GeriPal - A Geriatrics and Palliative Medicine Podcast

We've had multiple GeriPal episodes about treatments for dementia, including aducanumab (here, here, and here) and lecanemab (here). As today's guest, Kristine Yaffe notes, part of the reason for that emphasis is that in the US we prioritize treatment, whereas other countries are ahead of us in prioritizing prevention. Deb Barnes and Kristine Yaffe published a landmark paper in Lancet Neurology finding that up to half of dementia risk is due to modifiable factors. If we focused on prevention, from a public health standpoint, we would achieve far more than spending millions billions on treatment. Today we talk about steps we can and should take to reduce the risk of dementia, including: Education and cognitive games (I reveal my embarrassingly poor average time on the NYT mini cross word) Physical activity Sleep Depression Smoking Social isolation Blood pressure control (listen also to our podcast on Sprint Mind with Jeff Williamson) We also delve into an exciting new trial Kristine led with others on the impact of risk factor reduction on cognition - here's a link to press about the trial from a fall meeting presentation - article forthcoming. And because we can't resist, we dip into aducanumab and lecanemab at the end. -@AlexSmithMD

I haven't worked with many adolescents and young adults (AYA, roughly teens to twenties). But when I have, I find that they're often some of the hardest patients to care for. Why? We talk about why it's so hard with Abby Rosenberg (chief of PC at DFCI and Boston Childrens), Nick Purol (clinical social worker at DFCI and Boston Childrens), Daniel Eison (pediatric PC doc and co-host of PediPal). We are grateful to Andrea Thach (PC doc at Sutter East Bay) for bringing this topic to our attention and for asking questions as a guest host. Here are just a few of the explanations for why it's so hard: They are closer in age to some of us (younger clinicians). Countertransference hits hard. There's an in-between space between adolescence and adulthood - and there's something that we identify with in that in-between space, tugging at our heart strings Everyone has been a teenager. Everyone has lived through their early 20s. Every member of the interdisciplinary team. Adolescence and young adulthood is a romanticized time of life in our culture. We remember bucking the rules, figuring out who you are, hair on fire, feeling invulnerable, trying to figure out who you are - and now those adolescents are stuck in the hospital, with doctors and parents telling them what to do, having their autonomy crushed by the medical institution, realizing they're not invulnerable. We talk about these issues and more - what resources to leverage, how to cope as a team. We in geriatrics and adult palliative care clinicians have so much to learn from our colleagues in pediatrics - and though many of these lessons are specific to adolescents and young adults - many of the lessons are valuable for the care of patients in older life stages. Links to resources for working with AYA, from Nick Purol): The Courageous Parents Network has a wealth of information/resources/videos/articles on many overlapping issues and topics related to caring for children/adolescents/young adults with serious illness (from both the provider and clinician perspective): https://courageousparentsnetwork.org Courageous Parents Network Empowering parents caring for children with serious illness through video, shared community, professional guidance, and palliative care. You are Not Alone. courageousparentsnetwork.org Voicing My Choices is a wonderful tool for discussing goals/wishes and introducing advance directives in the context of serious illness. It's based off 5 Wishes and validated for AYA through direct feedback from the population: https://store.fivewishes.org/ShopLocal/en/p/VC-MASTER-000/voicing-my-choices The Oxford Textbook of Palliative Social Work has several chapters relating to working with AYA (either due to family illness or their own), with many psychosocial clinicians in our field contributing: https://www.amazon.com/Oxford-Textbook-Palliative-Social-Work/dp/0197537855 Same is true for the Interdisciplinary Pediatric Palliative Care Textbook: https://www.amazon.com/Interdisciplinary-Pediatric-Palliative-Joanne-Wolfe/dp/0190090014/ref=sr_1_1?crid=33YG2UAKDZ8DO&keywords=interdisciplinary+pediatric+palliative+care&qid=1682288312&s=books&sprefix=interdisciplinary+pediatric+palliative+car%2Cstripbooks%2C101&sr=1-1&asin=0190090014&revisionId=&format=4&depth=1 -@AlexSmithMD

