Big Picture Medicine

Do we want a Silicon Valley for healthcare? Professor Tony Young is the National Clinical Director for Innovation at NHS England, co-founder of the UK’s £500M MedTech Campus, founder of the NHS Clinical Entrepreneur Programme and a consultant urological surgeon. Tony was awarded an OBE for services to clinical leadership in the 2019 New Year Honours List. Tony has recently opened applications for the NHS Clinical Entrepreneur programme. Apply here: https://www.england.nhs.uk/aac/what-we-do/how-can-the-aac-help-me/clinical-entrepreneur-training-programme/ This is a really fun conversation — we cover Tony’s story, how and if the UK can make a Silicon Valley for healthcare and how to be charismatic. You can find me on Twitter @MustafaSultan and subscribe to my newsletter on www.musty.io

A paper published in the Lancet Digital Health found that less than 1% of clinical AI studies reviewed were of sufficient quality to have confidence in their results. This is a huge problem. Dr Xiao Liu and Professor Alastair Denniston are part of the team who published that study — and to tackle this this problem — they have today published the first international standards for the reporting of clinical AI trials. These are called SPIRIT-AI and CONSORT-AI and have today been published in Nature Medicine, the Lancet Digital Health and the BMJ. The goal of these guidelines is to improve the quality of clinical AI studies and increase their transparency. We talk about the general quality problem in clinical AI research, we talk about their guidelines and some of the recommendations within them — and also about what the future of clinical AI validation looks like. Papers Nature Medicine CONSORT-AI: https://doi.org/10.1038/s41591-020-1034-x SPIRIT-AI: https://doi.org/10.1038/s41591-020-1037-7 The Lancet Digital Health CONSORT-AI: http://www.thelancet.com/journals/landig/article/PIIS2589-7500(20)30218-1/fulltext SPIRIT-AI: http://www.thelancet.com/journals/landig/article/PIIS2589-7500(20)30219-3/fulltext BMJ CONSORT-AI: https://www.bmj.com/content/370/bmj.m3164 SPIRIT-AI: https://www.bmj.com/content/370/bmj.m3210

What's it like running a company which has raised $90M? Dr Ben Maruthappu is the co-founder and CEO of Cera Care — a technology enabled home care company. I could speak about Ben’s achievements and accolades for hours, but to give you a whistle stop tour — he is a successful doctorpreneur, has published some very influential papers, and has worked in health policy — perhaps most notably — he was an advisor to Simon Stevens (CEO of NHS England). Ben was awarded an MBE for services to Health and Care technology in the 2020 Queen’s New Year Honours List. We talk about how Ben got to where he is along with what he learned at every step. We also dive quite deep into what it’s actually like to be CEO of such a large company. This is one of my favourite interviews — because Ben is incredibly candid and gives lots of useful advice. I hope you enjoy. Find Ben LinkedIn: https://www.linkedin.com/in/mahibenmaruthappu/ Cera Care: https://ceracare.co.uk You can find me on Twitter @MustafaSultan and subscribe to my newsletter on www.musty.io

Do you need to be a silverback gorilla to be a good leader? 🦍  Professor David Lomas is the Vice Provost (Health) at University College London and Head of UCL Medical School. He is also a hugely accomplished academic with his most notable work focusing on alpha-1 antitrypsin deficiency. He has a h-index of 95. We talk about lots of things — like the future of medical education,  what makes a good leader and how to make good decisions. Find Prof David Lomas UCL: https://iris.ucl.ac.uk/iris/browse/profile?upi=DALOM96 You can find me on Twitter @MustafaSultan and subscribe to my newsletter on www.musty.io

Do you want the granular step-by-step on how to launch your own MedTech startup? Dr Krishan Ramdoo was an ENT Surgeon before co-founding TympaHealth; the world’s first all in one hearing health assessment system. It’s essentially a digital otoscope (a scope that helps visualise inside the ear). Traditionally this was an analogue device, so no one else could see what you saw when you examined the ear — but with the Tympahealth system, you can see what the scope is looking at on your phone screen and then save that video to the patient’s records. Unlike other similar devices, you can also use it to remove ear wax. It was the winner of the global UX design award and it’s seriously beautiful. You can go to tympahealth.com to see what it looks like. TympaHealth have been very active in the battle against COVID, and the system has been trialled in the UCLH Trust in the country’s first tele-otology service. This conversation is basically a deep dive into how Krishan has achieved what he has with TympaHealth. How he went from an idea in his head to his device being used by 1000s of patients as well as by Boots Hearing Care. He’s a masterful storyteller — I hope you enjoy. Find Krishan TympaHealth: https://www.tympahealth.com Krishan: https://www.linkedin.com/in/krishan-ramdoo-10086979/ You can find me on Twitter @MustafaSultan and subscribe to my newsletter on www.musty.io

