Astral Codex Ten Podcast

https://astralcodexten.substack.com/p/too-good-to-check-a-play-in-three I. Seen on Twitter: In case you find this hard to follow: ivermectin is an antiparasitic drug that looked promising against COVID in early studies. Later it started looking less promising, and investigators found that a major supporting study was fraudulent. But by this point it had gotten popular among conspiracy theorists as a suppressed coronavirus cure that They Don't Want You To Know. The media has tried to spread the word that the scientific consensus remains skeptical. In the process, they may have gone a little overboard and portrayed it as the world's deadliest toxin that will definitely kill you and it will all somehow be Donald Trump's fault. It turned into the latest culture war issue, and now there's a whole discourse on (for example) how supposedly-sober fact-checkers keep calling it "a horse dewormer" (it is used to deworm horses, but it's also FDA-approved for humans, but lots of the people using it are buying the horse version), and probably this is hypocritical in some way. Enter the article above. A doctor named Jason McElyea apparently told local broadcaster KFOR that Oklahoma hospitals are "overwhelmed" with ivermectin poisoning cases, so much so that "gunshot victims" are "left waiting". Some of the world's biggest news outlets heard the story and ran with it. The tweet mentions the Rolling Stone version, but the same story, with the same doctor's testimony, got picked up by The Guardian, the BBC, Yahoo News, etc.

https://astralcodexten.substack.com/p/new-york-meetup-this-monday When: Monday, 9/6. I'll be arriving at 5 PM but some other people might get there earlier, around 3. Where: swung.shape.shows, aka Teardrop Park in Lower Manhattan Who: Anyone who wants. Please feel free to come even if you feel awkward about it, even if you're not "the typical ACX reader", even if you're worried people won't like you, etc. Also, me! I'll be there on my meetups tour and hope to meet many of you. The New York organizers have asked me to link their LW event page and their meetup group's Google Group for organizing future events. If you're somewhere other than New York, check the spreadsheet to find the closest meetup to you.

https://astralcodexten.substack.com/p/boston-meetup-this-sunday When: Sunday, 9/5, 5 PM Where: area.bricks.tribune, aka John F Kennedy Park in Cambridge, near the picnic tables. Who: Anyone who wants. Please feel free to come even if you feel awkward about it, even if you're not "the typical ACX reader", even if you're worried people won't like you, etc. Also, me! I'll be there on my meetups tour and hope to meet many of you. Some rationalist/EA leaders are focusing on Boston right now as a promising place to community-build. They're especially trying to expand the student groups at Harvard and MIT. If you live in Boston and/or attend either of those colleges, then - whether or not you can make it Sunday - consider giving them your name through this form so they can help get you connected. If you're somewhere other than Boston, check the spreadsheet to find the closest meetup to you.

https://astralcodexten.substack.com/p/long-covid-much-more-than-you-wanted Like everyone else, I'm trying to figure out how cautious I should be around COVID. It seems like the most important concern for young vaccinated people like myself is the risk of Long COVID symptoms, so I spent a while trying to figure out what those were. My basic conclusion is that everyone else is right, that news stories on this phenomenon seem remarkably good, and that there's not much we know for sure beyond the simple summary you've probably already heard. Insofar as anything surprised me, it was how bad the worst-case scenario would be. Here are some of the basic things I found: 1. Long COVID is probably a lot of different things, some of which are boring and obvious, others of which are still kind of mysterious. First, people with severe COVID that lands them in the ICU have long-lasting symptoms in multiple organ systems. This isn't surprising, and should be considered in the context of post-ICU syndrome. Basically, if anything makes you sick enough to land in the ICU, your body is going to be pretty scarred by the illness (and maybe also by the inevitable side effects of intensive care), and this will last a long time and cause many problems. EG if you're bedridden for many weeks, your muscles waste away, and then it takes a long time for them to recover and you feel weak and fragile until you do. Or if your lungs stop working and you need mechanical ventilation, your lungs might be pretty weak for a while, and other parts of your body might not get quite the amount of oxygen they're used to and might get damaged in a way that takes a long time to recover. There's a similar problem where if you are sufficiently old and frail, any illness will take you down a level of functioning and you might not be able to get up a level again. See for example this article discussing how about 1/5 of elderly flu patients have "persistent functional decline" and may never regain their pre-flu level of functioning. Second, even in young people with milder cases, COVID can sometimes cause lung damage. If you get lung damage, you'll have at least breathing problems, and maybe other problems. Your lungs will probably heal eventually, but some kinds of lung healing cause permanent scarring; this can present as shortness of breath on exertion, or become a problem later after other lung injuries.

