Desert Island Discs

Kirsty Young's castaway this week is the scientist Professor Kay Davies. She has dedicated much of her life to finding a cure for the severest form of muscular dystrophy. Before she was 40, she had helped to develop the antenatal test which is now used around the world, then she isolated the gene sequence which could be instrumental in treating the condition. After years spent working on that, human trials for a possible treatment are about to begin.It's quite something for a woman who doesn't have an O-level in biology. Although, even as a child she did possess that critical quality crucial to scientific pioneers: "I loved solving problems," she says, "I was very tenacious and would sit in my room until I had finished the problem. I am a sticker."[Taken from the original programme material for this archive edition of Desert Island Discs]Favourite track: Piano Sonata in B Flat by Franz Schubert Book: Untold Stories by Alan Bennett Luxury: A piano.

Kirsty Young's castaway this week is the actor David Suchet. He has won armfuls of awards for his work - most recently an Emmy for his portrayal of Robert Maxwell - but he is best known for the character he has been associated with for 20 years, Hercule Poirot.His approach to his work is meticulous and he says he has to inhabit each role he takes on. In this illuminating interview he recalls how, early in his career, a psychologist showed him how to shed his character at the end of each performance otherwise, he found, the edges between his own life and those of the person he was playing became blurred.[Taken from the original programme material for this archive edition of Desert Island Discs]Favourite track: When I Fall In Love by Nat King Cole Book: Magnum Magnum by Brigitte Lardinois Luxury: His clarinet and an unlimited supply of reeds.

Kirsty Young's castaway this week is the bass-baritone Thomas Quasthoff. He has performed in concert halls the world over under the batons of the finest conductors and, while he made his name as a Lieder singer, he's equally popular for his jazz, spiritual and gospel recordings. Music critics say he is "one of the great singers of our time and one of the most remarkable of any time." That his life has been remarkable is a reference to his disability: he was born suffering the effects of Thalidomide and although his early musical talent was spotted, his inability to play the piano meant he was not allowed to take up a place at a conservatoire.In this candid and moving interview, though, he describes how, with his family's support, he went on to build a highly successful career. Now, living contentedly with his wife and daughter, he says his life is a full and satisfying one. He adds that when he sees how readily people become consumed by envy and resentment, he questions whether that too isn't a kind of disability.[Taken from the original programme material for this archive edition of Desert Island Discs]Favourite track: The Adagietto from 5th symphony by Gustav Mahler Book: Long Walk to Freedom by Nelson Mandela Luxury: Good wine.

Kirsty Young's castaway this week is the writer Alan Sillitoe. 50 years ago his debut novel Saturday Night and Sunday Morning captured the truth and brutality of post war working class life. It was a world he knew intimately - he grew up in the tight, terraced streets of Nottingham and, from a very young age, harboured an ambition to escape. As a child, he read voraciously and knew he wanted to explore the world. During the war he was a navigator in Malaya but, when he returned to Britain, he was shocked to be told he had contracted tuberculosis. As he convalesced in hospital he started writing and, once he had been discharged, his disability pension gave him the security to sustain him while he pursued his career. When Saturday Night and Sunday Morning was published, critics said his was a more authentic voice than D H Lawrence's. But the extraordinary reviews made scant impact on Alan Sillitoe - he says he had developed a healthy scorn for the opinions of critics - but he remains grateful, he says, to the book that brought him security and which has allowed him the freedom to write throughout his life.[Taken from the original programme material for this archive edition of Desert Island Discs]Favourite track: Le Ca Ira by Edith Piaf Book: The Air Publication 1234 (RAF Manual) Luxury: A communications receiver (receiving only).

Kirsty Young's castaway this week is the Liberal Democrat Treasury Spokesman, Vince Cable. He studied economics at Cambridge and had a rich career before entering parliament in 1997. Now, he's become something of a media darling; seen by many as one of the few people able to understand - and make credible suggestions about - the current financial crisis. In this personal interview, however, politics is largely set aside and instead Vince describes the home-life that shaped him as he grew up and the rich family life he has enjoyed as an adult. His fiercely ambitious father was an activist for the local Conservative party: he was talented, driven and passionate, but also overbearing and unwilling to hear voices of dissent. Vince dismayed his father by dropping his science degree in favour of economics and later outraged him by marrying his first wife, Olympia, who was from Kenya. Despite his father's view that mixed-race marriages 'didn't work', they were married for more than 13 years and raised their three children together before Olympia's death from cancer. After her death, he says, he envisaged a lonely old-age lay ahead - but an unpromising debate about free trade and agriculture brought him together with his second wife. Now he says he wears both his wedding rings together as a tribute to the two happy marriages he has enjoyed, he continues to go dancing every week with his second wife Rachel, as he did with Olympia and he is, he cheerfully confesses, a romantic.[Taken from the original programme material for this archive edition of Desert Island Discs]Favourite track: La Ci Darem La Mano from Don Giovanni by Wolfgang Amadeus Mozart Book: A Brief History of Time by Stephen Hawking Luxury: An Aston Martin car.

