Chris Mason is a professor of genomics, physiology, and biophysics at Cornell, doing research on the long-term effects of space on the human body. He is the author of The Next 500 Years: Engineering Life to Reach New Worlds. Please support this podcast by checking out our sponsors: – BetterHelp: https://betterhelp.com/lex to get 10% off – Grammarly: https://grammarly.com/lex to get 20% off premium – Magic Spoon: https://magicspoon.com/lex – Blinkist: https://blinkist.com/lex – Eight Sleep: https://www.eightsleep.com/lex EPISODE LINKS: Chris’s Twitter: https://twitter.com/mason_lab Chris’s Website: http://masonlab.net/ Chris’s Company: https://onegevity.com/ The Next 500 Years (book): https://amzn.to/3k9ab4S Reasons and Persons (book): https://amzn.to/3Lrm6a5 PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: – Check out the sponsors above, it’s the best way to support this podcast – Support on Patreon: https://www.patreon.com/lexfridman – Twitter: https://twitter.com/lexfridman – Instagram: https://www.instagram.com/lexfridman – LinkedIn: https://www.linkedin.com/in/lexfridman – Facebook: https://www.facebook.com/lexfridman – Medium: https://medium.com/@lexfridman OUTLINE: Here’s the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. (0:00) – Introduction (7:43) – Human extinction awareness (16:29) – Heat death of the universe (22:05) – Alone in the universe (25:41) – Aliens (33:50) – Entropy goggles (48:04) – Genetics (56:14) – Scott Kelly (1:02:12) – Adapting to space (1:12:13) – Sex in space (1:14:46) – Colonizing planets (1:21:25) – Culture on Mars (1:25:51) – Commercial space flights (1:33:09) – Podcast in space (1:40:43) – Axiom Space (1:42:59) – Designing space experiments (1:49:49) – Robots in space (1:52:30) – Space exploration (1:56:28) – War in space (2:00:05) – Launch toward the Second Sun (2:06:14) – Chlorohumans (2:11:50) – Extreme microbiome project (2:18:17) – Space travel breakthroughs (2:30:15) – Clones (2:36:08) – AI age prediction (2:41:38) – Advice for young people (2:47:56) – Dark times (2:52:19) – Mortality (2:56:37) – Visiting ISS and deep space (2:57:46) – Meaning of life

David Buss is an evolutionary psychologist at UT Austin. He is one of the founders of the field of evolutionary psychology. His current research is on sex differences in mate selection, mate attraction, infidelity, and the emotions of jealousy, lust, and love. Please support this podcast by checking out our sponsors: – Notion: https://notion.com/startups  – ExpressVPN: https://expressvpn.com/lexpod and use code LexPod  – Roka: https://roka.com/ and use code LEX  – Onnit: https://lexfridman.com/onnit  – Indeed: https://indeed.com/lex  EPISODE LINKS: David’s Twitter: https://twitter.com/profdavidbuss David’s Website: https://labs.la.utexas.edu/buss/ When Men Behave Badly (book): https://amzn.to/3y3bRVM The Evolution of Desire (book): https://amzn.to/3kyBdTt Evolutionary Psychology (textbook): https://amzn.to/3LExU9e Derogation of Competitors (research paper): https://bit.ly/38G4LMa PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: – Check out the sponsors above, it’s the best way to support this podcast – Support on Patreon: https://www.patreon.com/lexfridman – Twitter: https://twitter.com/lexfridman – Instagram: https://www.instagram.com/lexfridman – LinkedIn: https://www.linkedin.com/in/lexfridman – Facebook: https://www.facebook.com/lexfridman – Medium: https://medium.com/@lexfridman OUTLINE: Here’s the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. (00:00) – Introduction (08:04) – Sex vs Violence (14:48) – Mating strategies (26:44) – Social construct of beauty (30:38) – Evolution of mating evaluation (34:40) – Mating selection desires (39:52) – Difficulties of monogamy (46:16) – Importance of male appearance (48:52) – Importance of wealth (52:08) – Penis and breasts (55:59) – Fashion (58:58) – Body objectification (1:06:33) – Wear sunscreen (1:13:29) – Gender (1:30:39) – What motivates humans (1:32:29) – Dominance and submissiveness (1:40:33) – Johnny Depp defamation trial (1:50:24) – Jealousy (1:58:45) – Mate poaching (2:02:58) – Polyamory (2:14:13) – Female vs Male sexuality (2:23:11) – Pornography (2:29:46) – Sex and Violence continued (2:38:55) – Cancel culture (2:50:38) – Elon Musk and Twitter (2:59:02) – Serial killers (3:04:55) – Advice for young people (3:16:57) – Love (3:22:57) – Mortality (3:27:40) – Meaning of life