What does the future radiologist look like? What does everyone get wrong when regulating their AI startup? Dr Hugh Harvey trained as a consultant radiologist and is now the managing director of Hardian Health; a health-tech consultancy firm. He has had an incredible career, sitting at the interface of Medicine and technology. He was headhunted by Dr Eric Topol to co-chair the Topol Review, he sits on the board of Nature Digital Medicine and was formerly head of regulatory affairs at Babylon Health. He has twice been awarded science writer of the year by the Institute of Cancer Research in London and you can find him on Twitter @DrHughHarvey, where he candidly shares his thoughts on medical AI and clinical validation amongst other things. Seriously, I recommend following him. Essentially he understands the worlds of AI, Medicine, business as well as regulation and validation. This is a really interesting conversation — hope you enjoy. Find Hugh Twitter: https://twitter.com/DrHughHarvey Hardian Health: https://hardianhealth.com You can find me on Twitter @MustafaSultan and subscribe to my newsletter on www.musty.io

You're an average medical student with no connections — how do you get published!? *Congratulations to Azeem who was awarded the British Empire Medal for services to Medical Education during COVID-19* Dr Azeem Alam completed his surgical AFP training in London and is the co-founder of BiteMedicine — the medical knowledge platform. He shares his step-by-step framework on getting published without a leg up. Find Azeem BiteMedicine: https://www.bitemedicine.com LinkedIn: https://www.linkedin.com/in/azeemalam/ Music: https://www.youtube.com/watch?v=9Ngjub5Ntqk You can find me on Twitter @MustafaSultan and subscribe to my newsletter on www.musty.io

How can a surgeon assist in an operation across the world — using their web browser? Dr Nadine Hachach-Haram BEM is a plastic surgeon and CEO of Proximie — an augmented reality platform for virtual surgical collaboration. Rather than telemedicine it’s about telepresence. It means that a surgeon in the UK could open up their web browser, and see what another surgeon across the world is doing in real time and collaborate. Proximie has had incredible impact: it’s helped people in need across the world access surgical care, it’s been used by NHS surgeons who are self-isolating due to coronavirus and it’s also being used by the RAF. Dr Nadine received the British Empire Medal in the 2018 Queen’s Birthday Honours for her innovation in surgery This is a really cool interview: we start off by talking about augmented reality in surgery before moving onto Dr Nadine’s transition from a plastic surgeon to a CEO, some business strategy and finally her advice for fledgling doctorpreneurs. Find Dr Nadine: Twitter: https://twitter.com/DrNadz Proximie: https://www.proximie.com You can find me on Twitter @MustafaSultan and subscribe to my newsletter on www.musty.io

How could better understanding your internal state improve your mental health? Dr David Plans is a lecturer in Organisational Neuroscience and CEO of BioBeats; a company on a mission to free people from mental suffering. He’s completing his second PhD in Experimental Psychology at the University of Oxford and has raised over $6M to turn his academic research into a bustling company. This is a really interesting conversation in which I’m completely out of my depth. We start by discussing David’s story and his view of hustle culture and how enhancing peoples’ interoception (which is loosely defined as understanding the internal state of your body) could improve their mental health. Thank you to Elise Plans for the music you hear. Find Dr David Plans BioBeats: https://biobeats.com David's Personal Website: http://www.davidplans.com You can find me on Twitter @MustafaSultan and subscribe to my newsletter on www.musty.io

Professor Shafi Ahmed is the world’s most watched surgeon.  He has live-streamed operations using Google Glass, the Snapchat Spectacles — and even virtual reality technology. He’s really at the cutting edge of surgical innovation so it was a real privilege to speak to him. He is the co-founder of Medical Realities; a company which specialises in surgical VR and AR tech. He has spoken at Wired Health, TEDx — he leads charity work in his native Bangladesh, he’s setting up a hospital of the future in Bolivia. He has consulted for Google, PwC, Roche — he has advised the NHS on the Long Term Plan and was awarded the Future NHS Award by members of Parliament in 2018. Find Professor Shafi Ahmed Website: https://surgeon.ai Twitter: https://twitter.com/ShafiAhmed5 Wired Health Talk: https://www.youtube.com/watch?v=vftA-_c1hYc You can find me on Twitter @MustafaSultan and subscribe to my newsletter on www.musty.io