Evolution 2.0

Doru Paul of Cornell University is one of those very rare people who has both treated over 10,000 cancer patients as their doctor and simultaneously holds a kaleidoscopic view of a huge range of research, theories, and literature. Today we talk about the many competing models and their pros and cons. And, finally, he answers the question: “What kind of medical policies would you put in place if you could start your own country from scratch?”.LINKS:Official version: https://www.sciencedirect.com/science/article/abs/pii/S0079610721000419Free version: https://evo2.org/cancer-as-a-form-of-life Credentials: https://weillcornell.org/doru-m-paul-md-phd Hosted on Acast. See acast.com/privacy for more information.

Today I don’t have a guest, but what I do have is a really excellent PDF submitted to me by aPerry Marshall. Perry, has been a really successful marketer, I’ve been following him for12 years, he has been doing it for maybe, close to 20 years. He started off teaching GoogleAdWords, Google Pay-Per-Click, and moved on to Facebook advertising, and eventually, I startedhearing from him that he was studying evolutionary biology and I read his book, Evolution 2.0. Itbrought out a lot of super interesting topics in biology that I just didn’t know about and it waspart of my inspiration to do the podcast as well and to this day, having done almost 3,000interviews, I credit Perry and Evolution 2.0 for kind of getting me started on the path. So Perrynow has been working on cancer, not directly but he is working on helping to promote a newand what I think is probably a better understanding of cancer and as you know, if you are alistener of this podcast, I am getting close to finishing my book on cancer....https://bit.ly/high-speed-evolutionary-mechanisms-pdfhttps://mma.prnewswire.com/media/1583603/Natural_Code_popular_evolution_books.pdf Hosted on Acast. See acast.com/privacy for more information.

Psychic phenomena have been meticulously documented in hundreds of controlled studies since the 1980s. Mainstream science publications resist acknowledging this but the quality and quantity of evidence is overwhelming. Dean Radin, who has a bachelor’s degree in electrical engineering and a Ph.D. in Psychology, began discovering this decades ago and founded the Institute for Noetic Sciences. He recently joined forces with eminent scientist Stuart Kauffman to harmonize the observations with quantum theory. In this paper, the two scientists swing for the fences and attempt to unify consciousness, psychic phenomena, and quantum mechanics. https://arxiv.org/abs/2101.01538 Dean and I discuss the implications of this.   Hosted on Acast. See acast.com/privacy for more information.

There are very very few people who can slice through the jargon of molecular biology and explain how cells talk to each other in a way that a high school student can understand. But Jon Lieff has done exactly that and his book, NAME, is a guided tour of a microscopic world that is bursting with life... and stories...This book may change the way you see everything. Jon Lieff's Website: https://jonlieffmd.com/Jon Lieff's Book: The Secret Language of Cellshttps://jonlieffmd.com/book/the-secret-language-of-cells Hosted on Acast. See acast.com/privacy for more information.

A new book by MIT Press stresses the urgency of approaching cancer from new angles. Some are completely new. Others are 100 years old and never given the attention they deserve. Bernhard and I discuss his motivations for taking on this project and how complex systems are much more subtle than we humans prefer to believe. Bernhard Strauss' Book: Rethinking Cancerhttps://mitpress.mit.edu/books/rethinking-cancer Hosted on Acast. See acast.com/privacy for more information.

Jenny Davis is a professional athlete from Scotland who found out she had bowel cancer 9 months ago. She tells her very personal story of chemotherapy treatments, introspection, detox, and our broken medical system.  https://www.jennydavis.org/ https://meganmacedo.com/ Hosted on Acast. See acast.com/privacy for more information.

John Sonmez interviews Perry Marshall and they discuss why it’s impossible for computers in their current form to become conscious; how modern mathematics speaks in a new way to age-old questions about free will; the nature of consciousness; the origin of life and the very nature of reality itself. All this is based on Perry’s paper “Biology transcends the limits of computation. Hosted on Acast. See acast.com/privacy for more information.