https://astralcodexten.substack.com/p/on-hreha-on-behavioral-economics Jason Hreha's article on The Death Of Behavioral Economics has been going around lately, after an experiment by behavioral econ guru Dan Ariely was discovered to be fraudulent. The article argues that this is the tip of the iceberg - looking back on the last few years of replication crisis, behavioral economics has been undermined almost to the point of irrelevance. The article itself mostly just urges behavioral economists to do better, which is always good advice for everyone. But as usual, it's the inflammatory title that's gone viral. I think a strong interpretation of behavioral economics as dead or debunked is unjustified. I. My medical school had final exams made of true-false questions, with an option to answer "don't know". They were scored like so: if you got it right, +1 point; wrong, -0.5 points; don't know, 0. You can easily confirm that it's always worth guessing even if you genuinely don't know the answer (+0.25 points on average instead of 0). On average people probably had to guess on ~30% of questions (don't ask; it's an Irish education system thing), so you could increase your test score 7.5% with the right strategy here. I knew all this, but it was still really hard to guess. I did it, but I had to fight my natural inclinations. And when I talked about this with friends - smart people, the sort of people who got into medical school! - none of them guessed, and no matter how much I argued with them they refused to start. The average medical student would sell their soul for 7.5% higher grades on standardized tests - but this was a step too far.

https://astralcodexten.substack.com/p/berkeley-meetup-this-saturday When: Saturday, August 28, at 1 PM Where: deflection.jump.puppy, aka the lawn where West Circle meets Free Speech Bikeway near the UC Berkeley parking lot. Who: Anyone who wants. Please feel free to come even if you feel awkward about it, even if you're not "the typical SSC reader", even if you're worried people won't like you, etc. Also, me! I'm starting my meetups tour there. I'll be announcing the meetups on the tour (about 15 of them) on this blog a day or two before they happen. Sorry for the potential spam emails if none of them are relevant to you. If you're somewhere other than Berkeley, check the spreadsheet to find the closest meetup to you.

https://astralcodexten.substack.com/p/highlights-from-the-comments-on-missing [Original article: Kids Can Recover From Missing Even A Lot Of School] I. Many commenters shared their own stories of missing lots of school and bouncing back from it. For example, Rachel E: I was unschooled until I was 15, I'm pursuing a PhD now. Catching up on the basics wasn't easy but only took a few months. There are still a bunch of random general knowledge things I don't know, but at most it's caused a moment of embarrassment in social situations (e.g., when I genuinely thought dinosaurs were mythical creatures). BUT I was motivated to catch up, which I think makes a big difference. I'd say most kids probably don't care too much about their education, so for them, missing school might matter more And ral: Hear, hear. I had serious medical problems in grade 5, needed a major surgery in grade 6, and was told I'd have to miss a year. My parents tried homeschooling, rigorously followed a bunch of curricula, and discovered I could finish *all* the assigned coursework in 2 hours/day and spend the rest of the time reading my favorite books. We were so unimpressed by the time wasted in "regular school" that we kept homeschooling another 2 years. I now have a PhD, but those were among the best days of my life. And Pepe: If you are interested in an anecdote: I did not go to high school (well, attended for two or three months) and now I have a PhD from a very good university. Not receiving any formal education between the ages of 16 and 23 does not seem to have affected my ability to do college (and later grad school) level work.

