Unexpected Elements

With the announcement in the UK of investment in rapid testing for people who may not have Covid -19 we ask why is this only happening now? For months on this programme we’ve featured scientific research suggesting such a strategy would be the quickest way to end the pandemic. We speak with Connie Cepko and Brian Rabe who have developed a rapid test and Manu Prakash who is currently rolling it out to countries in the global south.Could a huge motorcycle rally really have been the source of over a quarter of a million Covid -19 infections? That’s the finding of a study by economist Andrew Friedson he tells us how mobile phone data helped to determine that figure. And the politics of vaccines, Many health officials in the US have spoken out against president Trumps claim that a vaccine may be ready before the November presidential election. Helen Branswell from Stat news tells us why there is so much concern over political attempts to manipulate science. And Many of us enjoy cooking – but when did we switch from eating our food raw, to heating it? Listener Logan enjoys his beef burgers rare, but wants to know why he still feels compelled to grill them? Presenter Anand Jagatia travels to a remote South African cave where our ancestors first used fire at least a million years ago, which one man says could help prove when our species started cooking. And he talks to a scientist who shows how the composition of food changes when it’s cooked, to allow us more access to give us more access to calories - and hears how a completely raw food diet could have disastrous consequences for health.(Image:Getty Images)

A new survey of the volcano's activity suggests there may be an eruption in the next 4 to 7 years. It's a particular concern for the populations of Goma and Gisenyi, two cites between the volcano and lake Kivu. As we hear from the director of the Goma Volcano Observatory Katcho Karume, the city of Goma in particular has expanded so much that many people now live right next to fissures in the flank of the volcano through which any eruption would likely occur.Hurricane Laura made landfall in Louisiana's main area of swamp land, missing big urban areas to either side. It was a lucky escape for many, but as hurricane historian Jill Trepanier tells us such extreme weather events do seem to be more frequent and potentially more destructive. And wildfires ravaging California and other Western US states may have been intensified by changes to global weather systems . Climate scientist Bill Lau says those weather systems in turn have been modified by man-made climate change.In November 2018 a Chinese scientist announced he had edited the genes of twin girls. The announcement was greeted with horror by many researchers in the field. Now a way to regulate gene editing internationally has been proposed by some of the world's leading scientific institutions. Kay Davies co-author of their report explains the plan.What does science say about controlling urination, and other bodily functions? We tackle three queries about peeing triggers, pooing positions and missing sweat. This episode CrowdScience presenter Marnie Chesterton poses some of the best listener follow-up questions that have landed in our inbox to a panel of experts.Listener Samuel in Ghana is wondering why watery sounds seem to induce urination. Producer Melanie Brown heads out to survey whether this is the case for individuals in an actual crowd at a public fountain in London. And urologist and trustee of the International Continence Society Marcus Drake talks Marnie through how he uses the sound of running water during his work as a hospital doctor helping patients with common but distressing peeing issues, and the limitations of research into this question.And he's not the only listener who wants us to dig deeper into topics we've explored on the show before. Anna in Tokyo also got in touch after hearing our show about toilets, to ask if there is a toilet design that is most 'natural' for our health. Gastroenterologist Anton Emmanuel explains why small changes in people's posture whilst pooing can have a significant impact on their quality of life.Finally, listeners Stelle, James and Joel emailed crowdscience@bbc.co.uk after hearing Marnie investigate hyperhidrosis: Sweating too much. They and their relatives experience the opposite.(Main Image: Sunset, Goma, Democratic Republic of Congo. Credit: Shamim Shorif Susom / EyeEm / Getty Images)