Rich Jacobs indulged his fascination with technology by starting a podcast called Finding Genius. He didn’t know that it would end up taking him into hundreds of specialties in science, technology, and medicine. His book titled Finding Genius: Understanding Viruses: 30 Questions, 25 Geniuses, 100 Amazing Insights is a beautifully edited compilation of Q&A from some of the best virus people in the world. Here we explore what Rich discovered about viruses and their experts. Hosted on Acast. See acast.com/privacy for more information.

Eric Kuelker Ph.D. R.Psych. discusses reliable but little-known research linking cancer and heart disease to traumatic life events and stress. It turns out that psychotherapy and relationship repair reduces the chances of cancer and factors like marriage extend life more than medical treatments do. This may extend it down to the cellular level.Eric’s website is https://psychologicalinjuryindex.com/References:Hughes K, Bellis MA, Hardcastle KA, Sethi D, Butchart A, Mikton C, Jones L, Dunne MP. (2017) The effect of multiple adverse childhood experiences on health: a systematic review and meta-analysis. Lancet Public Health. Aug;2(8):e356-e366. https://pubmed.ncbi.nlm.nih.gov/29253477/Roberts AL, Huang T, Koenen KC, Kim Y, Kubzansky LD, Tworoger SS. (2019) Post-traumatic stress disorder is associated with increased risk of ovarian cancer: A prospective and retrospective longitudinal cohort study. Cancer Res. Oct 1;79(19): 5113-5120. https://pubmed.ncbi.nlm.nih.gov/31488422/ Lu D, Sundström K, Sparén P, Fall K, Sjölander A, Dillner J, Helm NY, Adami HO, Valdimarsdóttir U, Fang F. (2016). Bereavement is associated with an increased risk of HPV infection and cervical cancer: An epidemiological study in Sweden. Cancer Res. Feb 1;76(3): 643-51. https://pubmed.ncbi.nlm.nih.gov/26634926/Flaherty RL, Owen M, Fagan-Murphy A, Intabli H, Healy D, Patel A, Allen MC, Patel BA, Flint MS. (2017) Glucocorticoids induce production of reactive oxygen species/reactive nitrogen species and DNA damage through an iNOS mediated pathway in breast cancer. Breast Cancer Res. Mar 24;19(1):35. https://pubmed.ncbi.nlm.nih.gov/28340615/ Morath J, Moreno-Villanueva M, Hamuni G, Kolassa S, Ruf-Leuschner M, Schauer M, Elbert T, Bürkle A, Kolassa IT. (2014) Effects of psychotherapy on DNA strand break accumulation originating from traumatic stress. Psychotherapy and Psychosomatics. 83(5):289-97. https://pubmed.ncbi.nlm.nih.gov/25116690/ Bellis MA, Hughes K, Ford K, Ramos Rodriguez G, Sethi D, Passmore J. (2019) Life course health consequences and associated annual costs of adverse childhood experiences across Europe and North America: a systematic review and meta-analysis. Lancet Public Health. Oct;4(10): e517-e528. https://pubmed.ncbi.nlm.nih.gov/31492648/Ziegler C, Richter J, Mahr M, Gajewska A, Schiele MA, Gehrmann A, Schmidt B, Lesch KP, Lang T, Helbig-Lang S, Pauli P, Kircher T, Reif A, Rief W, Vossbeck-Elsebusch AN, Arolt V, Wittchen HU, Hamm AO, Deckert J, Domschke K. (2016). MAOA gene hypomethylation in panic disorder: Reversibility of an epigenetic risk pattern by psychotherapy. Transl Psychiatry. Apr 5;6(4):e773. doi: 10.1038/tp.2016.41 https://pubmed.ncbi.nlm.nih.gov/27045843/Roberts S, Lester KJ, Hudson JL, Rapee RM, Creswell C, Cooper PJ, Thirlwall KJ, Coleman JR, Breen G, Wong CC, Eley TC. (2014). Serotonin transporter [corrected] methylation and response to cognitive behavior therapy in children with anxiety disorders. Transl Psychiatry. Sep 16;4(9):e444. https://pubmed.ncbi.nlm.nih.gov/25226553/Roberts S, Keers R, Breen G, Coleman JRI, Jöhren P, Kepa A, Lester KJ, Margraf J, Scheider S, Teismann T, Wannemüller A, Eley TC, Wong CCY. (2019). DNA methylation of FKBP5 and response to exposure-based psychological therapy. Am J Med Genet B Neuropsychiatr Genet. Mar;180(2):150-158. https://pubmed.ncbi.nlm.nih.gov/30334356/Levy-Gigi E, Szabó C, Kelemen O, Kéri S. (2013). Association among clinical response, hippocampal volume, and FKBP5 gene expression in individuals with posttraumatic stress disorder receiving cognitive behavioral therapy. Biol Psychiatry. Dec 1;74(11): 793-800. doi: 10.1016/j.biopsych.2013.05.017 https://pubmed.ncbi.nlm.nih.gov/23856297/Quidé Y, Witteveen AB, El-Hage W, Veltman DJ, Olff M. (2012). Differences between effects of psychological versus pharmacological treatments on functional and morphological brain alterations in anxiety disorders and major depressive disorder: A systematic review. Neurosci Biobehav Rev. Jan;36(1): 626-44. https://pubmed.ncbi.nlm.nih.gov/21963442/Bossini L, Santarnecchi E, Casolaro I, Koukouna D, Caterini C, Cecchini F, Fortini V, Vatti G, Marino D, Fernandez I, Rossi A, Fagiolini A. (2017). Morphovolumetric changes after EMDR treatment in drug-naïve PTSD patients. Riv Psichiatr. Jan-Feb;52(1): 24-31. https://pubmed.ncbi.nlm.nih.gov/28287194/Aizer AA, Chen MH, McCarthy EP, et al. Marital status and survival in patients with cancer. (2013) J Clin Oncol. 31: 3869‐3876. https://pubmed.ncbi.nlm.nih.gov/24062405/Mirosevic S, Jo B, Kraemer HC, Ershadi M, Neri E, Spiegel D. (2019). "Not just another meta-analysis": Sources of heterogeneity in psychosocial treatment effect on cancer survival. Cancer Med. Jan;8(1): 363-373. https://pubmed.ncbi.nlm.nih.gov/30600642/https://www.health.harvard.edu/heart-health/the-genetics-of-heart-disease-an-updateLevin M (2019) The Computational Boundary of a “Self”: Developmental Bioelectricity Drives Multicellularity and Scale-Free Cognition. Front. Psychol. 10:2688. https://pubmed.ncbi.nlm.nih.gov/31920779/ Hosted on Acast. See acast.com/privacy for more information.

