NB Hot Topics Podcast

Welcome to the latest episode of the Hot Topics Podcast with Neal Tucker from NB Medical.All about coronavirus again! The two big topics this week are immunity and the importance of T cells plus an in-depth look at post-COVID syndrome, how we can anticipate the effects on the population and the resources that can help us manage it.We've also got research on remdesivir and more on how SARS-CoV-2 affects children, plus why COVID-19 isn't a lifestyle disease but lifestyle medicine still has a role in general practice.References:Moving Medicine evidence reviewNHS After-care needs of inpatients recovering from COVID-19Royal Society of Occupational Therapists Fatigue Management GuideHomerton University Hospitals Post-COVID Patient PackNEJM Remdesivir RCTNEJM Children & COVID 19 Italy LetterJAMA Persistent Symptoms after Acute COVIDwww.nbmedical.com/podcast

In our latest Hot Topics podcast, Neal Tucker discusses the latest news and research for primary care. This week a firm focus on coronavirus once again. We talk about antibody tests and why there seems such discrepancies between the real world results in you and I and the tests' supposed accuracy. We talk about dexamethasone and the implications for primary care. And we discuss the possibility of a 2nd wave of coronavirus, how this will our jobs in primary care and what we can do to keep ourselves happy.ReferencesSt George's Antibody Data Recovery Trial Dexamethasone Results Lancet Report in Iran's 2nd wave www.nbmedical.com/podcast

In the latest episode of the Hot Topics Podcast, Neal Tucker discusses the latest news and research relevant to primary care.Today we talk about race, inequalities and unconscious bias and how this affects decisions about BAME medics in the UK. We also look at a Lancet paper on hydroxychloroquine risks which has been retracted due to suspicious reporting of data, and the 'tsunami' of mental illness anticipated due to coronavirus.In new research we discuss government recommendations on face masks for the public in light of a new systematic review published in the Lancet on reducing the spread of SARS-CoV-2, use of the NEWS score in primary care and liraglutide as a weight-loss treatment for childhood obesity.Don't forget to join us for our free Hot Topics Mental Health and COVID-19 webinar. Sign up at: https://bit.ly/NBMedicalCOVIDMentalHealthLinks:BJGP Protecting Health of Doctors https://bjgp.org/content/70/695/268Lancer Retraction of Hydroxychloroquine Paper https://www.thelancet.com/lancet/article/S0140673620313246Lancet Prevent of spread of SARS-CoV-2 https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)31142-9/fulltextRCPsych Report on mental illness and Covid 19 https://www.rcpsych.ac.uk/news-and-features/latest-news/detail/2020/05/15/psychiatrists-see-alarming-rise-in-patients-needing-urgent-and-emergency-careMIND Coronavirus resources https://www.mind.org.uk/information-support/coronavirus/NEJM Liraglutide in adolescents study https://www.nejm.org/doi/full/10.1056/NEJMoa1916038?query=featured_homewww.nbmedical.com/podcast

In this latest Hot Topics Podcast, Neal Tucker reviews the latest knowledge about coronavirus and non-SARs-CoV2 research relevant to primary care.We review new reports of Kawasaki-like disease in children with Covid-19 and the implications for children returning to school. We examine data on hydroxychloroquine and azithromycin suggesting it may kill more than it cures. And we have a think about testing and the new antibody tools.In non-coronavirus research, we look at SGLT2i and renal disease, P2Y12 inhibitors and CVD secondary prevent, whether GPs are successful in helping patients with weight loss and gestational diabetes.ReferencesKawasaki-like Disease in Children with Covid-19 https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)31103-X/fulltextHydroxychloroquine for Covid-19 https://www.bmj.com/content/369/bmj.m1361Hydroxychloroquine + azithromycin https://jamanetwork.com/journals/jama/fullarticle/2766117Lopinavir Ritonavir in Covid-19 https://www.nejm.org/doi/full/10.1056/NEJMoa2001282?query=featured_homeBCG vaccination and Covid rates https://jamanetwork.com/journals/jama/fullarticle/2766182?guestAccessKey=a37db46c-11e4-4243-b878-648c9bf2631a&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=051320Interpreting Test Results https://www.bmj.com/content/369/bmj.m1808SGLT2i and renal disease https://www.bmj.com/content/369/bmj.m1186P2Y12 inhibitors and CVD https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)30315-9/fulltextGestational Diabetes progression https://www.bmj.com/content/369/bmj.m1361Paid for weight loss programme referrals from GP https://bjgp.org/content/70/694/e348www.nbmedical.com/podcast