This week Science in Action examines the evidence around the Trump Administration’s emergency use authorisation of convalescent plasma therapy for the treatment of Covid-19. Donald Trump described its US-wide roll-out as ‘historic’ but the majority of scientists and doctors disagree, questioning the scientific basis for the government’s decision. Roland Pease talks to Mayo Clinic’s Michael Joyner, the leader of the convalescent plasma therapy study on which the action was based. The Mayo Clinic trial involved a large number of patients but none of them were compared to Covid-19 patients who were not treated with convalescent plasma. Trials that incorporate that comparison are the only way to properly assess the therapy’s effectiveness. Roland talks to Martin Landray of the University of Oxford who is testing convalescent plasma therapy in the UK’s Recovery randomised control trial, and to medical ethicist Alison Bateman-House of the New York University Grossman School of Medicine.We also talk to nanotechnologist Marc Miskin about the million-strong army of microscopic robots he’s creating in his lab at the University of Pennsylvania.The idea of creating underwater habitats has captured the imagination of writers, thinkers and scientists for decades. However, despite numerous grand visions, these dreams of aquatic metropolises have not yet come to fruition. Crowdscience listener and scuba enthusiast Jack wonders whether - given improved technology and the growing environmental pressures facing humans on land - it is time to reconsider the ocean as an alternative permanent living space for humans. Marnie Chesterton dons her flippers for Crowdscience in search of the oceanographers and architects who have dedicated their lives to designing vessels, labs and underwater habitats. She explores whether oceanic cities remain a sci-fi dream or a realistic solution to some of our modern challenges. Can the oceans’ largely unexplored resources be harnessed to support living underwater?(Main image: New York lab tests serum from recovered covid-19 patients for possible therapy. Credit: Misha Friedman / Getty Images)

Has the loss from Greenland’s vast ice sheet reached a tipping point? According to glaciologist Michalea King, the rate at which its ice flows into the sea stepped up about 15 years ago. The process of glacial retreat is outpacing the accumulation snow and ice in Greenland’s interior and the loss of Greenland’s ice to the Ocean is set to continue for many years to come. An international study of past climate changes during the last ice age reveals how fast changes to weather patterns and climate states can reverberate around the world. During the last ice age, when temperatures rose suddenly in Greenland a series of changes to the climate in Europe and the monsoons in Asia and South America occurred almost simultaneously - within decades of each other. Climate scientists Eric Wolff and Ellen Corrick have discovered this through studies of stalagmites from caves around the world. It’s a demonstration of how rapidly and dramatically the Earth’s atmospheric system can change when it’s perturbed.Was the hottest temperature ever on Earth recorded last weekend? A weather station in Death Valley in California recorded a temperature of 54.4 degrees C. Roland Pease discusses the controversy with extreme weather historian Christopher Burt.Andrea Dupree of Harvard-Smithsonian Center for Astrophysics reveals the latest on the giant star Betelgeuse which to everyone’s amazement dimmed dramatically at the beginning of the year. At the time some people wondered whether it was about to explode as a supernova but Andrea’s new findings suggest an event at the star which is almost as extraordinary. If you’re one of the millions of people who used lockdown to try something new like baking sourdough bread, you may well be wondering what’s happening chemically inside your loaf, especially if the end result keeps changing. Well, you’re not alone. Listeners Soheil and Sean are both keen bakers but want to know more about the thing that makes bread rise: yeast. What is yeast? Where does it come from and can you catch it? And how hard is it to ‘make’ yourself? Soon after lockdown took effect, commercial supplies of the stuff disappeared from supermarket shelves across the globe. The shortage also affected brewers the world over. A big fan of yeast in most of its forms, Marnie Chesterton took on the challenge of creating her own. She talks to the brewers who hunt rare strains to create the perfect beer, and hears from the biologist who says these amazing microbes, used for thousands of years, could be used to make food production more sustainable. And she discovers how this simple ingredient could be instrumental in the fight against climate change.(Image: Masses of ice break off from the edge of a glacier. Credit: Press Association)

