Unexpected Elements

NASA launches its new robotic mission to Mars. The rover, Perseverance, will land in a 50 kilometre wide crater which looks like it was filled by a lake about 4 billion years ago - the time when life on Earth was getting started. Mission scientist Melissa Rice explains why this is one of the most promising places on Mars to continue the search for past life on the red planet.Japanese and US scientists have revived microbes that have been buried at the bottom of the Pacific Ocean for 100 million years. Sampled from compacted mud 70 metres below the seafloor and beneath 6 kilometre of water, Yuki Morono and Steve D'Hondt admit they struggle to understand how the bacteria have survived for so long. Science in Action celebrates the little unknown oceanographer Marie Tharp who in the late 1950s discovered the mid-Atlantic ridge which helped to launch the plate tectonics revolution in earth sciences. It would be Tharp's 100th birthday this week. New research this week suggests that coronaviruses capable of infecting humans have been in bats for 40 to 70 years, and that there may be numerous and as yet undetected viruses like the Covid-19 virus in bat populations with the potential to cause future pandemics. Their message is that we should be sampling and testing wild bat colonies much more extensively than currently. Their findings provide further evidence against the unfounded claim that the Covid-19 virus originated from the Wuhan Institute of Virology in China. Roland Pease talks to Dr Maciej Boni at Pennsylvania State University.Listener Avalon from Australia wants to know why people use conspiracy theories to explain shocking events. Are we more likely to believe conspiracy theories in times of adversity? What purpose do conspiracy theories serve in society? Marnie Chesterton speaks to the scientists to explain their popularity, even in the face of seemingly irrefutable evidence. (Image: NASA's Perseverance Mars rover. Credit: Illustration provided by Jet Propulsion Laboratory in Pasadena, California. NASA/JPL-Caltech/Handout via REUTERS)

There's been encouraging news about the Oxford Covid-19 vaccine this week from a trial involving about 1,000 people. But how great is the challenge in scaling up from making a few thousand doses of the vaccine to manufacturing two billion by the end of this year? Sandy Douglas of Oxford's Jenner Institute explains how they plan to mass-produce the vaccine safely given the speed and magnitude of the scale up. A new kind of treatment for Covid-19 may come from an unlikely source: llamas and alpacas, the South American relatives of the camel. Camelids produce unusually small and simple antibodies against viruses, including the coronavirus. This feature may make these molecules an effective Covid-19 therapy. Jane Chambers reports on research in Chile and the UK.Also in the programme: what has made just a few mosquito species evolve a preference for biting humans, and the theory that 800 million years ago the Moon and the Earth were bombarded by a shower of asteroids which plunged the Earth into a global ice age - an event which changed the course of the evolution of life. These days we're more acquainted with soap than ever before, as we lather up to help stop the spread of coronavirus. And for CrowdScience listener Sharon, this set off a steady stream of soapy questions: how does soap actually work? How was it discovered in the first place, long before anyone knew anything about germs? Are different things used for washing around the world, and are some soaps better than others? We set up a CrowdScience home laboratory to explore the soap making process with advice from science-based beauty blogger Dr Michelle Wong, and find out what it is about soap's chemistry that gives it its germ-fighting superpowers. Soap has been around for at least 4000 years; we compare ancient soap making to modern methods, and hear about some of the soap alternatives used around the world, like the soap berries of India.And as for the question of whether some soaps are better than others? We discover why antibacterial soaps aren't necessarily a good idea, and why putting a toy inside a bar of soap might be more important than tweaking its ingredients.(Image: A team of experts at the University of Oxford are working to develop a vaccine that could prevent people from getting Covid-19. Credit: Press Association)

