GeriPal - A Geriatrics and Palliative Medicine Podcast

Harm reduction, as so clearly described by our guest Monica Gandhi on this podcast, began as a public health approach that guided management of HIV. Harm reduction represented an alternative to an abstinence-only approach, which clearly did not work. In the harm reduction model, you acknowledge that people will take some risks, and that the goal is to decrease risk, not eliminate it. And yet, here we are with a fear-not-facts approach to the COVID-19 pandemic. Some are advocating for the use of masks in schools, hospitals, and nursing homes in perpetuity. As in, forever. Sounds eerily like an abstinence-only approach, right? Science would dictate that now that we have vaccines, which Monica describes as "the solution," we don't need to engage in masking (with a few exceptions). Monica Gandhi, an infectious disease doctor at UCSF, has advocated strongly for a fact-based approach to school opening, early masking and now dropping masking, and global access to vaccinations (and temporarily dropping vaccine patents), among other things. You can and should follow her: @MonicaGandhi9 And from Ashwin Kotwal, geriatrician and palliative care doc-researcher, we hear about experiences caring for patients who are afraid to return to normal after a year of masking and forced isolation, despite the toll these experiences have taken on them (documented in his recent paper in the Journal of the American Geriatrics Society). It's time to get back where we once belonged. (song choice hint) -@AlexSmithMD

In your clinical experience, you may have cared for patients receiving palliative chemotherapy and wondered, hmmm, why is that called "palliative" chemotherapy? We've written about this issue previously here at GeriPal ("a term that should be laid to rest") as has Pallimed ("an oxymoron"). Well, now we have "palliative" inotropes for people with heart failure. And we have to ask, is this a fitting term? And the answer is...complex...more so than you might think. Recall that in one of our earliest podcasts, we talked with Nate Goldstein who memorably proclaimed "the best palliative care for heart failure is treatment for heart failure." To unpack the issue of palliative inotropes, we welcome back Haider Warraich, a cardiologist with a strong interest in palliative care. We are joined again by Anne Rohlfing, palliative care fellow at UCSF who spent last year as a hospitalist on the heart failure service. Please tune in to hear more about the role of palliative care in inotrope therapy, inotropes in hospice, Haider's study on palliative needs of patients with heart failure, and a bit about Left Ventricular Assist Devices (including a shout out to Dan Matlock's decision aids) and Haider's Journal of Palliative Medicine paper on top 10 tips for palliative care clinicians on caring for patients with LVADs. -@AlexSmithMD

What is a care manager? In this week's podcast we talk with Chanee Fabius, who after a personal experience caring for a family member with dementia, became a care manager. Chanee explains in clear terms what a care manager is, what training is required, and what training is required. In essence, a care manager is a "glue person" who hold things together. After observing major race/ethnic disparities in caregiving, Chanee was inspired to obtain a doctoral degree in gerontology, and her research is now directed toward reducing disparities in caregiving, particularly for patients with dementia. See for example, her recent paper in the Gerontologist describing Black and White differences in caregiving. We are also joined by Halima Amjad, a geriatrician-researcher, who, like Halima, is at Hopkins. Halima is very interested in improving care for people with dementia. As she notes, when we talk about outcomes for older adults, we often talk about the characteristics of the patient as predictors, but rarely do we consider how caregiver factors might influence important outcomes for older adults. In a paper published in JAGS, Halima found that caregiver factors predict hospitalization. For example, caregivers who are new to the caregiving role are more likely to care for someone who is subsequently hospitalized than someone who has been caregiving for longer. We talk about all things caregivers, including research issues around the need to assess the needs of caregivers, health policy issues such as how to provide more support for caregivers, and clinical issues, such as the fact that the identity and contact information for caregivers are not routinely captured in the EHR. -@AlexSmithMD

A September 2000 New York Times article titled, "Sometimes Saving the Heart Can Mean Losing the Memory" describes a relatively newly described phenomena of difficulty with memory and other cognitive tasks six months after cardiac bypass graft surgery, or CABG. The syndrome was termed "pump head." A doctor is quoted in the article as stating that older patients he might have previously considered CABG for he would try to manage medically, with a stent. Data on the impact of CABG on cognitive function over the subsequent 20 years has been mixed. The problem with these prior studies is they enrolled patients at the time of the CABG. They didn't have a sense of what the cognitive trajectory was before the procedure. In this context, enter Liz Whitlock's study published this week in JAMA comparing cognitive trajectories before and after CABG versus stenting procedures. Liz finds no difference in the decline in memory before or after CABG vs PCI - in other words - their memory continued to decline at the same rate after each procedure as before. Furthermore, a newer procedure intended to spare patients the risks of bypass, called "off pump" CABG, was found in this study to be associated with greater memory decline than on pump CABG. Pump head, it seems, is not a thing. Those who get CABGs likely also had vascular disease in the brian that was leading to a steady cognitive decline before the procedure. To contextualize these findings for practicing geriatricians and other PCPs, we are joined by Mike Rich, one of the early movers and shakers in the field of geriatric cardiology. We are doing these cardiac procedures on ever older and older patients. What should we be concerned about? How should we counsel our patients? Listen to find out! -@AlexSmithMD

Frailty. What the heck is it? Why does it matter? How do we recognize it and if we do recognize it, is there anything we can do about it? On today's podcast we talk to Linda Fried, Dean of Columbia University's Mailman School of Public Health and world renown frailty researcher about all things frailty. We talk to Dr. Fried about how she first got interested in frailty, how we define it including the difference between phenotypic frailty and a "deficit accumulation model' frailty index", and how we should think about assessing frailty and managing it. We also talk with Dr. Fried about how she thinks about resiliency and the analogy put forth by George A. Kuchel in a wonderful article published in the Journal of American Geriatrics Society (JAGS) that uses the Golden Gate Bridge to explain different definitions of frailty.

