about what we deserve or how we deserve to feel. We have stories we’ve told ourselves for so long that we don’t see them as stories, we see them as truths. For example, following a specific diet is hard or undesirable. This is where Grace says hypnotherapy can help. She shares some interesting studies relating to people with IBS and inflammation who had amazing results through hypnotherapy. One of the reasons hypnotherapy is so successful with decreasing inflammation is because it takes the body out of the stress state which creates the inflammation. She also says that hypnotherapy can help people lose their taste for processed foods and sugar, both of which contribute to inflammation and other health concerns. She says that these kinds of shifts can take between 6 and 10 sessions but that it is so often effective because your subconscious is hearing the better story of health for the first time and reframing the subconscious relationship with certain types of food or eating habits.   Diving Deeper into Hypnotherapy for Hashimoto’s - To Be Continued! There was so much in this interview with Grace, it was actually too long to get into one episode. So, we continue our conversation in episode 140 after which I’ll share what happened with Liana and how she was able to get past her struggles with Hashimoto’s. Plus, in the next episode, I’ll share everything that I have been using hypnosis for with myself and my family.  In the meantime, check out the links below to get to know Grace a bit better yourself and see if her resources can help you or someone in your life dealing with a health mystery.  Links:Resources mentionedThanks to my guest Grace Smith. You can connect with her and download her app at GetGrace.com.And you can check out her books, too:  Close Your Eyes, Get Free  Close Your Eyes, Lose Weight 

The Investigation Most Hashimoto’s diagnoses come with many mixed emotions. On one hand, there is finally an explanation for all of your many symptoms, but on the other hand, the diagnosis brings on a slew of emotions like frustration, feeling lost, and uncertainty. And, for some, it can bring a devastating sense that life will never be the same again.   I get so many questions from my community like, can I still get pregnant with Hashimoto’s? Can I have balanced hormones with Hashimoto’s? Can I ever get my energy back? Can my hair ever grow and be thick again? Can my digestive issues resolve? Can I ever get rid of my brain fog?  And the list goes on and on and on. I am here to tell you that as mysterious as many of the symptoms may seem, having Hashimoto’s doesn’t have to be a barrier to you living a good, healthy life.    My Personal Experience with Hashimoto’s I was first diagnosed at 25.  Everything was so overwhelming and I worried that my health would be compromised for the rest of my life. I was so wrong.  I was able to have children (I have 2). I have more than enough energy to take care of my young kids, run a full-time practice, and run an online business educating and supporting hundreds of students through their own Hashimoto’s journey. I’ve also been able to defy the norms of Hashimoto’s by having strong healthy hair and clear skin. I feel healthier now than I did when I was first diagnosed. My fears were unfounded and I want you to know that everything is possible. I was inspired by my friend, Hal Elrod who wrote The Miracle Equation because I believe that the first step in overcoming issues related to Hashimoto’s starts with his approach:   Believe that you can. It's that faith, that knowing (even if you fake it before you make it) that you can and you will get through this.  Take action. Continuously put in the effort to make your desired health a reality.   You need both of these for the equation to work. If one side goes, everything comes tumbling down.  You need to take action and believe that you can be healthy and feel good again.  If you need support on either part of this equation, you’ve got me in your corner. Through this podcast and, more specifically, through my Thyroid Mystery Solved free training and complete program, I’m here to help you get clear on the actions you need to take. I’m also there to help you keep the faith!    The Two-Fold Approach to Healing Hashimoto’s When it comes to what actions you need to take, the picture can be a bit confusing. There is so much conflicting information out there and so many people who feel that this or that tactic didn’t work. I know exactly why these don’t work. It’s because you have to use a two-fold approach. You cannot deal with your Hashimoto’s symptoms in a vacuum. You have to also support your immune system.  This is the most important thing to remember when you are working at improving your health with Hashimoto’s. It does not matter what you do for your Hashimoto’s if your immune system is not supported, it will continue to attack your thyroid. And, you can’t just support your immune system without addressing your Hashimoto’s symptoms if you want to see improvements in your health. The two-fold approach is the only thing I have seen work in my long experience helping clients with Hashimoto’s.    Why The Slow Road is Better for Hashimoto’s In this episode, I share the stories of two friends. These stories perfectly illustrate why, despite it being the harder path, we do sometimes have to take the slow road to recovering our health. Quick fixes seldom stick.  