Grimes is a musician, artist, singer, songwriter, producer, and director. Please support this podcast by checking out our sponsors: – Brave: https://brave.com/lex – Novo: https://novo.co/lex – Lambda: https://lambdalabs.com/lex – Public Goods: https://publicgoods.com/lex and use code LEX to get $15 off – Blinkist: https://blinkist.com/lex and use code LEX to get 25% off premium EPISODE LINKS: Grimes’s Twitter: https://twitter.com/Grimezsz Grimes’s Instagram: https://www.instagram.com/grimes PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: – Check out the sponsors above, it’s the best way to support this podcast – Support on Patreon: https://www.patreon.com/lexfridman – Twitter: https://twitter.com/lexfridman – Instagram: https://www.instagram.com/lexfridman – LinkedIn: https://www.linkedin.com/in/lexfridman – Facebook: https://www.facebook.com/lexfridman – Medium: https://medium.com/@lexfridman OUTLINE: Here’s the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. (00:00) – Introduction (08:24) – Identity (12:22) – Music production (25:13) – Spotify (29:55) – Experimental music (32:30) – Vision of future (45:04) – Motherhood (1:01:11) – Consciousness (1:16:01) – Love (1:21:52) – Metaverse (1:34:34) – Technology and bureaucracy (1:38:32) – Mortality (1:46:57) – Understanding evil (1:50:55) – Last person on Earth (1:53:33) – Dan Carlin (1:56:03) – Rise and Fall of the Third Reich (2:02:28) – Coolest human invention (2:03:49) – Advice for young people (2:07:01) – Meaning of life

Cristiano Amon is the CEO of Qualcomm, world-leader in 5G wireless communication and computation systems inside premium Android phones and other robots. Please support this podcast by checking out our sponsors: – Scale: https://scale.com/lex – Truebill: https://truebill.com/lex – BiOptimizers: http://www.magbreakthrough.com/lex to get 10% off – Four Sigmatic: https://foursigmatic.com/lex and use code LexPod to get up to 60% off – Fundrise: https://fundrise.com/lex EPISODE LINKS: Cristiano’s Twitter: https://twitter.com/cristianoamon Qualcomm’s Website: https://qualcomm.com PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: – Check out the sponsors above, it’s the best way to support this podcast – Support on Patreon: https://www.patreon.com/lexfridman – Twitter: https://twitter.com/lexfridman – Instagram: https://www.instagram.com/lexfridman – LinkedIn: https://www.linkedin.com/in/lexfridman – Facebook: https://www.facebook.com/lexfridman – Medium: https://medium.com/@lexfridman OUTLINE: Here’s the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. (00:00) – Introduction (06:43) – Football/soccer (07:38) – Smartphones (10:09) – 5G (26:27) – Snapdragon (32:45) – Apple and Google (37:19) – Future of Qualcomm (48:20) – Autonomous vehicles (50:05) – Robots (52:31) – Chip shortage (56:40) – Lawsuits (1:00:07) – Leadership (1:04:26) – Advice for young people (1:08:17) – Meaning of life