Science in Action looks at some of the latest research on how response of our immune system to infection by the coronavirus. Researchers at Kings College London find that protective antibodies appear to fade away after about three months following infection whereas a team at the Karolinska Institute has discovered that although antibodies may decline, other important players called T cells in our defences do not. Dr’s Katie Doores and Marcus Buggert talk about the implications of these discoveries for the quest for a vaccine against the coronavirus. Roland Pease also talks to Dr Barney Graham of the National Institute of Allergy and Infectious Diseases in the United States about the results from the Phase 1 trial of novel type of vaccine against the virus. NIAID have partnered with biotech company Moderna to produce the first mRNA vaccine in the Institute’s pandemic preparedness program. Biologist Dr Sonja Wild tells Roland about the remarkable fishing strategy devised by dolphins in Shark Bay, Australia. They chase fish into the empty shell of giant sea snails, then take the shells to the surface and tip the fish into their mouths. Dr Wild’s 7 years of research has revealed how the dolphins have learned to do this. Think of the oceans and an empty and peaceful expanse relatively untouched by humankind might come to mind. But is this peace an illusion? CrowdScience listener Dani wants to know if the noise of shipping and other human activity on the oceans is impacting on sea life.To find out, Marnie Chesterton takes a deep dive to learn how marine animals have evolved to use sound; from navigating their environments to finding a mate or hiding from prey. She then speaks to a scientist who is using acoustic observatories to track the many ways human activity - like sonar and shipping – can interfere.Marnie virtually visits a German lab which tests the ears of beached whales, dolphins and seals from around the world to try and ascertain whether they suffered hearing damage, and what might have caused it. What other smaller creatures are negatively impacted by underwater noise? Marnie learns that acoustic trauma is more widespread than first thought.As human life continues to expand along ocean waters, what is being done to reduce the impact of sound? Marnie meets some of the designers at the forefront of naval architecture to see how ship design, from propellers to air bubbles and even wind powered vessels can contribute to reducing the racket in the oceans.Main image: Abs COVID-19 antibody - Viral Infection concept. Credit: Getty Images

African scientists have developed a reliable, quick and cheap testing method which could be used by worldwide as the basis for mass testing programmes.The method, which produces highly accurate results, is built around mathematical algorithms developed at the African Institute for Mathematical Sciences in Kigali. We speak to Neil Turok who founded the institute, Leon Mutesa Professor of human genetics on the government coronavirus task force, and Wilfred Ndifon, the mathematical biologist who devised the algorithm.The virus is mutating as it spreads, but what does this mean? There is particular concern over changes to the spike protein, part of the virus needed to enter human cells. Jeremy Luban has been analysing this mechanism. So far he says ongoing genetic changes seem unlikely to impact on the effectiveness of treatments for Covid -19.And Heatwaves are increasing, particularly in tropical regions, that’s the finding of a new analysis by climate scientist Sarah Perkins – Kirkpatrick.Worms are not the cutest of creatures. They’re slimy, often associated with death and tend to bring on feelings of disgust in many of us. But listener Dinesh thinks they’re underrated and wants to know whether earthworms could be the key to our planet’s future agricultural success? He’s an organic farmer in India’s Tamil Nadu province who grows these annelids to add to the soil, and he wants Crowdscience to find out exactly what they’re doing. Anand Jagatia dons his gardening gloves and digs the dirt on these remarkable creatures, discovering how they can help improve soil quality, prevent fields from becoming waterlogged, and improve microbial numbers, all of which has the potential to increase crop yield.But he also investigates the so-called ‘earthworm dilemma’ and the idea that in some parts of the world, boreal forest worms are releasing carbon back into the atmosphere, which could have dangerous consequences for climate change.Main image: People stand in white circles drawn on the ground to adhere to social distancing in Kigali, Rwanda, on May 4, 2020, Photo by Simon Wohlfahrt / AFP via Getty Images

Studies in children who have been severely affected by Covid-19 in Italy, Britain and the US are showing the same thing – a range of symptoms linked to an overactive immune system. Elizabeth Whittaker from London’s Imperial College discusses the similarities in these cases and possible reasons for this syndrome with Shanna Kowalsky from Mount Sinai hospital in New York. How much should drugs for Covid-19 cost? Remdesivir, which has shown promise against the virus, has been priced at over $2000 for a course of treatment, but drug price analyst Andrew Hill says the cost of production is actually below $10.And how about some really alternative energy? Marion Cromb at Glasgow University has run an experiment to simulate a spinning black hole. In theory, a rocket sent to an equivalent real black hole could use its rotation as a power source.Shoes are a surprisingly recent human invention. But running isn’t. That means for most of our time on the planet, we’ve run barefoot. Today, in most countries, it’s rare to see people out in public without shoes, let alone running. But might our aversion to the free foot be causing us pain?CrowdScience mega-fan Hnin is an experienced runner - she enjoys ultra-marathons back home in Australia. But about six months ago she developed extreme foot pain, the condition Plantar Fasciitis, and this meant she had to stop doing what she loves. She reached out to CrowdScience presenter Chhavi Sachdev, to find out if barefoot running could reduce her pain and improve her performance. Simply put, is barefoot running better? In an attempt to find Hnin some answers, Chhavi hits the ground… running. Literally throwing off her own shoes on the streets of her home city of Mumbai, India, to see how feeling the ground can change her whole gait. And with Prof. Dan Lieberman, Chhavi learns what sets the human runner apart from other species, while uncovering the strange form our feet have. She speaks with Dr Peter Francis, a researcher whose life’s work has focused on curing the pain in his own feet and learning how to help others.But performance is also important for runners. Biomechanics and shoe expert Dr Sharon Dixon explains how modifications to the sports-shoe are helping marathon runners set records, and blade-running athlete Kiran Kanojia shows Chhavi how the technology behind her two prosthetic legs let her emulate either natural walking or natural running. (Image: Getty Images)

