Inside the ICE House

The future of mental health is being transformed, moving beyond trial-and-error treatments to science-driven precision. Breakthroughs in neuroscience, AI, and precision medicine are mapping the brain’s unique biological signatures, creating pathways for personalized care. Alto Neuroscience is at the forefront, using brain biomarkers and AI to match patients with the right therapies—fast. Founded in 2019 by Dr. Amit Etkin, the company is rewriting the rules of mental health treatment. He goes Inside the ICE house to explain how Alto is turning guesswork into guided science and offering hope where it once felt out of reach.

In August, Inside the ICE House aired five new episodes, four traditional Inside the ICE House episodes, and one episode that kicked off a new, monthly series. Episode 480: Elanco CEO Jeff Simmons on Protecting Our Pets & Advancing Animal Health Episode 481: Edwards Lifesciences CEO Bernard Zovighian on Engineering Hope & Pioneering Purpose August Markets in Focus: Inside the ICE House x Opening Bell Daily Episode 482: Houlihan Lokey CEO Scott Adelson on Markets, M&A, and Building a Global Powerhouse Episode 483: W&T Offshore CEO Tracy Krohn on Steering Oil and Gas Exploration Through Industry Transformation

Michael Reinking, Senior Market Strategist for the NYSE, recaps a busy week following Fed Chair Powell’s dovish Jackson Hole remarks, which fueled a market rally and left the door open for a September rate cut. He highlights political drama around Fed independence, the U.S. taking stakes in Intel and MP Materials, and Nvidia’s strong earnings that lifted the AI sector. Reinking notes the S&P 500 hitting record highs with solid August gains, while warning that September brings labor data, inflation reports, and Fed policy decisions into sharper focus.

Artificial intelligence is reshaping industries by unlocking insights hidden within massive amounts of unstructured data. With powerful tools like vector databases and enterprise platforms, AI is driving breakthroughs across healthcare, finance, and entertainment. Pinecone founder Edo Liberty and HumanX founder Stefan Weitz have been at the forefront of this transformation. They join the Inside the ICE House podcast for breakfast on the balcony above the NYSE trading floor to share their journeys, explore the problems they’re solving, and discuss how AI is accelerating innovation and redefining the future.

The offshore oil and gas industry fuels progress by unlocking hidden energy reserves deep beneath the ocean’s surface. With advanced technology, it thrives in some of the world’s harshest environments to power industries, transportation, and daily life. W&T Offshore has been a leader in this space for more than four decades. Tracy Krohn, who founded the company in 1983 and still leads it to this day, goes Inside the ICE House to discuss W&T Offshore’s journey, its focus on efficiency, sustainability, and safety, and the future of offshore energy.

Eric Criscuolo, Market Strategist for the NYSE, breaks down a week dominated by anticipation for Fed Chair Powell’s Jackson Hole speech. He highlights muted market action early in the week, followed by a sharp rotation out of mega-cap tech, AI, and crypto-related equities into lagging sectors. He notes that FOMC minutes showed broad support for holding rates steady, though market odds of a September cut remain elevated after controversial jobs data. Retail earnings, including Walmart, underscored ongoing consumer pressures but failed to shift the broader narrative. Looking ahead, Powell’s speech, July PCE inflation data, and Nvidia’s earnings will be the key catalysts driving markets into September.

Sal Gilbertie, CEO of Teucrium Trading, joins Bilal Little, Director of Exchange Traded Products at the NYSE.

The M&A landscape has rebounded in 2025, driven by stable interest rates, improved market conditions, and rising CEO confidence. Strategic buyers are fueling the surge, targeting deals that boost growth, expand capabilities, and enhance competitive positioning. Houlihan Lokey has emerged as the global leader in M&A volume. Just over a year into his role, CEO Scott Adelson is proving that steady leadership and deep institutional expertise drive results. He goes Inside the ICE House to detail how, under his guidance, the firm is expanding globally, strengthening industry verticals, and sharpening its focus on long-term value creation.

Michael Reinking, Senior Market Strategist for the NYSE, details the latest trends and developments in global markets. He discusses markets rebounding ahead of key inflation data and a 90-day U.S.-China tariff extension, with Nvidia and AMD agreeing to unprecedented export fees. He details how a mixed CPI report lifted equities before hotter PPI data—driven by services inflation—halted the rally. He notes that mega-cap tech strength is masking broader market weakness, while a September Fed rate cut still appears likely. He points to Powell’s upcoming Jackson Hole speech, retail earnings, and geopolitical events as the next key catalysts.

In a new collaboration between the Inside the ICE House Podcast and Opening Bell Daily, Phil Rosen joins to break down the hottest market headlines and the forces moving Wall Street. He unpacks the growing buzz around potential Fed rate cuts, exploring how shifts in monetary policy could ripple across sectors and reshape investor sentiment. Phil also spotlights the surge in AI spending among the tech giants powering the Magnificent 7, explaining why these investments could define the next chapter of market growth.