Sara Walker is an astrobiologist and theoretical physicist. Lee Cronin is a chemist. This is a conversation and debate about alien life and alien civilizations. Please support this podcast by checking out our sponsors: – Uncruise: https://uncruise.com/pages/lex – Linode: https://linode.com/lex to get $100 free credit – ExpressVPN: https://expressvpn.com/lexpod and use code LexPod to get 3 months free – ROKA: https://roka.com/ and use code LEX to get 20% off your first order – Athletic Greens: https://athleticgreens.com/lex and use code LEX to get 1 month of fish oil EPISODE LINKS: Sara’s Twitter: https://twitter.com/Sara_Imari Sara’s Website: http://emergence.asu.edu Lee’s Twitter: https://twitter.com/leecronin Lee’s Website: https://www.chem.gla.ac.uk/cronin Chemify’s Website: https://chemify.io PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: – Check out the sponsors above, it’s the best way to support this podcast – Support on Patreon: https://www.patreon.com/lexfridman – Twitter: https://twitter.com/lexfridman – Instagram: https://www.instagram.com/lexfridman – LinkedIn: https://www.linkedin.com/in/lexfridman – Facebook: https://www.facebook.com/lexfridman – Medium: https://medium.com/@lexfridman OUTLINE: Here’s the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. (00:00) – Introduction (07:47) – Aliens (21:53) – What is life? (29:35) – Assembly theory (52:03) – Math (1:03:45) – Communication with aliens (1:28:38) – Evolution of the universe (1:37:56) – Creating alien life (1:45:29) – Origin of life (1:52:29) – Before the Big Bang (1:59:22) – God (2:09:39) – Goal-directed behavior (2:27:37) – Time (2:35:54) – Free will and imagination (2:51:06) – UFO sightings (2:56:06) – Alien life forms debate (3:11:14) – Robots (3:20:29) – Love and emotion (3:38:55) – Beauty in science (3:49:06) – Random questions (3:58:30) – Advice for young people (4:01:48) – Life on Earth (4:06:12) – Memory

Skye Fitzgerald is a two-time Oscar-nominated documentary filmmaker, his films include Hunger Ward, Lifeboat, and 50 Feet from Syria. Please support this podcast by checking out our sponsors: – Notion: https://notion.com/startups to get up to $1000 off team plan – Mizzen+Main: https://mizzenandmain.com and use code LEX to get $35 off – BetterHelp: https://betterhelp.com/lex to get 10% off – Onnit: https://lexfridman.com/onnit to get up to 10% off – Eight Sleep: https://www.eightsleep.com/lex and use code LEX to get special savings EPISODE LINKS: Skye’s Twitter: https://twitter.com/spin_film Skye’s Instagram: https://instagram.com/spin_film Hunger Ward (movie): https://hungerward.org Lifeboat (movie): https://lifeboatdocumentary.com 50 Feet from Syria (movie): https://50feetfromsyria.com PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: – Check out the sponsors above, it’s the best way to support this podcast – Support on Patreon: https://www.patreon.com/lexfridman – Twitter: https://twitter.com/lexfridman – Instagram: https://www.instagram.com/lexfridman – LinkedIn: https://www.linkedin.com/in/lexfridman – Facebook: https://www.facebook.com/lexfridman – Medium: https://medium.com/@lexfridman OUTLINE: Here’s the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. (00:00) – Introduction (06:34) – World hunger (12:37) – Hunger Ward (35:04) – Language (40:15) – Famine (50:59) – Authoritarianism (57:27) – Storytelling (1:11:01) – Access (1:15:24) – Trust (1:19:06) – Film equipment (1:23:52) – Editing (1:30:21) – Filmmaking (1:43:20) – Favorite Films (1:54:28) – Lifeboat (2:01:53) – Breaking rules (2:04:48) – Fear (2:08:27) – 50 feet from Syria (2:13:24) – Money and distribution (2:21:02) – Advice for young people (2:24:07) – Books (2:26:01) – Darkest moments (2:30:32) – Meaning of life (2:32:30) – Mortality

