OncoPharm

Providing some clinical pearls learned in the last week regarding patient education for ruxolitinib & alectinib. Then (11:50) we recap follow-up publications from Keynote-24 & the BRIGHT studies, before finishing up the week's journal scan with a discussion of the optimal dose of nivolumab + ipilimumab in melanoma and who may NOT benefit from palbociclib.

Discover the latest breakthroughs in renal cell carcinoma treatments stemming from the ASCO Genitourinary symposium. Learn how the combination of pembrolizumab and axitinib is reshaping survival rates and responses, despite some treatment-related toxicities. Delve into darolutamide, a new androgen antagonist, and its anticipated FDA approval. The conversation also highlights important drug interactions with statins, particularly for older men with prostate cancer, inviting thoughts on future oncology pharmacy discussions.

The Landmarks in Oncology Pharmacy series returns to discuss the International Randomized Study of Interferon vs. STI571 (imatinib) aka IRIS.

CBD use is becoming more widespread in society, including in cancer patients. Potential, and significant, drug interaction concerns should be considered.

Mucositis & stomatitis are basically interchangeable terms for one of the hallmark chemotherapy toxicities. We discuss its pathophysiology, prevalent, and prevention/treatment.

Olaratumab received accelerated approval in 2016 under the condition a phase III study would confirm its benefit. It didn't. We explore some possible explanations why a seemingly promising drug for a tough disease hasn't panned out...

It's always enlightening to talk to a cancer survivor and is an essential part of the patient care process. This conversation touches on chemo-induced toxicities (e.g. ifosfamide neurotoxicity), supportive care advances (olanzapine!), and the anxiety of survivors live with while living scan-to-scan. Brought to you by the Bill Gatton College of Pharmacy.

We finish discussing the 2018 FDA-approvals (calaspargase, ravulizumab, tazgraxofusp).

Discover the latest insights on the modified FOLFIRINOX regimen for pancreatic cancer. Delve into the findings of the PRODIGE-24 study and its implications for adjuvant therapies. The conversation navigates the complexities of treatment, including potential benefits and complications like neuropathy. Engaging discussions highlight the evolution of cancer treatments and encourage audience participation in oncology topics.

Keeping it light this Holiday Season with a discussion of the portrayal of pharmacists, notably Mr. Gower from It's a Wonderful Life, in pop culture. Regular Pods return in 2019.