https://astralcodexten.substack.com/p/if-youre-so-smart-why-arent-you-governor Californians love long-shot bets. Actors trying to make it big in LA, tech founders chasing unicorns in San Francisco, cult leaders trying to found religions in Pasadena. In Silicon Valley, VCs turn the long-shot bet into an art: if some new startup has a 5% chance of making a billion, that's $50 million in expectation. Just a whole state full of people looking for weird opportunities. ...which makes it extra funny that the biggest opportunity of all came by a few months ago, and they all missed it. My claim is that basically anyone with the slightest amount of fame or money - any B-list actor, any second-tier tech CEO, any successful blogger or influencer, maybe me, maybe even you - could have maneuvered themselves into a position where they had a 5-10% chance of becoming Governor of California. Let's start at the beginning. Governor Gavin Newsom had a bad year. First he pissed off Republicans with his strong response to COVID. Then he pissed off the people who wanted strong responses to COVID by attending an unvaccinated unmasked dinner. Also, taxes are still high, homelessness is still high, rents are still (too damn) high, and parts of the state are literally on fire. Gavin Newsom didn't cause most of this, but he also hasn't announced any particularly inspired plans to fight it. Just a really, really bad year. (also, his ex-wife is dating Donald Trump Jr, which has to hurt) California has a long tradition of direct democracy. Citizens can circulate petitions, and if they get enough signatures, everyone has to vote on them. After several tries, Republicans finally got enough signatures on a "recall Newsom" petition to trigger an election. The way the election works is: there are two questions on the ballot. First, should Newsom be removed as governor? Second, if he is removed, who replaces him? Everyone gets to vote on both questions, so even if you want to keep Newsom you can still vote on who replaces him if he loses.

https://astralcodexten.substack.com/p/carbon-costs-quantified This post tries to quantify how much carbon is produced by various activities, lifestyle changes, and actors. can't stress enough how approximate and unreliable these numbers are. The reason I made this chart and other people didn't isn't because I'm smarter or harder-working than they are. It's because I'm less responsible, and more willing to use numbers that are kind of grounded in wild guesses, and technically shouldn't be compared to each other. My defense is they're probably mostly order-of-magnitude correct, and I believe having probably mostly order-of-magnitude correct estimates is better than having no estimates at all. Explanations below:

https://astralcodexten.substack.com/p/meetups-everywhere-2021-times-and https://docs.google.com/spreadsheets/d/1QFbM5B9KfsiwqO6DvJ4D05dQitBtZ6kYDwXZ3Hj6SEc/edit#gid=1585750313 Thanks to everyone who respond to my request for ACX outdoor meetup organizers. Volunteers have arranged meetups in 170 cities around the world, including beautiful Lusk, Wyoming (population: 1,526). You can see the full list here, and I'll also have it below in case you can't access the spreadsheet for some reason. I'll be trying to attend ~15 of the 170 meetups. Since I focused on the US last time, I'm going to focus on Europe this year (plus a few US cities on the way). My very preliminary itinerary (all dates in US month/day format) is: Berkeley: Saturday 8/28, 1 PM Boston: Sunday, 9/5, 5 PM New York: Monday, 9/6, 5 PM Washington DC: Saturday, 9/11, 5 PM Lisbon: Saturday, 9/18, 5 PM Madrid: TBD (late September?) Zurich: TBD (late September?) Vienna: TBD (late September?) Prague: TBD (early October?) Berlin: TBD (early October?) Paris: TBD (early October?) London: TBD (mid October?) Cambridge: TBD (mid October?) Oxford: TBD (mid October?) Edinburgh: TBD (mid October?) I don't want to make confident predictions about how quickly I can travel through Europe, so I'll post the rest of my schedule once I know more. If you gave me a schedule for the first five cities, I've unilaterally replaced it with what works for me, sorry. If you're trying to organize a meetup for the TBD cities, sorry I'm making your life confusing right now. Also, if COVID or something else comes up, I might have to drop some cities from my list, in which case I'll let you know and you can have a normal meetup at whatever time works for you.