Astral Codex Ten Podcast

Link: https://slatestarcodex.com/2014/04/28/the-control-group-is-out-of-control/ I. Allan Crossman calls parapsychology the control group for science. That is, in let's say a drug testing experiment, you give some people the drug and they recover. That doesn't tell you much until you give some other people a placebo drug you know doesn't work – but which they themselves believe in – and see how many of them recover. That number tells you how many people will recover whether the drug works or not. Unless people on your real drug do significantly better than people on the placebo drug, you haven't found anything. On the meta-level, you're studying some phenomenon and you get some positive findings. That doesn't tell you much until you take some other researchers who are studying a phenomenon you know doesn't exist – but which they themselves believe in – and see how many of them get positive findings. That number tells you how many studies will discover positive results whether the phenomenon is real or not. Unless studies of the real phenomenon do significantly better than studies of the placebo phenomenon, you haven't found anything. Trying to set up placebo science would be a logistical nightmare. You'd have to find a phenomenon that definitely doesn't exist, somehow convince a whole community of scientists across the world that it does, and fund them to study it for a couple of decades without them figuring it out. Luckily we have a natural experiment in terms of parapsychology – the study of psychic phenomena – which most reasonable people believe don't exist, but which a community of practicing scientists believes in and publishes papers on all the time.

Explore the intriguing critique of high modernism through James Scott's work, where wheat takes center stage as a metaphor for state control. Delve into the transition from foraging to agriculture, revealing its negative health impacts and tax-driven motivations. Understand how grain cultivation shaped early civilizations and challenged traditional historical narratives. This discussion sheds light on the complexities of state dependencies and imagines a life beyond their control.

Link: https://slatestarcodex.com/2014/08/14/beware-isolated-demands-for-rigor/ I. From Identity, Personal Identity, and the Self by John Perry: "There is something about practical things that knocks us off our philosophical high horses. Perhaps Heraclitus really thought he couldn't step in the same river twice. Perhaps he even received tenure for that contribution to philosophy. But suppose some other ancient had claimed to have as much right as Heraclitus did to an ox Heraclitus had bought, on the grounds that since the animal had changed, it wasn't the same one he had bought and so was up for grabs. Heraclitus would have quickly come up with some ersatz, watered-down version of identity of practical value for dealing with property rights, oxen, lyres, vineyards, and the like. And then he might have wondered if that watered-down vulgar sense of identity might be a considerably more valuable concept than a pure and philosophical sort of identity that nothing has. Okay, but I can think of something worse than that. Imagine Heraclitus as a cattle rustler in the Old West. Every time a rancher catches him at his nefarious business, he patiently explains to them that identity doesn't exist, and therefore the same argument against private property as made above. Flummoxed, they're unable to think of a response before he rides off into the sunset. But then when Heraclitus himself needs the concept of stable personal identity for something – maybe he wants to deposit his ill-gotten gains in the bank with certainty that the banker will give it back to him next time he shows up to withdraw it, or maybe he wants to bribe the sheriff to ignore his activities for the next while – all of a sudden Heraclitus is willing to tolerate the watered-down vulgar sense of identity like everyone else. (actually, I can think of something even worse than that, which is a TV western based on this premise, where a roving band of pre-Socratic desperadoes terrorizes Texas. The climax is no doubt when the hero strides onto Main Street, revolver in hand, saying "There's a new sheriff in town." And Parmenides gruffly responds "No, I'm pretty sure that's impossible.") At its best, philosophy is a revolutionary pursuit that dissolves our common-sense intuitions and exposes the possibility of much deeper structures behind them. One can respond by becoming a saint or madman, or by becoming a pragmatist who is willing to continue to participate in human society while also understanding its theoretical limitations. Both are respectable career paths. The problem is when someone chooses to apply philosophical rigor selectively. Heraclitus could drown in his deeper understanding of personal identity and become a holy madman, eschewing material things and taking no care for the morrow because he does not believe there is any consistent self to experience it. Or he could engage with it from afar, becoming a wise scholar who participating in earthly affairs while drawing equanimity from the realization that there is a sense in which all his accomplishments will be impermanent. But if he only applies his new theory when he wants other people's cows, then we have a problem. Philosophical rigor, usually a virtue, has been debased to an isolated demand for rigor in cases where it benefits Heraclitus.