Rob Berkley left this earth in December 2019 as a result of cancer. 58. Rob was THE most empathic and warm-hearted individual in the entire marketing space (I’m not exaggerating). When you would sit down with him you would feel his warmth focusing on you like an infrared heat lamp. He was one of my most valuable business advisors. Being trained by him and Victor Cheng was like having Oprah and Stephen Hawking together in the same room.Stormy weather nearly prevented me from making his memorial at Martha’s Vineyard, but I managed to snag the boat ride and I’ll never forget the December 18 solstice sun streaming through the windows at his somber yet joyful gathering.The other thing I will never forget is meeting his wife Debbie for the first time, right there at his memorial service. I had heard much about her, and she had heard about me, but we had never crossed paths.I approached her in their kitchen and introduced myself. “Perry! I am so delighted to meet you!” She faced me squarely, looked deep into my eyes, and connected, human to human. I instantly felt the jolt of her conviction and aliveness. She wrapped her arms around me, embraced me, and welcomed me as though I were a friend of 25 years. Her energy was so palpable I was momentarily startled.It only makes sense that Rob would marry a woman like Debbie.Today I would like to share Rob’s last interview with you: a very candid conversation between Rob, Debbie, and their caregiver and collaborator Meredith, describing humility and courage in the face of a terminal diagnosis. Hosted on Acast. See acast.com/privacy for more information.