The Psychedelic Podcast

Third Wave
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Aug 11, 2025 • 1h 3min

Mike Jay - Free Radicals: How Nitrous Oxide Galvanized Psychedelic Science

In a captivating discussion, Mike Jay, a British author and cultural historian, delves into the transformative history of nitrous oxide in psychedelic science. He reveals how 19th-century figures like Humphry Davy paved the way for modern psychedelic thought. The conversation navigates through indigenous traditions and colonial perceptions of psychedelics, highlighting the clash between grassroots healing and institutional control. Mike also examines the cultural revolution sparked by psychedelics, advocating for a balance between clinical and community-centered approaches to mental health.
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Aug 4, 2025 • 58min

Brian Robertson - The Church With No Doctrine: Rethinking Power in Psychedelic Spaces

Brian Robertson, the creator of Holacracy and founder of Ledgeway Sangha, shares profound insights on building community through psychedelics. He discusses the unique model of the Ledgeway Sangha, emphasizing peer-to-peer healing without rigid doctrines. Brian explores the transformative journey of integrating Holacracy in spiritual contexts, shedding light on legal challenges faced by psychedelic churches. He also highlights the power of love and acceptance in fostering genuine community connections while advocating for a shift towards more inclusive spiritual practices.
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Jul 28, 2025 • 56min

Vassily Eliopoulos, M.D. - The Healing Future: Stem Cells, Psychedelics & Regenerative Therapies

Dr. Vassily Eliopoulos, co-founder and Chief Medical Officer of Longevity Health, explores the transformative potential of combining psychedelics, stem cells, and regenerative therapies. He candidly discusses his shift from emergency medicine to a holistic approach, influenced by his health journey and the limitations of traditional healthcare. The conversation illuminates how chronic inflammation and stress play key roles in modern diseases and why psychedelics might be critical in reversing these conditions. Vass also critiques medical training's focus on pathology, advocating for a proactive, patient-centered health paradigm.
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Jul 25, 2025 • 55min

Dave Rabin M.D., Ph.D. - Microdosing on SSRIs? A Psychiatrist’s Take

Dr. Dave Rabin, a board-certified psychiatrist and neuroscientist, dives into the intricate relationship between SSRIs and psychedelics. He discusses why mixing these treatments can be perilous, emphasizing the risks of serotonin syndrome. Dr. Rabin highlights the role of psychedelics in managing emotional range and the importance of tapering off SSRIs safely. He also explores specific psilocybin strains beneficial for anxious clients and shares practical tools for regulating the nervous system during withdrawal, paving the way for safer psychedelic integration in mental health.
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Jul 21, 2025 • 59min

Dr. Dan Engle - Neuroplasticity Explained: How Psychedelics Heal the Brain

Dr. Dan Engle, a psychiatrist and neurologist, pioneers integrative medicine through his work with psychedelics. He shares his healing journey from traumatic brain injuries and explores how psychedelics enhance neuroplasticity, aiding in addiction recovery and mental health. Engle emphasizes the importance of belief, awe, and community in the healing process, while also highlighting lessons psychiatry can learn from shamanic practices. He discusses ceremonial healing and the transformative power of these experiences, connecting spirituality with modern therapeutic approaches.
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9 snips
Jul 18, 2025 • 59min

Robin Carhart-Harris, Ph.D. - SSRIs vs. Psychedelics: From Blunting to Rebooting

Dr. Robin Carhart-Harris, a leading neuropharmacologist and professor at UCSF, dives into the brain's response to SSRIs versus psychedelics. He reveals how psychedelics like psilocybin can reboot emotional processing while SSRIs often blunt it. The discussion touches on groundbreaking studies showing psilocybin's potential to treat resistant depression. John Downs, a microdosing advocate, emphasizes policy reforms for broader microdosing access. They explore neuroplasticity and the intricate changes in the brain brought by these alternative therapies.
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Jul 14, 2025 • 51min

J. Ashley T. Booth, LCSW, MS - The Anatomy of Inner Safety: IFS, Psychedelics & Trauma-Informed Healing

J. Ashley T. Booth, LCSW, MS, is a therapist, psychedelic pioneer, and author of "Quieting the Storm Within." She discusses her journey from community activism to her influential work with psychedelics like MDMA and ketamine in treating PTSD. Ashley introduces Internal Family Systems (IFS) therapy, using metaphors like clouds and sun to explain inner conflicts. She emphasizes the healing potential of psychedelics and compassionate integration of self, while sharing insights from her new illustrated guide aimed at enhancing emotional exploration.
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Jul 7, 2025 • 1h 12min

Manvir Singh - Decoding Shamanism: Psychedelics, Power, and the Architecture of Ritual

In this discussion, Manvir Singh, an anthropologist and author, shares his rich experiences from fieldwork with the Mentawai people and Yopo shamans. He dives into how shamanism serves as a psychological tool for navigating uncertainty and catalyzing healing. The conversation critiques the history of psychedelic use and highlights the tension between traditional practices and modern neo-shamanism. Listeners will also learn about the cultural significance of Yopo and the complexities faced by shamans in a changing world.
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Jun 30, 2025 • 50min

Natalie Baird-King - Facing the Unforgivable: Ayahuasca, Childhood Trauma & Self-Compassion

In this discussion, Natalie Baird-King, a board-certified attorney and author of 'Forgiving Unforgivable,' shares her powerful journey of healing from childhood trauma using ayahuasca. She introduces her HOPE model for forgiveness, emphasizing the importance of self-compassion. Natalie delves into how her psychedelic experiences reshaped her legal practice, fostering empathy and compassion in mediation. With captivating storytelling, she inspires others to embrace forgiveness as a path to personal freedom, while addressing the stigma around psychedelics in professional settings.
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Jun 24, 2025 • 60min

Rachel Pastor & Tiffany Hurd - Microdosing for Real Life: Parenting, PTSD, and Professional Growth

Rachel Pastor and Tiffany Hurd, co-founders of Golden Rule Mushrooms, explore the transformative powers of microdosing psychedelics. Rachel shares her journey from heroin addiction to advocating for healing through psychedelics. Tiffany discusses her role in guiding people through intentional microdosing for personal and professional growth. They delve into the evolving legal landscape of psychedelics, the challenges of running a responsible microdosing company, and how mindfulness can enhance emotional wellbeing. This conversation redefines perceptions of psychedelics in society.

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