A record summer temperature in Siberia is an indication of major changes in the Arctic climate. Changing weather patterns there have a knock on effect for other parts of the planet says Climatologist Steve VavrusChile appeared to get Covid-19 under control, but in reality the virus was spreading uncontrollably through poor areas, As we hear from our correspondent in Santiago Jane Chambers, the lockdown has tightened but cases continue to rise.And could mass testing using new saliva tests help control or even end the epidemic? Epidemiologist Julian Peto tells us about his plan which is designed to contain the virus within individual households and stop community spread. Experiments to investigate dark matter have produced some tantalising results, Physicist Laura Manenti says it’s not confirmation of detection, but potentially close. If you put one person’s blood into another person , sometimes it’s fine and sometimes it’s a death sentence. French physician Jean-Baptiste Denis discovered this when he performed the first blood transfusion back in 1667. He put the blood of a lamb into a 15-year boy. The teenager survived but Denis’s third attempt killed the patient and led to a murder charge.In 1900, Austrian doctor Karl Landsteiner discovered the reason for this lottery – blood types. The red blood cells in our bodies are decorated with different marker molecules called antigens. These define us as A, B, AB or O blood type. And this is just one of 38 different systems for classifying our blood. CrowdScience listeners have discovered that we aren’t the only animal with blood types and want to know more. Dogs have 12 different blood groups, so how do they cope when they need a transfusion? CrowdScience meets some very good dogs who donate a pint to the pet blood bank in return for a toy and a treat. Each pint saving up to 4 other dogs’ lives. We also hear how examining our blood types can tell us more about our links to our ape-like cousins and how the human species spread around the world. And what about the future of blood types – can we use science, and animal blood to get around the problems of transfusions?(Image: Rural Scene in Verkhoyansk. Credit: Dean Conger/Corbis via Getty Images)

A multi arm trial testing a range of drugs has shown that readily available steroids can be lifesaving for people severely ill with Covid-19. Max Parmar, head of the UK Medical Research Council’s clinical trials unit says the trial design, where many potential drugs can be tested against the same controls, is key to producing results quickly. As it spreads around the world SARS-CoV-2 is mutating. But what does this mean? These mutations are part of a natural process and some researchers are finding they make no real difference to patient outcomes so far, but others are concerned the virus may become more dangerous. Neville Sanjana from New York University has been running lab tests on the mutant virus.Measles mutated from an animal virus, developing the ability to jump from cattle to human around 2,500 years ago. Sebastien Calvignac-Spencer from Germany’s Robert Koch Institute tracked its origins using preserved lung samples from centuries old measles victims. Covid -19 has become a magnet for conspiracy theorists. A common unfounded claim is that the virus was deliberately manufactured. During the boredom of lockdown such ideas have taken off online, with conspiracy videos receiving millions of views. We speak to scientists who have been targeted, and become the subject of this online misinformation. Also What exactly it means to be conscious has long been a question of profound debate amongst philosophers, and more recently, scientists. There are no easy answers, and it gets even trickier when you start asking whether animals are conscious: how can you find out about their subjective experience when they can’t tell you about it?Never afraid to tackle the impossible, CrowdScience is looking for answers after listener Natalie got in touch. She has lived with her cat for years and has a strong sense that he has thoughts and feelings: he has his own personality, acts in complex ways, and even has ‘grumpy days’. But is this consciousness? Is there any way of scientifically testing for it? How different from our own inner world is that of a cat, an octopus, or a bumblebee? And if we can find any answers to these puzzling questions, how does that affect the way we treat animals - not just our pets, but all the animals we share our planet with?We meet Natalie and her cat, and discover how scientists have explored the minds of pigs, cows and cuttlefish. Helping us ponder the elusive question of animal consciousness are philosopher Peter Godfrey-Smith, neuroscientist Anil Seth, animal welfare expert Donald Broom, ethicist Jessica Pierce, and comparative psychologist Alex Schnell.Featuring David Seddon as the voice of Chicco the Cat.(Image: Doctor examines Covid-19 virus patient. Credit: Getty Images)

