Possible
Reid Hoffman
What if, in the future, everything breaks humanity's way? Possible is an award-winning, weekly podcast that sketches out the brightest version of the future—and what it will take to get there. Hosts Reid Hoffman and Aria Finger explore what’s possible with forward-thinking leaders, deep thinkers, and ambitious builders across many fields, such as technology, art, education and healthcare. These conversations center on the ways technology—and, in particular, AI—is shaping the future. In episodes, AI tools such as OpenAI’s GPT-4 and Inflection’s Pi are at work, offering informational asides, prompting guests, or demoing what they can do. Lastly, between guest episodes, Aria interviews her co-host Reid on his latest takes on what’s possible if we use technology—and our collective effort—effectively.
Episodes
Mentioned books
12 snips
Dec 24, 2025 • 59min
Stephen Colbert on connection, discovery, and human nature
Join comedian and political satirist Stephen Colbert as he explores the transformative nature of live performance and its role in building genuine connections. He delves into the complexities of creativity in the age of AI, questioning whether machines can replicate the richness of human emotion. Colbert discusses the insights from J.R.R. Tolkien that shape his worldview and reflects on the vital imperfections of human interaction. He also shares hopes for the future, from advancements in medicine to deeper explorations of space.
28 snips
Dec 17, 2025 • 32min
The power of AI, from curing cancer to ballot boxes
Siddhartha Mukherjee, a Pulitzer Prize-winning oncologist and the mind behind Manas AI, dives deep into the transformative role of AI in medicine. He highlights breakthroughs in cancer immunotherapy, including engineered T-cells that tackle previously unsolvable cases. The conversation extends to AI's potential in drug discovery, creating a 'molecular oracle' for new treatments. They also explore Silicon Valley's evolving culture, advocating for technology that prioritizes humanity and truth, especially as AI influences public discourse and political opinion.
62 snips
Dec 10, 2025 • 18min
The AI energy war is here
Explore why compute is now considered the new oil fueling the cognitive industrial revolution. Discover how data centers are driving wage growth for blue-collar workers and reshaping local economies. Address common myths about their energy costs and learn how China's aggressive energy expansion poses a competitive threat. Hear calls for a comprehensive U.S. energy strategy that includes nuclear, solar, and wind to secure jobs and intellectual property. Understand the importance of keeping AI infrastructure on American soil for national security and prosperity.
114 snips
Dec 3, 2025 • 45min
R.I.P. Computer Keyboard (1964 – 2025)
Tanay Kothari, Founder and CEO of Wispr Flow, shares insights on a future where voice replaces keyboards as the primary interface. As a child, Tanay built one of the first voice assistants, paving the way for his innovative AI product used by many Fortune 500 companies today. He discusses how voice enhances accessibility, emotional connection, and user engagement while showcasing a thrilling live demo comparing voice typing to traditional typing. Tanay envisions a world where technology encourages human presence and interaction, transforming how we communicate.
51 snips
Nov 26, 2025 • 16min
AI’s Influence On The Church, Cybersecurity, and Disney
Listen in as Reid and Aria explore Pope Leo XIV's call for moral integrity in AI development. The discussion shifts to the Church's role in guiding tech ethics amidst rising cyber threats from agentic AI. The duo delves into the implications of Disney potentially opening its IP to fan creators, sparking dialogues on storytelling and audience engagement. They question how AI impacts cultural and spiritual dimensions, emphasizing the need to prioritize human dignity in a rapidly evolving technological landscape.
115 snips
Nov 19, 2025 • 1h 8min
Our AI blindspot: incentives over intentions
Join Aza Raskin, a technologist and designer renowned for his work on user engagement, as he critiques the intersection of AI and social media. He discusses how tech can exploit human behavior and emphasizes that incentives often overshadow intentions. Raskin warns about the psychological depth AI will target and argues for treating tech platforms as fiduciaries. With insights on engagement risks for children and the need for regulation, he offers a hopeful vision for aligned collective intelligence and actionable steps for a better future.
49 snips
Nov 12, 2025 • 35min
How we regulate AI could decide the next century
Hosts dive into the collision of AI with real-world regulations, highlighting new laws in states like Utah and California. They discuss how OpenAI self-limits advice in sensitive areas to manage liability. The conversation turns global, exploring China’s push for an international AI governance body and the U.S. risks involved. A fascinating study reveals that AI performs better with rude prompts, sparking debate on user behavior and training ethics. Ultimately, they question what kind of intelligence we truly want to foster.
49 snips
Nov 5, 2025 • 30min
Reid riffs on NVIDIA's chips, China’s AI ambitions, and the push to pause AI
This week’s discussion dives into the explosive growth of NVIDIA and the U.S.-China chip rivalry. Insights reveal that AI's future hinges on how we deploy technology, reshaping fields like medicine. Reid argues that doctors who embrace AI tools will outperform those who don’t. He also addresses recent calls to pause AI development, emphasizing the importance of advancing safety alongside progress. The episode wraps up with thoughts on the necessity of continuous learning for medical professionals in an AI-enhanced landscape.
39 snips
Oct 29, 2025 • 1h 2min
Steve Kerr and Kris Brown on Leadership, Purpose, and Innovation in Sport and Society
Steve Kerr, the head coach of the Golden State Warriors and advocate against gun violence, joins Kris Brown, president of the Brady organization, to discuss advocacy and change. They share personal stories tying them to their causes and explore innovative approaches to gun violence prevention, like safe storage and smart firearm tech. Kerr reflects on leadership lessons from coaching legends and the evolving role of analytics in basketball, while emphasizing the responsibility of athletes to speak out on pressing social issues.
69 snips
Oct 22, 2025 • 27min
Aza Raskin on interspecies communication, empathy, and AI’s next frontier
Aza Raskin, co-founder and CEO of the Earth Species Project, dives into the fascinating realm of animal communication and empathy. He explains how AI can decode the languages of species like dolphins and crows, revealing their complex social structures and innovative behaviors. Aza shares insights on communal rearing practices in crows and the groundbreaking implications of recognizing animal intelligence. This enlightening conversation redefines our perspective on the natural world and challenges us to become better listeners.