Russia’s President Putin announced the registration of a vaccine for coronavirus. This was reported with widespread alarm amid concerns over safety, but as BBC Russian Service’s Sergei Goryashko, tells us the announcement was a political move to capture the headlines.Investigations by Alexandra Reynolds and Hooman Poor at New York’s Mount Sinai Medical Centre have revealed why some Covid 19 patients have low oxygen levels, but don’t have breathing difficulties. The answer came when looking for signs of stroke in the brain.Nisreen Alwan, a specialist in public health at Southampton University is concerned about the quality of life of people who have had a Covid -19 infection. Being classed as recovered is not enough she says and we need to look more at recurring health problems associated with the disease.And Cardiff University’s Haley Gomez has news of a tantalising discovery. The detection of a neutron star hidden in a dust cloud for more than 30 years.Squelching into the science of slime, Chhavi Sachdev seeks to find out why it took so long for listener Helen Tyson to remove slime from her fingers, after she picked up a tiny slug while gardening. This unfortunate and hugely repulsive experience set Helen to wonder what it is about the structure of slug slime that makes it gloopy, so she sent Chhavi to meet with slug slime expert Professor Andrew Smith who reveals how the complex molecular structure of this pervasive fluid makes it so difficult to scrub off.Slime is used by all sorts of creatures including the Giant African Land snail, which invaded India by hitching a ride on imported timber. But invasive species biologist Dr TV Sajeev reveals that these snails are themselves giving a lift to another meningitis-causing parasite that can infect people. Chhavi looks for these massive molluscs in her own garden in Mumbai. Marine biologist Helen Scales describes how animals can use slime for catching food, mating, defence, or even transportation, and Chhavi speaks with Dr Adam Celiz who has been inspired by this slimy adaptability to create a tool that can provide new cells to replace damaged heart cells after a cardiac arrest. Slugs, snails and even fish keep a variety of useful chemicals in their slime. Some make them taste bitter, and others numb the mouth of predators, but they may also prevent the animals from contracting infections. Dr Sarah Pitt has investigated these compounds in the slimy mucus of a garden snail and discovered an antibiotic that is brand new to science. Slime is pretty disgusting, but it’s also completely fascinating. (Image:President Putin. Credit: Reuters)

If the world does not curb its greenhouse gas emissions, by the end of this century, the number of people dying annually because of extreme heat will be greater than the current global death toll from infectious diseases - that’s all infectiousness diseases, from malaria to diarrhoeal diseases to HIV. This is the grim assessment of climate researchers and economists of the Climate Impact Lab in the largest global study to date of health and financial impacts of temperature-related deaths. Roland Pease talks to Solomon Hsiang of the University of California, Berkeley.UK ecologists have new insights about how diseases jump the species barrier from wildlife to humans. With a global survey of land use and biodiversity, they’ve discovered that when natural habitats are converted to farmland or urbanised, the animal species that survive the change in greatest number are those species which carry viruses and bacteria with the potential to spread to us. This is particularly the case, says Rory Gibb of the University College London, with disease-carrying rodent species, bats and birds.Do past infections by mild cold coronaviruses prepare the immune systems of some people for infection by SARS-CoV-2? Could immune memory T cells made in response to these cold viruses lessen the severity of Covid-19? Alessandro Sette and Daniela Weiskopf of the La Jolla Institute for Immunology lead the team which published the latest contributions to these questions.Anglerfish are perhaps the weirdest inhabitants of the deep sea. Their sex lives are particularly strange because finding partners in the dark expanse of the ocean abyss is hard. Females are much bigger than males. When a male finds a female, he latches on her body with his teeth and over a couple of weeks, their flesh fuses so he is permanently attached. Her blood supplies him with all the food and oxygen he needs and he becomes an ever present supply of sperm whenever she produces eggs. But this fusion should be impossible. The female’s immune system should be rejecting her partner like a mismatched organ transplant. German scientists have now discovered that these fish do this by giving up the production of antibodies and immune T cells – essential for fighting infections in all other animals including us. It was a shocking discovery for Prof Thomas Boehm at the Max Planck Institute in Freiburg.Anyone else had their flight cancelled? The COVID 19 pandemic has had a huge impact on air travel – air traffic in 2020 is expected to be down 50 per cent on last year. But beyond the obvious disruption to business and people’s lives, how might the quieter skies affect our weather and climate?One curious listener, Jeroen Wijnands, who lives next to Schiphol airport in the Netherlands, noticed how there were fewer clouds and barely any rainfall since the flights dropped off. Could airplanes affect our local weather?Also, did we learn anything from another occasion when airplanes were grounded, during the post-9/11 shutdown? How will the current period impact our future climate?Marnie Chesterton investigates this question and discovers some of the surprising effects that grounded aircraft are having: on cloud formation, forecasting and climate change.(Image: Relatives of heatstroke victims, their heads covered with wet towels, wait outside a hospital during a heatwave in Karachi. .Credit: Rizwan Tabassum/AFP via Getty Images)

