The Stem Cell Podcast

Dr. Celina Juliano is an Assistant Professor at the University of California, Davis. Her lab studies development and regeneration in the aquatic animal Hydra, which undergoes continual self-renewal, lacks senescence and has incredible regenerative capabilities.

Dr. Rameen Shakur is a Jansen Fellow in Cardiology and Personalized Medicine at the Koch Institute for Integrative Science at MIT, and the Founder of the medical device and algorithm company Cambridge Heartwear Ltd.

Dr. Stephane Angers is a Professor at the University of Toronto. He is an expert in the field of signal transduction, working to understand the signaling mechanisms underlying the Wnt and Hedgehog families of growth factors and the large family of G protein-coupled receptors.

Dr. Paul Burridge from Northwestern University talks about his work using human iPSCs to model cardiomyopathy and heart failure.

Back in June 2019, we attended the ISSCR annual conference in Los Angeles, California! Here is the last of three special episodes featuring some of the top researchers in the field, and junior trainees.

Dr. Pekka Katajisto studies the mechanisms that lead to the decline in tissue regeneration during aging.

Back in June 2019, we attended the ISSCR annual conference in Los Angeles, California! Here is the second of three special episodes featuring some of the top researchers in the field, and junior trainees.

Guest: Dr. Alysson Muotri is a Professor in the Departments of Pediatrics and Cellular & Molecular Medicine at the University of California, San Diego (UCSD) School of Medicine, and Co-Director of the UCSD Stem Cell Program. His research focuses on modeling neurological diseases using human iPSCs, and he is leading a project investigating the effect of microgravity on human brain organoids. Featured Products and Resources: STEMdiff™ Cerebral Organoid Kit Organoid Research Resources Resources and Links Detecting an Unreported Zika Outbreak using Genetics - By sequencing Zika virus and analyzing travel patterns, a previously unreported 2017 Zika outbreak in Cuba has been identified. Ketogenic Diet Supports Intestinal Stem Cell Proliferation - Researchers have found that ketone bodies enhance the activity of intestinal stem cells, while a glucose-rich diet has the opposite effect. Cancer Cells 'Corrupt' Their Healthy Neighbours - Scientists have developed a technique whereby metastatic cancer cells release a cell-penetrating fluorescent protein, allowing them to study the tumor microenvironment. 3D Heart Cell-on-Chip Platform - Investigators have developed an organ-on-an-electronic-chip platform, which uses biosensors to measure the electrophysiology of 3D cardiac spheroids. Photo Reference: Courtesy of Dr. Alysson Muotri Subscribe to our newsletter! Never miss updates about new episodes. Subscribe

Intro: Back in June 2019, we attended the International Society for Stem Cell Research's (ISSCR) annual conference in Los Angeles, California! Here is the first of three special episodes featuring interviews with some of the top researchers in the stem cell field, as well as with up-and-coming junior trainees who talked to Daylon about their research and experience at the conference. Junior Trainees: We asked Junior Trainees the following question: WHAT IS THE MOST EXCITING RESEARCH THAT YOU'VE SEEN AT ISSCR? Dr. Amritha Jaishankar; Associate Director, Maryland Stem Cell Research Fund Aaron Sandoval; Undergraduate Student, University of Florida Ana Rita Leitoguinho; Graduate Student, Murdoch Children's Research Institute Alejandro Torres; Graduate Student, University of California, Los Angeles Oriana Genolet; Graduate Student, Max Planck Institute Ojeni Touma; Intern, California Institute for Regenerative Medicine Vivian Lu; Graduate Student, University of California, Los Angeles Senior Researchers: Dr. Senta Georgia, PhD; Principal Investigator, Children's Hospital Los Angeles Dr. Georgia is investigating how pancreatic beta cells differentiate during organogenesis, how they increase their cell numbers during normal growth and in response to metabolic stress, and how they can be regenerated as a cellular therapy for diabetic patients. Dr. Tenneille Ludwig, PhD; Director, WiCell Stem Cell Bank Dr. Ludwig's expertise is in optimizing human pluripotent cell culture conditions, focusing on media development and biobanking. She created the first defined, feeder-free culture system for human embryonic stem cells. Dr. Kim Jensen, PhD; Associate Professor, Danish Stem Cell Centre Dr. Jensen seeks to identify and characterize the regulatory mechanisms that control cell fate during development, homeostasis and diseases such as cancer. He focuses on the epithelia of the gastrointestinal tract. Sir John Gurdon, PhD, DSc, FRS; Distinguished Group Leader, University of Cambridge Sir John Gurdon was awarded the 2012 Nobel Prize in Physiology or Medicine for his pioneering work in nuclear transplantation and cloning. His research focuses on nuclear reprogramming of somatic cells by oocytes and eggs of amphibians. Dr. Daniel Besser, PhD; Managing Director, German Stem Cell Network Dr. Besser studies signal transduction mechanisms in pluripotency and reprogramming of human and mouse embryonic stem cells. At the German Stem Cell Network, he works on creating synergies between basic and applied stem cell research and fostering scientific communication and outreach. Subscribe to our newsletter! Never miss updates about new episodes. Subscribe

Guest: Dr. Steve Szilvassy is the Senior Director, Head of Hematopoietic Products at STEMCELL Technologies. He has over 25 years of experience in the fields of hematology and oncology, having held a variety of research positions, including research scientist and project team leader, in both academia and industry. Featured Products and Resources: Live Webinar: Optimized Workflows for High-Efficiency Genome Editing in Stem and Primary Cell Types Jobs at STEMCELL Technologies Resources and Links Blastocyst-Like Structures from Mouse Stem Cells - Researchers have generated 3D blastocyst-like structures from mouse PSCs that could be implanted into the uterus and grow before resorption. Making Old Brain Stem Cells Young - Investigators have found that increasing brain stiffness during aging leads to the dysfunction of oligodendrocyte progenitor cells, but showed that the effects can be reversed. Stem Cell Combination Repairs Damaged Hearts - Heart muscle cells and epicardial cells derived from human ESCs were co-transplanted into rats with damaged hearts, generating grafts that had greater cell growth and that lived longer. Using CAR-T against HIV - Scientists have developed duoCAR-T cells that target multiple sites on the HIV envelope, and that were able to kill HIV cells while resisting infection themselves. Photo Reference: Courtesy of Dr. Stephen Szilvassy Subscribe to our newsletter! Never miss updates about new episodes. Subscribe