Breathe Easy

A discussion of vaccine information, hesitancy and uptake among multiple populations and how we can improve uptake in our daily practices Show ReferencesMcElfish PA, Willis DE, Shah SK, Bryant-Moore K, Rojo MO, Selig JP. Sociodemographic Determinants of COVID-19 Vaccine Hesitancy, Fear of Infection, and Protection Self-Efficacy. J Prim Care Community Health. Jan-Dec 2021;12:21501327211040746. doi:10.1177/21501327211040746 MacDonald NE, Hesitancy SWGoV. Vaccine hesitancy: Definition, scope and determinants. Vaccine. Aug 14 2015;33(34):4161-4. doi:10.1016/j.vaccine.2015.04.036 Nguyen LH, Joshi AD, Drew DA, et al. Racial and ethnic differences in COVID-19 vaccine hesitancy and uptake. medRxiv. Feb 28 2021;doi:10.1101/2021.02.25.21252402 Wong LP, Alias H, Danaee M, et al. COVID-19 vaccination intention and vaccine characteristics influencing vaccination acceptance: a global survey of 17 countries. Infect Dis Poverty. Oct 7 2021;10(1):122. doi:10.1186/s40249-021-00900-w Jacobson RM, St Sauver JL, Finney Rutten LJ. Vaccine Hesitancy. Mayo Clin Proc. Nov 2015;90(11):1562-8. doi:10.1016/j.mayocp.2015.09.006 S. B. Omer, D. A. Salmon, W. A. Orenstein, M. P. deHart and N. Halsey. Vaccine Refusal, Mandatory Immunization, and the Risks of Vaccine-Preventable Diseases. NEJM 2009 Vol. 360 Issue 19 Pages 1981-1988 Lila J. Finney Rutten, Xuan Zhu, Aaron L. Leppin, Jennifer L. Ridgeway, Melanie D. Swift, Joan M. Griffin, Jennifer L. St Sauver, Abinash Virk, Robert M. Jacobson. Evidence-Based Strategies for Clinical Organizations to Address COVID-19 Vaccine Hesitancy. Mayo Clinic Proceedings. Volume 96, Issue 3. 2021. Pages 699-707. Raymond John D Vergara, Philip Joseph D Sarmiento, James Darwin N Lagman, Building public trust: a response to COVID-19 vaccine hesitancy predicament, Journal of Public Health, Volume 43, Issue 2, June 2021, Pages e291–e292, https://doi.org/10.1093/pubmed/fdaa282 Corbie-Smith G. Vaccine Hesitancy Is a Scapegoat for Structural Racism. JAMA Health Forum. 2021;2(3):e210434. doi:10.1001/jamahealthforum.2021.0434The 'successful failures' of Apollo 13 and Covid-19 vaccination - STAT (statnews.com)