NASA launches its new robotic mission to Mars. The rover, Perseverance, will land in a 50 kilometre wide crater which looks like it was filled by a lake about 4 billion years ago - the time when life on Earth was getting started. Mission scientist Melissa Rice explains why this is one of the most promising places on Mars to continue the search for past life on the red planet.Japanese and US scientists have revived microbes that have been buried at the bottom of the Pacific Ocean for 100 million years. Sampled from compacted mud 70 metres below the seafloor and beneath 6 kilometre of water, Yuki Morono and Steve D'Hondt admit they struggle to understand how the bacteria have survived for so long. Science in Action celebrates the little unknown oceanographer Marie Tharp who in the late 1950s discovered the mid-Atlantic ridge which helped to launch the plate tectonics revolution in earth sciences. It would be Tharp's 100th birthday this week. New research this week suggests that coronaviruses capable of infecting humans have been in bats for 40 to 70 years, and that there may be numerous and as yet undetected viruses like the Covid-19 virus in bat populations with the potential to cause future pandemics. Their message is that we should be sampling and testing wild bat colonies much more extensively than currently. Their findings provide further evidence against the unfounded claim that the Covid-19 virus originated from the Wuhan Institute of Virology in China. Roland Pease talks to Dr Maciej Boni at Pennsylvania State University.Listener Avalon from Australia wants to know why people use conspiracy theories to explain shocking events. Are we more likely to believe conspiracy theories in times of adversity? What purpose do conspiracy theories serve in society? Marnie Chesterton speaks to the scientists to explain their popularity, even in the face of seemingly irrefutable evidence. (Image: NASA's Perseverance Mars rover. Credit: Illustration provided by Jet Propulsion Laboratory in Pasadena, California. NASA/JPL-Caltech/Handout via REUTERS)

There's been encouraging news about the Oxford Covid-19 vaccine this week from a trial involving about 1,000 people. But how great is the challenge in scaling up from making a few thousand doses of the vaccine to manufacturing two billion by the end of this year? Sandy Douglas of Oxford's Jenner Institute explains how they plan to mass-produce the vaccine safely given the speed and magnitude of the scale up. A new kind of treatment for Covid-19 may come from an unlikely source: llamas and alpacas, the South American relatives of the camel. Camelids produce unusually small and simple antibodies against viruses, including the coronavirus. This feature may make these molecules an effective Covid-19 therapy. Jane Chambers reports on research in Chile and the UK.Also in the programme: what has made just a few mosquito species evolve a preference for biting humans, and the theory that 800 million years ago the Moon and the Earth were bombarded by a shower of asteroids which plunged the Earth into a global ice age - an event which changed the course of the evolution of life. These days we're more acquainted with soap than ever before, as we lather up to help stop the spread of coronavirus. And for CrowdScience listener Sharon, this set off a steady stream of soapy questions: how does soap actually work? How was it discovered in the first place, long before anyone knew anything about germs? Are different things used for washing around the world, and are some soaps better than others? We set up a CrowdScience home laboratory to explore the soap making process with advice from science-based beauty blogger Dr Michelle Wong, and find out what it is about soap's chemistry that gives it its germ-fighting superpowers. Soap has been around for at least 4000 years; we compare ancient soap making to modern methods, and hear about some of the soap alternatives used around the world, like the soap berries of India.And as for the question of whether some soaps are better than others? We discover why antibacterial soaps aren't necessarily a good idea, and why putting a toy inside a bar of soap might be more important than tweaking its ingredients.(Image: A team of experts at the University of Oxford are working to develop a vaccine that could prevent people from getting Covid-19. Credit: Press Association)

