Breathe Easy

In this “Breathe Easy Critical Perspective” podcast, Dr. Dominique Pepper interviews Dr. Simon Finfer. They discuss Dr. Finfer's recent 2022 publication in the NEJM about balanced crystalloids versus saline in critically ill adults. Dr. Finfer is a founding member of the ANZICS clinical trials group and the Director of Intensive Care at Sydney Adventist Hospital in Australia.

Podcast CreditsWriter: Ryan Thomas, MDProducer: Ryan Thomas, MDReviewers: Christina Barreda, MDElizabeth Fiorino, MDReferences:Andreeva AV Regulation of surfactant secretion in alveolar type II cells 2007 AmJPhyLungBanfi C, Agostoni P. Surfactant protein B: From biochemistry to its potential role as diagnostic and prognostic marker in heart failure. Int J Cardiol. 2016 Oct 15;221:456-62Chroneos ZC, et al. Pulmonary surfactant: an immunological perspective. Cell Physiology and Biochemistry 2010; 25: 13-26.Cole FS, Nogee LM, Hamvas A. Defects in surfactant synthesis: clinical implications. Pediatr Clin N Am 2006; 53: 911-927.Guillot-Alveolar epithelial cells Master regulators of lung homeostasis 2013 IntJBiochemCellBioFrerking I, et al. Pulmonary surfactant: functions, abnormalities, and therapeutic options. Intensive Care Med 2001; 27: 1699-1717.Herzog EL Knowns and Unknowns of the Alveolus PROCATS57778Mason RJ. Biology of alveolar type II cells-2006-RespirologyMurray and Nadel's Textbook of Respiratory Medicine 5th ed. Accessed via MDConsult.Nathan N Surfactant protein A: A key player in lung homeostasis IntJBioCellBio 2016Nkadi PO, et al. An overview of pulmonary surfactant in the neonate: genetics, metabolism, and the role of surfactant in health and disease. Mol Genet Metab 2009; 97: 95-101.Whitsett JA, Wert SE, Weaver TE. Alveolar surfactant homeostasis and the pathogenesis of pulmonary disease. Annual Review of Medicine 2010; 61: 105-119.Wert SE, Whitsett JA, Nogee LM. Genetic disorders of surfactant dysfunction. Pediatr Dev Pathol. 2009; 12(4): 253-274.

HostSiva Bhavani, Emory UniversityGuestDavid Furfaro, BIDMC More Information: ATS COVID-19 Resource Center

GuestsProfessor Marie Williams,  University of South Australia Assoc Professor Kylie Johnston,  University of South AustraliaHostDr Hayley Lewthwaite, The University of NewcastleResourcesBreathlessness Intervention ServiceManaging BreathlessnessChronic Breathlessness Explanations and Research Priorities: Findings From an International Delphi Survey

Guest  Dr. Terese HammondICU Medical Director at Providence St. John’s Hospital, Santa Monica, California and CMO, Director and Founder of Sound Center of Research ExcellenceHost  Dr. Haala RokadiaTele-ICU Program Director at Sound Physicians, Houston, Texas

GuestJennifer Wescoe Singley, M.Ed., NCCFounder and Executive DirectorWescoe Foundation for Pulmonary FibrosisHostDr Patricia Fogelman DNP, ACHPNSystem Director, Palliative Medicine, Guthrie Clinic; Sayre PA

HostSiva BhavaniEmory UniversityGuestLaura EvansUniversity of Washington

HostDr. Alex JenkinsPostdoctoral Research Fellow, McGill University, Montreal, Canada GuestProf. Pierantonio LavenezianaPulmonologist & Professor of Respiratory Medicine, Sorbonne Université, Paris, France 

GuestSarah Viehbeck, PhDAssociate Vice President, Research Programs - Strategy at CIHR. HostSana Siddiqui, PhDon behalf of the Respiratory Structure & Function Assembly 

GuestsNaftali KaminksiYaleSara AssafUniversity of New MexicoPuneet GarchaBaylor College of MedicineHostMarc Gauthier University of Pittsburgh