I know this is hard to hear when you’re suffering with Hashimoto’s but the process of working your way through your issues and drilling down until you find the root of the problem is going to mean that you land on a solution that is sustainable. Plus, you will appreciate your hard-won health and so, will respect it and continue to stay committed to maintaining it.   Your current health journey is a necessary part of your future good health. Remember to keep that faith that you can get better!   How to Get Support on Your Path to Living Healthy with Hashimoto’s As I explain in this episode, you need to both take action and you need to be steadfast in your belief that living healthy with Hashimoto’s is possible for you.  These two things helped me regain my health. That’s why, when I decided to create a program to help you overcome Hashimoto’s I included elements that address both the mindset and the specific and customized actions you need to take to regain your health.  I also created this program because I know how hard you work to try to find all of the answers. I know that you’ve hit that wall of frustration and thought, why can’t there be one place with all of the answers and a clear plan for me to follow.  I know because I’ve sat across from client after client who have said that exact thing.  I know because I’ve been there.   In this episode, I give you an overview of the Thyroid Mystery Solved program and invite you to discover for yourself what it feels like to be on your path to living healthy with Hashimoto’s instead of being stuck in that limbo of research and half efforts.  This program is different from anything you’ve found online because we start by identifying your thyroid type. This is critical because the actions you need to take are based on your thyroid type. Most other approaches are a one-size-fits-all.  Next, we look at the thyroid issue from every angle, taking into consideration all of the different systems involved. This goes beyond that two-fold approach I mentioned earlier - it is far more extensive.  Yes, the program does cover diet (it even includes meal plans and recipes), exercise, mindset, and how to support your different systems and organs that is specific to you and your thyroid type. Plus, you will uncover and solve your specific Hashimoto’s triggers (this will be different for everyone which is another reason why we don’t want a one size fits all approach and why its so important for things to be customized) You will also have access to me.  I don’t mind sharing that this is one of the ONLY ways that you can get access to me because my practice calendar is full and I am not able to take new clients. You can jump the queue and have access to me directly through this program. I think this is also where so much of the value of the program comes from. Maybe you’ve already paid for doctor visits that resulted in more frustration. Maybe you’ve even gone to see an integrative doctor and paid to get one or two answers. Now imagine having access to me for all of your questions. How many hundreds of dollars will you save getting your questions answered through the program instead of having to pay for each one?  It’s an incredibly extensive program that is totally customized to you and your journey. That’s the best part; YOUR path is clearly laid out for you so that all you have to do is take action and believe that you can get better. And I’ll be there to keep you on track.  No more wasting hours searching for answers. No more half measures that get you a fraction of the result you want. No more feeling hopeless and overwhelmed. 

The Case:  Alison has Hypothyroidism and Hashimoto’s and also experiences tons of digestion issues. She often feels gassy and bloated and has trouble going to the bathroom.She’s tried taking all types of probiotics, eating super nutritious fermented foods, and done several colon cleanses, but nothing helped.  The InvestigationWhen I met Alison, she explained that she had taken gut-support vitamins and eaten a healthy diet. However, I could see right away that she was missing a few big clues in solving her health mystery.  Gluten, Gut Health, and Hashimoto’s I’ve talked a lot about the connection between Hashimoto’s and our gut on the podcast in the past. I knew that this was at the core of solving Alison’s issues. To discuss it further, I invited Dr. Vincent Pedre, aka America's Gut Doctor, to the show.  Dr. Pedre is an internist and the author of the upcoming book The Gutsmart Protocol. One of the first things he brings up is the connection between Hashimoto’s and gut health as well as gluten. We’ve talked a lot about this connection on the Health Mysteries Solved podcast - including my own journey with Hashimoto’s and gluten. Dr. Pedre shared the work of Alessio Fasano, who studied the effects of gluten on the gut and how gluten can trigger autoimmunity. He discovered that gluten triggers the release of a protein called Zonulin, which increases gut permeability. This leads to leaky gut, which can eventually result in autoimmunity. Dr. Pedre also explained that there are three key factors in the development of autoimmune diseases: genetic predisposition, environmental triggers (such as gluten), and leaky gut.He went on to explain that one of the enzymes that helps break down gluten, called tissue transglutaminase, can create a chimeric molecule that can be recognized by