All-In with Chamath, Jason, Sacks & Friedberg

In a lively discussion, Dave Ricks, CEO of Eli Lilly, shares insights from his leadership in developing GLP-1 medicines, including tirzepatide. He dives into the significant impact of these drugs on weight loss and unexpected benefits for addiction and mental health. Ricks addresses the challenges of counterfeit products, pricing dynamics, and the biotech funding landscape. He also explores the future of pharma breakthroughs, highlighting brain diseases as the next frontier, while advocating for better public health policies and patient empowerment through AI.

The hosts explore the controversial $100K H-1B fee proposal and its implications for the job market. They dive into alarming research linking prenatal acetaminophen use to autism risk, discussing diagnosis and potential treatments. Jimmy Kimmel's return prompts a heated debate over his apology and media narratives following recent political events. Additionally, they unpack significant AI advancements and YouTube's admission of past censorship, raising questions about new hate speech laws in California.

Eric Schmidt, the former Google Executive Chairman, dives deep into AI, defense tech, and the U.S.-China rivalry. He argues for the importance of in-person work, highlighting how it fosters mentorship and competes with China’s work ethic. Schmidt examines China's aggressive AI strategy, contrasts open source models with their closed counterparts, and discusses the rise of automation in warfare. He also addresses America’s demographic challenges and the role of immigration in maintaining strength, along with insights on the future of AGI.

The hosts tackle the fallout from Charlie Kirk's death, exploring how isolation and online radicalization can fuel political violence. They also discuss Jimmy Kimmel's indefinite suspension from ABC, highlighting the clash between free speech and cancel culture. The podcast delves into the ambitious media moves of the Ellison family, including TikTok divestiture, while reflecting on the implications for the industry. Lastly, there's a humorous take on YouTube's algorithmic moderation impacting their own content.

Anatoly Yakovenko, the co-founder and CEO of Solana Labs, dives into the transformative power of cryptocurrency. He discusses the potential of stablecoins and the impact of regulatory shifts on the market. Yakovenko highlights exciting sectors beyond finance, such as social media and real estate, that could benefit from blockchain. He also explores the implications of quantum computing and AI on the crypto landscape, while addressing Bitcoin's resilience and Ethereum's evolving role in payments. A thought-provoking conversation on the future of money!

Dara Khosrowshahi, CEO of Uber and a leader in the company's push into autonomy and innovative transportation, shares insights on the future of self-driving technology. He discusses the diverse partnerships fueling Uber's self-driving ambitions and safety evaluations comparing various approaches like LiDAR and computer vision. Dara reveals how Robo-taxis could reshape Uber's business model and improve marketplace economics. He also addresses the potential job displacement fears and outlines Uber's vision for future mobility, including drones and eVTOLs.

Sian Beilock, President of Dartmouth College and expert on performance under stress, joins Rich Lyons, Chancellor of Berkeley and an economist, to discuss the current state of US universities. They tackle the heavy burden of student loans and the implications of rising unemployment among graduates. The duo also addresses the impact of administrative bloat, diversity initiatives, and the shifting dynamics of K-12 education on higher education. They ponder whether AI learning will disrupt traditional pathways and emphasize the need for viewpoint diversity on campuses.

Tulsi Gabbard, former Democratic congresswoman from Hawaii and current US Director of National Intelligence, dives into the controversies surrounding the Russiagate hoax and the dangers of politicized intelligence agencies. She discusses the importance of accountability and transparency within these agencies and shares her experiences after switching parties. Gabbard also touches on U.S. foreign policy, particularly regarding military decisions about Iran, and examines the complex dynamics of drug cartels and their designation as terrorist organizations.

Vlad Tenev, Co-founder and CEO of Robinhood, discusses the revolutionary potential of tokenizing stocks, including shares in companies like OpenAI and SpaceX. He shares insights on the shifting political landscape and how it affects financial regulation and investor access. Tenev also highlights the importance of educating young investors about financial tools and risks. Additionally, they explore the role of mathematical superintelligence in fintech, aimed at enhancing AI capabilities to improve user engagement and product offerings.

In this discussion, Demis Hassabis, the Co-founder and CEO of DeepMind, shares insights on AI and creativity, reflecting on his Nobel Prize achievements. He explains DeepMind's role within Alphabet and its revolutionary models like AlphaFold and Genie. The conversation highlights the democratization of creativity through tools like the Nano Banana image generator. Hassabis also emphasizes the future of scientific breakthroughs, merging AI with drug discovery, and creating immersive storytelling experiences, paving the way for a golden age of science.