Tidal Volume is a podcast from ATS Peds focusing on core concepts of pediatric pulmonology. The goal is to bring in depth focus on these core concepts for residents, fellows, early career pulmonologists or even senior faculty looking for a refresher.In episode 7, Ryan Thomas MD from Michigan State University discusses tracheobronchitis in children with tracheostomy tubes with Dan Craven MD and Moshe Prero MD from Case Western Reserve University/Rainbow Babies and Children’s Hospital and Alexander Gipsman MD from Children’s Hospital  of Philadelphia. We discuss their review article Tracheobronchitis in children with tracheostomy tubes: Overview of a challenging problem and why they decided to write on this topic.  We also discuss the importance of tracheobronchitis in this patient population, the risk factors for infection, the microbiology of the airway,  and the diagnosis and treatment of tracheobronchitis in children with tracheostomy tubes.  Guests:  Daniel Craven, MD, Case Western Reserve UniversityMoshe Prero, MD, Case Western Reserve UniversityAlexander Gipsman, MD, Children's Hospital of Philadelphia Host:  Ryan Thomas, MD,  Michigan State University ReviewersChristina Barreda, MD, University of Wisconsin Elizabeth Fiorino, MD, Hofstra University Production/EditingRyan Thomas, MD,  Michigan State University Contact Information:TidalVolumeATSPeds@gmail.com Twitter Accounts:Ryan Thomas, MD@MSUPedsPulm@ATSPeds References Gipsman A, Prero M, Toltzis P, Craven D. Tracheobronchitis in children with tracheostomy tubes: Overview of a challenging problem. Pediatr Pulmonol. 2022 Apr;57(4):814-821.Akangire G, Manimtim W, Nyp M, et al. Factors leading to rehospitalization for tracheostomized and ventilator-dependent infants through 2 years of age. J Perinatol. 2017;37(7):857-863.Horan TC, Andrus M, Dudeck MA. CDC/NHSN surveillance definition of health care-associated infection and criteria for specific types of infections in the acute care setting. Am J Infect Control. 2008;36(5):309-332. Griese M, Felber J, Reiter K, et al. Airway inflammation in children with tracheostomy. Pediatr Pulmonol. 2004;37(4):356-361. Willson DF, Conaway M, Kelly R, Hendley JO. The lack of specificity of tracheal aspirates in the diagnosis of pulmonary infection in intubated children. Pediatr Crit Care Med. 2014;15(4):299-305. Cline JM, Woods CR, Ervin SE, Rubin BK, Kirse DJ. Surveillance tracheal aspirate cultures do not reliably predict bacteria cultured at the time of an acute respiratory infection in children with tracheostomy tubes. Chest. 2012;141(3):625-631. Rusakow LS, Guarín M, Wegner CB, Rice TB, Mischler EH. Suspected respiratory tract infection in the tracheostomized child: the pediatric pulmonologist's approach. Chest. 1998;113(6):1549-1554. Goldstein I, Wallet F, Nicolas-Robin A, Ferrari F, Marquette CH, Rouby JJ. Lung deposition and efficiency of nebulized amikacin during escherichia coli pneumonia in ventilated piglets. Am J Respir Crit Care Med. 2002;166(10):1375-1381. Herrmann G, Yang L, Wu H, et al. Colistin-tobramycin combinations are superior to monotherapy concerning the killing of biofilm Pseudomonas aeruginosa. J Infect Dis. 2010;202(10):1585-1592. Tamma PD, Turnbull AE, Milstone AM, Lehmann CU, Sydnor ER, Cosgrove SE. Ventilator-associated tracheitis in children: does antibiotic duration matter? Clin Infect Dis. 2011;52(11):1324-1331. Chastre J, Wolff M, Fagon JY, et al. Comparison of 8 vs 15 days of antibiotic therapy for ventilator-associated pneumonia in adults: a randomized trial. JAMA. 2003;290(19):2588-2598. Silva RC, Ojano-Dirain CP, Antonelli PJ. Effectiveness of pediatric tracheostomy tube cleaning. Arch Otolaryngol Head Neck Surg. 2012;138(3):251-256. Morrison JM, Hassan A, Kysh L, Dudas RA, Russell CJ. Diagnosis, management, and outcomes of pediatric tracheostomy-associated infections: A scoping review. Pediatr Pulmonol. 2022 May;57(5):1145-1156. Jutras C, Autmizguine J, Chomton M, et al. Inhaled antibiotics for the prevention of respiratory tract infections in children with a tracheostomy. Front Pediatr. 2021;9:633039.

In this “Breathe Easy Critical Perspective” podcast, Dr. Dominique Pepper interviews Dr. Nina Andersen-Ranberg. They discuss her recent RCT published in the NEJM investigating haloperidol for delirium in ICU patients. Dr. Andersen-Ranberg is a physician undergoing her PhD training in Anesthesiology in Zealand University Hospital, Køge Denmark.

In this “Breathe Easy Critical Perspective” podcast, Dr. Dominique Pepper interviews Dr. Laurent Brochard. They discuss his recent NEJM publication reviewing non-invasive respiratory support in critically ill adults. Dr. Brochard is the Director of the Interdepartmental Division of Critical Care Medicine, University of Toronto, Canada and the Deputy Editor of the Blue Journal.

