NASA engineer Dr Ashitey Trebi-Ollennu discusses the meaning of his work designing robots, including the Mars Rover.

Professor Nazneen Rahman, one of the world's leading cancer geneticists, talks about the latests developments in her work.

Moshe Safdie, a renowned architect and theorist, reflects on his transformative journey from kibbutz life to designing iconic structures like Habitat 67. He discusses the balance between aesthetic appeal and social responsibilities in contentious areas, particularly in Jerusalem. Safdie highlights the importance of community engagement and cultural sensitivity in architecture, revealing how these principles shaped projects like the Nakba and Sikh museums. He also critiques the evolution of architectural philosophies, advocating for designs that are not only beautiful but resonate with local identities.

How second cities around the world can find a new shape and Houben's focus on transport patterns and the way people use public space. Recorded in partnership with RIBA.

The Olympic Cauldron designer Thomas Heatherwick talks about the importance of 'making', getting your hands dirty and asking the right questions when designing a project. Recorded in partnership with RIBA.

David Adjaye has been described as an architect with an 'artist's sensibility'. His internationally renowned buildings are defined by his bold use of innovative materials, and imbued with the stories of people and dynamics of place. In this programme, recorded in partnership with RIBA, David Adjaye talks to Razia Iqbal about his approach to building, his many journeys and the projects and experiences that have defined him.

The Psychiatrist Kay Redfield Jamison is a world leading specialist in bipolar disorder, and suffers from the condition herself. She shares her unique perspective with A.C.Grayling and an audience at Wellcome Collection, London.

Why do locusts swarm? How do ants manage their traffic flow so much better than humans? Iain Couzin talks to Matthew Sweet about what we can learn from collective animal behaviour.

Henry Markram has received the biggest personal grant in the history of science. He has a billion euros to build a super computer which will replicate the human brain. He tells A.C.Grayling and an audience at Wellcome Collection how the virtual brain will reveal revolutionise the treatment of mental disorders.

Molecular biologist Bonnie Bassler, a world specialist in how bacteria communicate within the human body, discusses the key to solving the antibiotic problem and her groundbreaking discoveries in bacterial communication. Topics covered include the fascinating world of bacteria, their roles in our bodies, the concept of quorum sensing in bacterial communication, challenges posed by harmful bacteria and antibiotic resistance, and potential alternative strategies for treating bacterial infections.