Link: https://slatestarcodex.com/2019/09/18/too-much-dark-money-in-almonds/ Everyone always talks about how much money there is in politics. This is the wrong framing. The right framing is Ansolabehere et al's: why is there so little money in politics? But Ansolabehere focuses on elections, and the mystery is wider than that. Sure, during the 2018 election, candidates, parties, PACs, and outsiders combined spent about $5 billion – $2.5 billion on Democrats, $2 billion on Republicans, and $0.5 billion on third parties. And although that sounds like a lot of money to you or me, on the national scale, it's puny. The US almond industry earns $12 billion per year. Americans spent about 2.5x as much on almonds as on candidates last year. But also, what about lobbying? Open Secrets reports $3.5 billion in lobbying spending in 2018. Again, sounds like a lot. But when we add $3.5 billion in lobbying to the $5 billion in election spending, we only get $8.5 billion – still less than almonds. What about think tanks? Based on numbers discussed in this post, I estimate that the budget for all US think tanks, liberal and conservative combined, is probably around $500 million per year. Again, an amount of money that I wish I had. But add it to the total, and we're only at $9 billion. Still less than almonds!

Link: https://slatestarcodex.com/2015/06/06/against-tulip-subsidies/ I. Imagine a little kingdom with a quaint custom: when a man likes a woman, he offers her a tulip; if she accepts, they are married shortly thereafter. A couple who marries sans tulip is considered to be living in sin; no other form of proposal is appropriate or accepted. One day, a Dutch trader comes to the little kingdom. He explains that his homeland also has a quaint custom involving tulips: they speculate on them, bidding the price up to stratospheric levels. Why, in the Netherlands, a tulip can go for ten times more than the average worker earns in a year! The trader is pleased to find a new source of bulbs, and offers the people of the kingdom a few guilders per tulip, which they happily accept. Soon other Dutch traders show up and start a bidding war. The price of tulips goes up, and up, and up; first dozens of guilders, then hundreds. Tulip-growers make a fortune, but everyone else is less pleased. Suitors wishing to give a token of their love find themselves having to invest their entire life savings – with no guarantee that the woman will even say yes! Soon, some of the poorest people are locked out of marriage and family-raising entirely.

Link: https://slatestarcodex.com/2019/09/16/against-against-pseudoaddiction/ I. "Pseudoaddiction" is one of the standard beats every article on the opioid crisis has to hit. Pharma companies (the story goes) invented a concept called "pseudoaddiction", which looks exactly like addiction, except it means you just need to give the patient more drugs. Bizarrely gullible doctors went along with this and increased prescriptions for their addicted patients. For example, from a letter in the Wall Street Journal: Parroting Big Pharma's excuses about FDA oversight and black-box warnings only discounts how companies like Johnson & Johnson engaged in pervasive misinformation campaigns and even promoted a theory of "pseudoaddiction" to encourage doctors to prescribe even more opioids for patients who displayed signs of addiction. Or from CBS: But amid skyrocketing addiction rates and overdoses related to OxyContin, Panara claimed the company taught a sales tactic she now considers questionable, saying some patients might only appear to be addicted when in fact they're just in pain. In training, she was taught a term for this: "pseudoaddiction." "So the cure for 'pseudoaddiction,' you were trained, is more opioids?" Dokoupil asked. "A higher dose, yes," Panara said.