In this “Breathe Easy Critical Perspective” podcast, Dr. Dominique Pepper interviews Dr. William Checkley. They discuss outcomes in critically ill patients with pneumonia due to SARS-CoV-2 compared to other etiologies. Dr. Checkley is an Associate Professor of Medicine in the Division of Pulmonary and Critical Care at the Johns Hopkins School of Medicine, Baltimore Maryland.

Integrating advanced communication, symptom management and early Palliative Medicine

In this “Breathe Easy Critical Perspective” podcast, Dr. Dominique Pepper interviews Dr. Alisa Higgins. They discuss long-term outcomes in critically ill patients with COVID-19. Dr. Higgins is Senior Research Fellow at Monash University in Melbourne, Australia.

References:  Roy-Chowdhuri S, Dacic S, Ghofrani M, Illei PB, Layfield LJ, Lee C, Michael CW, Miller RA, Mitchell JW, Nikolic B, Nowak JA, Pastis NJ Jr, Rauch CA, Sharma A, Souter L, Billman BL, Thomas NE, VanderLaan PA, Voss JS, Wahidi MM, Yarmus LB, Gilbert CR. Collection and Handling of Thoracic Small Biopsy and Cytology Specimens for Ancillary Studies: Guideline From the College of American Pathologists in Collaboration With the American College of Chest Physicians, Association for Molecular Pathology, American Society of Cytopathology, American Thoracic Society, Pulmonary Pathology Society, Papanicolaou Society of Cytopathology, Society of Interventional Radiology, and Society of Thoracic Radiology. Arch Pathol Lab Med. 2020 May 13. doi: 10.5858/arpa.2020-0119-CP. Epub ahead of print. PMID: 32401054. Yatabe Y, Dacic S, Borczuk AC, Warth A, Russell PA, Lantuejoul S, Beasley MB, Thunnissen E, Pelosi G, Rekhtman N, Bubendorf L, Mino-Kenudson M, Yoshida A, Geisinger KR, Noguchi M, Chirieac LR, Bolting J, Chung JH, Chou TY, Chen G, Poleri C, Lopez-Rios F, Papotti M, Sholl LM, Roden AC, Travis WD, Hirsch FR, Kerr KM, Tsao MS, Nicholson AG, Wistuba I, Moreira AL. Best Practices Recommendations for Diagnostic Immunohistochemistry in Lung Cancer. J Thorac Oncol. 2019 Mar;14(3):377-407. doi: 10.1016/j.jtho.2018.12.005. Epub 2018 Dec 18. PMID: 30572031; PMCID: PMC6422775. Sehgal IS, Gupta N, Dhooria S, Aggarwal AN, Madan K, Jain D, Gupta P, Madan NK, Rajwanshi A, Agarwal R. Processing and Reporting of Cytology Specimens from Mediastinal Lymph Nodes Collected using Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration: A State-of-the-Art Review. J Cytol. 2020 Apr-Jun;37(2):72-81. doi: 10.4103/JOC.JOC_100_19. Epub 2020 Apr 2. PMID: 32606494; PMCID: PMC7315917. Wahidi MM, Herth F, Yasufuku K, Shepherd RW, Yarmus L, Chawla M, Lamb C, Casey KR, Patel S, Silvestri GA, Feller-Kopman DJ. Technical Aspects of Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration: CHEST Guideline and Expert Panel Report. Chest. 2016 Mar;149(3):816-35. doi: 10.1378/chest.15-1216. Epub 2016 Jan 12. PMID: 26402427.

A practical case-based approach to the selection of intravenous fluids in the ICU.

In this “Breathe Easy Critical Perspective” podcast, Dr. Dominique Pepper interviews Dr. Yahya Shehabi. They discuss sedation with dexmedetomidine and propofol in critically ill patients. Dr. Shehabi is Professor of Medicine at Monash University (Australia).