Andrew Huberman is a neuroscientist at Stanford and host of the Huberman Lab Podcast. Please support this podcast by checking out our sponsors: – Brave: https://brave.com/lex – LMNT: https://drinkLMNT.com/lex to get free sample pack – ROKA: https://roka.com/ and use code LEX to get 20% off your first order – Indeed: https://indeed.com/lex to get $75 credit – MasterClass: https://masterclass.com/lex to get 15% off EPISODE LINKS: Andrew’s YouTube: https://youtube.com/AndrewHubermanLab Huberman Lab Podcast: https://hubermanlab.com Andrew’s Twitter: https://twitter.com/hubermanlab Andrew’s Instagram: https://instagram.com/hubermanlab PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: – Check out the sponsors above, it’s the best way to support this podcast – Support on Patreon: https://www.patreon.com/lexfridman – Twitter: https://twitter.com/lexfridman – Instagram: https://www.instagram.com/lexfridman – LinkedIn: https://www.linkedin.com/in/lexfridman – Facebook: https://www.facebook.com/lexfridman – Medium: https://medium.com/@lexfridman OUTLINE: Here’s the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. (00:00) – Introduction (07:25) – Diet (17:30) – Attribution in science (20:11) – Rick Rubin (27:57) – Mental states (42:38) – Controversial guests (55:19) – Karl Deisseroth (59:34) – Difficult conversations (1:06:36) – Big guests (1:20:22) – Academia (1:27:23) – Freedom of speech (1:38:26) – If by Rudyard Kipling (1:45:37) – Music (1:51:16) – Public speaking (2:10:11) – Non-sleep deep rest (2:24:32) – Focus (2:34:52) – Stress and anxiety (2:54:48) – Sauna (3:06:14) – Sex (3:14:07) – Love and relationships

Michael Saylor is the CEO of MicroStrategy and a prominent holder and proponent of Bitcoin. Please support this podcast by checking out our sponsors: – Scale: https://scale.com/lex – Coinbase: https://coinbase.com/lex to get $10 in free Bitcoin – Audible: https://audible.com/lex to get $9.95 a month for 6 months – NetSuite: http://netsuite.com/lex to get free product tour – SimpliSafe: https://simplisafe.com/lex and use code LEX EPISODE LINKS: Michael’s Twitter: https://twitter.com/saylor MicroStrategy: https://microstrategy.com/ Michael’s Book: https://amzn.to/37J2iA0 Book mentioned: https://amzn.to/3jwsIaP PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: – Check out the sponsors above, it’s the best way to support this podcast – Support on Patreon: https://www.patreon.com/lexfridman – Twitter: https://twitter.com/lexfridman – Instagram: https://www.instagram.com/lexfridman – LinkedIn: https://www.linkedin.com/in/lexfridman – Facebook: https://www.facebook.com/lexfridman – Medium: https://medium.com/@lexfridman OUTLINE: Here’s the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. (00:00) – Introduction (07:09) – Grading our understanding (19:27) – Inflation (39:03) – Government (1:00:13) – War and power (1:11:23) – Dematerializing information (1:42:45) – Digital energy and assets (1:54:23) – Oil barrel vs Bitcoin (2:03:43) – Layers of Bitcoin (2:20:53) – Bitcoin’s role during wartime (2:25:37) – Jack Dorsey (2:41:58) – Bitcoin conflict of interest (2:48:39) – Satoshi Nakamoto (2:54:04) – Volatility (3:06:30) – Bitcoin price (3:18:46) – Twitter verification (3:27:42) – Second best crypto (3:33:24) – Dogecoin (3:37:57) – Elon Musk (3:43:26) – Advice for young people (3:54:54) – Mortality (3:57:59) – Meaning of life