Thanks to everyone who offered to host a meetup. Full list of cities, times, and places is below. If you're reading this, you're invited. Please don't feel like you "won't be welcome" just because you're new to the blog, demographically different from the average reader, or hate SSC and everything it stands for. You'll be fine! Some suggestions for organizers: 1. Bring a sign that says SSC MEETUP so people can find you 2. Bring nametags and markers 3. Bring a signup sheet where people can write their names and emails if they want to hear about future meetups. 4. If people want to get to know each other better outside the meetup, you might want to mention reciprocity.io, the rationalist friend-finder/dating site. It runs off Facebook, so you have to Facebook friend the other person first. 5. Please record how many people attend; I will ask for these numbers to help with future meetup posts. 6. If you take a picture and send it to me, I'll try to post it here. I'll ask for this later, please don't email these to me until then.

Link: https://slatestarcodex.com/2019/09/11/lots-of-people-going-around-with-mild-hallucinations-all-the-time/ [Related to: Relaxed Beliefs Under Psychedelics And The Anarchic Brain, HPPD And The Specter Of Permanent Side Effects] I. Hallucinogen persisting perceptual disorder is a condition where people who take psychedelics continue hallucinating indefinitely. Estimates of prevalence range from about 4% of users (Baggott) to "nobody, the condition does not exist" (Krebs and Johansen). To explore this discrepancy, I asked about it on the 2019 SSC survey. The specific question was: Hallucinogen Persisting Perceptual Disorder is a condition marked by visual or other perceptual disturbances typical of psychedelic use that continue for weeks and months after coming off the psychedelic, in some cases permanently. Have you ever had this condition? 2,234 readers admitted to having used psychedelics. Of those, 285 (= 12.8%) stated that they had some hallucinations that persisted afterwards. 219 (9.8%) said they'd had them for a while and then they had gone away. 66 (= 3%) stated that they still had the hallucinations (one limit of the study: I don't know how long it has been since those people took the psychedelics).

Link: https://slatestarcodex.com/2019/09/10/ssc-journal-club-relaxed-beliefs-under-psychedelics-and-the-anarchic-brain/ Thanks to Sarah H. and the people at her house for help understanding this paper] The predictive coding theory argues that the brain uses Bayesian calculations to make sense of the noisy and complex world around it. It relies heavily on priors (assumptions about what the world must be like given what it already knows) to construct models of the world, sampling only enough sense-data to double-check its models and update them when they fail. This has been a fruitful way to look at topics from depression to autism to sensory deprivation. Now, in Relaxed Beliefs Under Psychedelics And The Anarchic Brain: Toward A Unified Model Of The Brain Action Of Psychedelics, Karl Friston and Robin Carhart-Harris try to use predictive coding to explain the effects of psychedelic drugs. Then they use their theory to argue that psychedelic therapy may be helpful for "most, if not all" mental illnesses. Priors are unconscious assumptions about reality that the brain uses to construct models. They can range all the way from basic truths like "solid objects don't randomly disappear", to useful rules-of-thumb like "most get-rich-quick schemes are scams", to emotional hangups like "I am a failure", to unfair stereotypes like "Italians are lazy". Without any priors, the world would fail to make sense at all, turning into an endless succession of special cases without any common lessons. But if priors become too strong, a person can become closed-minded and stubborn, refusing to admit evidence that contradicts their views. F&CH argue that psychedelics "relax" priors, giving them less power to shape experience. Part of their argument is neuropharmacologic: most psychedelics are known to work through the 5-HT2A receptor. These receptors are most common in the cortex, the default mode network, and other areas at the "top" of a brain hierarchy going from low-level sensations to high-level cognitions. The 5-HT2A receptors seem to strengthen or activate these high-level areas in some way. So:

Link: https://slatestarcodex.com/2019/09/09/partial-retraction-age-and-birth-order-effects/ On Less Wrong, Bucky tries to replicate my results on birth order and age gaps. Backing up: two years ago, I looked at SSC survey data and found that firstborn children were very overrepresented. That result was replicated a few times, both in the SSC sample and in other samples of high-opennness STEM types. Last year, I expanded those results to look at how age gaps affected birth order effects. Curiously, age gaps less than seven years did not seem to attenuate birth order, but age gaps of more than seven years attenuated it almost completely. Bucky analyzed the same data and found that I bungled one and a half of my results. Left graph in each pair is mine, right is Bucky's.