The Psychedelic Podcast

Third Wave
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Sep 22, 2025 • 57min

Sterling Cooley - Xenon as Medicine: Exploring the Psychedelic Noble Gas

Sterling Cooley, a researcher and biotech entrepreneur, dives into the fascinating world of xenon, a noble gas with potential psychedelic-like effects. He shares how a personal health crisis led him to explore the therapeutic properties of xenon over other anesthetics like nitrous oxide and ketamine. Sterling explains its connection to microtubules and consciousness, discussing euphoria and visionary experiences reported by users. The conversation also touches on harm reduction and safe practices for exploring xenon’s unique effects.
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Sep 15, 2025 • 54min

Lana Pribic - Getting to the Root: Iboga, Kanna, and Africa’s Primordial Medicines

Lana Pribic, an ICF Professional Coach and co-founder of Kanna Wellness, dives deep into the world of African medicinal plants, iboga and kanna. She emphasizes the importance of preparation and patience when working with these powerful substances. Lana shares her transformative experiences with iboga during retreats, highlighting its unique effects compared to traditional psychedelics. The conversation also touches on the cultural roots of these medicines and how kanna serves as a gentle ally for daily well-being.
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7 snips
Sep 8, 2025 • 56min

Jonny Miller - Nervous System Mastery: Preparing the Body for Psychedelic Work

Jonny Miller, founder of Nervous System Mastery and host of the Curious Humans podcast, dives deep into the transformative power of nervous system regulation. He shares his journey through grief and psychedelics, highlighting the importance of emotional fluidity and creating a safe space for healing. The conversation explores how high performers can shift from burnout to creativity and the significant role of relational health in this process. Jonny also discusses practical tools for self-regulation, blending insightful anecdotes with evidence-based practices.
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Sep 1, 2025 • 53min

Brian Tierney, Ph.D. - Visionary Somatics: Psychedelics, Trauma & the Dreaming Body

In this engaging discussion, Dr. Brian Tierney, a licensed somatic psychologist and neuroscience professor, explores the fascinating merger of somatics and neuroscience. He explains how trauma disrupts brain network coordination and emphasizes the importance of body work in healing. The conversation dives into the dangers of spiritual bypassing, the role of imagination in recovery, and reflects on the balance needed to navigate transformative psychedelic experiences. Tierney also shares insights on the intriguing connections between psychedelics, extraterrestrial archetypes, and personal transformation.
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Aug 25, 2025 • 1h 11min

James Fadiman, Ph.D. & Jordan Gruber, J.D. - The Power of Less: Microdosing for Mood, Energy, and Clarity

James Fadiman, Ph.D., the 'father of microdosing', and Jordan Gruber, J.D., a writer and former attorney, delve into the transformative potential of microdosing psychedelics. They explore how microdosing enhances mood, energy, and creativity while challenging traditional pharmaceutical approaches. The discussion covers personal experiences, healing benefits, and calls for increased research into microdosing's efficacy for mental health. Their work ignites curiosity about a holistic future where psychedelics could revolutionize our understanding of wellness.
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Aug 18, 2025 • 55min

Mariah Gannessa - Reclaiming Reverence: Hapé, Healing, and the Ethics of Plant Medicine

Mariah Gannessa, founder of Four Visions and a dedicated plant medicine advocate, shares her transformative journey with the Inga tribe of Colombia. She discusses the ethics of cultural exchange versus appropriation in indigenous plant medicine. Mariah elaborates on the concept of sacred reciprocity, emphasizing how Four Visions reinvests in indigenous communities. The conversation also highlights the healing potential of traditional practices like Hapé, Mambé, and Ambil, fostering a profound respect for nature's interconnectedness and ancestral healing.
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Aug 11, 2025 • 1h 3min

Mike Jay - Free Radicals: How Nitrous Oxide Galvanized Psychedelic Science

In a captivating discussion, Mike Jay, a British author and cultural historian, delves into the transformative history of nitrous oxide in psychedelic science. He reveals how 19th-century figures like Humphry Davy paved the way for modern psychedelic thought. The conversation navigates through indigenous traditions and colonial perceptions of psychedelics, highlighting the clash between grassroots healing and institutional control. Mike also examines the cultural revolution sparked by psychedelics, advocating for a balance between clinical and community-centered approaches to mental health.
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Aug 4, 2025 • 58min

Brian Robertson - The Church With No Doctrine: Rethinking Power in Psychedelic Spaces

Brian Robertson, the creator of Holacracy and founder of Ledgeway Sangha, shares profound insights on building community through psychedelics. He discusses the unique model of the Ledgeway Sangha, emphasizing peer-to-peer healing without rigid doctrines. Brian explores the transformative journey of integrating Holacracy in spiritual contexts, shedding light on legal challenges faced by psychedelic churches. He also highlights the power of love and acceptance in fostering genuine community connections while advocating for a shift towards more inclusive spiritual practices.
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Jul 28, 2025 • 56min

Vassily Eliopoulos, M.D. - The Healing Future: Stem Cells, Psychedelics & Regenerative Therapies

Dr. Vassily Eliopoulos, co-founder and Chief Medical Officer of Longevity Health, explores the transformative potential of combining psychedelics, stem cells, and regenerative therapies. He candidly discusses his shift from emergency medicine to a holistic approach, influenced by his health journey and the limitations of traditional healthcare. The conversation illuminates how chronic inflammation and stress play key roles in modern diseases and why psychedelics might be critical in reversing these conditions. Vass also critiques medical training's focus on pathology, advocating for a proactive, patient-centered health paradigm.
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Jul 25, 2025 • 55min

Dave Rabin M.D., Ph.D. - Microdosing on SSRIs? A Psychiatrist’s Take

Dr. Dave Rabin, a board-certified psychiatrist and neuroscientist, dives into the intricate relationship between SSRIs and psychedelics. He discusses why mixing these treatments can be perilous, emphasizing the risks of serotonin syndrome. Dr. Rabin highlights the role of psychedelics in managing emotional range and the importance of tapering off SSRIs safely. He also explores specific psilocybin strains beneficial for anxious clients and shares practical tools for regulating the nervous system during withdrawal, paving the way for safer psychedelic integration in mental health.

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