We have a special extra podcast this week. During the last AAHPM - HPNA meeting in Montréal, we went around asking attendees what one thing that they are most worried about and one thing they are most hopeful for when thinking about the future of our field. We couldn't fit everyone's responses in but came up with the big themes for questions and edited them into this weeks podcast / YouTube video. Eric and Alex DISCLAIMER While we filmed in Montreal during the Annual Assembly, all opinions expressed in this podcast are independent of AAHPM and HPNA, or the Annual Assembly. Furthermore, direction to external websites is not an endorsement from AAHPM or HPNA, or the Annual Assembly. Palliative Care the Next Generation: How the Service May Grow and Evolve https://hospicenews.com/2023/04/14/palliative-care-the-next-generation-how-the-service-may-grow-and-evolve/ AccentCare, a portfolio company of private equity firm Advent International, is another example. The company has expanded its palliative care services through partnerships with hospitals and other managed care providers, according to AccentCare CEO Stephan Rodgers. "We've got a very large palliative care practice," Rodgers told PCN. "What we've seen to make it really work is you either have to be in the hospital, where we've taken over palliative care in the hospital, or you have to be contracted with managed care and get it at some kind of risk, because community-based palliative care is very difficult to make operate right now from a profitable [perspective]."

In 1990 11% of homeless persons were older than 50. Today half are over age 50. Today we talk with Margot Kushel about how we got here, including: That sense of powerlessness as a clinician when you "fix up" a patient in the hospital, only to discharge them to the street knowing things will fall apart. Chronic vs acute homelessness What is the major driver of homelessness in general? What is the major driver of the increase in older homeless persons? Why do we say "over 50" is "older" for homeless persons, why not 65? To what extent is the rise of tech in San Francisco to blame for our local rise in homelessness? What are the structural factors and individual factors that contribute to homelessness? How has the history of redlining and the federal tax subsidy of wealthy (mostly white) people in the form of a mortgage interest deduction contributed to racial inequalities in homelessness? What can we do about it? What are the highest yield interventions and policy changes? What should we call it - homeless or unhoused? We were fortunate to make it to the end of this podcast before Margot lost power. It's storming again in the Bay Area at the time we record this. So much harder than for the older homeless people on the streets with no power to lose. A mad world out there (song hint). Key references: -Margot Kushel's UCSF Grand Rounds -JAMA IM paper on mortality among older homeless persons -NEJM perspective arguing that interventions to address homelessness shouldn't be evaluated on cost savings. -@AlexSmithMD

Social connections impact our health in profound ways, whether it is the support we receive from family and friends in navigating serious illness, the joy from shared social activities, or connecting with our community. Experiencing social isolation, the objective lack of contact with friends, family, or the community, or loneliness, the subjective feeling of lacking companionship or feeling left out, may be signs that our overall social life is struggling. But, should we as clinicians care about the social lives of our patients? Are there meaningful ways of assessing loneliness and social isolation in clinical settings and connecting patients with interventions? How can public health and policy experts address these needs, particularly in light of the COVID-19 pandemic which turned our social lives upside down? On today today's podcast, we are joined by guest host and UCSF geriatrician Ashwin Kotwal as we welcome three renowned scholars in the field: 1) Dr. Julianne Holt-Lunstad, Professor of Psychology and Neuroscience at Brigham Young University, an international expert on loneliness, social isolation, and social interventions, who has served on the National Academy of Sciences committee on social isolation and loneliness and advised the UK Loneliness Campaign, 2) Dr. Thomas Cudjoe, Assistant Professor of Medicine at Johns Hopkins University, who has conducted groundbreaking work on the measurement of social isolation and mechanisms of impact on health, and 3) Dr. Carla Perissinotto, Professor of Medicine at UCSF, who has pioneered the clinical and policy approach to addressing loneliness and social isolation. We talk about: Their personal and clinical inspiration for studying loneliness and social isolation, and hurdles encountered in bringing these needs to the clinical world. The Listening "EAR" approach that simplifies assessment of loneliness and social isolation in clinical settings, and other practical pointers. Check out some of their recent work, including: Dr. Holt-Lunstad's and Dr. Perissinotto's powerful perspective piece in the New England Journal of Medicine which provides a clinical framework for addressing loneliness and social isolation. Dr. Cudjoe's recent work demonstrating the impact of social isolation on dementia risk, populations at risk, and how our social lives "getting under our skin." Dr. Kotwal's work showing how social isolation impacts end-of-life health care use, including hospice and acute care. We touch briefly on (and build on) topics discussed in prior podcasts such as loneliness during the pandemic. Tune in to hear Alex's acoustic rendition of Outkast's Hey Y'All! -Ashwin Kotwal