In our latest Hot Topics podcast Neal Tucker examines the emerging treatments for Covid-19 including remdesivir, antiplatelets, vitamin D and vaccinations. Do these provide the magic bullet we need to shut down the infection and open up the world?He also reviews the latest research including data on asymptomatic and pre-symptomatic disease in children, important for when schools re-open, and the elderly, important for managing Covid-19 in care homes. He also looks at some emerging data on the extra-respiratory effects of the disease and how it may present in primary care.References:Children and covid: www.jamanetwork.com/journals/jamapediatrics/fullarticle/2764394Children as vectors: www.thelancet.com/journals/laninf/article/PIIS1473-3099%2820%2930236-X/fulltextRisk to children BMJ Editorial: https://www.bmj.com/content/369/bmj.m1669Care Home Transmission NEJM: https://www.nejm.org/doi/full/10.1056/NEJMoa2008457?query=featured_homeJAMA Homeless Shelter: https://jamanetwork.com/journals/jama/fullarticle/2765378Remdesivir https://www.bbc.co.uk/news/health-52478783Antiplatelets: https://www.sciencedirect.com/science/article/pii/S2211383520305529ACEi/ARB benefit: https://www.ahajournals.org/doi/10.1161/CIRCRESAHA.120.317134New Scientiest 4 Coronaviruses: https://www.newscientist.com/article/mg24632800-700-what-four-coronaviruses-from-history-can-tell-us-about-covid-19/www.nbmedical.com/podcast

In this latest coronavirus special Neal Tucker discusses the latest knowledge about COVID-19 and how general practice will need to adapt to a world with persisting coronavirus.We discuss the effects of coronavirus on black, Asian and minority ethnic populations, new understanding about the clinical features of COVID-19 especially in cardiac disease, how facemasks can help protect us by limiting the spread from others and how the infection is affecting care homes.In our in-depth section we think about how general practice might need to adapt for a future with coronavirus, what barriers we face and how this could be an opportunity to re-design primary care for the benefit of patients and staff alike.COVID 19 and African Americans www.jamanetwork.com/journals/jama/fullarticle/2764789European Society of Cardiology Myosytis www.youtube.com/embed/3qINtzH2PfI?rel=0&autoplay=1BMJ Facemasks www.bmj.com/content/369/bmj.m1435 T Greenhalgh, J Howard www.fast.ai/2020/04/13/masks-summary/www.nbmedical.com/podcast

The latest NB Hot Topics podcast is the third Coronavirus Special: Saving Lives and the End of Life.In this edition, Neal Tucker reviews what we have learned about coronavirus this week including the clinical features which you have been reporting, anosmia as a marker of COVID-19, the controversy around the Roth test and how viral load relates to the severity of disease.In the second part, we have an in-depth look at end of life care in the community for patients with COVID-19 including helpful alternatives to syringe drivers or subcut injections.www.nbmedical.com/podcast

In this week's NB Hot Topics Podcast Neal Tucker looks at the latest developments in the coronavirus literature including data on hydroxychloroquine/azithromycin combination treatment, why lockdown alone is not enough and why coronavirus modelling won't help us.Now that general practice is moving from the preparation phase to managing COVID-19 in the community, we focus on the clinical presentation of the disease in our patients and colleagues, and how our experiences show it differs from hospital data and published guidance. In light of these uncertainties, what are our options? www.nbmedical.com/podcast

In this week's NB Hot Topics Podcast, Neal Tucker looks at what lessons we can learn in general practice to help us prepare for and fight the coronavirus pandemic.We can learn from our international colleagues who are ahead of us on the curve, and we speak to Dr Nadege Fancy, a GP in Milan, northern Italy, about what we can expect over the next few weeks.We share how practices are adapting to meet the needs of our patients as the pandemic escalates in the UK. We review what new data we know about COVID-19 and explore issues around NSAIDs, ACEi/ARBs, hydroxychloroquine and testing. Finally, we remind us to look after ourselves. In this marathon, we need to make time for ourselves if we are to continue to look after our patients.www.nbmedical.com/podcast

With all the stress and uncertainty Coronavirus has placed on the world and the health service this special podcast Dr Neal Tucker looks how we as professionals and humans are coping with COVID-19, what we need to know from the rapid changes in guidance over the past few days, and where we may be going next.In the second half we look at what the latest science tells us about Coronavirus, how it might affect our patients and what we can do to help them and ourselves.One thing is for certain, general practice is the most adaptable branch of medicine, we have fantastic teams and camaraderie, we thrive in resource-poor settings and at managing huge uncertainty on a daily basis. We can get through this together.www.nbmedical.com/podcast