Though origins of the term "moral injury" can be traced back to religious bioethics, most modern usage comes from a recognition of a syndrome of guilt, shame, and sense of betrayal experienced by soldiers returning from war. One feels like they crossed a line with respect to their moral beliefs. The spectrum of acts that can lead to moral injury is broad, ranging from killing of an enemy combatant who is shooting at the soldier (seemingly acceptable under wartime ethics), to killing of civilians or children (unacceptable). One need to witness the killing - dropping bombs or napalm can result in moral injury as well - nor need it be killing; harassment, hazing, and assault can result in moral injury, as can bearing witness to an event. While there is often overlap between moral injury and post-traumatic stress disorder (PTSD), they are not synonymous. Today we talk with Shira Maguen, psychologist and Professor at UCSF and the San Francisco VA. One of the many fascinating parts of our discussion is when we talk about the moral injury faced by healthcare workers during COVID. I encourage you to listen to the last podcast to hear what moral injury can sound like - being asked to care for patients under far less than ideal circumstances, care that is the best under the circumstances but is not standard of care, wondering if as a result patients may have been harmed or died. One common feature of moral injury in combat is a feeling of betrayal by superior officers who order soldiers to act in a way that contravenes their self-conception of right and wrong. One might say we in healthcare experienced a similar betrayal of leadership that flouted the science of mask wearing, stated that doctors were billing for COVID excessively to turn a profit, and touted unproven and potentially harmful medications as miracle cures. We also talk about treatment (and it's more than "I wanna hold your hand," song choice hint) Links: Moral Injury Fact Sheet: Moral Injury in Health Care Workers: Health and Human Services: Moral Injury for Healthcare Workers: Gender differences in Moral Injury Moral Injury in the Wake of Coronavirus: Attending to the Psychological Impact of the Pandemic on Healthcare Workers: Moral Injury

During the winter peak in coronavirus cases, things got busy in my hospital, but nothing close to what happened in places like New York City last spring or Los Angeles this winter. Hospitals in these places went way past their capacity, but did this strain on the system lead to worse outcomes? Absolutely. On today's podcast, we talk with Brian Block, lead author of a Journal of Hospital Medicine study that showed that patients with COVID-19 admitted to hospitals with larger COVID-19 patient surges had an increased odds of death. We talk about the findings in his study, which also included some variation in the surge hospitals as well as potential reasons behind these outcomes. We've also invited two other guests, Denise Barchas and Sunita Puri, to describe their hospital experiences in a COVID surge. Denise is a ICU nurse at UCSF who volunteered in New York during the spring surge of COVID cases. Sunita is the Medical Director of Palliative Medicine at USC's Keck Hospital & Norris Cancer Center in Los Angeles. She is also the author of numerous books and essays, including "That Good Night: Life and Medicine in the Eleventh Hour" (if you haven't read it yet you should!)

We know from study after study that most older adults would prefer to age in place, in their homes, with their families and embedded in their communities. But our health system is in many ways not particularly well set up to help people age in place. Medicare does not routinely require measurement or tracking of disability that leads many people to move out of their homes, and many interventions that support people to age in place are unfunded, underfunded, or funded by philanthropy rather than the government. Today we talk with Sarah Szanton, who created the CAPABLE multi-disciplinary model to help older adults stay at home, and Kenny Lam, who used a national study to examine the need for home-modification devices. And we preview another of the AGS songs for the literature update - this one to the tune of "My Get up and Go" by Pete Seeger. Enjoy! -@AlexSmithMD

There are no currently approved disease modifying drugs for Alzheimer's disease, but in a couple months that may change. In July of 2021, the FDA will consider approval of a human monoclonal antibody called Aducanumab for the treatment of Alzheimer's disease. If approved, it will not only make this drug the defacto standard of care for Alzheimer's disease, but will create a monumental shift in the usage of other currently limited diagnostic tests, including Amyloid PET scans and other biomarkers. On today's podcast, we talk about all things Amyloid, including Aducanumab and Amyloid PET scans with Gil Rabinovici. Dr. Rabinovici is the Edward Fein and Pearl Landrith Endowed Professor in Memory & Aging at UCSF. I could talk to Gil all day long, but we try to fit all of these topics in this jam-packed podcast: The heterogeneity of dementia and potentially Alzheimer's disease Where are we now with disease modifying treatments for Alzheimer's disease The Role of Amyloid PET scans and other biomarkers both now and in the future The wild story Aducanumab and the controversy surrounding its pending FDA approval

One of our earliest COVID podcasts with Jim Wright and David Grabowski a year ago addressed the early devastating impact of COVID on nursing homes. One year ago Mike Wasserman, geriatrician and immediate past president of the California Long Term Care Association, said we'd have a quarter million deaths in long term care. A quarter of a million deaths. No one would publish that quote - it seemed inconceivable to many at the time. And now, here we are, and the numbers are going to be close. In this podcast we look back on where we've been over the last year, where we are now, and what's ahead. One theme that runs through the podcast is that if this level of death, confinement, and fear occured to any other population, change would have been swift. But nursing home residents, for the most part, don't have a voice, they're not able to speak up, they lack power to move politicians and policy. Mike Wasserman is a provocateur. He is a needed voice for the nursing home residents and the nursing home staff who often are not able to speak for themselves. He is regularly quoted in major news outlets, and was in the Washington Post about opening up nursing homes to visitation the day of our podcast. If you don't follow him on Twitter @Wassdoc you should! -Link to Wassmerm and Grabowski's article in the Health Affairs blog on the need for financial transparency in nursing homes. -Link to webinar about what to do about COVID in long term care from April 2020 -@AlexSmithMD