

The TWIML AI Podcast (formerly This Week in Machine Learning & Artificial Intelligence)
Sam Charrington
Machine learning and artificial intelligence are dramatically changing the way businesses operate and people live. The TWIML AI Podcast brings the top minds and ideas from the world of ML and AI to a broad and influential community of ML/AI researchers, data scientists, engineers and tech-savvy business and IT leaders. Hosted by Sam Charrington, a sought after industry analyst, speaker, commentator and thought leader. Technologies covered include machine learning, artificial intelligence, deep learning, natural language processing, neural networks, analytics, computer science, data science and more.
Episodes
Mentioned books

114 snips
Aug 19, 2025 • 1h 1min
Genie 3: A New Frontier for World Models with Jack Parker-Holder and Shlomi Fruchter - #743
In this engaging discussion, Jack Parker-Holder and Shlomi Fruchter, both researchers at Google DeepMind, dive into Genie 3, a groundbreaking model that creates playable virtual worlds. They explore the evolution of world models in AI, emphasizing their importance for decision-making and planning. The duo sheds light on Genie 3’s real-time interactivity, visual memory capabilities, and the challenges faced in its development. They also touch on the innovative concept of promptability, showcasing how the model can dynamically manipulate virtual environments, paving the way for exciting applications.

54 snips
Aug 12, 2025 • 1h 1min
Closing the Loop Between AI Training and Inference with Lin Qiao - #742
Lin Qiao, CEO and co-founder of Fireworks AI and former AI leader at Meta, shares insights on optimizing the AI development lifecycle. She emphasizes the importance of aligning training and inference systems to minimize deployment friction. Lin discusses the shift from viewing models as commodities to essential product assets and explains reinforcement fine-tuning for leveraging proprietary data. She also tackles the complex challenge of balancing cost, latency, and quality in AI optimization while envisioning a future with closed-loop systems for automated model improvement.

286 snips
Jul 29, 2025 • 46min
Context Engineering for Productive AI Agents with Filip Kozera - #741
Filip Kozera, Founder and CEO of Wordware, is on a mission to revolutionize how we interact with AI through natural language as the new programming interface. He discusses the architecture of AI agents, emphasizing the need for 'graceful recovery' systems that involve humans when agents hit knowledge limits. The conversation explores the shift to user-centric workflows and the challenges of data silos in SaaS platforms. Filip's vision for the 'word artisan' potentially transforms non-technical users into AI managers, reshaping knowledge work.

59 snips
Jul 22, 2025 • 1h 13min
Infrastructure Scaling and Compound AI Systems with Jared Quincy Davis - #740
Jared Quincy Davis, Founder and CEO at Foundry and a former DeepMind core deep learning team member, discusses transformative 'compound AI systems' that merge diverse AI models for superior performance. He introduces 'laconic decoding' and explains how these systems can boost efficiency while cutting costs. The conversation covers the interplay between AI algorithms and cloud infrastructure, the evolution of ensemble models, and the potential of hybrid systems. Davis emphasizes co-design and innovative strategies to revolutionize the AI landscape and enhance developer experience.

163 snips
Jul 15, 2025 • 1h 13min
Building Voice AI Agents That Don’t Suck with Kwindla Kramer - #739
Kwindla Kramer, co-founder and CEO of Daily, shares his insights on building real-time conversational voice AI. He discusses the full stack of voice agents, emphasizing the importance of a modular approach for better latency and cost-efficiency. Kwindla delves into challenges like interruption handling and natural dialogue dynamics. He also highlights the future of voice AI in use cases, hybrid edge-cloud pipelines, and exciting advancements like real-time video avatars. It's a comprehensive look at the dynamic world of voice technology!

70 snips
Jul 9, 2025 • 1h
Distilling Transformers and Diffusion Models for Robust Edge Use Cases with Fatih Porikli - #738
In this conversation with Fatih Porikli, Senior Director of Technology at Qualcomm AI Research, he unveils cutting-edge innovations from the CVPR conference. He discusses DiMA, a groundbreaking system using large language models for safe autonomous driving, dramatically reducing collision rates. Fatih also dives into SharpDepth, enhancing depth prediction through diffusion distillation. He highlights impressive on-device demos, from text-to-3D mesh generation to real-time video fabrication, showcasing the future of AI and computer vision.

195 snips
Jun 24, 2025 • 56min
Building the Internet of Agents with Vijoy Pandey - #737
Vijoy Pandey, SVP at Outshift by Cisco, shares insights on creating the "Internet of Agents" to improve collaboration among diverse agent systems from vendors like Salesforce and Microsoft. He discusses the challenges of integrating these systems and introduces AGNTCY, an open-source project aimed at enhancing interoperability. Vijoy breaks down the four phases of agent collaboration and reveals SLIM, a new transport layer ensuring secure, real-time communication. The conversation sheds light on overcoming semantic challenges and the importance of evolving communication protocols in AI.

91 snips
Jun 17, 2025 • 60min
LLMs for Equities Feature Forecasting at Two Sigma with Ben Wellington - #736
In this enlightening discussion, Ben Wellington, Deputy Head of Feature Forecasting at Two Sigma, shares his expertise in AI-driven equity feature forecasting. He delves into the intricacies of identifying and quantifying measurable features to improve predictive accuracy. The use of satellite imagery for data points like vehicle counts unveils unique insights. Ben emphasizes the importance of strict data timestamping to avoid temporal leakage and discusses the transformative role of large language models in enhancing data analysis. He also offers a glimpse into the future of agentic AI in finance.

165 snips
Jun 10, 2025 • 57min
Zero-Shot Auto-Labeling: The End of Annotation for Computer Vision with Jason Corso - #735
Join Jason Corso, co-founder of Voxel51 and University of Michigan professor, as he unpacks the fascinating world of automated labeling in computer vision. Discover FiftyOne, a tool for visualizing datasets and enhancing data quality. Jason reveals how zero-shot auto-labeling can rival human performance, offering significant efficiency gains. He also dives into the challenges of label quality, decision boundaries, and the innovative 'verified auto-labeling' method. Plus, learn about synthetic data generation and the exciting future of agentic behaviors in AI!

226 snips
Jun 5, 2025 • 1h 25min
Grokking, Generalization Collapse, and the Dynamics of Training Deep Neural Networks with Charles Martin - #734
In this insightful conversation, Charles Martin, the founder of Calculation Consulting and an AI researcher merging physics with machine learning, introduces WeightWatcher, a groundbreaking tool for enhancing Deep Neural Networks. He explores the revolutionary Heavy-Tailed Self-Regularization theory and how it exposes phases like grokking and generalization collapse. The discussion delves into fine-tuning models, the perplexing relationship between model quality and hallucinations, and the challenges of generative AI, providing valuable lessons for real-world applications.