Possible
Reid Hoffman
What if, in the future, everything breaks humanity's way? Possible is an award-winning, weekly podcast that sketches out the brightest version of the future—and what it will take to get there. Hosts Reid Hoffman and Aria Finger explore what’s possible with forward-thinking leaders, deep thinkers, and ambitious builders across many fields, such as technology, art, education and healthcare. These conversations center on the ways technology—and, in particular, AI—is shaping the future. In episodes, AI tools such as OpenAI’s GPT-4 and Inflection’s Pi are at work, offering informational asides, prompting guests, or demoing what they can do. Lastly, between guest episodes, Aria interviews her co-host Reid on his latest takes on what’s possible if we use technology—and our collective effort—effectively.
Episodes
Mentioned books
30 snips
Nov 12, 2025 • 35min
How we regulate AI could decide the next century
Hosts dive into the collision of AI with real-world regulations, highlighting new laws in states like Utah and California. They discuss how OpenAI self-limits advice in sensitive areas to manage liability. The conversation turns global, exploring China’s push for an international AI governance body and the U.S. risks involved. A fascinating study reveals that AI performs better with rude prompts, sparking debate on user behavior and training ethics. Ultimately, they question what kind of intelligence we truly want to foster.
49 snips
Nov 5, 2025 • 30min
Reid riffs on NVIDIA's chips, China’s AI ambitions, and the push to pause AI
This week’s discussion dives into the explosive growth of NVIDIA and the U.S.-China chip rivalry. Insights reveal that AI's future hinges on how we deploy technology, reshaping fields like medicine. Reid argues that doctors who embrace AI tools will outperform those who don’t. He also addresses recent calls to pause AI development, emphasizing the importance of advancing safety alongside progress. The episode wraps up with thoughts on the necessity of continuous learning for medical professionals in an AI-enhanced landscape.
39 snips
Oct 29, 2025 • 1h 2min
Steve Kerr and Kris Brown on Leadership, Purpose, and Innovation in Sport and Society
Steve Kerr, the head coach of the Golden State Warriors and advocate against gun violence, joins Kris Brown, president of the Brady organization, to discuss advocacy and change. They share personal stories tying them to their causes and explore innovative approaches to gun violence prevention, like safe storage and smart firearm tech. Kerr reflects on leadership lessons from coaching legends and the evolving role of analytics in basketball, while emphasizing the responsibility of athletes to speak out on pressing social issues.
60 snips
Oct 22, 2025 • 27min
Aza Raskin on interspecies communication, empathy, and AI’s next frontier
Aza Raskin, co-founder and CEO of the Earth Species Project, dives into the fascinating realm of animal communication and empathy. He explains how AI can decode the languages of species like dolphins and crows, revealing their complex social structures and innovative behaviors. Aza shares insights on communal rearing practices in crows and the groundbreaking implications of recognizing animal intelligence. This enlightening conversation redefines our perspective on the natural world and challenges us to become better listeners.
60 snips
Oct 15, 2025 • 37min
Reid riffs on fostering trust with founders, in boardrooms, and in AI
Reid Hoffman, co-founder of LinkedIn and prominent investor, offers insightful perspectives on trust-building in business. He emphasizes that trust is a skill requiring transparency and direct conflict resolution. Reid shares his hands-on experiences with Airbnb and OpenAI, highlighting the importance of showing up during crises to earn trust. He discusses how founders should carefully select board members and foster public trust in AI through transparency and accountability, advocating for collaborative governance that upholds democratic values.
40 snips
Oct 8, 2025 • 1h 8min
David Fajgenbaum on drug repurposing, AI, and saving his own life
David Fajgenbaum, a physician-scientist and rare-disease advocate, shares his inspiring journey from receiving last rites to founding EveryCure. He discusses life-saving drug repurposing, including a treatment he found for his own Castleman disease. Delving into the integration of AI in healthcare, David explores how it can accelerate diagnoses and treatments while addressing ethical concerns. With tales of resilience and innovation, he highlights the potential for faster medical discoveries and a future where existing drugs can treat a multitude of conditions.
136 snips
Oct 1, 2025 • 35min
Reid riffs on Trump’s $100K visa fee, 3-day work weeks, and AI trust issues
Join Reid Hoffman, co-founder of LinkedIn and tech innovator, as he explores critical issues with immigration and AI. He discusses the implications of proposed $100K H-1B visa fees and advocates for startup exemptions to foster innovation. The conversation shifts to developers' skepticism about AI in coding, while medical AI shows promise with increased accuracy in predictions. Reid reflects on the challenges of adopting a three-day work week and underscores the importance of rebuilding trust in institutions through impactful initiatives.
122 snips
Sep 24, 2025 • 44min
Lisa Su on semiconductors, compute, and big bets
Lisa Su, Chair and CEO of AMD, shares her journey from a childhood fascination with hardware to leading a major tech turnaround. She discusses the pivotal role of semiconductors in fueling innovation and how AI could revolutionize healthcare. Lisa also explores AMD’s strategic vision versus NVIDIA, the implications of geopolitics on chip manufacturing, and the importance of long-term planning in a fast-paced industry. With insights on talent and risk-taking, she offers an optimistic outlook on the future of technology and its potential to better lives.
73 snips
Sep 17, 2025 • 21min
Reid Riffs on AI translations, Apple Intelligence, and OpenAI’s Critterz
Reid and Aria dive into Apple's latest AirPods Pro 3, featuring exciting live translation capabilities. They discuss how AI is transforming filmmaking with OpenAI's animated movie 'Critterz.' The conversation also touches on the balance between technology and creativity, emphasizing the importance of human values in AI development. They reflect on how advancements in AI can amplify human experience and creativity while cautioning against losing essential human qualities. It's a fascinating exploration of technology's impact on communication and artistic expression.
90 snips
Sep 10, 2025 • 57min
Stephen Colbert on connection, discovery and human nature
Stephen Colbert, a renowned comedian and political commentator, brings his unique insights on connection and creativity. He riffs on the importance of live performance and how it fosters genuine human connections. The conversation delves into the complexities of AI in art, questioning if it can surpass human creativity. Colbert also reflects on J.R.R. Tolkien's lessons and how humor serves as a 'third space' for empathy. They explore parasocial relationships and the impact of technology on emotional depth, emphasizing the essence of being human in a digital age.