Do we need an RCT to establish the worth of chaplaincy? Einstein once said, "Everything that can be counted does not necessarily count; everything that counts cannot necessarily be counted." A friend of GeriPal, and prior guest, Guy Micco commented today that we need an RCT for chaplaincy is like the idea that the humanities need to justify their value in medical training: "It's like being told to measure the taste of orange juice with a ruler." On the other hand, all of our guests agree that chaplains are often the most vulnerable to being cut from hospital and health system budgets. These studies are important. Today we have a star-studded lineup, including Lexy Torke of Indiana University, who discusses her RCT of a chaplaincy intervention for surrogates of patients in the ICU, published in JPSM and plenary presentation at AAHPM/HPNA. To provide context, we are joined by Karen Steinhauser, a social scientist at Duke who has been studying spirituality for years (and published one of the most cited papers in palliative care on factors considered important at the end of life, as well as one of my favorite qualitative papers to give to research trainees). We are also joined by LaVera Crawly, a physician turned chaplain, now VP of Spiritual Care at Common Spirit Health (and author of another of my favorite and most cited papers on palliative care in the African American Community). We dive into the issues of measuring spirituality, chaplaincy, the need for an expanded vocabulary around spirituality, spiritual assessments, spiritual history, LaVera's journey from physician to chaplain (listen to her compelling answer to the magic wand question at the end). For further context, please check out our prior podcast on spirituality, and this discussion of the RCT by Lexy that I helped moderate for Transforming Chaplaincy. Thanks to my son Kai for playing the guitar part in 5/4 with strange chords on Riverman by Nick Drake! -Alex

Two weeks ago on the GeriPal podcast we talked about why and how to write for the general public. This week we've invited three guests to share their stories about storytelling that's written for healthcare providers. The first guest is Liz Salmi. Liz wrote a fabulous perspectives piece in the NEJM titled "Deciding on My Dimples" which talks about her experience as a patient doing shared decision making during neurosurgery for resection of an astrocytoma. In addition to this being a fascinating story, Liz brings in a great perspective as a patient, advocate, researcher, and a punk rocker. Our second guest is a recurring star of GeriPal, Anne Kelly. She just published an essay for JAMA Piece of My Mind titled "The Last Visit". In this piece Anne describes her experience with the expressions of love she and her mother shared in the last days of her mothers life. Lastly, but certainly not least, we've invited Preeti Malani. Preeti is the editor for JAMA's Piece of My Mind section. We've asked Preeti to come on to describe what happens behind the curtain when evaluating these stories, including what makes those few that get accepted stand out. We've also love to hear from you on twitter and facebook your own experiences writing for the medical world (and please include links!)

