Original airdate: 10/11/2010Fifteen years after the O.J. Simpson trial, Oprah goes one-on-one with former LAPD detective Mark Fuhrman about the trial as they discuss the key players, the evidence, and his shocking revelations. He also discusses how the case affected his life and what would happen if he met O.J. face to face.

Original Airdate: 01/28/2011Fran Drescher and her ex-husband Peter Jacobson discuss their relationship and Peter's subsequent coming out as a gay man. Oprah also revisits some of her most memorable guests, including Geno Jones, who put out a personal ad 17 years ago looking for the perfect woman; John and Rochelle, who is one of the most controlling wives in the history of the show; Michelle Kramer, whose husband, Dr. Mark Weinberger, disappeared from their yacht in the Greek isles and was later found hiding in a tent in the Italian Alps; Trina, who appeared on an earlier show with her now ex-husband who said he was no longer attracted to her because she had gained weight; and David and Elizabeth Weinlick, who married on the day they met at the Mall of America.

Original Airdate: 10/06/2010An unforgettable guest, Truddi Chase, originally brought the diagnosis “Multiple Personality” to our attention on The Oprah Winfrey Show in 1990 . Discover what happened to her and hear her daughter describe what life was like inside their home. Then, meet Kim Noble, a mom with 20 personalities. 

Airdate: 09/22/2010Oprah talks to Ingrid Betancourt, who was kidnapped at gunpoint and held captive for six-and-a-half years in the jungle. Ingrid discusses her captivity and the book she wrote about her ordeal, "Even Silence Has an End." Ingrid was a Presidential candidate in Colombia when she was abducted by FARC rebels and held captive in the Amazon jungle.

Airdate: 09/17/2010Oprah, Nate Berkus, and Vera Wang help make some over-the-top ultimate wildest dreams come true for some of the most loyal Oprah Show viewers, including a single mother, a group of unsuspecting brides, and one of Oprah's all-time favorite guests, the amputee warrior mom.

From May 20th, 2004Oprah talks with people who have made mistakes that they cannot take back. Oprah speaks with a teen student who had an affair with her coach; a son who accidentally killed his mom while drag racing and the mother whose daughter died and her son was injured after not using a car seat.

From July 16th, 1993Oprah speaks with Andrew Vachss, an attorney exclusively representing children and youth. He is also the author of Another Chance To Get It Right, a children's book for adults that explores the realities of child abuse and juvenile violence. They discuss Oprah's own experience with abuse and the abuse happening to other children. Andrew Vachss passed away on November 23rd, 2021 at the age of 79.

From October 6th, 2008: A son masterminds the murder of his family. Now, Lisa Ling visits death row for an exclusive interview. Plus, why the father who was supposed to die forgives his son.

From March 29th, 2010: At 69, find out how legendary model, Golden Globe winning actress and sex symbol, Raquel Welch is aging brilliantly. Plus, she helps one 64-year-old grandmother get her mojo back.

From January 29th, 2008: Author and world renowned security specialist Gavin de Becker is widely regarded as America's leading expert on protecting public figures, including former Presidents. Today he talks about his book, The Gift of Fear, discussing the signals that occur before violence and how trusting your intuition can help save your life.