Despite the Covid-19 pandemic efforts to counter massive swarms of locusts across East Africa have continued. In many places this has been very effective, killing up to 90% of locusts. However, the threat of repeated waves of locusts remains says Cyril Ferrand, who leads the UN Food and Agriculture Organisation's Resilience Team in East Africa.Conversely West Africa is unaffected by locusts and with a block on imports local producers have seen demand grow for their produce, an unusual positive effect from the pandemic according to Sandrine Dury from the French agricultural research agency CIRAD.We examine the potential for a second wave of coronavirus as many countries relax lockdown measures, businesses reopen and mass protests take to the streets. Epidemiologist Carl Bergstrom is interested in working out which of these movements is likely to have the most impact.And from South Africa, how radio telescope engineers there have turned their hands to developing new ventilators appropriate for regional needs.And we were bowled over by a question from one CrowdScience listener in Australia wants to know how likely it is that the atoms in his body have been used in someone else’s body? We all like to think we are unique; no one is quite like us. But is that really true?Presenter Marnie Chesterton tackles Moshe’s question with help from every area of science. From geologists helping us work out how many atoms are on the Earth’s surface to biologists helping us work out how many atoms each body uses. Perhaps we are much less special than we think.

Autopsies show Covid 19 can affect the brain and other organs. Pathologist Mary Fowkes from the Icahn School of Medicine at Mount Sinai found the signs of stroke - unusually in young people, as well as a disruption of the immune system throughout the body.And studies of heart stem cells show these can be killed by the virus. Cell Biologist Stefanie Dimmeler from the University of Frankfurt says this finding could prove useful in providing treatment and preventative medicine.A massive research project in China has identified over 700 different types of coronavirus carried by bats, some of these obscure virus sequences are thought to have already jumped from bats to human and animals such as pigs. In a similar way to SARS-CoV-2 they present a potential threat as a source of future pandemics says Peter Daszak from the EcoHeath Alliance which conducted the research in collaboration with Chinese scientists. And is there racism in the way people with Covid -19 infections are categorised? It’s an issue which concerns toxicologist Winston Morgan from the University of East London. He says as race is a social construct it’s an inappropriate measure to use when trying to work out who is vulnerable to the virus.And, Have you ever broken up a fight? Or pushed someone out the way of an oncoming vehicle, only to be hit by it yourself? Most of us probably haven’t taken as many risks as listener Alix, who has put herself in peril to save strangers on several occasions, and she wants Crowdscience to investigate why? At a time when medical professionals have to weigh up the personal dangers of working on the frontline of the Coronavirus crisis, it’s a particularly timely question. Marnie Chesterton finds out why it’s a good thing that children push the boundaries of what’s safe during playtime, because it makes them less anxious adults. And she questions the existence of the so-called bystander effect, discovering how evolution has ensured we’re a much braver species than we sometimes give ourselves credit for. But she hears from some social scientists who say there’s no such thing as a ‘hero’ however likely they are to intervene to help others

The number of cases of Covid -19 infections in Brazil and deaths related to the pandemic may be much higher than official figures show. Testing of the living is not widespread and there are few resources for analysing the potential role of the virus as a cause of death. Virologist Fernando Spiliki gives us his bleak assessment.A remarkable study from South Africa shows just how easily the virus can spread around a hospital, with a single infected person infecting many. However the route of infection is not necessarily direct person to person transmission says investigator Richard Lessells from the University of KwaZulu Natal. And from London a study in a hospital with many Covid patients at the height of the pandemic supports the South African findings; Researchers found viral particles on surfaces and in the air says Professor Wendy Barclay from Imperial College. An early warning system for outbreaks of the virus or second waves may come from analysis of sewage, Jordan Peccia from Yale University analysed waste from his local sewage treatment works and found peaks in concentrations of the virus in the sludge occurred a few days before increases in hospital admissions.(Image: Supporters of Brazilian President Jair Bolsonaro wear face masks as they demonstrate against quarantine and social distancing measures imposed by governors and mayors to combat the new coronavirus outbreak and demand military intervention. Also this week, The kids take over. Our younger listeners are as curious as their parents, it seems, so presenter Marnie Chesterton seeks out the finest minds and attempts to answer a raft of their science questions, including why can’t you tickle yourself? Why don’t our eyebrows grow as long as the hair on our heads? Not content with humankind, these whizz kids have been pondering deeply about other animals. Ava, 9, from the UK wants to know if any other animals kill for fun, like some humans do.Not limited by planet Earth, these little thinkers have been contemplating even weightier questions. Joshua, 13, from Kenya wonders if our Solar System rotates around anything. And Seattle-based Michael, 10, puzzles over what would happen if a black hole collided with a wormhole.These and other mysteries are uncovered by Marnie and her experts.Credit: SERGIO LIMA/AFP via Getty Images)