In November of 2022, Ava Kofman published a piece in the New Yorker titled "How Hospice Became a For-Profit Hustle." Some viewed this piece as an affront to the amazing work hospice does for those approaching the end of their lives by cherry picking stories of a few bad actors to paint hospice is a bad light. For others, this piece, while painful to read, gave voice to what they have been feeling over the last decade - hospice has in some ways lost its way in a quest of promoting profit over care. On today's podcast, live from the American Academy of Hospice and Palliative Medicine Annual Meeting, we invite two thought leaders in the field, Ira Byock and Joseph Shega, to discuss among other things: Is hospice losing its way? Is there a difference between for-profit and not-for-profit when it comes to quality of care? What is our role as hospice and palliative care providers in advocating for high-quality hospice care? If you are interested in signing the position statement "Core Roles and Responsibilities of Physicians in Hospice Care", click here. For a deeper diver into these issues, check out some of the following links: Ira's Stat new article "Hospice care needs saving" GeriPal's episode on the growing role of private equity in hospice care Acquisitions of Hospice Agencies by Private Equity Firms and Publicly Traded Corporations. JAMA IM 2021 Hospice Acquisitions by Profit-Driven Private Equity Firms. JAMA Health Forum. 2021 Association of Hospice Profit Status With Family Caregivers' Reported Care Experiences. JAMA IM 2023 A shout-out to my NPR episode on 1A titled the "State of Hospice Care" DISCLAIMER While we filmed in Montreal during the Annual Assembly, all opinions expressed in this podcast are independent of AAHPM and HPNA, or the Annual Assembly. Furthermore, direction to external websites is not an endorsement from AAHPM or HPNA, or the Annual Assembly. ---------------------------

So you want to write a book. So you want to write a book! So…you want to write a book?!? Today we talk with two geriatricians: Rosanne Leipzig, author of Honest Aging: An Insider's Guide to the Second Half of Life; and Louise Aronson, author of Elderhood: Redefining Aging, Transforming Medicine, and Reimagining Life. (You can hear our prior podcast on Louise's book here). We talk with them about writing for the lay public, including: Why write a book for the lay public? Why write about aging? Was there pushback from publishers (hint: hell yes) What terms to use to describe the "old age" time period? How did they start writing a book? How do you find time to write and also be doctors and academic professors? Revisions and working with editors Writing an Op Ed - how to start, what to write, where to send it TheOpEdProject as a resource for learning more We look forward to the books and op-eds our listeners will write! In all seriousness, you don't actually have to want to write a book to be interested in this podcast. You don't have to want to play professional basketball to appreciate The Last Dance, which documents the final season of Michael Jordan with the Chicago Bulls. These are inherently interesting interviews because the motivations, process, and struggle of monumental undertakings are interesting in and of themselves. Enjoy! -@AlexSmithMD

Psychedelics are having a moment. Enthusiasm is brimming. Legalization is moving forward in several states, following the lead of Oregon and Colorado. FDA is considering approval, shifting away from Schedule I restrictions, paving the way for use in clinical practice. Potential use in palliative care, chronic pain, and for mood disorders is tantalizing. Early data on efficacy in patients with anxiety and demoralization are promising. Research is exploding. Two of our guests today, Stacy Fischer and Brian Anderson, are involved in large multicenter trials of psychedelics for patients with advanced cancer (Fischer) or life-limiting illness (Anderson). Theora Cimino conducted an observational study (publication in the works) of marginally housed/homeless persons many of whom had experience with psychedelics. And yet there are reasons for caution. In our prior podcast with Ira Byock on psychedelics in 2019 we talked primarily about the potential of psychedelics. Today we largely focus on reasons for caution, including: We know almost nothing about psychedelics in older adults - only about 1% of patients in published trials were older adults, much less older adults with multiple chronic conditions, multiple medications, and frailty. Bree Johnston and Brian Anderson wrote a terrific summary of the evidence (or lack thereof) in older adults. There is a marked lack of diversity in published trials. Most participants are White and well-resourced. Psilocybin, the most commonly used psychedelic, increases heart rate and blood pressure, which may potentially lead to cardiovascular events. The efficacy of psychedelics without therapy, and the impact of variations in therapy type, training, duration, is unknown. Ethical issues, including colonization of psychedelics by big pharma. Psychedelics have been used by communities around the globe for hundreds of years (or more). We cover these issues and more in today's podcast. Note, I butchered the chorus on the YouTube version - please listen to the podcast for my souped up version with drums and bass! -@AlexSmithMD