OncoPharm
John Bossaer
OncoPharm is a podcast dedicated to all things oncology pharmacy. Most episodes cover updates and recent publications concerning the use of medications in caring for patients with cancer. Periodically, episodes drop devoted to Landmark Clinical Trials in oncology and Fundamentals of Oncology Pharmacy.
Episodes
Mentioned books
May 23, 2019 • 14min
AC - - > T (q 3 week)
The Landmarks in #OncoPharm continues down its breast cancer-centric track with the landmark CALGB 9344 trial that established the role of paclitaxel in the adjuvant setting --> https://ascopubs.org/doi/pdf/10.1200/JCO.2003.02.063
May 23, 2019 • 15min
AC (NSABP B-15)
The Landmarks in #OncoPharm series returns with a discussion of NSABP B-15, which established AC as a standard adjuvant chemo regimen for breast cancer --> (https://ascopubs.org/doi/abs/10.1200/JCO.1990.8.9.1483)
May 16, 2019 • 13min
May Approvals, More Questions
Running through updated FDA approvals from this month (ivosidenib, T-DM1, ramucirumab, avelumab/axitinib, & venetoclax/obinutuzumab) and how these approvals raise more questions.
May 9, 2019 • 19min
Imatinib
The Foundations of OncoPharm returns with imatinib, the 1st TKI. Discussion includes its history (and how imatinib's Phase I study almost didn't happen), uses, and toxicity.
May 2, 2019 • 14min
Updates: bb2121 (myeloma CAR-T) and 1st line use of ivosidenib in AML
Discussion of 2 important malignant hematology updates: the NEJM publication of the 1st published results of CAR-T therapy in multiple myeloma and the FDA-approval of ivosidenib in frail AML patients (with IDH1 mutations).
Apr 24, 2019 • 12min
Lenvatinib vs. Sorafenib (HCC)
Reviewing the REFLECT (https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(18)30207-1/fulltext) study and its take-home points on selecting an agent for advanced HCC.
Apr 18, 2019 • 22min
Erdafitinib
Summary of erdafitinib's FDA-approval including dosing, MOA, toxicity, and (wait 'til the end) prevalence of FGFR mutations. Ifos. Eye-Phos.
Apr 11, 2019 • 14min
HOPA '19 Reflections
Reflections offered from HOPA's 2019 annual conference on cabozantinib, regorafenib, low-dose azacitidine, SC granisetron (this is a thing), clinical trial hope, and opportunities for students in HOPA
Apr 2, 2019 • 12min
OncoPharm M & M - Drug Interaction
Debut of a new feature: OncoPharm M & M, where we'll discuss notable case reports of #oncopharm misadventures....how they happened...and how we can prevent them in the future. Our first installment in this series discusses a drug interaction between idelalisib & diazepam (Case Report Link: https://doi.org/10.1177%2F1078155216653705).
17 snips
Mar 28, 2019 • 18min
Etoposide
Discover the fascinating origins of etoposide, derived from the mayapple plant! Dive into its role as a topoisomerase II inhibitor and how it revolutionized cancer treatment since FDA approval in 1983. There's a deep dive into dosage regimens and the balance between efficacy and toxicities. Plus, enjoy some entertainingly unnecessary historical tidbits about podophyllotoxins. A blend of science and captivating stories awaits!