the body's immune system as an invader. This can lead to an antibody response and cross-reactivity, especially with the thyroid where tissue transglutaminase is found in high concentration. The Power of a Food Journal One of the best ways to solve a health mystery involving gut health is to keep track of everything that is being eaten. Dr. Pedre uses this technique to help him diagnose issues but also finds that the activity really helps patients better understand their own triggers. So often we are unaware of all of the things we put in our mouth - especially when we don’t know all of the ingredients in the food we eat. Dr. Pedre shared a powerful story about one of his patients having a complete epiphany after keeping a food journal for just a few days. This mindful practice helps us better connect with our eating and be better advocates for our own health. It reminds us that everything we eat is feeding our microbiome. Balancing the Microbiome is Complex  Many people think that the answer to balancing the microbiome is to take a probiotic, but Dr. Pedre explains that it’s far more complex than that. And, because our microbiome controls so many aspects of our health, it’s imperative that we keep it balanced. He explains that, while probiotics are helpful, they are just a small part of the bigger picture. His approach has changed over the years - he used to be quite aggressive in attacking the bad bugs but now he has a more holistic approach. This means looking at the person as a whole, their history, reactions to different things, and taking a gut-body-mind-spirit approach to healing. We’ve discussed this many times on the show (if you want a good overview, check out episode 112). The gut health issue is just a portal into something much bigger and it's important to approach it holistically.One of the keys to a holistic approach is to understand what is actually going on. Dr. Pedre will sometimes use stool testing but warns that it can be misleading. Instead, he looks at different types of gut issues, which I love because it has been such a successful way for me to help people with thyroid conditions. We both agree that a one-size-fits-all approach rarely works. There are so many things that could be at play in the gut issue including dysbiosis, yeast overgrowth, histamine issues, enzyme deficiency, leaky gut, damaged epithelium,  SIBO or SIFO - and each of these will impact tolerance of probiotics and fermented foods. Could Toning the Vagus Nerve Be the Answer? Dr. Vincent Pedre revealed a fascinating connection between the vagus nerve (also known as the vegal nerve) and our gut health issues. He explains that stress is a huge factor in affecting the vagus nerve, which is essentially the connection between the brain and internal organs, with the majority of communication being directed from the gut to the brain.As you know if you’ve listened to my past episodes, stress in our lives can seriously impact our health. We often think of our mental health when we think of stress but it can cause biophysical stress. This can affect the vagus nerve which can impact our digestive processes. To get the body back to a state of relaxation and proper digestion, it is important to activate the vagus nerve through exercises and mindfulness practices. Dr. Pedre recommends deep breathing exercises where you breathe in and then exhale with a hum (or ‘Ohm’ sound). Dr. Pedre also stresses the importance of understanding the interconnectedness of the gut microbiome and the vagal nerve, as the gut microbiome stimulates vagal nerve receptors and sends signals back to the brain. He highlights that in order to achieve optimal gut health, one must address all aspects of the holistic healing plan, including stress levels, and not just focus on diet and supplements. Solving Digestion Issues is not One-Size-Fits-All Just like I always say about healing autoimmune issues (like Hashimoto’s), the solution is never one-size-fits-all. There are so many factors at play and the same is true with digestive issues. This is especially true when it is in combination with autoimmunity and thyroid health. We have to look at it from all angles and customize the solution as much as possible. This is what we did with Alison. First, we assessed what was going on. Alison was taking lots of vitamins and eating a ton of fermented foods. This can be great but they do not work for everyone. In fact, fermented foods can sometimes make things worse because of other imbalances in the gut. To get started, we removed those highly fermented foods and started her on a low histamine diet. We ran a Vibrant Zoomers test, genetic tests and a stool test. The results revealed that gluten was an issue for her – all of the things she was taking to heal her gut were being undone by her gluten consumption. We saw that she had SIBO, and the probiotics she was taking were making it worse because her body wasn’t able to handle them. This is a classic case of doing ‘all the healthy things’ that turn out to be the wrong things for the individual. Next Steps Alison was also always in a rush and didn’t take much time to eat so we worked on slowing down. She also created more time for her. Stress increases our cortisol levels (that’s why it’s called the stress hormone) which, in turn, impacts our immune system and gut health. We supported Alison’s stress through lifestyle adjustments and the supplement