Rick Rubin is one of the greatest music producers of all time, working with many of the greats including Beastie Boys, Eminem, Metallica, LL Cool J, Kanye West, Slayer, Tom Petty, Johnny Cash, Dixie Chicks, Aerosmith, Adele, Danzig, Red Hot Chili Peppers, System of a Down, Jay-Z, Black Sabbath. Please support this podcast by checking out our sponsors: – Lambda: https://lambdalabs.com/lex – Theragun: https://therabody.com/lex to get 30 day trial – ROKA: https://roka.com/ and use code LEX to get 20% off your first order – Onnit: https://lexfridman.com/onnit to get up to 10% off – ExpressVPN: https://expressvpn.com/lexpod and use code LexPod to get 3 months free EPISODE LINKS: Rick’s Twitter: https://twitter.com/RickRubin Broken Record Podcast: https://bit.ly/3j7BFXZ PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: – Check out the sponsors above, it’s the best way to support this podcast – Support on Patreon: https://www.patreon.com/lexfridman – Twitter: https://twitter.com/lexfridman – Instagram: https://www.instagram.com/lexfridman – LinkedIn: https://www.linkedin.com/in/lexfridman – Facebook: https://www.facebook.com/lexfridman – Medium: https://medium.com/@lexfridman OUTLINE: Here’s the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. (00:00) – Introduction (07:46) – Nietzsche and music (18:47) – Rick’s approach with artists (30:10) – Beautiful simplicity in music (33:54) – Marvin Gaye (43:09) – Best album of all time (47:02) – Paul McCartney (49:08) – Ideas (51:30) – Rebellion and conformity (56:18) – Fitness (59:27) – Johnny Cash (1:09:23) – Tom Waits (1:14:01) – Lyrics vs rhythm (1:18:48) – Johnny Cash continued (1:20:47) – Beastie Boys (1:27:09) – Depression (1:31:31) – Art vs Business (1:40:18) – Art of conversation (1:56:52) – Rick’s podcast (2:00:02) – Advice for young people (2:04:07) – Mortality (2:06:42) – Meaning of life

Karl Deisseroth is a professor of bioengineering, psychiatry, and behavioral sciences at Stanford University. Please support this podcast by checking out our sponsors: – BiOptimizers: http://www.magbreakthrough.com/lex to get 10% off – BetterHelp: https://betterhelp.com/lex to get 10% off – Notion: https://notion.com/startups to get up to $1000 off team plan – Blinkist: https://blinkist.com/lex and use code LEX to get 25% off premium – Magic Spoon: https://magicspoon.com/lex and use code LEX to get $5 off EPISODE LINKS: Karl’s Twitter: https://twitter.com/karldeisseroth Karl’s Website: https://web.stanford.edu/group/dlab Projections (book): https://amzn.to/3NKmdiJ PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: – Check out the sponsors above, it’s the best way to support this podcast – Support on Patreon: https://www.patreon.com/lexfridman – Twitter: https://twitter.com/lexfridman – Instagram: https://www.instagram.com/lexfridman – LinkedIn: https://www.linkedin.com/in/lexfridman – Facebook: https://www.facebook.com/lexfridman – Medium: https://medium.com/@lexfridman OUTLINE: Here’s the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. (00:00) – Introduction (06:58) – Mental disorders (15:31) – Intelligence (18:10) – James Joyce (26:47) – Writing (30:11) – Projections (33:46) – Translation (36:17) – Poetry (45:00) – Love (50:34) – Psychiatry (53:46) – Sigmund Freud and Carl Jung (1:02:30) – Data in cells (1:06:33) – Optogenetics (1:22:01) – Neuralink (1:34:49) – Psychedelics (1:41:13) – Depression (1:56:38) – Talk therapy and psychoanalysis (2:00:19) – Good Will Hunting (2:10:55) – Darkest moments (2:12:26) – Suicide (2:29:31) – Autism (2:49:09) – Schizophrenia (3:00:18) – Why we cry (3:07:30) – Consciousness (3:22:01) – Mortality (3:23:41) – Meaning of life