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a16z Live

Latest episodes

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Sep 28, 2021 • 14min

One on One with A and Z #11: How much rare knowledge is there?

This is an excerpt from the a16z Clubhouse show One on One with A and Z, where a16z cofounders Marc Andreessen and Ben Horowitz answer questions on tech trends, company building, and more. To catch full live episodes of the show, follow the a16z Club on Clubhouse. 
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6 snips
Sep 8, 2021 • 52min

Good Time Show: What It Takes to Survive with Lyft Founder John Zimmer

The early days of Zimrides [2:08]Driving early virality [7:56]Competing with Uber [15:47]Why they took political stances [27:03]Managing through the pandemic [38:09]The future focus for Lyft -- autonomous vehicles and the end of car ownership [42:50]Follow the a16z Club to join conversations with tech founders, builders, and leaders live and in-full.
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Sep 3, 2021 • 52min

a16z Bio + Health #18: What will it take to cure diabetes?

An overview of diabetes Type 1 and Type 2 [2:58]Thinking beyond Type 1 and Type 2 [6:58]New treatment options: stem cells, continuous glucose monitoring [14:19]What's the timeline on stem cell therapies? [17:15]Therapies for controlling, rather than curing, diabetes [23:52]The current technology challenges to treating diabetes [29:52]The challenges in education and access [35:41]This is an excerpt from the a16z Bio show on Clubhouse, where we explore all the ways that biology is technology. To catch full episodes of the show, follow the a16z Club on Clubhouse.
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Aug 31, 2021 • 44min

a16z Bio + Health #17: Proteomics and Product around a Technological Breakthrough

Founding story of Nautilus [1:43]Why was the Nautilus approach to proteomics a breakthrough? [6:12]Why a startup instead of academic research? [9:57]How to pick a good cofounder (it's not that different from choosing a spouse) [15:32]Advice for academic founders: how to work with VCs  [21:14]The tipping points of scale & the challenges of finding good talent  [25:17]Is proteomics really a gamechanger? [30:49]How is Nautilus bringing it to market? [34:17]What Nautilus can learn from Illumina and genomics [37:32]Looking ahead to the next 10 years [41:26]This is an excerpt from the a16z Bio show on Clubhouse, where we explore all the ways that biology is technology. To catch full episodes of the show, follow the a16z Club on Clubhouse.
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Aug 25, 2021 • 19min

One on One with A and Z #10: The Impact of System Design on Culture

This is an excerpt from the a16z Clubhouse show One on One with A and Z, where a16z cofounders Marc Andreessen and Ben Horowitz answer questions on tech trends, company building, and more live . To catch full episodes of the show, follow the a16z Club on Clubhouse.  
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Aug 23, 2021 • 57min

Capital Markets #1 with MSCI CEO Henry Fernandez: What goes into an index?

The MSCI origin story [1:07]How does an index get constructed? [6:51]How do you keep an index accurate? [11:42]MSCI business model... how do they get paid? [16:27]MSCI, competition, and why not an open source index? [23:14]ESG and investment objectives [27:00]ESG disclosure frameworks and the role of government in ESG [32:50]Defining ESG [34:44]MSCI, crypto, and other asset classes [42:55]Why an index business instead of principal investing? [51:09]Follow the a16z Club to join conversations with tech founders, builders, and leaders live and in-full.
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Aug 18, 2021 • 60min

Good Time Show: Metaverse + Crypto

SPEAKERS:Aarthi Ramamurthy, international, ClubhouseDonnie Dinch, founder and CEO, BitskiGabby Dizon, cofounder, Yield Guild GamesJarrod Dicker, operating partner, TCGJesse Walden, founder, Variant FundJon Lai, principal, a16zPacky McCormick, founder, Not BoringSriram Krishnan, general partner, a16zTwobadour, founder, MetapurseJustin “3LAU” Blau, producer and musicianoriginally aired on Clubhouse  https://twitter.com/sriramk/status/1422987628958208007
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Jul 27, 2021 • 59min

a16z Infra #6: The Cost of Cloud vs. Repatriation

This conversation centers on the arguments and findings of the a16z piece The Cost of Cloud, a Trillion Dollar Paradox. The Core Findings of The Cost of Cloud piece [5:22]Cloud is a significant part of COGS for public SaaS companies [8:38]Should you allocate engineers to reduce cloud cost or just focus on growth? [12:06]How much of a problem is not knowing cloud spend? [15:56]The tradeoff between focusing cost and engineering resources [19:33]Should large public SaaS companies repatriate? [23:41]Performance  matters -- it's not all about cost [31:55]Is all the talent for running data centers at the Google, AWS, and Azure? [37:46]Will the cloud feature set become commoditized? [44:57]Cloud oligopoly and market dynamics [50:39]Follow the a16z Club to join conversations with tech founders, builders, and leaders live and in-full.
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Jul 19, 2021 • 52min

Good Time Show: a16z's Journey with Crypto and Crypto Investing

This podcast is an excerpt. Follow the a16z Club to join conversations with tech founders, builders, and leaders live and in-full.Early days of a16z crypto [2:38]New crypto governance capabilities [16:34]How is the VC model different when investing in crypto? [22:24]Crypto regulation and the recent attempt at holiday rulemaking [29:49]Is anyone effectively regulating crypto? [34:15]How do you start working in crypto? [36:58]What problems should crypto founders work on? [43:51]Identity, crypto, and the future of social networks [45:15]Centralized vs. decentralized: the battle for the internet [48:17]
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Jul 16, 2021 • 50min

a16z Infra #5: Category Creation with Armon Dadger (HashiCorp) and Stephen Mullaney (Aviatrix)

What makes a category? [0:37]The leading indicator? Everyone thinks you're crazy. [5:36]Can you create a category whole cloth? [7:02]How to create a category [12:05]The best category creation CEOs are product marketers [15:55]Category creation tactics: certification programs [18:54]Category creation tactics: persona-based storytelling [22:17]Is there a repeatable way to make a category? [25:35]The role of the CTO and product teams in creating the message [29:22]How do you structure product marketing? [45:16]This is an excerpt from the a16z Clubhouse show a16z Infra. To catch full episodes of the show, follow the a16z Club on Clubhouse. 

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