
Probably Science
Professional comedians with so-so STEM pedigrees take you through this week in science. Incompetently. Featuring hosts Matt Kirshen, Andy Wood (and sometimes Jesse Case or Brooks Wheelan) along with a rotating cast of special guests from the worlds of comedy and science.
Latest episodes

Aug 29, 2024 • 1h 12min
Episode 543 - Frank Conniff
Mystery Science Theater alum, comedian and author Frank Conniff (@FrankConniff) joins the crew to talk about his new audiobook Dark Apnea. Plus horoscope doubts! Carl Sagan predicting the future! And where dinosaur killing asteroids came from! In the patreon bonus ep we talk about saving the banana from extinction. Sign up here!

Aug 21, 2024 • 1h 18min
Episode 542 - Mark Cohen
Comedian Mark Cohen (@mark_coco_cohen) joins Jesse, Andy and Matt to discuss the two aging bursts humans experience, restoring Tonka trucks, weaning crocodiles off of cane toads, Mark's video game creations, using slime mold to help map dark matter, and stock photo artists who play Lawn Mowing Simulator. and Mark's possible record-breaking stint at The Comedy Cellar in Las Vegas.

Aug 10, 2024 • 1h 9min
Episode 541 - Isak Allen
Neuroscientist-turned-comedian Isak Allen (@isakallen) joins Matt, Jesse and Andy to talk about smashing flies, using fMRI to study brain activity as it relates to music and comedy, tonal languages, the Dong Song, Neuralink, dystopian futures and Isak's new Dry Bar special Culturally Unavailable.

Aug 4, 2024 • 1h 23min
Episode 540 - The Sports Gene with David Epstein and Paul Morrissey (re-release)
We've got just the prescription for everyone out there with Olympic fever: A re-release of a 2013 episode in which Matt and Andy interview David Epstein, a Sports Illustrated journalist and the author of the outstanding book The Sports Gene, along with college basketball player-turned-comedian Paul Morrissey, to discuss the field of sports genetics research and try to get to the bottom of how elite athletes are made. Enjoy!

Jul 29, 2024 • 1h 15min
Episode 539 - Cathy Ladman
Comedy legend Cathy Ladman (@cathyladman1) joins Jesse, Andy and Matt to talk about creepy Foundation for a Better Life billboards, cancer battles, 1970s acid, the CrowdStrike software crash, how propofol tips your brain into chaos, the merits of comedy classes, Brazilian cocaine sharks and Cathy's September 7th Vegas show.

Jul 18, 2024 • 1h 12min
Episode 538 - David Brown
Producer David Brown joins Jesse, Matt and Andy to talk about creating entertaining science programming, the new Peacock show The Hungry Games: Alaska's Big Bear Challenge that David produced, Rhys Darby narrated and Matt and Andy worked on, the Emmy-winning pop-science show Could You Survive The Movies?, Andy's Top Gun cameo, Fat Bear Week, Goro's pecs, a south-of-the-border Orson Welles experience, using AI to figure out the sperm whale phonetic alphabet, Larry the cat and Boris Johnson and The Higgins Boys & Gruber.

Jul 14, 2024 • 1h 6min
Episode 537 - Todd Barry
Comedian Todd Barry (@toddbarry) joins Matt, Andy and Jesse to talk about his new special Domestic Shorthair, an FDA ban of a citrus soda ingredient, ginger ale vs. ginger beer, the quackery of Dr. Idz, new images of an asteroid that just whizzed by Earth, Jesse's air force base food poisoning story, whether toxoplasmosis causes crazy cat lady syndrome and Jackson Galaxy's Cat Camp.

Jul 6, 2024 • 58min
Episode 536 - Sid Singh
Comedian Sid Singh (@mrsidsingh) joins Andy, Jesse and Matt to talk about being a Brexit and Biden bellwether, Mozart the millenial, weird tunings, 432 Hz bullshit, old-ass Washington cherries, SPATS updates, a clever way to curb rhino horn poaching, meat rice, debunking Novi's etymology and ant surgeons.

Jun 28, 2024 • 1h 12min
Episode 535 - Jordan Morris
Writer/podcaster Jordan Morris (@Jordan_Morris) returns to the show to talk with Matt, Jesse and Andy about his upcoming graphic novel Youth Group, the YA genre, hawk tuah, breakdancing in the Olympics, elephants calling each other by name, wartime magicians, GPT-4 passing the Turing Test, using AI to cancel customer anger, a new stab at AI alignment and creating plasma fireballs in the lab.

Jun 21, 2024 • 52min
Episode 534 - Bobcat Goldthwait, Rhys Darby, Dr. Farah Alibay and Natalia Reagan
Matt and Andy host a live installment of the podcast from To 29 and Beyond in Twentynine Palms featuring guests Bobcat Goldthwait, Rhys Darby, Dr. Farah Alibay and Natalia Reagan, digging into topics including indoor rocketry, opening for Nirvana, projectile bibles, the Cryptid Factor podcast, Bobcat's Bigfoot movie, 10 Million Dollar Bigfoot Bounty, Robin Williams and Koko the gorilla, Mars landers, returning samples to Earth, and Dr. Alibay's work on the upcoming NASA/JPL all-sky spectral survey project SphereX.
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