Science in Action looks at some of the latest research on how response of our immune system to infection by the coronavirus. Researchers at Kings College London find that protective antibodies appear to fade away after about three months following infection whereas a team at the Karolinska Institute has discovered that although antibodies may decline, other important players called T cells in our defences do not. Dr’s Katie Doores and Marcus Buggert talk about the implications of these discoveries for the quest for a vaccine against the coronavirus. Roland Pease also talks to Dr Barney Graham of the National Institute of Allergy and Infectious Diseases in the United States about the results from the Phase 1 trial of novel type of vaccine against the virus. NIAID have partnered with biotech company Moderna to produce the first mRNA vaccine in the Institute’s pandemic preparedness program. Biologist Dr Sonja Wild tells Roland about the remarkable fishing strategy devised by dolphins in Shark Bay, Australia. They chase fish into the empty shell of giant sea snails, then take the shells to the surface and tip the fish into their mouths. Dr Wild’s 7 years of research has revealed how the dolphins have learned to do this. Think of the oceans and an empty and peaceful expanse relatively untouched by humankind might come to mind. But is this peace an illusion? CrowdScience listener Dani wants to know if the noise of shipping and other human activity on the oceans is impacting on sea life.To find out, Marnie Chesterton takes a deep dive to learn how marine animals have evolved to use sound; from navigating their environments to finding a mate or hiding from prey. She then speaks to a scientist who is using acoustic observatories to track the many ways human activity - like sonar and shipping – can interfere.Marnie virtually visits a German lab which tests the ears of beached whales, dolphins and seals from around the world to try and ascertain whether they suffered hearing damage, and what might have caused it. What other smaller creatures are negatively impacted by underwater noise? Marnie learns that acoustic trauma is more widespread than first thought.As human life continues to expand along ocean waters, what is being done to reduce the impact of sound? Marnie meets some of the designers at the forefront of naval architecture to see how ship design, from propellers to air bubbles and even wind powered vessels can contribute to reducing the racket in the oceans.Main image: Abs COVID-19 antibody - Viral Infection concept. Credit: Getty Images

African scientists have developed a reliable, quick and cheap testing method which could be used by worldwide as the basis for mass testing programmes.The method, which produces highly accurate results, is built around mathematical algorithms developed at the African Institute for Mathematical Sciences in Kigali. We speak to Neil Turok who founded the institute, Leon Mutesa Professor of human genetics on the government coronavirus task force, and Wilfred Ndifon, the mathematical biologist who devised the algorithm.The virus is mutating as it spreads, but what does this mean? There is particular concern over changes to the spike protein, part of the virus needed to enter human cells. Jeremy Luban has been analysing this mechanism. So far he says ongoing genetic changes seem unlikely to impact on the effectiveness of treatments for Covid -19.And Heatwaves are increasing, particularly in tropical regions, that’s the finding of a new analysis by climate scientist Sarah Perkins – Kirkpatrick.Worms are not the cutest of creatures. They’re slimy, often associated with death and tend to bring on feelings of disgust in many of us. But listener Dinesh thinks they’re underrated and wants to know whether earthworms could be the key to our planet’s future agricultural success? He’s an organic farmer in India’s Tamil Nadu province who grows these annelids to add to the soil, and he wants Crowdscience to find out exactly what they’re doing. Anand Jagatia dons his gardening gloves and digs the dirt on these remarkable creatures, discovering how they can help improve soil quality, prevent fields from becoming waterlogged, and improve microbial numbers, all of which has the potential to increase crop yield.But he also investigates the so-called ‘earthworm dilemma’ and the idea that in some parts of the world, boreal forest worms are releasing carbon back into the atmosphere, which could have dangerous consequences for climate change.Main image: People stand in white circles drawn on the ground to adhere to social distancing in Kigali, Rwanda, on May 4, 2020, Photo by Simon Wohlfahrt / AFP via Getty Images