Kirsty Young's castaway this week is the poet Ruth Padel. She is a highly acclaimed writer who is fascinated with the natural world around her. She's said of her poetry: "wildness, and wild animals lie at the heart of what I feel about writing". And perhaps that's no surprise - she is the great-great-granddaughter of Charles Darwin. As a child, her hero was Bagheera - the black panther from The Jungle Book. For a time, she confesses, she used to want to be a black panther. Later, she simply wanted to marry one. As an adult she has spent several years travelling across India, Sumatra and parts of Russia tracking tigers and trying to understand their lives. She notes ruefully that while her illustrious ancestor was involved in understanding how different species came into being, her own work was more a matter of documenting their decline. Her interests have been with her since childhood. Back then, she says, "looking at nature properly, knowing the names of the plants, seeing how the petals worked, observing animal behaviour was just there. That was what you did. That was what being a person was."[Taken from the original programme material for this archive edition of Desert Island Discs]Favourite track: E Voi Ridete? - And you're laughing? by Wolfgang Amadeus Mozart Book: The Iliad by Homer Luxury: A lot of paper and pencils.

Kirsty Young's castaway this week is the adventurer and businessman Simon Murray. What many of us would struggle to do over three life-times he has managed in one - as a teenager, nursing a broken heart and determined to prove himself, he joined the French Foreign Legion. Fighting in the Algerian war, he risked his life many times over; combat was at close quarters and was very bloody. Next, he set his sights on business - he ran some of the most well-known companies in South East Asia and was one of Chris Patten's key allies during the handover of Hong Kong. Then, in his 60s and looking for a new challenge, he chanced upon the idea of polar adventure, and went on to become the oldest person to walk unsupported to the South Pole. But after all this, his greatest achievement, he says, is his marriage. Perhaps it's no surprise that his wife of 43 years, Jennifer, is the first woman to have flown a helicopter solo around the world. These days their three children try to curb their enthusiasm for dangerous pursuits. But, Simon snorts, the couple simply say: "we're not listening."This programme contains descriptions that some listeners may find disturbing.[Taken from the original programme material for this archive edition of Desert Island Discs]Favourite track: O Soave Fanciulla (Oh beautiful maiden) by Giacomo Puccini Book: Cautionary Tales by Hilaire Belloc Luxury: Lots of paper, pencil and pencil sharpener.

Kirsty Young's castaway this week is Baroness Haleh Afshar. An expert in Middle Eastern Affairs, she's a professor of politics and women's studies and Islamic law as well as being a cross-bench peer. She grew up in Iran and France living a life of huge privilege but, inspired by reading Jane Eyre, she decided she needed to learn to stand on her own two feet. She came to Britain as a boarding school pupil when she was 14 and has made her home here.She has been an outspoken critic of the Iranian regime and, coming from a long line of independent-minded women, that's little surprise. Her mother campaigned for women to have the vote while her grandmother refused to wear the veil. Though in her grandmother's case, that was because she thought she was too pretty to be covered up.[Taken from the original programme material for this archive edition of Desert Island Discs]Record: Prelude to Bach's Cello Suite No.1 Book: Collected poems by Hafiz Alternate to Bible: Koran Luxury: A rose bush.

Kirsty Young's castaway this week is James Nesbitt. He is one of our most popular and successful actors and his long list of credits includes Cold Feet, Bloody Sunday, Jekyll and Murphy's Law. In this warm and illuminating interview he recalls his childhood in County Antrim where he grew up in a close-knit, rural community. He was the only boy and the youngest of four children and, when he was told he was 'spoilt', says he always understood that it meant the same as 'loved'. His father was the headmaster of the local primary school and there was an expectation that his children would follow him to become teachers. But James was a keen actor and says it is only now, in his 40s, that he can look back clearly and see he always felt an affinity to being on the stage. The first role he was cast in was as the Artful Dodger in Oliver. It's a character, he jokes, that has stayed with him through many of the roles he has taken on since.[Taken from the original programme material for this archive edition of Desert Island Discs]Favourite track: Come Fly With Me by Frank Sinatra Book: Collected writings by James Lawton Luxury: A bottle of chilled Sancerre for every night.

Kirsty Young's castaway this week is the Oscar-winning film producer Michael Deeley. Over the past 40 years he's been involved in some of the most highly acclaimed movies we've seen, including Don't Look Now, The Deer Hunter and The Italian Job. Yet his job is one that's barely understood. Neither the artistic visionary nor the star player the producer, he says, is the person who is the ramrod-figure who causes a film to be made - buying the rights to stories, hiring actors, finding locations and overseeing the production. He fell into it - he'd always thought he'd be a diplomat or a lawyer - but a casual job ended up being a career of many decades standing. He says rather modestly, "I just found I had the knack".[Taken from the original programme material for this archive edition of Desert Island Discs]Favourite track: I'd Do Anything for Love (But I Won't Do That) by Meat Loaf Book: Decent translation of the Koran Luxury: Two hundred cases of vintage wine.